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22.920 A Hands-On Introduction to Nuclear Magnetic Resonance (MIT) 22.920 A Hands-On Introduction to Nuclear Magnetic Resonance (MIT)

Description

Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging. Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging.

Subjects

nuclear spin | nuclear spin | magnetic resonance | magnetic resonance | rotating | rotating | otating frame | otating frame | rotating frame | rotating frame | RF pulses | RF pulses | Bloch's equations | Bloch's equations | magnetic field gradients | magnetic field gradients | k-space | k-space | diffusion | diffusion | spin echoes | spin echoes | NMR imaging in 2D | NMR imaging in 2D | slice selection | slice selection | flow studies | flow studies | NMR spectroscopy | NMR spectroscopy | chemical shifts | chemical shifts | spin-spin couplings | spin-spin couplings | Two dimensional NMR methods | Two dimensional NMR methods | COSY experiment | COSY experiment

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5.311 Introductory Chemical Experimentation (MIT) 5.311 Introductory Chemical Experimentation (MIT)

Description

5.311 is the first of a three-term laboratory subject sequence for chemistry majors. Experimental work emphasizes development of fundamental laboratory skills and techniques: volumetric and colorimetric analysis; nuclear magnetic resonance; preparation, purification, and characterization of chemical substances; and data analysis. Acknowledgements The experiments for 5.311 have evolved over a period of many years and include contributions from past instructors, course textbooks, and others affiliated with the course. Thus for many of the lab documents, no single source can be attributed. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individual 5.311 is the first of a three-term laboratory subject sequence for chemistry majors. Experimental work emphasizes development of fundamental laboratory skills and techniques: volumetric and colorimetric analysis; nuclear magnetic resonance; preparation, purification, and characterization of chemical substances; and data analysis. Acknowledgements The experiments for 5.311 have evolved over a period of many years and include contributions from past instructors, course textbooks, and others affiliated with the course. Thus for many of the lab documents, no single source can be attributed. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individual

Subjects

introductory chemistry lab | introductory chemistry lab | chemistry lab techniques | chemistry lab techniques | chemistry laboratory techniques | chemistry laboratory techniques | NMR | NMR | ferrocene | ferrocene | kinetics | kinetics | proton NMR | proton NMR | aromatic carboxylic acid | aromatic carboxylic acid | identifying unknown compounds | identifying unknown compounds | acetylferrocene | acetylferrocene | synthesis | synthesis | chromatography | chromatography | TLC | TLC | sublimation | sublimation

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5.32 Intermediate Chemical Experimentation (MIT) 5.32 Intermediate Chemical Experimentation (MIT)

Description

5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such 5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such

Subjects

intermediate chemical experimentation | intermediate chemical experimentation | experiment | experiment | chemistry | chemistry | organic synthesis | organic synthesis | chiral catalysis | chiral catalysis | purification | purification | organic chemistry | organic chemistry | laboratory | laboratory | IR | IR | 1D NMR | 1D NMR | 2D NMR | 2D NMR | UV spectroscopy | UV spectroscopy | mass spectrometry | mass spectrometry | thin layer gas chromatography | thin layer gas chromatography | non-chiral gas chromatography | non-chiral gas chromatography | chiral gas chromatography | chiral gas chromatography | enzyme purification | enzyme purification | characterization | characterization | assays | assays | molecular modeling | molecular modeling | biochemical systems | biochemical systems

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22.920 A Hands-On Introduction to Nuclear Magnetic Resonance (MIT)

Description

Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging.

Subjects

nuclear spin | magnetic resonance | rotating | otating frame | rotating frame | RF pulses | Bloch's equations | magnetic field gradients | k-space | diffusion | spin echoes | NMR imaging in 2D | slice selection | flow studies | NMR spectroscopy | chemical shifts | spin-spin couplings | Two dimensional NMR methods | COSY experiment

License

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5.46 Organic Structure Determination (MIT) 5.46 Organic Structure Determination (MIT)

Description

This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides. This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides.

