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20.462J Molecular Principles of Biomaterials (MIT) 20.462J Molecular Principles of Biomaterials (MIT)

Description

This course covers the analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, vaccines, and cell-guiding surfaces. This course covers the analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, vaccines, and cell-guiding surfaces.

Subjects

biomaterials | biomaterials | biomaterial engineering | biomaterial engineering | biotechnology | biotechnology | cell-guiding surface | cell-guiding surface | molecular biomaterials | molecular biomaterials | drug release | drug release | polymers | polymers | pulsatile release | pulsatile release | polymerization | polymerization | polyer erosion | polyer erosion | tissue engineering | tissue engineering | hydrogels | hydrogels | adhesion | adhesion | migration | migration | drug diffusion | drug diffusion | molecular switches | molecular switches | molecular motors | molecular motors | nanoparticles | nanoparticles | microparticles | microparticles | vaccines | vaccines | drug targeting | drug targeting | micro carriers | micro carriers | nano carriers | nano carriers | intracellular drug delivery | intracellular drug delivery | 20.462 | 20.462 | 3.962 | 3.962

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View of 'Naess Crusader' from across the River Wear View of 'Naess Crusader' from across the River Wear

Description

Subjects

roof | roof | sky | sky | cloud | cloud | abstract | abstract | building | building | industry | industry | window | window | water | water | wall | wall | daylight | daylight | interesting | interesting | construction | construction | marine | marine | industrial | industrial | ship | ship | unitedkingdom | unitedkingdom | crane | crane | platform | platform | bank | bank | rail | rail | vessel | vessel | rope | rope | structure | structure | historic | historic | riverwear | riverwear | beam | beam | cranes | cranes | deck | deck | walkway | walkway | bow | bow | land | land | unusual | unusual | shipyard | shipyard | shipping | shipping | majestic | majestic | stern | stern | development | development | carrier | carrier | fascinating | fascinating | digitalimage | digitalimage | sunderland | sunderland | landcape | landcape | shipbuilding | shipbuilding | industrialheritage | industrialheritage | wearside | wearside | northeastengland | northeastengland | blackandwhitephotograph | blackandwhitephotograph | northeastofengland | northeastofengland | shipbuildingheritage | shipbuildingheritage | maritimeheritage | maritimeheritage | obocarrier | obocarrier | northsandsshipyard | northsandsshipyard | oilbulkore | oilbulkore | sunderlandshipbuildersltd | sunderlandshipbuildersltd | northsandssunderland | northsandssunderland | naesscrusader | naesscrusader | turnersphotographyltd | turnersphotographyltd | 14august1972 | 14august1972 | sunderlandkeelline | sunderlandkeelline | naesscrusadersunderlandslargestship | naesscrusadersunderlandslargestship | angloeasternbulkshipsltd | angloeasternbulkshipsltd

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Painting the bow of 'Naess Crusader' Painting the bow of 'Naess Crusader'

