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Title : 7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT)

Title : 7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT)

Description : Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.

Description : Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.

Fromsemester : Spring

Fromsemester : Spring

Fromyear : 2004

Fromyear : 2004

Creator :

Creator :

Date : 2004-08-20T11:34:52+05:00

Date : 2004-08-20T11:34:52+05:00

Relation : 7.340

Relation : 7.340

Language : en-US

Language : en-US

Subject : immunology

Subject : immunology

Subject : immune system

Subject : immune system

Subject : immune evasion

Subject : immune evasion

Subject : pathogen

Subject : pathogen

Subject : effector function

Subject : effector function

Subject : infections

Subject : infections

Subject : Human cytomegalovirus

Subject : Human cytomegalovirus

Subject : Human Immunodeficiency Virus

Subject : Human Immunodeficiency Virus

Subject : CD4 cells

Subject : CD4 cells

Subject : CD8 cells

Subject : CD8 cells

Subject : T cells

Subject : T cells

Subject : surace receptors

Subject : surace receptors

Subject : cell lysis

Subject : cell lysis

Subject : host-pathogen interactions

Subject : host-pathogen interactions

Subject : host surveillance

Subject : host surveillance

Subject : antibodies

Subject : antibodies

Subject : MHC class I

Subject : MHC class I

Subject : blood-borne pathogens

Subject : blood-borne pathogens

Subject : macrophages

Subject : macrophages

Subject : phagocytosis

Subject : phagocytosis

Subject : endocytosis

Subject : endocytosis

Subject : degradation

Subject : degradation

Subject : antigen

Subject : antigen

Subject : apoptosis

Subject : apoptosis

Subject : cytokines

Subject : cytokines

Subject : immune response

Subject : immune response