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Description

This participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. This course is designed for graduate students interested in an academic career, and anyone else interested in teaching. Topics include theories of adult learning; course development; promoting active learning, problem-solving, and critical thinking in students; communicating with a diverse student body; using educational technology to further learning; lecturing; creating effective tests and assignments; and assessment and evaluation. Students research and present a relevant topic of particular interest. The subject is appropriate for both novices and those with teaching experience. This participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. This course is designed for graduate students interested in an academic career, and anyone else interested in teaching. Topics include theories of adult learning; course development; promoting active learning, problem-solving, and critical thinking in students; communicating with a diverse student body; using educational technology to further learning; lecturing; creating effective tests and assignments; and assessment and evaluation. Students research and present a relevant topic of particular interest. The subject is appropriate for both novices and those with teaching experience.Subjects

teaching | teaching | college-level science and engineering | college-level science and engineering | teaching equations | teaching equations | designing exam questions | designing exam questions | absorbing lectures | absorbing lectures | evils of PowerPoint | evils of PowerPoint | planning a course | planning a course | politics in academia | politics in academia | teaching for change | teaching for change | teaching with blackboards and slides | teaching with blackboards and slides | lecture performance | lecture performance | course design | course designLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadata16.225 Computational Mechanics of Materials (MIT) 16.225 Computational Mechanics of Materials (MIT)

Description

16.225 is a graduate level course on Computational Mechanics of Materials. The primary focus of this course is on the teaching of state-of-the-art numerical methods for the analysis of the nonlinear continuum response of materials. The range of material behavior considered in this course includes: linear and finite deformation elasticity, inelasticity and dynamics. Numerical formulation and algorithms include: variational formulation and variational constitutive updates, finite element discretization, error estimation, constrained problems, time integration algorithms and convergence analysis. There is a strong emphasis on the (parallel) computer implementation of algorithms in programming assignments. The application to real engineering applications and problems in engineering science is 16.225 is a graduate level course on Computational Mechanics of Materials. The primary focus of this course is on the teaching of state-of-the-art numerical methods for the analysis of the nonlinear continuum response of materials. The range of material behavior considered in this course includes: linear and finite deformation elasticity, inelasticity and dynamics. Numerical formulation and algorithms include: variational formulation and variational constitutive updates, finite element discretization, error estimation, constrained problems, time integration algorithms and convergence analysis. There is a strong emphasis on the (parallel) computer implementation of algorithms in programming assignments. The application to real engineering applications and problems in engineering science isSubjects

Computational Mechanics | Computational Mechanics | Computation | Computation | Mechanics | Mechanics | Materials | Materials | Numerical Methods | Numerical Methods | Numerical | Numerical | Nonlinear Continuum Response | Nonlinear Continuum Response | Continuum | Continuum | Deformation | Deformation | Elasticity | Elasticity | Inelasticity | Inelasticity | Dynamics | Dynamics | Variational Formulation | Variational Formulation | Variational Constitutive Updates | Variational Constitutive Updates | Finite Element | Finite Element | Discretization | Discretization | Error Estimation | Error Estimation | Constrained Problems | Constrained Problems | Time Integration | Time Integration | Convergence Analysis | Convergence Analysis | Programming | Programming | Continuum Response | Continuum Response | Computational | Computational | state-of-the-art | state-of-the-art | methods | methods | modeling | modeling | simulation | simulation | mechanical | mechanical | response | response | engineering | engineering | aerospace | aerospace | civil | civil | material | material | science | science | biomechanics | biomechanics | behavior | behavior | finite | finite | deformation | deformation | elasticity | elasticity | inelasticity | inelasticity | contact | contact | friction | friction | coupled | coupled | numerical | numerical | formulation | formulation | algorithms | algorithms | Variational | Variational | constitutive | constitutive | updates | updates | element | element | discretization | discretization | mesh | mesh | generation | generation | error | error | estimation | estimation | constrained | constrained | problems | problems | time | time | convergence | convergence | analysis | analysis | parallel | parallel | computer | computer | implementation | implementation | programming | programming | assembly | assembly | equation-solving | equation-solving | formulating | formulating | implementing | implementing | complex | complex | approximations | approximations | equations | equations | motion | motion | dynamic | dynamic | deformations | deformations | continua | continua | plasticity | plasticity | rate-dependency | rate-dependency | integration | integrationLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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This course is a student-presented seminar in combinatorics, graph theory, and discrete mathematics in general. Instruction and practice in written and oral communication is emphasized, with participants reading and presenting papers from recent mathematics literature and writing a final paper in a related topic. This course is a student-presented seminar in combinatorics, graph theory, and discrete mathematics in general. Instruction and practice in written and oral communication is emphasized, with participants reading and presenting papers from recent mathematics literature and writing a final paper in a related topic.Subjects

discrete math; discrete mathematics; discrete; math; mathematics; seminar; presentations; student presentations; oral; communication; stable marriage; dych; emergency; response vehicles; ambulance; game theory; congruences; color theorem; four color; cake cutting; algorithm; RSA; encryption; numberical integration; sorting; post correspondence problem; PCP; ramsey; van der waals; fibonacci; recursion; domino; tiling; towers; hanoi; pigeonhole; principle; matrix; hamming; code; hat game; juggling; zero-knowledge; proof; repeated games; lewis carroll; determinants; infinitude of primes; bridges; konigsberg; koenigsberg; time series analysis; GARCH; rational; recurrence; relations; digital; image; compression; quantum computing | discrete math; discrete mathematics; discrete; math; mathematics; seminar; presentations; student presentations; oral; communication; stable marriage; dych; emergency; response vehicles; ambulance; game theory; congruences; color theorem; four color; cake cutting; algorithm; RSA; encryption; numberical integration; sorting; post correspondence problem; PCP; ramsey; van der waals; fibonacci; recursion; domino; tiling; towers; hanoi; pigeonhole; principle; matrix; hamming; code; hat game; juggling; zero-knowledge; proof; repeated games; lewis carroll; determinants; infinitude of primes; bridges; konigsberg; koenigsberg; time series analysis; GARCH; rational; recurrence; relations; digital; image; compression; quantum computing | discrete math | discrete math | discrete mathematics | discrete mathematics | discrete | discrete | math | math | mathematics | mathematics | seminar | seminar | presentations | presentations | student presentations | student presentations | oral | oral | communication | communication | stable marriage | stable marriage | dych | dych | emergency | emergency | response vehicles | response vehicles | ambulance | ambulance | game theory | game theory | congruences | congruences | color theorem | color theorem | four color | four color | cake cutting | cake cutting | algorithm | algorithm | RSA | RSA | encryption | encryption | numberical integration | numberical integration | sorting | sorting | post correspondence problem | post correspondence problem | PCP | PCP | ramsey | ramsey | van der waals | van der waals | fibonacci | fibonacci | recursion | recursion | domino | domino | tiling | tiling | towers | towers | hanoi | hanoi | pigeonhole | pigeonhole | principle | principle | matrix | matrix | hamming | hamming | code | code | hat game | hat game | juggling | juggling | zero-knowledge | zero-knowledge | proof | proof | repeated games | repeated games | lewis carroll | lewis carroll | determinants | determinants | infinitude of primes | infinitude of primes | bridges | bridges | konigsberg | konigsberg | koenigsberg | koenigsberg | time series analysis | time series analysis | GARCH | GARCH | rational | rational | recurrence | recurrence | relations | relations | digital | digital | image | image | compression | compression | quantum computing | quantum computingLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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Wavelets are localized basis functions, good for representing short-time events. The coefficients at each scale are filtered and subsampled to give coefficients at the next scale. This is Mallat's pyramid algorithm for multiresolution, connecting wavelets to filter banks. Wavelets and multiscale algorithms for compression and signal/image processing are developed. Subject is project-based for engineering and scientific applications. Wavelets are localized basis functions, good for representing short-time events. The coefficients at each scale are filtered and subsampled to give coefficients at the next scale. This is Mallat's pyramid algorithm for multiresolution, connecting wavelets to filter banks. Wavelets and multiscale algorithms for compression and signal/image processing are developed. Subject is project-based for engineering and scientific applications.Subjects