Description

Subjects

sky | sky | people | people | cloud | cloud | abstract | abstract | blur | blur | industry | industry | buildings | buildings | river | river | painting | painting | daylight | daylight | interesting | interesting | wire | wire | workers | workers | construction | construction | industrial | industrial | scaffolding | scaffolding | ship | ship | unitedkingdom | unitedkingdom | crane | crane | painted | painted | debris | debris | grain | grain | platform | platform | bank | bank | rail | rail | vessel | vessel | rope | rope | calm | calm | structure | structure | historic | historic | riverwear | riverwear | cranes | cranes | deck | deck | pile | pile | maritime | maritime | bow | bow | porthole | porthole | unusual | unusual | launch | launch | shipyard | shipyard | passage | passage | shipping | shipping | majestic | majestic | plank | plank | carrier | carrier | newcastleupontyne | newcastleupontyne | fascinating | fascinating | digitalimage | digitalimage | sunderland | sunderland | observing | observing | shipbuilding | shipbuilding | industrialheritage | industrialheritage | 2015 | 2015 | wearside | wearside | northeastengland | northeastengland | blackandwhitephotograph | blackandwhitephotograph | shipbuildingheritage | shipbuildingheritage | maritimeheritage | maritimeheritage | december1972 | december1972 | keelline | keelline | obocarrier | obocarrier | northsandsshipyard | northsandsshipyard | sunderlandshipbuildersltd | sunderlandshipbuildersltd | northsandssunderland | northsandssunderland | nordicchieftain | nordicchieftain | naesscrusader | naesscrusader | turnersphotographyltd | turnersphotographyltd | sunderlandkeelline | sunderlandkeelline | 2917metreslong | 2917metreslong | naesscrusadersunderlandslargestship | naesscrusadersunderlandslargestship | angloeasternbulkshipsltd | angloeasternbulkshipsltd | obooilbulkore | obooilbulkore | largestships | largestships

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Deck view of 'Naess Crusader' at the fitting out quay Deck view of 'Naess Crusader' at the fitting out quay

Description

Subjects

bridge | bridge | roof | roof | chimney | chimney | sky | sky | abstract | abstract | industry | industry | window | window | glass | glass | wall | wall | buildings | buildings | river | river | vent | vent | interesting | interesting | dock | dock | construction | construction | cabin | cabin | stair | stair | industrial | industrial | ship | ship | mechanical | mechanical | unitedkingdom | unitedkingdom | crane | crane | timber | timber | parts | parts | debris | debris | bridges | bridges | machine | machine | bank | bank | rail | rail | plate | plate | vessel | vessel | rope | rope | tools | tools | structure | structure | historic | historic | stages | stages | riverwear | riverwear | foundation | foundation | cranes | cranes | chain | chain | pile | pile | cylinder | cylinder | oil | oil | unusual | unusual | shipyard | shipyard | shipping | shipping | ore | ore | development | development | carrier | carrier | fascinating | fascinating | digitalimage | digitalimage | sunderland | sunderland | bulk | bulk | shipbuilding | shipbuilding | industrialheritage | industrialheritage | 2015 | 2015 | wearside | wearside | northeastengland | northeastengland | blackandwhitephotograph | blackandwhitephotograph | shipbuildingheritage | shipbuildingheritage | maritimeheritage | maritimeheritage | manorquay | manorquay | largestship | largestship | obocarrier | obocarrier | sunderlandshipbuildersltd | sunderlandshipbuildersltd | northsandssunderland | northsandssunderland | nordicchieftain | nordicchieftain | naesscrusader | naesscrusader | fittingoutquay | fittingoutquay | turnersphotographyltd | turnersphotographyltd | sunderlandkeelline | sunderlandkeelline | 2917metreslong | 2917metreslong | 29january1973 | 29january1973 | naesscrusadersunderlandslargestship | naesscrusadersunderlandslargestship | angloeasternbulkshipsltd | angloeasternbulkshipsltd

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On the bridge of 'Naess Crusader' On the bridge of 'Naess Crusader'

