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Streptomyces in Nature and Medicine: The Antibiotic Makers

Description

Although plants are a very important part of a garden, we must not forget about the important contribution that soil makes. Bacteria living in the soil also produce compounds important as modern antibiotics. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

botany | streptomyces | gardening | soil | antibiotics | Health | botanic gardens | Medicine | botany | streptomyces | gardening | soil | antibiotics | Health | botanic gardens | Medicine | 2010-10-18

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7.342 Chronic Infection and Inflammation: What are the Consequences on Your Health? (MIT) 7.342 Chronic Infection and Inflammation: What are the Consequences on Your Health? (MIT)

Description

In this course we will explore the new emerging field of pathogen-induced chronic diseases. Work in this field has redefined the causes of some major disorders, such as ulcers. By reading the primary research literature we will learn about the molecular mechanisms through which pathogens cause disease. The diseases that we cover will be introduced with a short patient case study. We will discuss the bacterium Helicobacter pylori and gastric disease, HPV and cervical cancer, hepatitis C virus and liver disease, Epstein-Barr virus and lymphoma, Cytomegalovirus and atherosclerosis, as well as diabetes and multiple sclerosis. We will study technical advances in the fight against microbes and explore future directions for new treatment strategies of chronic infections and inflammation. This cou In this course we will explore the new emerging field of pathogen-induced chronic diseases. Work in this field has redefined the causes of some major disorders, such as ulcers. By reading the primary research literature we will learn about the molecular mechanisms through which pathogens cause disease. The diseases that we cover will be introduced with a short patient case study. We will discuss the bacterium Helicobacter pylori and gastric disease, HPV and cervical cancer, hepatitis C virus and liver disease, Epstein-Barr virus and lymphoma, Cytomegalovirus and atherosclerosis, as well as diabetes and multiple sclerosis. We will study technical advances in the fight against microbes and explore future directions for new treatment strategies of chronic infections and inflammation. This cou

Subjects

Seminar | Seminar | literature review | literature review | cancer | cancer | vaccine | vaccine | antibiotic | antibiotic | chronic | chronic | atherosclerosis | atherosclerosis | diabetes | diabetes | human papilloma virus | human papilloma virus | HPV | HPV | helicobacter pylori | helicobacter pylori | epstein-barr | epstein-barr | treatment strategies | treatment strategies | laboratory techniques | laboratory techniques | lab | lab | herpes | herpes | microbes | microbes | infection | infection | health | health | Epstein-Barr | Epstein-Barr | cervical cancer | cervical cancer | cirrhosis | cirrhosis | multiple sclerosis | multiple sclerosis | hepatitis | hepatitis | hepatocellular carcinoma | hepatocellular carcinoma | gastric | gastric

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.345 The War on Superbugs: Antibiotic Development and the Emergence of Drug-Resistant Bacteria (MIT) 7.345 The War on Superbugs: Antibiotic Development and the Emergence of Drug-Resistant Bacteria (MIT)

Description

Bacteria and fungi have produced antibiotics, small molecules that can prevent the growth of or kill bacteria by inhibiting essential biological pathways, as a defense mechanism long before humans walked the earth. The discovery of antibiotics and their implementation in the clinic radically changed modern medicine, saving countless lives by treating infections that were once difficult to cure, such as syphilis, strep throat and tuberculosis. During this course, we will cover many aspects of antibiotics including techniques used to discover these inhibitors, their mode of action and use in medicine. For example, we will learn about the techniques used to discover antibiotics, such as penicillin and vancomycin. We will discuss antibiotic-resistant bacteria and the molecular mechanisms under Bacteria and fungi have produced antibiotics, small molecules that can prevent the growth of or kill bacteria by inhibiting essential biological pathways, as a defense mechanism long before humans walked the earth. The discovery of antibiotics and their implementation in the clinic radically changed modern medicine, saving countless lives by treating infections that were once difficult to cure, such as syphilis, strep throat and tuberculosis. During this course, we will cover many aspects of antibiotics including techniques used to discover these inhibitors, their mode of action and use in medicine. For example, we will learn about the techniques used to discover antibiotics, such as penicillin and vancomycin. We will discuss antibiotic-resistant bacteria and the molecular mechanisms under

Subjects

superbugs | superbugs | antibiotics | antibiotics | drug-resistance | drug-resistance | bacteria | bacteria | infection | infection | penicillin | penicillin | drug discovery | drug discovery | vancomycin | vancomycin

License

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Biomaths Tutor

Description

Haemocytometer volume and cell count calculations

Subjects

cells | anaemia | data interpretation | microbiology | calculations | antibiotic concentrations antibiotic bioassays | Biological sciences | C000

License

Attribution-Noncommercial 2.0 UK: England & Wales Attribution-Noncommercial 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc/2.0/uk/ http://creativecommons.org/licenses/by-nc/2.0/uk/

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20.201 Mechanisms of Drug Actions (MIT) 20.201 Mechanisms of Drug Actions (MIT)

Description

This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets. This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.

Subjects

drugs | drugs | medicine | medicine | pharmaceutical | pharmaceutical | pharmacology | pharmacology | toxicology | toxicology | drug actions | drug actions | therapeutics | therapeutics | histology | histology | pathophysiology | pathophysiology | drug therapy | drug therapy | drug transporters | drug transporters | drug metabolism | drug metabolism | drug toxicity | drug toxicity | drug development | drug development | uptake | uptake | transport | transport | case study | case study | biochemistry | biochemistry | Pharmacokinetics | Pharmacokinetics | Pharmacogenetics | Pharmacogenetics | Omeprazole | Omeprazole | antibiotics | antibiotics | Oncology | Oncology | Statins | Statins | Sarilumab | Sarilumab | cystic fibrosis | cystic fibrosis

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.016 Introductory Biology (MIT) 7.016 Introductory Biology (MIT)

Description

7.016 Introductory Biology provides an introduction to fundamental principles of biochemistry, molecular biology and genetics for understanding the functions of living systems. Taught for the first time in Fall 2013, this course covers examples of the use of chemical biology and twenty-first-century molecular genetics in understanding human health and therapeutic intervention. The MIT Biology Department Introductory Biology courses, 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as the structure and synthesis of proteins, how these mol 7.016 Introductory Biology provides an introduction to fundamental principles of biochemistry, molecular biology and genetics for understanding the functions of living systems. Taught for the first time in Fall 2013, this course covers examples of the use of chemical biology and twenty-first-century molecular genetics in understanding human health and therapeutic intervention. The MIT Biology Department Introductory Biology courses, 7.012, 7.013, 7.014, 7.015, and 7.016 all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as the structure and synthesis of proteins, how these mol

Subjects

biochemistry | biochemistry | molecular biology | molecular biology | genetics | genetics | human genetics | human genetics | pedigrees | pedigrees | biochemical genetics | biochemical genetics | chemical biology | chemical biology | molecular genetics | molecular genetics | recombinant DNA technology | recombinant DNA technology | cell biology | cell biology | cancer | cancer | viruses | viruses | HIV | HIV | bacteria | bacteria | antibiotics | antibiotics | human health | human health | therapeutic intervention | therapeutic intervention | cell signaling | cell signaling | evolution | evolution | reproduction | reproduction | infectious diseases | infectious diseases | therapeutics | therapeutics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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RJN0001MI0019

Description

Milk testing with Beta Star test.

Subjects

milk | antibiotics | testing | residues | antibioticsresidues | betastar

License

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Modelling bacterial drug resistance

Description

Professor Ben Cooper from MORU in Thailand uses mathematical modelling and statistical techniques to help understand the dynamics of infectious disease and evaluate potential control measures. Antibiotic resistance is one of today's major global health problems. Mathematical models help us answer what if questions and evaluate the impact of specific interventions such as hands hygiene on the spread of bacterial drug resistance. Effective solutions are then translated into policy changes or changes in practice at national or international level. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

antibiotic resistance | mathematical modelling | infectious diseases | antibiotic resistance | mathematical modelling | infectious diseases

License

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RJN0001MI0019

Description

Milk testing with Beta Star test.

Subjects

milk | antibiotics | testing | residues | antibioticsresidues | betastar

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B0000P0039

Description

A bottle of Conveia, Active ingredient Cefovecin sodium

Subjects

svmsvet | drug | drugs | injectable | antibiotic | convenia | cefovecinsodium | cefovacin | cephalosporin | longactingantibiotic | longactingcephalosporin | pfizer

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B0000P0039

Description

A bottle of Conveia, Active ingredient Cefovecin sodium

Subjects

svmsvet | drug | drugs | injectable | antibiotic | convenia | cefovecinsodium | cefovacin | cephalosporin | longactingantibiotic | longactingcephalosporin | pfizer

License

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Antibiotics Workshop

Description

The aim of this session is to provide a basic introduction to the prescribing of antibiotics as part of the independent and supplementary prescribing programme. It is aimed to provide an overview of the use of antibiotics, with emphasis on the safe use of these agents, and considering the underlying principles of choice, ethics, accountability and the consideration of antibiotic resistance. It is aimed for students for practitioners with basic knowledge and/or experience in this area of practice.

Subjects

independant-supplementary-prescribing | prescribing | antibiotics | antimicrobials | antibiotic resistance | supplementary prescribing | independent prescribing | ethics | accountability | interprofessional | ukoer | tigeroer | Subjects allied to medicine | B000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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A0000P0002

Description

A bottle of Convenia.

Subjects

svmsvet | drug | drugs | injectable | injectabledrug | injectabledrugs | antibiotic | convenia | cefovecin | cephalosporin | injectablecephalosporin | longactingantibiotic | longactingcephalosporin

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Computation and genetics

Description

Resistance to drugs in bacteria can be aquired by swapping genes between individual bacteria. Computer programs developed by Dr Iqbal enable doctors to predict which antibiotics will be met with drug resistance, enabling the selection of the right drug. BIOINFORMATICS & PATHOGEN GENOMICS Dr Zamin Iqbal studies the DNA of bacteria and parasites, and compares the genomes of individual pathogens to track the spread of antibiotic resistance. Pathogens accumulate small genetic changes over time, and by tracking these changes, it is possible to map the spread of an infection. This enables better surveillance of pathogen evolution, within a host, within a hospital and across the world. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

computational | genetics | bioinformatics | pathogens | drug resistance | DNA | antibiotic resistance | computational | genetics | bioinformatics | pathogens | drug resistance | DNA | antibiotic resistance

License

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A0000P0002

Description

A bottle of Convenia.

Subjects

svmsvet | drug | drugs | injectable | injectabledrug | injectabledrugs | antibiotic | convenia | cefovecin | cephalosporin | injectablecephalosporin | longactingantibiotic | longactingcephalosporin

License

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7.341 Harnessing the Biosphere: Natural Products and Biotechnology (MIT) 7.341 Harnessing the Biosphere: Natural Products and Biotechnology (MIT)

Description

What do the organisms of the biosphere, specifically microorganisms, have to offer to biotechnological endeavors? In this course we will focus on the production of biomolecules using microbial systems. We will discuss potential growth substrates (such as agricultural waste and carbon dioxide) that can be used and learn about both established and cutting-edge manipulation techniques in the field of synthetic biology. We will also cover the production of biofuels, bioplastics, amino acids (e.g. lysine), food additives (e.g. monosodium glutamate, MSG), specialty chemicals (e.g. succinate), and biopharmaceuticals (e.g. plasmids for gene therapy). This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an What do the organisms of the biosphere, specifically microorganisms, have to offer to biotechnological endeavors? In this course we will focus on the production of biomolecules using microbial systems. We will discuss potential growth substrates (such as agricultural waste and carbon dioxide) that can be used and learn about both established and cutting-edge manipulation techniques in the field of synthetic biology. We will also cover the production of biofuels, bioplastics, amino acids (e.g. lysine), food additives (e.g. monosodium glutamate, MSG), specialty chemicals (e.g. succinate), and biopharmaceuticals (e.g. plasmids for gene therapy). This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an

Subjects

microorganisms | microorganisms | biomolecules | biomolecules | microbial systems | microbial systems | synthetic biology | synthetic biology | biofuels | biofuels | bioplastics | bioplastics | amino acids | amino acids | lysine | lysine | food additives | food additives | monosodium glutamate (MSG) | monosodium glutamate (MSG) | specialty chemicals | specialty chemicals | succinate | succinate | biopharmaceuticals | biopharmaceuticals | enzymes | enzymes | antibiotics and biocompatible materials | antibiotics and biocompatible materials | microbial biotechnology | microbial biotechnology | genetic engineering | genetic engineering

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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E0000P0112

Description

A box of Excenel. Contents as a powder

Subjects

svmsvet | large | antibiotic | ceftiofur | injectable | 3rd | generation | cephalosporin | excenel

License

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E0000P0118

Description

Cans of Cyclo spray

Subjects

svmsvet | cyclo | spray | chlortetracycline | tetracycline | antibiotic | farm

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C0000P0059

Description

Subjects

svmsvet | drugs | antibiotic | enrofloxacin | baytril | antimicrobial | 25solution | oral

License

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C0000P0069

Description

Subjects

svmsvet | drugs | antibiotic | cephalexin | ceporex | cephalosporin | tablet | antimicrobial

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C0000P0055

Description

Subjects

svmsvet | drugs | antibiotic | penicillin | augmentin | amoxicillin | injectable | betalactam

License

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C0000P0067

Description

Subjects

svmsvet | drugs | antibiotic

License

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C0000P0051

Description

Subjects

svmsvet | drugs | antibiotic | clindamycin | antirobe | capsules | capsule | pfizer | lincosamide

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C0000P0049

Description

Subjects

svmsvet | drugs | drug | topical | aurizon | ear | eardrops | antimicrobial | marbofloxacin | antibiotic | antifungal | steroid | antiinflammatory | dexamethasone | clotrimazole

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C0000P0059

Description

Subjects

svmsvet | drugs | antibiotic | enrofloxacin | baytril | antimicrobial | 25solution | oral

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