Discrete-time filters | Discrete-time filters | convolution | convolution | Fourier transform | Fourier transform | owpass and highpass filters | owpass and highpass filters | Sampling rate change operations | Sampling rate change operations | upsampling and downsampling | upsampling and downsampling | ractional sampling | ractional sampling | interpolation | interpolation | Filter Banks | Filter Banks | time domain (Haar example) and frequency domain | time domain (Haar example) and frequency domain | conditions for alias cancellation and no distortion | conditions for alias cancellation and no distortion | perfect reconstruction | perfect reconstruction | halfband filters and possible factorizations | halfband filters and possible factorizations | Modulation and polyphase representations | Modulation and polyphase representations | Noble identities | Noble identities | block Toeplitz matrices and block z-transforms | block Toeplitz matrices and block z-transforms | polyphase examples | polyphase examples | Matlab wavelet toolbox | Matlab wavelet toolbox | Orthogonal filter banks | Orthogonal filter banks | paraunitary matrices | paraunitary matrices | orthogonality condition (Condition O) in the time domain | orthogonality condition (Condition O) in the time domain | modulation domain and polyphase domain | modulation domain and polyphase domain | Maxflat filters | Maxflat filters | Daubechies and Meyer formulas | Daubechies and Meyer formulas | Spectral factorization | Spectral factorization | Multiresolution Analysis (MRA) | Multiresolution Analysis (MRA) | requirements for MRA | requirements for MRA | nested spaces and complementary spaces; scaling functions and wavelets | nested spaces and complementary spaces; scaling functions and wavelets | Refinement equation | Refinement equation | iterative and recursive solution techniques | iterative and recursive solution techniques | infinite product formula | infinite product formula | filter bank approach for computing scaling functions and wavelets | filter bank approach for computing scaling functions and wavelets | Orthogonal wavelet bases | Orthogonal wavelet bases | connection to orthogonal filters | connection to orthogonal filters | orthogonality in the frequency domain | orthogonality in the frequency domain | Biorthogonal wavelet bases | Biorthogonal wavelet bases | Mallat pyramid algorithm | Mallat pyramid algorithm | Accuracy of wavelet approximations (Condition A) | Accuracy of wavelet approximations (Condition A) | vanishing moments | vanishing moments | polynomial cancellation in filter banks | polynomial cancellation in filter banks | Smoothness of wavelet bases | Smoothness of wavelet bases | convergence of the cascade algorithm (Condition E) | convergence of the cascade algorithm (Condition E) | splines | splines | Bases vs. frames | Bases vs. frames | Signal and image processing | Signal and image processing | finite length signals | finite length signals | boundary filters and boundary wavelets | boundary filters and boundary wavelets | wavelet compression algorithms | wavelet compression algorithms | Lifting | Lifting | ladder structure for filter banks | ladder structure for filter banks | factorization of polyphase matrix into lifting steps | factorization of polyphase matrix into lifting steps | lifting form of refinement equationSec | lifting form of refinement equationSec | Wavelets and subdivision | Wavelets and subdivision | nonuniform grids | nonuniform grids | multiresolution for triangular meshes | multiresolution for triangular meshes | representation and compression of surfaces | representation and compression of surfaces | Numerical solution of PDEs | Numerical solution of PDEs | Galerkin approximation | Galerkin approximation | wavelet integrals (projection coefficients | moments and connection coefficients) | wavelet integrals (projection coefficients | moments and connection coefficients) | convergence | convergence | Subdivision wavelets for integral equations | Subdivision wavelets for integral equations | Compression and convergence estimates | Compression and convergence estimates | M-band wavelets | M-band wavelets | DFT filter banks and cosine modulated filter banks | DFT filter banks and cosine modulated filter banks | Multiwavelets | MultiwaveletsLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadata11.946J Beijing Urban Design Studio (MIT) 11.946J Beijing Urban Design Studio (MIT)

Description

The Beijing Urban Design Studio is a joint program between the MIT and Tsinghua University Schools of Architecture and Planning. The goal of the studio is to foster international cooperation through the undertaking of a joint urban design and planning initiative in the city of Beijing involving important, often controversial, sites and projects. Since 1995, almost 250 MIT and Tsinghua University students and faculty have participated in this annual studio, making it one of the most successful and enduring international academic programs between China and the US. It has received the Irwin Sizer Award from MIT for outstanding innovation in education. The studio takes place over five weeks in June and July including several weeks in residence at Tsinghua University and two brie The Beijing Urban Design Studio is a joint program between the MIT and Tsinghua University Schools of Architecture and Planning. The goal of the studio is to foster international cooperation through the undertaking of a joint urban design and planning initiative in the city of Beijing involving important, often controversial, sites and projects. Since 1995, almost 250 MIT and Tsinghua University students and faculty have participated in this annual studio, making it one of the most successful and enduring international academic programs between China and the US. It has received the Irwin Sizer Award from MIT for outstanding innovation in education. The studio takes place over five weeks in June and July including several weeks in residence at Tsinghua University and two brieSubjects

China | China | Beijing | Beijing | Urban planning | Urban planning | International relations | International relations | Site planning | Site planning | Building use | Building use | Services | Services | Zoning | Zoning | Urban improvement | Urban improvement | Reuse | Reuse | Green building | Green building | Cultural understanding | Cultural understanding | 11.946 | 11.946 | 4.185 | 4.185License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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This course focuses on the use of modern computational and mathematical techniques in chemical engineering. Starting from a discussion of linear systems as the basic computational unit in scientific computing, methods for solving sets of nonlinear algebraic equations, ordinary differential equations, and differential-algebraic (DAE) systems are presented. Probability theory and its use in physical modeling is covered, as is the statistical analysis of data and parameter estimation. The finite difference and finite element techniques are presented for converting the partial differential equations obtained from transport phenomena to DAE systems. The use of these techniques will be demonstrated throughout the course in the MATLAB® computing environment. This course focuses on the use of modern computational and mathematical techniques in chemical engineering. Starting from a discussion of linear systems as the basic computational unit in scientific computing, methods for solving sets of nonlinear algebraic equations, ordinary differential equations, and differential-algebraic (DAE) systems are presented. Probability theory and its use in physical modeling is covered, as is the statistical analysis of data and parameter estimation. The finite difference and finite element techniques are presented for converting the partial differential equations obtained from transport phenomena to DAE systems. The use of these techniques will be demonstrated throughout the course in the MATLAB® computing environment.Subjects