Description

Subjects

door | door | bridge | bridge | light | light | abstract | abstract | reflection | reflection | industry | industry | window | window | glass | glass | wall | wall | river | river | screw | screw | handle | handle | switch | switch | daylight | daylight | interesting | interesting | construction | construction | cabin | cabin | industrial | industrial | ship | ship | floor | floor | unitedkingdom | unitedkingdom | letters | letters | pipe | pipe | surreal | surreal | plate | plate | vessel | vessel | tools | tools | structure | structure | ceiling | ceiling | historic | historic | riverwear | riverwear | deck | deck | cardboard | cardboard | maritime | maritime | controls | controls | cylinder | cylinder | unusual | unusual | launch | launch | shipyard | shipyard | shipping | shipping | development | development | carrier | carrier | digitalimage | digitalimage | sunderland | sunderland | shipbuilding | shipbuilding | industrialheritage | industrialheritage | 2015 | 2015 | wearside | wearside | northeastengland | northeastengland | blackandwhitephotograph | blackandwhitephotograph | seatrials | seatrials | shipbuildingheritage | shipbuildingheritage | maritimeheritage | maritimeheritage | shipinterior | shipinterior | largestship | largestship | obocarrier | obocarrier | northsandsshipyard | northsandsshipyard | oilbulkore | oilbulkore | sunderlandshipbuildersltd | sunderlandshipbuildersltd | northsandssunderland | northsandssunderland | nordicchieftain | nordicchieftain | naesscrusader | naesscrusader | turnersphotographyltd | turnersphotographyltd | 4june1973 | 4june1973 | sunderlandkeelline | sunderlandkeelline | 2917metreslong | 2917metreslong | naesscrusadersunderlandslargestship | naesscrusadersunderlandslargestship | angloeasternbulkshipsltd | angloeasternbulkshipsltd

License

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HMS Ark Royal - Leaving the Tyne for the first time on trials 19th October 1984

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-123 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | colourphotograph | digitalimage | vessel | maritimeheritage | industry | industrialheritage | shipbuildingheritage | abstract | flag | rail | deck | cabin | transportation | crew | navalhistory | leavingthetyneriver | trials | 19thoctober1984 | formerflagship | classaircraftcarrier | themightyark | keel | swanhunter | 7thdecember1978 | 20thjune1981 | launch | majordeployments | bosnianwar | conflict | invasionofiraq | 2010volcaniceruption | swanhuntercollection | engaging | unusual | northeastofengland | unitedkingdom

License

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2.57 Nano-to-Macro Transport Processes (MIT) 2.57 Nano-to-Macro Transport Processes (MIT)

Description

This course provides parallel treatments of photons, electrons, phonons, and molecules as energy carriers, aiming at fundamental understanding and descriptive tools for energy and heat transport processes from nanoscale continuously to macroscale. Topics include the energy levels, the statistical behavior and internal energy, energy transport in the forms of waves and particles, scattering and heat generation processes, Boltzmann equation and derivation of classical laws, deviation from classical laws at nanoscale and their appropriate descriptions, with applications in nano- and microtechnology. This course provides parallel treatments of photons, electrons, phonons, and molecules as energy carriers, aiming at fundamental understanding and descriptive tools for energy and heat transport processes from nanoscale continuously to macroscale. Topics include the energy levels, the statistical behavior and internal energy, energy transport in the forms of waves and particles, scattering and heat generation processes, Boltzmann equation and derivation of classical laws, deviation from classical laws at nanoscale and their appropriate descriptions, with applications in nano- and microtechnology.

Subjects

nanotechnology | nanotechnology | nanoscale | nanoscale | transport phenomena | transport phenomena | photons | photons | electrons | electrons | phonons | phonons | energy carriers | energy carriers | energy transport | energy transport | heat transport | heat transport | energy levels | energy levels | statistical behavior | statistical behavior | internal energy | internal energy | waves and particles | waves and particles | scattering | scattering | heat generation | heat generation | Boltzmann equation | Boltzmann equation | classical laws | classical laws | microtechnology | microtechnology | crystal | crystal | lattice | lattice | quantum oscillator | quantum oscillator | laudaurer | laudaurer | nanotube | nanotube | Louiville equation | Louiville equation | X-ray | X-ray | blackbody | blackbody | quantum well | quantum well | Fourier | Fourier | Newton | Newton | Ohm | Ohm | thermoelectric effect | thermoelectric effect | Brownian motion | Brownian motion | surface tension | surface tension | van der Waals potential. | van der Waals potential. | van der Waals potential | van der Waals potential

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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12.540 Principles of the Global Positioning System (MIT) 12.540 Principles of the Global Positioning System (MIT)