Subjects

organic structure determination | organic structure determination | relative configuration | relative configuration | elemental analysis | elemental analysis | mass spectometry | mass spectometry | index of hydrogen deficiency | index of hydrogen deficiency | EA | EA | MS | MS | IHD | IHD | infrared spectroscopy | infrared spectroscopy | IR | IR | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | NMR | NMR | chemical equivalence | chemical equivalence | non-equivalence | non-equivalence | topicity | topicity | spin-spin splitting | spin-spin splitting | J coupling | J coupling | chemical shift | chemical shift

License

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3.A08 Attraction and Repulsion: The Magic of Magnets (MIT) 3.A08 Attraction and Repulsion: The Magic of Magnets (MIT)

Description

This Freshman Advising Seminar surveys the many applications of magnets and magnetism. To the Chinese and Greeks of ancient times, the attractive and repulsive forces between magnets must have seemed magical indeed. Through the ages, miraculous curative powers have been attributed to magnets, and magnets have been used by illusionists to produce "magical" effects. Magnets guided ships in the Age of Exploration and generated the electrical industry in the 19th century. Today they store information and entertainment on disks and tapes, and produce sound in speakers, images on TV screens, rotation in motors, and levitation in high-speed trains. Students visit various MIT projects related to magnets (including superconducting electromagnets) and read about and discuss the history, legends, p This Freshman Advising Seminar surveys the many applications of magnets and magnetism. To the Chinese and Greeks of ancient times, the attractive and repulsive forces between magnets must have seemed magical indeed. Through the ages, miraculous curative powers have been attributed to magnets, and magnets have been used by illusionists to produce "magical" effects. Magnets guided ships in the Age of Exploration and generated the electrical industry in the 19th century. Today they store information and entertainment on disks and tapes, and produce sound in speakers, images on TV screens, rotation in motors, and levitation in high-speed trains. Students visit various MIT projects related to magnets (including superconducting electromagnets) and read about and discuss the history, legends, p

Subjects

magnetism | magnetism | electromagnetic | electromagnetic | electromagnetism | electromagnetism | freshman seminar | freshman seminar | magnetic field | magnetic field | Mr. Magnet | Mr. Magnet | levitation | levitation | hard disk | hard disk | magnetoptic | magnetoptic | ferromagnetic | ferromagnetic | ferromagnetism | ferromagnetism | imaging | imaging | SQUID | SQUID | biomagnetism | biomagnetism | NMR | NMR

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22.058 Principles of Medical Imaging (MIT) 22.058 Principles of Medical Imaging (MIT)

Description

An introduction to the principles of tomographic imaging and its applications. It includes a series of lectures with a parallel set of recitations that provide demonstrations of basic principles. Both ionizing and non-ionizing radiation are covered, including x-ray, PET, MRI, and ultrasound. Emphasis on the physics and engineering of image formation. An introduction to the principles of tomographic imaging and its applications. It includes a series of lectures with a parallel set of recitations that provide demonstrations of basic principles. Both ionizing and non-ionizing radiation are covered, including x-ray, PET, MRI, and ultrasound. Emphasis on the physics and engineering of image formation.

Subjects

general imaging principles | | general imaging principles | | linear optics | | linear optics | | ray tracing | | ray tracing | | Linear Imaging Systems | | Linear Imaging Systems | | Space Invariance | | Space Invariance | | Pin-hole camera | | Pin-hole camera | | Fourier Transformations | | Fourier Transformations | | Modulation Transfer Functions | | Modulation Transfer Functions | | Fourier convolution | | Fourier convolution | | Sampling | | Sampling | | Nyquist | | Nyquist | | counting statistics | | counting statistics | | additive noise | | additive noise | | optical imaging | | optical imaging | | Radiation types | | Radiation types | | Radiation detection | | Radiation detection | | photon detection | | photon detection | | spectra | | spectra | | attenuation | | attenuation | | Planar X-ray imaging | | Planar X-ray imaging | | Projective Imaging | | Projective Imaging | | X-ray CT | | X-ray CT | | Ultrasound | | Ultrasound | | microscopy | k-space | | microscopy | k-space | | NMR pulses | | NMR pulses | | f2-D gradient | | f2-D gradient | | spin echoes | | spin echoes | | 3-D methods of MRI | | 3-D methods of MRI | | volume localized spectroscopy | volume localized spectroscopy

License

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5.35 Introduction to Experimental Chemistry (MIT) 5.35 Introduction to Experimental Chemistry (MIT)

Description

This course is the first part of a modular sequence of increasingly sophisticated (and challenging) laboratory courses required of all Chemistry majors: 5.35 Introduction to Experimental Chemistry, 5.36 Biochemistry and Organic Laboratory, 5.37 Organic and Inorganic Laboratory, and 5.38 Physical Chemistry Laboratory. This course provides students with a survey of spectroscopy, and introduces synthesis of coordination compounds and kinetics. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format.   AcknowledgementsProfessor Nelson and Dr. Twardowski would like to acknowledge the contribution This course is the first part of a modular sequence of increasingly sophisticated (and challenging) laboratory courses required of all Chemistry majors: 5.35 Introduction to Experimental Chemistry, 5.36 Biochemistry and Organic Laboratory, 5.37 Organic and Inorganic Laboratory, and 5.38 Physical Chemistry Laboratory. This course provides students with a survey of spectroscopy, and introduces synthesis of coordination compounds and kinetics. This class is part of the new laboratory curriculum in the MIT Department of Chemistry. Undergraduate Research-Inspired Experimental Chemistry Alternatives (URIECA) introduces students to cutting edge research topics in a modular format.   AcknowledgementsProfessor Nelson and Dr. Twardowski would like to acknowledge the contribution

Subjects

Chemistry | Chemistry | experimental chemistry | experimental chemistry | spectroscopy | spectroscopy | synthesis of coordination compounds and kinetics | synthesis of coordination compounds and kinetics | IR Spectroscopy | IR Spectroscopy | IR Spectroscopy of Proteins | IR Spectroscopy of Proteins | 15 MHz NMR | 15 MHz NMR | 300 MHz | 300 MHz | Lambert-Beer | Lambert-Beer | Kinetics Measurements | Kinetics Measurements

License

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5.46 Organic Structure Determination (MIT) 5.46 Organic Structure Determination (MIT)

Description

This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides. This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides.

Subjects

organic structure determination | organic structure determination | relative configuration | relative configuration | elemental analysis | elemental analysis | mass spectometry | mass spectometry | index of hydrogen deficiency | index of hydrogen deficiency | EA | EA | MS | MS | IHD | IHD | infrared spectroscopy | infrared spectroscopy | IR | IR | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | NMR | NMR | chemical equivalence | chemical equivalence | non-equivalence | non-equivalence | topicity | topicity | spin-spin splitting | spin-spin splitting | J coupling | J coupling | chemical shift | chemical shift

License

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5.73 Introductory Quantum Mechanics I (MIT) 5.73 Introductory Quantum Mechanics I (MIT)

Description

5.73 covers fundamental concepts of quantum mechanics: wave properties, uncertainty principles, Schrödinger equation, and operator and matrix methods. Basic applications of the following are discussed: one-dimensional potentials (harmonic oscillator), three-dimensional centrosymmetric potentials (hydrogen atom), and angular momentum and spin. The course also examines approximation methods: variational principle and perturbation theory. 5.73 covers fundamental concepts of quantum mechanics: wave properties, uncertainty principles, Schrödinger equation, and operator and matrix methods. Basic applications of the following are discussed: one-dimensional potentials (harmonic oscillator), three-dimensional centrosymmetric potentials (hydrogen atom), and angular momentum and spin. The course also examines approximation methods: variational principle and perturbation theory.

Subjects

quantum mechanics | quantum mechanics | NMR | NMR | kinetic isotope effects | kinetic isotope effects | hilbert space | hilbert space | eigenvalues | eigenvalues | particle in a box | particle in a box | harmonic oscillator | harmonic oscillator | perturbation theory | perturbation theory | angular momentum | angular momentum | Wigner-Eckart theorem | Wigner-Eckart theorem | hydrogen atom | hydrogen atom | spin-orbit interaction | spin-orbit interaction | Born Oppenheimer approximation | Born Oppenheimer approximation | Hartree-Fock | Hartree-Fock | Slater-Condon rules | Slater-Condon rules

License

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5.311 Introductory Chemical Experimentation (MIT)

Description

5.311 is the first of a three-term laboratory subject sequence for chemistry majors. Experimental work emphasizes development of fundamental laboratory skills and techniques: volumetric and colorimetric analysis; nuclear magnetic resonance; preparation, purification, and characterization of chemical substances; and data analysis. Acknowledgements The experiments for 5.311 have evolved over a period of many years and include contributions from past instructors, course textbooks, and others affiliated with the course. Thus for many of the lab documents, no single source can be attributed. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individual

Subjects

introductory chemistry lab | chemistry lab techniques | chemistry laboratory techniques | NMR | ferrocene | kinetics | proton NMR | aromatic carboxylic acid | identifying unknown compounds | acetylferrocene | synthesis | chromatography | TLC | sublimation

License

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5.05 Principles of Inorganic Chemistry III (MIT) 5.05 Principles of Inorganic Chemistry III (MIT)

Description

This course covers the principles of main group (s and p block) element chemistry with an emphasis on synthesis, structure, bonding, and reaction mechanisms. This course covers the principles of main group (s and p block) element chemistry with an emphasis on synthesis, structure, bonding, and reaction mechanisms.

Subjects

inorganic chemistry | inorganic chemistry | main group element chemistry | main group element chemistry | chemical synthesis | chemical synthesis | chemical structure | chemical structure | bonding | bonding | reaction mechanisms | reaction mechanisms | aluminum chemistry | aluminum chemistry | s block | s block | p block | p block | interatomic distance | interatomic distance | lewis structure | lewis structure | partitions space | partitions space | Density Functional Theory | Density Functional Theory | NMR spectroscopy | NMR spectroscopy | spin-orbit coupling | spin-orbit coupling | spin-spin coupling | spin-spin coupling | relativistic effects | relativistic effects | spin-orbit effects | spin-orbit effects | noble gas chemistry | noble gas chemistry | chemical reaction products | chemical reaction products

License

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5.13 Organic Chemistry II (MIT) 5.13 Organic Chemistry II (MIT)

Description

This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry. This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry.

Subjects

intermediate organic chemistry | intermediate organic chemistry | organic molecules | organic molecules | stereochemistry | stereochemistry | reaction mechanisms | reaction mechanisms | synthesis of organic compounds | synthesis of organic compounds | synthesis | synthesis | structure determination | structure determination | mechanism | mechanism | reactivity | reactivity | functional groups | functional groups | NMR | NMR | spectroscopy | spectroscopy | spectrometry | spectrometry | structure elucidation | structure elucidation | infrared spectroscopy | infrared spectroscopy | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | reactive intermediates | reactive intermediates | carbocations | carbocations | radicals | radicals | aromaticity | aromaticity | conjugated systems | conjugated systems | molecular orbital theory | molecular orbital theory | pericyclic reactions | pericyclic reactions

License

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5.32 Intermediate Chemical Experimentation (MIT)

Description

5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such

Subjects

intermediate chemical experimentation | experiment | chemistry | organic synthesis | chiral catalysis | purification | organic chemistry | laboratory | IR | 1D NMR | 2D NMR | UV spectroscopy | mass spectrometry | thin layer gas chromatography | non-chiral gas chromatography | chiral gas chromatography | enzyme purification | characterization | assays | molecular modeling | biochemical systems

License

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5.32 Intermediate Chemical Experimentation (MIT)

Description

5.32 involves more advanced experimental work than 5.310 or 5.311. The course emphasizes organic synthesis assisted by chiral catalysis, purification, and analysis of organic compounds employing such methods as IR, 1D and 2D NMR, UV spectroscopies and mass spectrometry, and thin layer and non-chiral and chiral gas chromatography. In 5.32, experiments also involve enzyme purification, characterization and assays, as well as molecular modeling in organic synthesis and in biochemical systems. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such

Subjects

intermediate chemical experimentation | experiment | chemistry | organic synthesis | chiral catalysis | purification | organic chemistry | laboratory | IR | 1D NMR | 2D NMR | UV spectroscopy | mass spectrometry | thin layer gas chromatography | non-chiral gas chromatography | chiral gas chromatography | enzyme purification | characterization | assays | molecular modeling | biochemical systems

License

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7.91J Foundations of Computational and Systems Biology (MIT) 7.91J Foundations of Computational and Systems Biology (MIT)

Description

This course is an introduction to computational biology emphasizing the fundamentals of nucleic acid and protein sequence and structural analysis; it also includes an introduction to the analysis of complex biological systems. Topics covered in the course include principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction and network modeling, as well as currently emerging research areas. This course is an introduction to computational biology emphasizing the fundamentals of nucleic acid and protein sequence and structural analysis; it also includes an introduction to the analysis of complex biological systems. Topics covered in the course include principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction and network modeling, as well as currently emerging research areas.

Subjects

7.91 | 7.91 | 20.490 | 20.490 | 20.390 | 20.390 | 7.36 | 7.36 | 6.802 | 6.802 | 6.874 | 6.874 | HST.506 | HST.506 | computational biology | computational biology | systems biology | systems biology | bioinformatics | bioinformatics | artificial intelligence | artificial intelligence | sequence analysis | sequence analysis | proteomics | proteomics | sequence alignment | sequence alignment | protein folding | protein folding | structure prediction | structure prediction | network modeling | network modeling | phylogenetics | phylogenetics | pairwise sequence comparisons | pairwise sequence comparisons | ncbi | ncbi | blast | blast | protein structure | protein structure | dynamic programming | dynamic programming | genome sequencing | genome sequencing | DNA | DNA | RNA | RNA | x-ray crystallography | x-ray crystallography | NMR | NMR | homologs | homologs | ab initio structure prediction | ab initio structure prediction | DNA microarrays | DNA microarrays | clustering | clustering | proteome | proteome | computational annotation | computational annotation

License

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5.301 Chemistry Laboratory Techniques (MIT) 5.301 Chemistry Laboratory Techniques (MIT)

Description

This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT. Acknowledgements The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, and Dr. Sarah A. Tabacco. WARNING NOTICE The experiments described in these materials a This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT. Acknowledgements The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, and Dr. Sarah A. Tabacco. WARNING NOTICE The experiments described in these materials a

Subjects

chemistry | chemistry | experiment | experiment | laboratory techniques | laboratory techniques | purification | purification | transfer and extraction | transfer and extraction | column chromatography | column chromatography | protein assays | protein assays | error analysis | error analysis | NMR | NMR | IR | IR | gas chromatography | gas chromatography | spectroscopy | spectroscopy | UV-Vis | UV-Vis | experimental chemistry | experimental chemistry | original research projects | original research projects

License

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5.61 Physical Chemistry (MIT) 5.61 Physical Chemistry (MIT)

Description

This course presents an introduction to quantum mechanics. It begins with an examination of the historical development of quantum theory, properties of particles and waves, wave mechanics and applications to simple systems—the particle in a box, the harmonic oscillator, the rigid rotor and the hydrogen atom. The lectures continue with a discussion of atomic structure and the Periodic Table. The final lectures cover applications to chemical bonding including valence bond and molecular orbital theory, molecular structure, and spectroscopy. Acknowledgements The material for 5.61 has evolved over a period of many years, and, accordingly, several faculty members have contributed to the development of the course contents. The original version of the lecture notes that are available on OCW This course presents an introduction to quantum mechanics. It begins with an examination of the historical development of quantum theory, properties of particles and waves, wave mechanics and applications to simple systems—the particle in a box, the harmonic oscillator, the rigid rotor and the hydrogen atom. The lectures continue with a discussion of atomic structure and the Periodic Table. The final lectures cover applications to chemical bonding including valence bond and molecular orbital theory, molecular structure, and spectroscopy. Acknowledgements The material for 5.61 has evolved over a period of many years, and, accordingly, several faculty members have contributed to the development of the course contents. The original version of the lecture notes that are available on OCW

Subjects

quantum mechanics | quantum mechanics | quantum chemistry | quantum chemistry | particles and waves | particles and waves | wave mechanics | wave mechanics | atomic structure | atomic structure | valence orbital | valence orbital | molecular orbital theory | molecular orbital theory | molecular structure | molecular structure | photochemistry | photochemistry | tunneling | tunneling | spherical harmonics | spherical harmonics | rigid rotor | rigid rotor | perturbation theory | perturbation theory | oscillators | oscillators | spectroscopy | spectroscopy | NMR | NMR | hartree-fock | hartree-fock | LCAO | LCAO

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7.91J Foundations of Computational and Systems Biology (MIT) 7.91J Foundations of Computational and Systems Biology (MIT)

Description

Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction, and network modeling are covered. Students are also exposed to currently emerging research areas in the fields of computational and systems biology. Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction, and network modeling are covered. Students are also exposed to currently emerging research areas in the fields of computational and systems biology.

Subjects

computational biology | computational biology | systems biology | systems biology | bioinformatics | bioinformatics | sequence analysis | sequence analysis | proteomics | proteomics | sequence alignment | sequence alignment | protein folding | protein folding | structure prediction | structure prediction | network modeling | network modeling | phylogenetics | phylogenetics | pairwise sequence comparisons | pairwise sequence comparisons | ncbi | ncbi | blast | blast | protein structure | protein structure | dynamic programming | dynamic programming | genome sequencing | genome sequencing | DNA | DNA | RNA | RNA | x-ray crystallography | x-ray crystallography | NMR | NMR | homologs | homologs | ab initio structure prediction | ab initio structure prediction | DNA microarrays | DNA microarrays | clustering | clustering | proteome | proteome | computational annotation | computational annotation | BE.490J | BE.490J | 7.91 | 7.91 | 7.36 | 7.36 | BE.490 | BE.490 | 20.490 | 20.490

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5.301 Chemistry Laboratory Techniques (MIT) 5.301 Chemistry Laboratory Techniques (MIT)

Description

This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT. Acknowledgements The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, Dr. Sarah A. Tabacco, Dr. Kimberly L. Berkowski, Anne M. (Gorham) Rachupka, and Dr. Joh This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT. Acknowledgements The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, Dr. Sarah A. Tabacco, Dr. Kimberly L. Berkowski, Anne M. (Gorham) Rachupka, and Dr. Joh

Subjects

chemistry | chemistry | experiment | experiment | laboratory techniques | laboratory techniques | purification | purification | transfer and extraction | transfer and extraction | column chromatography | column chromatography | protein assays | protein assays | error analysis | error analysis | NMR | NMR | IR | IR | gas chromatography | gas chromatography | spectroscopy | spectroscopy | UV-Vis | UV-Vis

License

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5.301 Chemistry Laboratory Techniques (MIT)

Description

This course is an intensive introduction to the techniques of experimental chemistry and gives first year students an opportunity to learn and master the basic chemistry lab techniques for carrying out experiments. Students who successfully complete the course and obtain a "Competent Chemist" (CC) or "Expert Experimentalist" (EE) rating are likely to secure opportunities for research work in a chemistry lab at MIT. Acknowledgements The laboratory manual and materials for this course were prepared by Dr. Katherine J. Franz and Dr. Kevin M. Shea with the assistance of Professors Rick L. Danheiser and Timothy M. Swager. Materials have been revised by Dr. J. Haseltine, Dr. Kevin M. Shea, and Dr. Sarah A. Tabacco. WARNING NOTICE The experiments described in these materials a

Subjects

chemistry | experiment | laboratory techniques | purification | transfer and extraction | column chromatography | protein assays | error analysis | NMR | IR | gas chromatography | spectroscopy | UV-Vis | experimental chemistry | original research projects

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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7.91J Foundations of Computational and Systems Biology (MIT)

Description

Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction, and network modeling are covered. Students are also exposed to currently emerging research areas in the fields of computational and systems biology.

Subjects

computational biology | systems biology | bioinformatics | sequence analysis | proteomics | sequence alignment | protein folding | structure prediction | network modeling | phylogenetics | pairwise sequence comparisons | ncbi | blast | protein structure | dynamic programming | genome sequencing | DNA | RNA | x-ray crystallography | NMR | homologs | ab initio structure prediction | DNA microarrays | clustering | proteome | computational annotation | BE.490J | 7.91 | 7.36 | BE.490 | 20.490

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.91J Foundations of Computational and Systems Biology (MIT)

Description

Serving as an introduction to computational biology, this course emphasizes the fundamentals of nucleic acid and protein sequence analysis, structural analysis, and the analysis of complex biological systems. The principles and methods used for sequence alignment, motif finding, structural modeling, structure prediction, and network modeling are covered. Students are also exposed to currently emerging research areas in the fields of computational and systems biology.

Subjects

computational biology | systems biology | bioinformatics | sequence analysis | proteomics | sequence alignment | protein folding | structure prediction | network modeling | phylogenetics | pairwise sequence comparisons | ncbi | blast | protein structure | dynamic programming | genome sequencing | DNA | RNA | x-ray crystallography | NMR | homologs | ab initio structure prediction | DNA microarrays | clustering | proteome | computational annotation | BE.490J | 7.91 | 7.36 | BE.490 | 20.490

License

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3.A08 Attraction and Repulsion: The Magic of Magnets (MIT)

Description

This Freshman Advising Seminar surveys the many applications of magnets and magnetism. To the Chinese and Greeks of ancient times, the attractive and repulsive forces between magnets must have seemed magical indeed. Through the ages, miraculous curative powers have been attributed to magnets, and magnets have been used by illusionists to produce "magical" effects. Magnets guided ships in the Age of Exploration and generated the electrical industry in the 19th century. Today they store information and entertainment on disks and tapes, and produce sound in speakers, images on TV screens, rotation in motors, and levitation in high-speed trains. Students visit various MIT projects related to magnets (including superconducting electromagnets) and read about and discuss the history, legends, p

Subjects

magnetism | electromagnetic | electromagnetism | freshman seminar | magnetic field | Mr. Magnet | levitation | hard disk | magnetoptic | ferromagnetic | ferromagnetism | imaging | SQUID | biomagnetism | NMR

License

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5.13 Organic Chemistry II (MIT)

Description

This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry.

Subjects

intermediate organic chemistry | organic molecules | stereochemistry | reaction mechanisms | synthesis of organic compounds | synthesis | structure determination | mechanism | reactivity | functional groups | NMR | spectroscopy | spectrometry | structure elucidation | infrared spectroscopy | nuclear magnetic resonance spectroscopy | reactive intermediates | carbocations | radicals | aromaticity | conjugated systems | molecular orbital theory | pericyclic reactions

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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