Matlab | Matlab | modern computational techniques in chemical engineering | modern computational techniques in chemical engineering | mathematical techniques in chemical engineering | mathematical techniques in chemical engineering | linear systems | linear systems | scientific computing | scientific computing | solving sets of nonlinear algebraic equations | solving sets of nonlinear algebraic equations | solving ordinary differential equations | solving ordinary differential equations | solving differential-algebraic (DAE) systems | solving differential-algebraic (DAE) systems | probability theory | probability theory | use of probability theory in physical modeling | use of probability theory in physical modeling | statistical analysis of data estimation | statistical analysis of data estimation | statistical analysis of parameter estimation | statistical analysis of parameter estimation | finite difference techniques | finite difference techniques | finite element techniques | finite element techniques | converting partial differential equations | converting partial differential equationsLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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This course is a student-presented seminar in combinatorics, graph theory, and discrete mathematics in general. Instruction and practice in written and oral communication is emphasized, with participants reading and presenting papers from recent mathematics literature and writing a final paper in a related topic. This course is a student-presented seminar in combinatorics, graph theory, and discrete mathematics in general. Instruction and practice in written and oral communication is emphasized, with participants reading and presenting papers from recent mathematics literature and writing a final paper in a related topic.Subjects

discrete math; discrete mathematics; discrete; math; mathematics; seminar; presentations; student presentations; oral; communication; stable marriage; dych; emergency; response vehicles; ambulance; game theory; congruences; color theorem; four color; cake cutting; algorithm; RSA; encryption; numberical integration; sorting; post correspondence problem; PCP; ramsey; van der waals; fibonacci; recursion; domino; tiling; towers; hanoi; pigeonhole; principle; matrix; hamming; code; hat game; juggling; zero-knowledge; proof; repeated games; lewis carroll; determinants; infinitude of primes; bridges; konigsberg; koenigsberg; time series analysis; GARCH; rational; recurrence; relations; digital; image; compression; quantum computing | discrete math; discrete mathematics; discrete; math; mathematics; seminar; presentations; student presentations; oral; communication; stable marriage; dych; emergency; response vehicles; ambulance; game theory; congruences; color theorem; four color; cake cutting; algorithm; RSA; encryption; numberical integration; sorting; post correspondence problem; PCP; ramsey; van der waals; fibonacci; recursion; domino; tiling; towers; hanoi; pigeonhole; principle; matrix; hamming; code; hat game; juggling; zero-knowledge; proof; repeated games; lewis carroll; determinants; infinitude of primes; bridges; konigsberg; koenigsberg; time series analysis; GARCH; rational; recurrence; relations; digital; image; compression; quantum computing | discrete math | discrete math | discrete mathematics | discrete mathematics | discrete | discrete | math | math | mathematics | mathematics | seminar | seminar | presentations | presentations | student presentations | student presentations | oral | oral | communication | communication | stable marriage | stable marriage | dych | dych | emergency | emergency | response vehicles | response vehicles | ambulance | ambulance | game theory | game theory | congruences | congruences | color theorem | color theorem | four color | four color | cake cutting | cake cutting | algorithm | algorithm | RSA | RSA | encryption | encryption | numberical integration | numberical integration | sorting | sorting | post correspondence problem | post correspondence problem | PCP | PCP | ramsey | ramsey | van der waals | van der waals | fibonacci | fibonacci | recursion | recursion | domino | domino | tiling | tiling | towers | towers | hanoi | hanoi | pigeonhole | pigeonhole | principle | principle | matrix | matrix | hamming | hamming | code | code | hat game | hat game | juggling | juggling | zero-knowledge | zero-knowledge | proof | proof | repeated games | repeated games | lewis carroll | lewis carroll | determinants | determinants | infinitude of primes | infinitude of primes | bridges | bridges | konigsberg | konigsberg | koenigsberg | koenigsberg | time series analysis | time series analysis | GARCH | GARCH | rational | rational | recurrence | recurrence | relations | relations | digital | digital | image | image | compression | compression | quantum computing | quantum computingLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadataPassenger locomotive for the London & North Eastern Railway Company

Description

An image of a passenger locomotive, one of 13 ordered by the London & North Eastern Railway Company in 1924 (TWAM ref. DS.RSH/1/1/4). Engine nos. 3616-3628. Built for: London & North Eastern Railway Company. Date ordered 4 December 1924. Gauge of Railway: 4 feet 8½ inches. Principal Dimensions. Cylinders dia: 20 inches. Cylinders stroke: 26 inches. Wheels (Dia. of coupled): 5 feet 7 inches. Wheel-base - total: 33 feet 1 inch. Water capacity: 2100 gallons. Fuel capacity: 180 cubic feet = 4 tons. Heating surface ? total: 1280 square feet. Grate area: 21 square feet. Working pressure: 180 lbs per square inch. Total weight in working order: 90.51 tons. Tractive force taking 90% of the working pressure: 25137 lbs. Tractive force taking 75% of the working pressure: 20947 lbs. Approximate shipping space: not given. Approximate gross weight packed for shipment: not given. Code Word: GORTON This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | engineering | engines | interesting | historic | passengerlocomotive | lner | londonnortheasternrailwaycompany | rail | railway | industrialheritage | archives | digitalimage | blackandwhitephotograph | hawthornleslielocomotives | carriage | wheel | london | northeasternrailwaycompany | 1924 | engine | cylinder | hawthornleslielocomotiveworks | forthbanks | northeastofengland | unitedkingdom | transportation | unusual | fascinating | impressive | striking | roberthawthorn | williamhawthorn | 1820 | partnership | manufacture | stationaryengines | marineengineering | locomotiveengine | stocktonrailway | darlingtonrailway | randwhawthornlesliecoltd | 1885 | hebburn | andrewleslie | neutralbackground | pipe | metal | bolt | panel | doorway | window | handle | vent | lner1784 | mark | grain | groundLicense

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See all metadataTank engine for the Weardale Lead Company

Description

An image of a tank engine, ordered by the Weardale Lead Company in April 1913 (TWAM ref. DS.RSH/1/1/3). Engine no. 3029. Built for: Weardale Lead Company. Date ordered 2 April 1913. Gauge of Railway: 1 foot 10 inches. Principal Dimensions. Cylinders dia: 5 inches. Cylinders stroke: 10 inches. Wheels (Dia. of coupled): 1 foot 8½ inches. Wheel-base - total: 3 feet. Water capacity: 65 gallons. Fuel capacity: not given. Heating surface ? total: 74 square feet. Grate area: 2 square feet. Working pressure: 140 lbs per square inch. Total weight in working order: 4.25 tons. Tractive force taking 90% of the working pressure: 1536 lbs. Tractive force taking 75% of the working pressure: 1280 lbs. Approximate shipping space: 372 cubic feet. Approximate gross weight packed for shipment: 3.795 tons. Code Word: GANDA This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | weardaleleadcompany | engineering | engines | mechanical | machine | wheel | parts | hawthornleslielocomotives | cabin | doorway | industrialheritage | engine | motor | april1913 | engineno3029 | cylinders | hawthornleslielocomotiveworks | roberthawthorn | january1817 | partnership | 1820 | williamhawthorn | stocktonanddarlingtonrailway | railway | construction | development | building | digitalimage | rail | bolt | panel | inscription | plate | pipe | roof | lid | handle | neutralbackground | mark | grain | fascinating | impressive | unusual | interesting | hook | stone | ground | metal | track | sepia | blackandwhite | photograph | northeastofengland | unitedkingdom | equipment | motto | transport | transportationLicense

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See all metadataSaddle Tank Engine for the South Metropolitan Gas Company