Description

The aim of this course is to introduce the principles of the Global Positioning System and to demonstrate its application to various aspects of Earth Sciences. The specific content of the course depends each year on the interests of the students in the class. In some cases, the class interests are towards the geophysical applications of GPS and we concentrate on high precision(millimeter level) positioning on regional and global scales. In other cases, the interests have been more toward engineering applications of kinematic positioning with GPS in which case the concentration is on positioning with slightly less accuracy but being able to do so for a moving object. In all cases, we concentrate on the fundamen The aim of this course is to introduce the principles of the Global Positioning System and to demonstrate its application to various aspects of Earth Sciences. The specific content of the course depends each year on the interests of the students in the class. In some cases, the class interests are towards the geophysical applications of GPS and we concentrate on high precision(millimeter level) positioning on regional and global scales. In other cases, the interests have been more toward engineering applications of kinematic positioning with GPS in which case the concentration is on positioning with slightly less accuracy but being able to do so for a moving object. In all cases, we concentrate on the fundamen

Subjects

Global Positioning System | Global Positioning System | Earth Sciences | Earth Sciences | geophysical applications | geophysical applications | GPS | GPS | engineering applications | engineering applications | kinematic positioning | kinematic positioning | precision | precision | accuracy | accuracy | moving objects | moving objects | coordinate | coordinate | time | time | systems | systems | satellite | satellite | geodetic | geodetic | orbital | orbital | motions | motions | pseudo ranges | pseudo ranges | carrier phases | carrier phases | stochastic | stochastic | mathematics | mathematics | models | models | data | data | analysis | analysis | estimation | estimation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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ESD.260J Logistics Systems (MIT) ESD.260J Logistics Systems (MIT)

Description

This course is a survey of analytic tools, approaches, and techniques which are useful in the design and operation of logistics systems and integrated supply chains. The material is taught from a managerial perspective, with an emphasis on where and how specific tools can be used to improve the overall performance and reduce the total cost of a supply chain. There is a strong emphasis on the development and use of fundamental models to illustrate the underlying concepts involved in both intra- and inter-company logistics operations. The following topics are covered: demand forecasting tools, inventory control algorithms, transportation operations and management, vehicle routing, scheduling, fleet dispatching algorithms and approaches, optimization of transportation carrier operations, supp This course is a survey of analytic tools, approaches, and techniques which are useful in the design and operation of logistics systems and integrated supply chains. The material is taught from a managerial perspective, with an emphasis on where and how specific tools can be used to improve the overall performance and reduce the total cost of a supply chain. There is a strong emphasis on the development and use of fundamental models to illustrate the underlying concepts involved in both intra- and inter-company logistics operations. The following topics are covered: demand forecasting tools, inventory control algorithms, transportation operations and management, vehicle routing, scheduling, fleet dispatching algorithms and approaches, optimization of transportation carrier operations, supp

Subjects

Logistics systems | Logistics systems | Supply chain management | Supply chain management | Demand planning | Demand planning | Procurement | Procurement | Inventory | Inventory | Transportation planning | Transportation planning | Reverse logistics | Reverse logistics | Flexible contracting | Flexible contracting | Postponement | Postponement | Portfolio management | Portfolio management | Dual sourcing | Dual sourcing | demand forecasting tools | demand forecasting tools | inventory control algorithms | inventory control algorithms | transportation operations | transportation operations | vehicle routing | vehicle routing | scheduling | scheduling | fleet dispatching algorithms | fleet dispatching algorithms | optimization | optimization | transportation carrier operations | transportation carrier operations | supply chain network design | supply chain network design | procurement | procurement | sourcing | sourcing | auctions | auctions | supply contracts | supply contracts | collaboration | collaboration | supply chain uncertainty | supply chain uncertainty | ESD.260 | ESD.260 | 1.260 | 1.260 | 15.770 | 15.770

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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2.57 Nano-to-Macro Transport Processes (MIT) 2.57 Nano-to-Macro Transport Processes (MIT)

Description

Includes audio/video content: AV lectures. Parallel treatments of photons, electrons, phonons, and molecules as energy carriers, aiming at fundamental understanding and descriptive tools for energy and heat transport processes from nanoscale continuously to macroscale. Topics include the energy levels, the statistical behavior and internal energy, energy transport in the forms of waves and particles, scattering and heat generation processes, Boltzmann equation and derivation of classical laws, deviation from classical laws at nanoscale and their appropriate descriptions, with applications in nano- and microtechnology. Includes audio/video content: AV lectures. Parallel treatments of photons, electrons, phonons, and molecules as energy carriers, aiming at fundamental understanding and descriptive tools for energy and heat transport processes from nanoscale continuously to macroscale. Topics include the energy levels, the statistical behavior and internal energy, energy transport in the forms of waves and particles, scattering and heat generation processes, Boltzmann equation and derivation of classical laws, deviation from classical laws at nanoscale and their appropriate descriptions, with applications in nano- and microtechnology.

Subjects

nanotechnology | nanotechnology | nanostructure | nanostructure | energy | energy | energy transport | energy transport | energy storage | energy storage | energy carriers | energy carriers | quantum mechanics | quantum mechanics | quantum physics | quantum physics | thermoelectrics | thermoelectrics | semiconductor physics | semiconductor physics | solar cells | solar cells | waves and particles | waves and particles

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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1.224J Carrier Systems (MIT) 1.224J Carrier Systems (MIT)

Description

Carrier systems involve the design, operation and management of transportation networks, assets, personnel, freight and passengers. In this course, we will present models and tools for analyzing, optimizing, planning, managing and controlling carrier systems. Carrier systems involve the design, operation and management of transportation networks, assets, personnel, freight and passengers. In this course, we will present models and tools for analyzing, optimizing, planning, managing and controlling carrier systems.

Subjects

carrier systems | carrier systems | design | design | operation | operation | management | management | personnel | personnel | freight and passengers | freight and passengers | models and tools for analyzing | models and tools for analyzing | optimization | optimization | planning | planning | managing and controlling | managing and controlling | transportation networks | transportation networks | assets | assets | freight | freight | passengers | passengers | models | models | tools | tools | analyzing | analyzing | optimizing | optimizing | managing | managing | controlling | controlling | linear programming | linear programming | software | software | integer programming | integer programming | direct transportation | direct transportation | procurement | procurement | transit vehicle scheduling | transit vehicle scheduling | transit crew scheduling | transit crew scheduling | airline routing | airline routing | real-time operations control | real-time operations control | freight transportation | freight transportation | analysis | analysis | plans | plans | control | control | designing | designing | 1.224 | 1.224 | ESD.204 | ESD.204

License

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6.012 Microelectronic Devices and Circuits (MIT) 6.012 Microelectronic Devices and Circuits (MIT)

Description

6.012 is the header course for the department's "Devices, Circuits and Systems" concentration. The topics covered include modeling of microelectronic devices, basic microelectronic circuit analysis and design, physical electronics of semiconductor junction and MOS devices, relation of electrical behavior to internal physical processes, development of circuit models, and understanding the uses and limitations of various models. The course uses incremental and large-signal techniques to analyze and design bipolar and field effect transistor circuits, with examples chosen from digital circuits, single-ended and differential linear amplifiers, and other integrated circuits. 6.012 is the header course for the department's "Devices, Circuits and Systems" concentration. The topics covered include modeling of microelectronic devices, basic microelectronic circuit analysis and design, physical electronics of semiconductor junction and MOS devices, relation of electrical behavior to internal physical processes, development of circuit models, and understanding the uses and limitations of various models. The course uses incremental and large-signal techniques to analyze and design bipolar and field effect transistor circuits, with examples chosen from digital circuits, single-ended and differential linear amplifiers, and other integrated circuits.

Subjects

semiconductor | semiconductor | integrated circuit | integrated circuit | p-n junction | p-n junction | mos | mos | mosfet | mosfet | digital logic | digital logic | nmos | nmos | cmos | cmos | bipolar junction transistor | bipolar junction transistor | single stage amplifier | single stage amplifier | frequency domain analysis | frequency domain analysis | common emitter | common emitter | multistage amplifier | multistage amplifier | intrinsic semiconductors | intrinsic semiconductors | electrons | electrons | holes | holes | carrier transport | carrier transport | 60mV rule | 60mV rule

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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6.012 Microelectronic Devices and Circuits (MIT) 6.012 Microelectronic Devices and Circuits (MIT)

Description

6.012 is the header course for the department's "Devices, Circuits and Systems" concentration. The topics covered include: modeling of microelectronic devices, basic microelectronic circuit analysis and design, physical electronics of semiconductor junction and metal-on-silicon (MOS) devices, relation of electrical behavior to internal physical processes, development of circuit models, and understanding the uses and limitations of various models. The course uses incremental and large-signal techniques to analyze and design bipolar and field effect transistor circuits, with examples chosen from digital circuits, single-ended and differential linear amplifiers, and other integrated circuits. 6.012 is the header course for the department's "Devices, Circuits and Systems" concentration. The topics covered include: modeling of microelectronic devices, basic microelectronic circuit analysis and design, physical electronics of semiconductor junction and metal-on-silicon (MOS) devices, relation of electrical behavior to internal physical processes, development of circuit models, and understanding the uses and limitations of various models. The course uses incremental and large-signal techniques to analyze and design bipolar and field effect transistor circuits, with examples chosen from digital circuits, single-ended and differential linear amplifiers, and other integrated circuits.

Subjects

semiconductor | semiconductor | integrated circuit | integrated circuit | p-n junction | p-n junction | mos | mos | mosfet | mosfet | digital logic | digital logic | nmos | nmos | cmos | cmos | bipolar junction transistor | bipolar junction transistor | single stage amplifier | single stage amplifier | frequency domain analysis | frequency domain analysis | common emitter | common emitter | multistage amplifier | multistage amplifier | intrinsic semiconductors | intrinsic semiconductors | electrons | electrons | holes | holes | carrier transport | carrier transport | 60mV rule | 60mV rule

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT) 7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT)

Description

The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an

Subjects

immune system | immune system | immunoengineering | immunoengineering | vaccines | vaccines | immunotherapies | immunotherapies | systems immunology | systems immunology | multivariate profiling | multivariate profiling | regulatory network analyses | regulatory network analyses | vaccine design | vaccine design | immunomodulation | immunomodulation | autoimmunity | autoimmunity | vaccine carriers | vaccine carriers | tolerogenic particle vaccines | tolerogenic particle vaccines | pathogen-mimicking | pathogen-mimicking | lipid nanoparticle vaccines | lipid nanoparticle vaccines

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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The 'Iron Ore' ready for launch

Description

Aerial view of the Southwick Yard of Austin & Pickersgill Ltd and the surrounding area, 8 July 1959 (TWAM ref. DT.TUR/2/22435B). The image shows the ore carrier ?Iron Ore? ready for launch. Tyne & Wear Archives is proud to present a selection of images from its Sunderland shipbuilding collections. The set has been produced to celebrate Sunderland History Fair on 7 June 2014. It's a reminder of the thousands of vessels launched on the River Wear and the many outstanding achievements of Sunderland?s shipyards and their workers. These photographs reflect Sunderland?s history of innovation in shipbuilding and marine engineering from the development of turret ships in the 1890s through to the design for SD14s in the 1960s. The Sunderland shipbuilding collections are full of fascinating stories. Some of these are represented in this set, such as the ?Rondefjell?, launched in two halves on the River Wear by John Crown & