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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | BE.370 | BE.370 | BE.470 | BE.470 | HST.541 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | equilibrium potential | equilibrium potential | resting potential | resting potential | action potential | action potential | voltage-gated ion channels | voltage-gated ion channels | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | 20.370 | 20.370 | 20.470 | 20.470 | HST.541 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Concentration Gradients

Description

This RLO describes the concept of concentration gradients in biological systems through analogy with gradients found in everyday life, and outlines passive and active transport across cell membranes.

Subjects

concentration gradient | cell membrane | active transport | passive transport | osmosis | foundation science | Physical Sciences | Biological Sciences | Biological sciences | Physical sciences | C000 | F000

License

Attribution-Share Alike 2.0 UK: England & Wales Attribution-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-sa/2.0/uk/ http://creativecommons.org/licenses/by-sa/2.0/uk/

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6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f

Subjects

quantitative physiology | cells | tissues | mass transport | electrical signal generation | biological membranes | membranes | diffusion | osmosis | chemically mediated transport | active transport | ion transport | 6.021 | 2.791 | 2.794 | 6.521 | BE.370 | BE.470 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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https://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

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6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i

Subjects

quantitative physiology | cells | tissues | mass transport | electrical signal generation | biological membranes | membranes | diffusion | osmosis | chemically mediated transport | active transport | ion transport | equilibrium potential | resting potential | action potential | voltage-gated ion channels | 6.021 | 2.791 | 2.794 | 6.521 | 20.370 | 20.470 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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https://ocw.mit.edu/rss/all/mit-allcourses.xml

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