Description

An image of a saddle tank engine, one of two ordered for the South Metropolitan Gas Company, London in May 1909 (TWAM ref. DS.RSH/1/1/3). Engine nos. 2790-2791. Built for: South Metropolitan Gas Company. Date ordered 14 May 1909. Gauge of Railway: 4 feet 8½ inches. Principal Dimensions. Cylinders dia: 10 inches. Cylinders stroke: 15 inches. Wheels (Dia. of coupled): 2 feet 10 inches. Wheel-base - total: 5 feet. Water capacity: 350 gallons. Fuel capacity: 25 cubic feet = 0.55 tons. Heating surface ? total: 300 square feet. Grate area: 6 square feet. Working pressure: 150 lbs per square inch. Total weight in working order: 16.75 tons. Tractive force taking 90% of the working pressure: 5558 lbs. Tractive force taking 75% of the working pressure: 4632 lbs. Approximate shipping space: 1455 cubic feet. Approximate gross weight packed for shipment: 15 tons. Code Word: MET This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | southmetropolitangascompany | engineering | engines | hawthornleslielocomotives | rail | wheel | blackandwhitephotograph | archives | digitalimage | industrialheritage | northeastofengland | unitedkingdom | interesting | unusual | fascinating | impressive | railroad | equipment | engine | saddletankengine | london | railway | cylinder | transportation | 14may1909 | hawthornleslielocomotiveworks | forthbanks | roberthawthorn | january1817 | 1820 | partnership | williamhawthorn | manufacturing | locomotiveengine | 1831 | stocktonrailway | darlingtonrailway | 1882 | 1885 | randwhawthornlesliecoltd | production | construction | earlytwentiethcentury | stone | sand | debris | motto | label | neutralbackground | grain | mark | bolt | panel | parts | handle | step | light | mechanical | machine | pipe | blur | sepia | doorway | window | roof | controlsLicense

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See all metadataCrane locomotive built in Newcastle upon Tyne

Description

An image of a crane locomotive ordered by Mr Hanning, Paris in 1909 (TWAM ref. DS.RSH/1/2). Engine no. 2783. Built for: Mr Hanning, Paris. Date ordered: 30 March 1909. Gauge of Railway: 4 feet 8½ inches. Principal Dimensions. Cylinders dia: 12 inches. Cylinders stroke: 15 inches. Wheels (Dia. of coupled): 2 feet 10 inches. Wheel-base - total: 6 feet. Water capacity: 450 gallons. Fuel capacity: 15 cubic feet = 0.35 tons. Heating surface ? total: 316.5 square feet. Grate area: 8 square feet. Working pressure: 180 lbs per square inch. Total weight in working order: 26 tons. Tractive force taking 90% of the working pressure: 10295 lbs. Tractive force taking 75% of the working pressure: 8590 lbs. Approximate shipping space: 1976 cubic feet. Approximate gross weight packed for shipment: 25.4 tons. Code Word: HAWTHORN This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | engineering | engines | interesting | historic | paris | cranelocomotive | blackandwhitephotograph | sepia | digitalimage | industrialheritage | hawthornleslielocomotives | crane | mrhanning | france | 30march1909 | cylinder | wheel | hawthornleslielocomotiveworks | forthbanks | northeastofengland | unitedkingdom | rail | railway | roberthawthorn | williamhawthorn | manufacturing | engine | locomotiveengine | stocktonrailway | darlingtonrailway | construction | development | structure | signage | letters | unusual | fascinating | impressive | lever | step | doorway | grain | mark | ground | neutralbackground | weight | pipe | bolt | panel | parts | guard | groove | hook | cabin | hawthorn | archivesLicense

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See all metadataDescription

This participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. This course is designed for graduate students interested in an academic career, and anyone else interested in teaching. Readings and discussions include: teaching equations for understanding, designing exam and homework questions, incorporating histories of science, creating absorbing lectures, teaching for transfer, the evils of PowerPoint, and planning a course. The subject is appropriate for both novices and those with teaching experience. This participatory seminar focuses on the knowledge and skills necessary for teaching science and engineering in higher education. This course is designed for graduate students interested in an academic career, and anyone else interested in teaching. Readings and discussions include: teaching equations for understanding, designing exam and homework questions, incorporating histories of science, creating absorbing lectures, teaching for transfer, the evils of PowerPoint, and planning a course. The subject is appropriate for both novices and those with teaching experience.Subjects

teaching | teaching | college-level science and engineering | college-level science and engineering | teaching equations | teaching equations | designing exam questions | designing exam questions | absorbing lectures | absorbing lectures | evils of PowerPoint | evils of PowerPoint | planning a course | planning a course | politics in academia | politics in academia | teaching for change | teaching for change | teaching with blackboards and slides | teaching with blackboards and slides | lecture performance | lecture performance | course design | course designLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadata3.042 Materials Project Laboratory (MIT) 3.042 Materials Project Laboratory (MIT)

Description

As its name implies, the 3.042 Materials Project Laboratory involves working with such operations as investment casting of metals, injection molding of polymers, and sintering of ceramics. After all the abstraction and theory in the lecture part of the DMSE curriculum, many students have found this hands-on experience with materials to be very fun stuff - several have said that 3.042/3.082 was their favorite DMSE subject. The lab is more than operating processing equipment, however. It is intended also to emulate professional practice in materials engineering project management, with aspects of design, analysis, teamwork, literature and patent searching, Web creation and oral presentation, and more. As its name implies, the 3.042 Materials Project Laboratory involves working with such operations as investment casting of metals, injection molding of polymers, and sintering of ceramics. After all the abstraction and theory in the lecture part of the DMSE curriculum, many students have found this hands-on experience with materials to be very fun stuff - several have said that 3.042/3.082 was their favorite DMSE subject. The lab is more than operating processing equipment, however. It is intended also to emulate professional practice in materials engineering project management, with aspects of design, analysis, teamwork, literature and patent searching, Web creation and oral presentation, and more.Subjects

Student project teams design and fabricate a materials engineering prototype using processing technologies (injection molding | Student project teams design and fabricate a materials engineering prototype using processing technologies (injection molding | thermoforming | thermoforming | investment casting | investment casting | powder processing | powder processing | three-dimensional printing | three-dimensional printing | physical vapor deposition | physical vapor deposition | etc.) appropriate for the materials and device of interest. Goals include using MSE fundamentals in a practical application; understanding trade-offs between design | etc.) appropriate for the materials and device of interest. Goals include using MSE fundamentals in a practical application; understanding trade-offs between design | processing and performance; and fabrication of a deliverable prototype. Emphasis on teamwork | processing and performance; and fabrication of a deliverable prototype. Emphasis on teamwork | project management | project management | communications and computer skills | communications and computer skills | and hands-on work using student and MIT laboratory shops. Teams document their progress and final results by means of web pages and weekly oral presentations. Instruction and practice in oral communication provided. | and hands-on work using student and MIT laboratory shops. Teams document their progress and final results by means of web pages and weekly oral presentations. Instruction and practice in oral communication provided.License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadata14.121 Microeconomic Theory I (MIT) 14.121 Microeconomic Theory I (MIT)

Description

This half-semester course provides an introduction to microeconomic theory designed to meet the needs of students in the economics Ph.D. program. Some parts of the course are designed to teach material that all graduate students should know. Others are used to introduce methodologies. Topics include consumer and producer theory, markets and competition, general equilibrium, and tools of comparative statics and their application to price theory. Some topics of recent interest may also be covered. This half-semester course provides an introduction to microeconomic theory designed to meet the needs of students in the economics Ph.D. program. Some parts of the course are designed to teach material that all graduate students should know. Others are used to introduce methodologies. Topics include consumer and producer theory, markets and competition, general equilibrium, and tools of comparative statics and their application to price theory. Some topics of recent interest may also be covered.Subjects

microeconomic theory | microeconomic theory | demand theory | demand theory | producer theory; partial equilibrium | producer theory; partial equilibrium | competitive markets | competitive markets | general equilibrium | general equilibrium | externalities | externalities | Afriat's theorem | Afriat's theorem | pricing | pricing | robust comparative statics | robust comparative statics | utility theory | utility theory | properties of preferences | properties of preferences | choice as primitive | choice as primitive | revealed preference | revealed preference | classical demand theory | classical demand theory | Kuhn-Tucker necessary conditions | Kuhn-Tucker necessary conditions | implications of Walras?s law | implications of Walras?s law | indirect utility functions | indirect utility functions | theorem of the maximum (Berge?s theorem) | theorem of the maximum (Berge?s theorem) | expenditure minimization problem | expenditure minimization problem | Hicksian demands | Hicksian demands | compensated law of demand | compensated law of demand | Slutsky substitution | Slutsky substitution | price changes and welfare | price changes and welfare | compensating variation | compensating variation | and welfare from new goods | and welfare from new goods | price indexes | price indexes | bias in the U.S. consumer price index | bias in the U.S. consumer price index | integrability | integrability | demand aggregation | demand aggregation | aggregate demand and welfare | aggregate demand and welfare | Frisch demands | Frisch demands | and demand estimation | and demand estimation | increasing differences | increasing differences | producer theory applications | producer theory applications | the LeCh?telier principle | the LeCh?telier principle | Topkis? theorem | Topkis? theorem | Milgrom-Shannon monotonicity theorem | Milgrom-Shannon monotonicity theorem | monopoly pricing | monopoly pricing | monopoly and product quality | monopoly and product quality | nonlinear pricing | nonlinear pricing | and price discrimination | and price discrimination | simple models of externalities | simple models of externalities | government intervention | government intervention | Coase theorem | Coase theorem | Myerson-Sattherthwaite proposition | Myerson-Sattherthwaite proposition | missing markets | missing markets | price vs. quantity regulations | price vs. quantity regulations | Weitzman?s analysis | Weitzman?s analysis | uncertainty | uncertainty | common property externalities | common property externalities | optimization | optimization | equilibrium number of boats | equilibrium number of boats | welfare theorems | welfare theorems | uniqueness and determinacy | uniqueness and determinacy | price-taking assumption | price-taking assumption | Edgeworth box | Edgeworth box | welfare properties | welfare properties | Pareto efficiency | Pareto efficiency | Walrasian equilibrium with transfers | Walrasian equilibrium with transfers | Arrow-Debreu economy | Arrow-Debreu economy | separating hyperplanes | separating hyperplanes | Minkowski?s theorem | Minkowski?s theorem | Existence of Walrasian equilibrium | Existence of Walrasian equilibrium | Kakutani?s fixed point theorem | Kakutani?s fixed point theorem | Debreu-Gale-Kuhn-Nikaido lemma | Debreu-Gale-Kuhn-Nikaido lemma | additional properties of general equilibrium | additional properties of general equilibrium | Microfoundations | Microfoundations | core | core | core convergence | core convergence | general equilibrium with time and uncertainty | general equilibrium with time and uncertainty | Jensen?s inequality | Jensen?s inequality | and security market economy | and security market economy | arbitrage pricing theory | arbitrage pricing theory | and risk-neutral probabilities | and risk-neutral probabilities | Housing markets | Housing markets | competitive equilibrium | competitive equilibrium | one-sided matching house allocation problem | one-sided matching house allocation problem | serial dictatorship | serial dictatorship | two-sided matching | two-sided matching | marriage markets | marriage markets | existence of stable matchings | existence of stable matchings | incentives | incentives | housing markets core mechanism | housing markets core mechanismLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadataDescription

This course investigates theories and practices of feminist inquiry across a range of disciplines. Feminist research involves rethinking disciplinary assumptions and methodologies, developing new understandings of what counts as knowledge, seeking alternative ways of understanding the origins of problems/issues, formulating new ways of asking questions and redefining the relationship between subjects and objects of study. What makes research distinctively feminist lies in the complex connections between epistemologies, methodologies and research methods. This course explores how these connections are formed in the traditional disciplines and raise questions about why they are inadequate and/or problematic for feminist inquiry and what, specifically, are the feminist critiques of these int This course investigates theories and practices of feminist inquiry across a range of disciplines. Feminist research involves rethinking disciplinary assumptions and methodologies, developing new understandings of what counts as knowledge, seeking alternative ways of understanding the origins of problems/issues, formulating new ways of asking questions and redefining the relationship between subjects and objects of study. What makes research distinctively feminist lies in the complex connections between epistemologies, methodologies and research methods. This course explores how these connections are formed in the traditional disciplines and raise questions about why they are inadequate and/or problematic for feminist inquiry and what, specifically, are the feminist critiques of these intSubjects

feminism | feminism | feminist | feminist | inquiry | inquiry | feminist inquiry | feminist inquiry | globalization | globalization | interdiscipline | interdiscipline | research | research | methods | methods | politics | politics | poststructuralism | poststructuralism | narration | narration | representation of the body | representation of the body | production | production | reproduction | reproduction | identity | identity | third wave feminism | third wave feminismLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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Numerical methods for solving problems arising in heat and mass transfer, fluid mechanics, chemical reaction engineering, and molecular simulation. Topics: numerical linear algebra, solution of nonlinear algebraic equations and ordinary differential equations, solution of partial differential equations (e.g. Navier-Stokes), numerical methods in molecular simulation (dynamics, geometry optimization). All methods are presented within the context of chemical engineering problems. Familiarity with structured programming is assumed. The examples will use MATLAB®. Acknowledgements The instructor would like to thank Robert Ashcraft, Sandeep Sharma, David Weingeist, and Nikolay Zaborenko for their work in preparing materials for this course site. Numerical methods for solving problems arising in heat and mass transfer, fluid mechanics, chemical reaction engineering, and molecular simulation. Topics: numerical linear algebra, solution of nonlinear algebraic equations and ordinary differential equations, solution of partial differential equations (e.g. Navier-Stokes), numerical methods in molecular simulation (dynamics, geometry optimization). All methods are presented within the context of chemical engineering problems. Familiarity with structured programming is assumed. The examples will use MATLAB®. Acknowledgements The instructor would like to thank Robert Ashcraft, Sandeep Sharma, David Weingeist, and Nikolay Zaborenko for their work in preparing materials for this course site.Subjects

Matlab | Matlab | modern computational techniques in chemical engineering | modern computational techniques in chemical engineering | mathematical techniques in chemical engineering | mathematical techniques in chemical engineering | linear systems | linear systems | scientific computing | scientific computing | solving sets of nonlinear algebraic equations | solving sets of nonlinear algebraic equations | solving ordinary differential equations | solving ordinary differential equations | solving differential-algebraic (DAE) systems | solving differential-algebraic (DAE) systems | probability theory | probability theory | use of probability theory in physical modeling | use of probability theory in physical modeling | statistical analysis of data estimation | statistical analysis of data estimation | statistical analysis of parameter estimation | statistical analysis of parameter estimation | finite difference techniques | finite difference techniques | finite element techniques | finite element techniques | converting partial differential equations | converting partial differential equations | Navier-Stokes equations | Navier-Stokes equationsLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadata21G.101 Chinese I (Regular) (MIT) 21G.101 Chinese I (Regular) (MIT)

Description

Includes audio/video content: AV faculty introductions. This subject is the first semester of four that forms an introduction to modern standard Chinese, commonly called Mandarin, the language with the largest number of native speakers in the world. It is the official language of Mainland China and Taiwan, and one of the official languages of Singapore. The course presupposes no prior background in the language. Course objectives are to master Mandarin pronunciation, including the recognition and writing of Pinyin romanization, basic reading and writing skills (around 150 characters in the traditional character set or the simplified set), and to develop the ability to participate in simple, practical conversations on everyday topics. The relationship between Chinese language and culture an Includes audio/video content: AV faculty introductions. This subject is the first semester of four that forms an introduction to modern standard Chinese, commonly called Mandarin, the language with the largest number of native speakers in the world. It is the official language of Mainland China and Taiwan, and one of the official languages of Singapore. The course presupposes no prior background in the language. Course objectives are to master Mandarin pronunciation, including the recognition and writing of Pinyin romanization, basic reading and writing skills (around 150 characters in the traditional character set or the simplified set), and to develop the ability to participate in simple, practical conversations on everyday topics. The relationship between Chinese language and culture anSubjects

Pinyin | Pinyin | modern standard Chinese | modern standard Chinese | Chinese pronunciation | Chinese pronunciation | Chinese 101 | Chinese 101 | learning Chinese | learning Chinese | basic Chinese | basic Chinese | Mandarin Chinese | Mandarin Chinese | Chinese Writing | Chinese Writing | Speaking Chinese | Speaking Chinese | traditional Chinese characters | traditional Chinese characters | simplified Chinese characters | simplified Chinese charactersLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadataLocomotive for Ashington Coal Company

Description

View of a side tank locomotive, one of two ordered by Ashington Coal Company in 1919 (TWAM ref. DS.RSH/1/1/4). Engine no. 3392-3393. Built for: Ashington Coal Company. Date ordered: 21 February 1919. Gauge of Railway: 4 feet 8½ inches. Principal Dimensions. Cylinders dia: 17 inches. Cylinders stroke: 24 inches. Wheels (Dia. of coupled): 4 feet 3 inches. Wheel-base - total: 12 feet 6 inches. Water capacity: 1000 gallons. Fuel capacity: 80 cubic feet = 1.75 tons. Heating surface ? total: 945 square feet. Grate area: 15.5 square feet. Working pressure: 160 lbs per square inch. Total weight in working order: 45.2 tons. Tractive force taking 90% of the working pressure: 19600 lbs. Tractive force taking 75% of the working pressure: 16320 lbs. Approximate shipping space: 3095 cubic feet. Approximate gross weight packed for shipment: 39.5 tons. Code Word: WARHAM This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | engineering | engines | interesting | historic | ashingtoncoalcompany | northumberland | northeastengland | transportation | blackandwhitephotograph | industrialheritage | digitalimage | archives | unusual | fascinating | hawthornleslielocomotives | northeastofengland | unitedkingdom | sidetank | sidetanklocomotive | 1919 | cylinder | wheel | shaft | vent | engine | hawthornleslielocomotiveworks | forthbanks | roberthawthorn | williamhawthorn | rail | railway | manufacture | neutralbackground | mark | grain | stone | blur | cabin | doorway | window | controls | handle | impressive | magnificentLicense

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This course introduces experimental biochemical and molecular techniques from a quantitative engineering perspective. Rigorous quantitative data collection, statistical analysis, and conceptual understanding of instrumentation design and application form the underpinnings of this course. The four discovery based modules include DNA Engineering, Protein Engineering, Systems Engineering, and Biomaterials Engineering. Additional information is available on the course Wiki (hosted on OpenWetWare.) Teaching Fellows Reshma Shetty Maria Foley Eileen Higham Yoon Sung Nam This course introduces experimental biochemical and molecular techniques from a quantitative engineering perspective. Rigorous quantitative data collection, statistical analysis, and conceptual understanding of instrumentation design and application form the underpinnings of this course. The four discovery based modules include DNA Engineering, Protein Engineering, Systems Engineering, and Biomaterials Engineering. Additional information is available on the course Wiki (hosted on OpenWetWare.) Teaching Fellows Reshma Shetty Maria Foley Eileen Higham Yoon Sung NamSubjects

biological engineering | biological engineering | biology | biology | bioengineering | bioengineering | DNA | DNA | PCR | PCR | RNA | RNA | polymerase chain reaction | polymerase chain reaction | systems engineering | systems engineering | DNA engineering | DNA engineering | protein engineering | protein engineering | bio-material engineering | bio-material engineering | restriction map | restriction map | lipofection | lipofection | screening library | screening library | bacterial photography | bacterial photography | device characterization | device characterization | biological parts | biological parts | openwetware | openwetwareLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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See all metadataSide tank engine 'Huaral' built by Hawthorn Leslie

Description

An image of the side tank engine 'Huaral' ordered in November 1910 for the North Eastern Railway of Peru (TWAM ref. DS.RSH/1/1/3). Engine nos. 2866-2868. Built for: North Eastern Railway of Peru. Date ordered 28 November 1910. Gauge of Railway: 3 feet. Principal Dimensions. Cylinders dia: 12½ inches. Cylinders stroke: 18 inches. Wheels (Dia. of coupled): 3 feet ½ inch. Wheel-base - total: 8 feet 6 inches. Water capacity: 600 gallons. Fuel capacity: 45 cubic feet = 1 ton. Heating surface ? total: 456 square feet. Grate area: 8 square feet. Working pressure: 165 lbs per square inch. Total weight in working order: 24.37 tons. Tractive force taking 90% of the working pressure: 11439 lbs. Tractive force taking 75% of the working pressure: 9533 lbs. Approximate shipping space: 2020 cubic feet. Approximate gross weight packed for shipment: 21.3 tons. Code Word: HUARAL This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | engineering | engines | interesting | historic | peru | blackandwhitephotograph | sepiaphotograph | industrialheritage | fascinating | impressive | unusual | sidetankengine | mechanical | huaral | november1910 | northeasternrailwayofperu | hawthornleslielocomotives | engine | rail | railway | 28november1910 | cylinder | wheel | transport | transportation | northeastofengland | unitedkingdom | hawthornleslielocomotiveworks | forthbanks | roberthawthorn | williamhawthorn | partnership | manufactured | locomotiveengine | stockton | darlingtonrailway | twentiethcentury | digitalimage | plate | letters | bolt | panel | handle | number | identification | light | chimney | vent | pipe | window | doorway | step | guard | parts | neutralbackground | grain | mark | shadow | stone | metal | bar | leverLicense

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See all metadataMary A. Marr, arrested for stealing a sailor's bag

Description

Name: Mary A. Marr Arrested for: not given Arrested at: North Shields Police Station Arrested on: 6 June 1906 Tyne and Wear Archives ref: DX1388-1-41-Mary A Marr For an image of her daughter Alice Maud Marr see www.flickr.com/photos/twm_news/16935100722/in/album-72157.... For an image of her son Charles Marr see www.flickr.com/photos/twm_news/16567211557/in/album-72157.... For an image of her daughter Mary Ellen Marr see www.flickr.com/photos/twm_news/17084333602/in/album-72157.... The Shields Daily News for 6 June 1906 reports: "THEFT OF A SAILOR'S BAG AT NORTH SHIELDS. At North Shields Police Court today Charles Marr, Mary Ann Marr, Mary Ellen Marr and Chas. Marr were charged with being concerned together in stealing a sailor's bag of clothing etc, valued at £2, the property of John Partis Gibson, a seaman. Supt. Jamieson of the BTP prosecuted. The prosecutor said that on the 7th May he joined the s.s. Camelia, which was then lying at the Commissioners? Staithes. He was proceeding to the docks with his bag and when passing the North Shields Railway Station the defendant Chas. Marr came up to him and offered to carry his bag for 1d. He said he would give him 3d if he carried it to the docks and he agreed to do so. He gave him the bag and told him he was going to make a purchase. On reaching his vessel he failed to see the boy and gave information to the police. He went to sea the same day and had just returned. Two pawnbrokers? assistants spoke to receiving a portion of the stolen clothing from two of the female defendants. Sub-Inspector Leitch said that on the 8th May, from information received, he made enquiries and proceeded to the North Shields Railway Station, where he found the boy Marr and questioned him. He told witness he took the bag home, being unable to find the man who had engaged him at the dock. He went to the house occupied by the defendants and spoke to Mrs Marr with regard to the bag. She told him it was in the cupboard. He took possession of it and found that it contained only a small portion of the stolen clothing. He mentioned this circumstance to her and she said it was just the same as it was when it was brought in the previous day and that it had not been touched. He searched the house and found a portion of the property and he recovered the remainder from the pawnbrokers. He added that the boy told the truth at once and had given him every assistance in recovering the property, while the mother had given him a great deal of trouble. Formally charged, the mother, Mary Ann Marr, said it would not have happened had it not been for need. Charles, who made his 13th appearance, was given the option of a fine, he having assisted the police, and he was mulcted in 1s without costs. Marry Ann Marr, whom the magistrates considered was the chief instigator in the theft, was committed to prison for 14 days, while Mary Ellen Marr was sentenced to 7 days imprisonment. Because of her youth, Alice Marr was discharged." The Shields Daily News for 24 January 1907 reports: "THEFT OF DOOR MATS. MOTHER AND DAUGHTERS SENT TO PRISON. At North Shields Police Court today Mary Ellen Marr (21), Alice Maud Marr (17), sisters, and Mary Ann Marr (44), their mother, were charged with having stolen an indiarubber door mat, valued at £1 4s, the property of Joseph Ostens, from the doorway of his house, 34 Grosvenor Place, on the 17th inst., or with having received the same, well knowing it to have been stolen. They were further charged with having stolen a similar mat, valued at £1 3s, from the doorway of No. 32 Grosvenor Place, on the 17th inst., the property of John R Sutherland. There was a third charge against Mary Ellen and Alice Maud of having stolen on the 21st ult., from the porch of Percy Park House, Grand Parade, Tynemouth, an indiarubber mat, valued at £1 10s, the property of Mr A. O. Carr, JP. In the first case, Detective Sergeant Hall said that on the 18th inst. he arrested the accused at their residence in Church Way. He found the mat produced cut to pieces in the kitchen. Afterwards it was identified by the prosecutor as his property. In the other cases, evidence was given to the effect that the two other mats had been similarly treated, and that one of them had been disposed of at a marine store dealer's for 3s 6d. Previous convictions against the accused were put in by the Chief Constable (Mr J. H. Huish) and the magistrates committed the mother to prison for 14 days on each of the two charges preferred against her and sent the daughters to gaol for 14 days on each of the three charges preferred against them." These images are a selection from an album of photographs of prisoners brought before the North Shields Police Court between 1902 and 1916 in the collection of Tyne & Wear Archives (TWA ref DX1388/1). (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

prisoner | crime | criminal | northshields | policestation | mugshot | imprisoned | arrested | hat | theft | stealing | woman | sad | punishment | northtyneside | interesting | unusual | portrait | socialhistory | criminalfacesofnorthshieldsthewomen | female | sailorsbag | maryamarr | 6june1906 | northshieldspolicestation | archives | digitalimage | sepiaphotograph | blackoutline | neutralbackground | mark | grain | fabric | ribbon | hand | finger | shoulder | face | head | hair | fascinating | northshieldspolicecourt | courthearing | newspaperreport | theshieldsdailynews | clothing | privateproperty | johnpartisgibson | seaman | charged | hardship | imprisonment | sscamelia | northshieldsrailwaystation | pawnbrokers | subinspectorleitch | boy | chiefinstigator | 24january1907 | daughters | maryellenmarr | alicemaudmarr | sisters | mother | maryannmarr | doormat | josephostens | johnrsutherland | mraocarrjp | detectivesergeanthall | chiefconstablemrjhhuish | 190216 | fine | charles | assistedpoliceLicense

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See all metadataSide Tank Engine for the Lagos Railway, Nigeria

Description

An image of one of two side tank engines ordered for the Lagos Railway, Nigeria in November 1910 (TWAM ref. DS.RSH/1/1/3). Engine nos. 2864-2865. Built for: Crown Agents for South Nigeria. Date ordered: 11 November 1910. Gauge of Railway: 3 feet 6 inches. Principal Dimensions. Cylinders dia: 14 inches. Cylinders stroke: 20 inches. Wheels (Dia. of coupled): 3 feet 4 inches. Wheel-base - total: 10 feet 6 inches. Water capacity: 660 gallons. Fuel capacity: 35 cubic feet = 0.8 tons. Heating surface ? total: 695 square feet. Grate area: 11.3 square feet. Working pressure: 160 lbs per square inch. Total weight in working order: 30.9 tons. Tractive force taking 90% of the working pressure: 14112 lbs. Tractive force taking 75% of the working pressure: 11760 lbs. Approximate shipping space: 2455 cubic feet. Approximate gross weight packed for shipment: 26.525 tons. Code Word: JEBBA This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | lagosrailway | nigeria | newcastleupontyne | engineering | sepiaphotograph | industrialheritage | digitalimage | carriage | engines | november1910 | sidetankengines | crownagents | southnigeria | hawthornleslielocomotiveworks | locomotives | hawthornleslielocomotives | steam | rail | railway | forthbanks | roberthawthorn | williamhawthorn | manufactured | stationaryengines | locomotiveengine | unusual | interesting | fascinating | construction | structure | wheel | parts | neutralbackground | mark | grain | debris | bolt | metal | cabin | doorway | letters | number | identification | cylinder | chimney | vent | piston | window | roof | body | transportationLicense

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See all metadataJohn T. Ingleson, soldier, arrested for breaking and entering

Description

Name: John T. Ingleson Arrested for: not given Arrested at: North Shields Police Station Arrested on: 30 March 1915 Tyne and Wear Archives ref: DX1388-1-260-John T Ingleson The Shields Daily News for 7 April 1915 reports: ?BREAKING AND ENTERING. SOLDIERS COMMITTED FOR TRIAL AT NORTH SHIELDS. Frederick Jones (19) and John Thomas Ingleson (19), soldiers, stationed at Earsdon, were brought up on remand at North Shields today charged with breaking and entering on the 30th March a dwelling house, situated at 9 Lovaine Terrace and stealing 16 knives, a cruet, clock, pair of scissors, case of needles, silver tray and two salt cellars valued at £3 7s 6d the property of the executors of the late Thomas Williamson. They were also charged with breaking and entering between 10pm on the 29th ult. and 7.45am on the 30th ult. a confectioner?s shop in Queen Alexandra Road and stealing two loaves of bread, valued at 7d, the property of Messrs Patterson and Reed. George Anderson, a cashier, identified the goods as the property of the executors of the late Mr Williamson. PC John Dixon stated that at 2.50am on the 30th ult. he found a window broken at 9 Lovaine Terrace. He lifted the sash and upon shining his lamp around the room he saw Jones behind a bookcase and the other man crouching in a corner. Witness arrested defendants and on searching them at the police station found the goods mentioned in their possession? Det.-Insp. said that on the morning of the 30th, from what Jones told him, he examined Messrs Patterson and Reed?s shop and found a large stone, which exactly fitted the break in the window. Afterwards witness jointly charged both men and Jones replied, ?We did it? and Ingleson said, ?I say the same?. When formally charged with the first offence Jones said, ?We took them? and Ingleson said, ?We wanted to get in there mostly to get some clothes?. Replying to the second charge, defendants both said they wanted something to eat. They were committed for trial at the Quarter Sessions and the magistrates complimented PC Dixon upon his smart capture. On the recommendation of Chief Constable Huish, the Watch Committee have granted the merit badge to PC Dixon.? The Shields Daily News for 9 April 1915 reports: ?SHOP BREAKING BY SOLDIERS AT NORTH SHIELDS Frederick Jones, 19, and John Thomas Ingleson, 19, privates in the Duke of Wellington?s First Riding Regiment, stationed at Earsdon, were charged with having broken into the unoccupied house of the late Mr Thomas Williamson, Lovaine House, Lovaine Terrace, North Shields on March 30 and with having stolen various goods, valued at £3 7s 6d. They were also charged with the theft of two loaves of bread from the confectionery shop of Messrs Patterson and Reed at North Shields on the same date. Accused pleaded guilty. An officer from the prisoners? regiment said they were indifferent soldiers, because they had repeatedly absented themselves without leave. The officer knew nothing about the men?s records and said that was a matter that was not very carefully gone into at this time. The Chairman said he observed from the depositions taken at the police court that Jones said, ?We wanted money and clothes. I have soldiered for six months for a shilling. I got 90 days pay stopped.? The officer said it was true that Jones had lost a great deal of his pay but that was for absenting himself from his regiment. The balance of the account was on the other side. Jones, who was convicted of wilful damage at Dublin in May last, was sentenced to six months? imprisonment with hard labour on each charge, to run concurrently. Ingleson was sentenced to four months imprisonment with hard labour?. These images are taken from an album of photographs of prisoners brought before the North Shields Police Court between 1902 and 1916 (TWAM ref. DX1388/1). This set is our selection of the best mugshots taken during the First World War. They have been chosen because of the sharpness and general quality of the images. The album doesn?t record the details of each prisoner?s crimes, just their names and dates of arrest. In order to discover the stories behind the mugshots, staff from Tyne & Wear Archives & Museums visited North Shields Local Studies Library where they carefully searched through microfilm copies of the ?Shields Daily News? looking for newspaper reports of the court cases. The newspaper reports have been transcribed and added below each mugshot. Combining these two separate records gives us a fascinating insight into life on the Home Front during the First World War. These images document the lives of people of different ages and backgrounds, both civilians and soldiers. Our purpose here is not to judge them but simply to reflect the realities of their time. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

portrait | interesting | unusual | prisoner | crime | criminal | northshields | policestation | mugshot | arrested | soldier | firstworldwar | cap | imprisoned | theft | stealing | breakingandentering | earsdon | youngman | lovaineterrace | socialhistory | blackandwhitephotograph | criminalfacesofnorthshieldsfirstworldwar | johntingleson | northshieldspolicestation | 30march1915 | fascinating | theshieldsdailynews | 7april1915 | military | remand | 9lovaineterrace | steal | stolen | 16knives | cruet | clock | scissors | needles | silvertray | saltcellars | £37s6d | property | executors | latethomaswilliamson | uniform | confectionersshop | queenalexandraroad | twoloavesofbread | 7d | messrspattersonandreed | georgeanderson | detinsp | trial | quartersessions | pcdixon | chiefconstablehuish | watchcommittee | meritbadge | button | crease | blackborder | neutralbackground | grain | mark | standing | attentive | wrinkle | head | eye | mouth | nose | shoulderLicense

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See all metadataSide tank engine 'Earl of Mount Edgcumbe'

Description

An image of the side tank engine 'Earl of Mount Edgcumbe', one of two ordered by the Bere Alston & Calstock Railway in October 1906 (TWAM ref. DS.RSH/1/1/3). The railway was located in the South West of England. Engine nos. 2695-2696. Built for: Bere Alston & Calstock Railway. Date ordered 13 October 1906. Gauge of Railway: 4 feet 8½ inches. Principal Dimensions. Cylinders dia: 16 inches. Cylinders stroke: 24 inches. Wheels (Dia. of coupled): 4 feet 0 inch. Wheel-base - total: 16 feet 9 inches. Water capacity: 1360 gallons. Fuel capacity: 78 cubic feet = 1.75 tons. Heating surface ? total: 1016.7 square feet. Grate area: 16.8 square feet. Working pressure: 170 lbs per square inch. Total weight in working order: 49.85 tons. Tractive force taking 90% of the working pressure: 19584 lbs. Tractive force taking 75% of the working pressure: 16320 lbs. Approximate shipping space: 3725 cubic feet. Approximate gross weight packed for shipment: 43.25 tons. Code Word: EDGCUMBE This album celebrates the achievements of the Hawthorn Leslie locomotive works at Forth Banks, Newcastle upon Tyne. The works were established by Robert Hawthorn in January 1817 and in 1820 his brother, William Hawthorn joined him as a partner. The firm initially manufactured stationary engines but within a few years diversified into marine engineering and in 1831 produced its first locomotive engine for the Stockton and Darlington Railway. In 1870 the firm established a separate marine engine works on the River Tyne at St. Peter?s and from 1882 the Forth Banks Works became devoted entirely to the manufacture of locomotives. In 1885 the firm amalgamated with the shipyard of Andrew Leslie at Hebburn, creating the world-famous shipbuilding and engineering company R and W. Hawthorn, Leslie & Co. Ltd. The Forth Banks Works of Hawthorn Leslie produced engines of all types and sizes for railways around the world. The output of the Forth Banks Works included a large number of tank engines for industrial works and collieries and the firm established a speciality in the construction of crane locomotives. The images in this set date from the early twentieth century and are a reminder of Newcastle upon Tyne?s proud industrial heritage. They are taken from a series of photograph albums produced by Hawthorn Leslie. The albums were kindly donated to Tyne & Wear Archives by Alan C. Baker and T.D. Allen Civil. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.Subjects

train | locomotive | tankengine | industry | industrial | hawthornleslie | forthbanksworks | railways | newcastleupontyne | engineering | engines | interesting | historic | berealstoncalstockrailway | blackandwhitephotograph | sepiaphotograph | earlofmountedgcumbe | sidetankengine | october1906 | southwestofengland | unitedkingdom | digitalimage | unusual | fascinating | wheel | cog | parts | pipe | doorway | window | wall | roof | plate | bolt | cylinder | panel | signage | rail | transportation | industrialheritage | 13october1906 | hawthornleslielocomotives | forthbanks | roberthawthorn | williamhawthorn | partnership | locomotiveengine | manufacturingLicense

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One summer in the 1960s a young Japanese researcher, with the help of a few high school students, chopped up ten thousand jellyfish. As a by-product of this harvest, they isolated a green fluorescent protein (GFP). Since then, GFP has triggered a revolution in our understanding of gene expression and signaling in live cells. In this seminar, we will examine how this small protein generates fluorescence, i.e. absorbs light of one wavelength and emits light of a longer wavelength. We will discuss how the color palette has been extended from green to blue, red and many other colors, based on protein engineering of GFP and the study of vividly colorful coral reefs. We will then investigate how these fluorescent proteins can be used to track the motion of DNA, RNA and protein in living cells, a One summer in the 1960s a young Japanese researcher, with the help of a few high school students, chopped up ten thousand jellyfish. As a by-product of this harvest, they isolated a green fluorescent protein (GFP). Since then, GFP has triggered a revolution in our understanding of gene expression and signaling in live cells. In this seminar, we will examine how this small protein generates fluorescence, i.e. absorbs light of one wavelength and emits light of a longer wavelength. We will discuss how the color palette has been extended from green to blue, red and many other colors, based on protein engineering of GFP and the study of vividly colorful coral reefs. We will then investigate how these fluorescent proteins can be used to track the motion of DNA, RNA and protein in living cells, aSubjects

Green Fluorescent Protein | Green Fluorescent Protein | Fluorescent protein engineering | Fluorescent protein engineering | Photoconversion | Photoconversion | fluorescent protein variants | fluorescent protein variants | fluorescent microscopy facility | fluorescent microscopy facility | Quantitative fluorescent imaging | Quantitative fluorescent imaging | ultra-sensitive fluorescent imaging | ultra-sensitive fluorescent imaging | high-throughput analysis | high-throughput analysis | Fluorescent imaging in living organisms | Fluorescent imaging in living organisms | phycoerythrin | phycoerythrin | phytochrome | phytochrome | jellyfish | jellyfish | red fluorescent protein | red fluorescent protein | photoactivation | photoactivation | chromophore | chromophore | protonation | protonation | lysosomes | lysosomes | recombinant protein molecules | recombinant protein moleculesLicense

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from

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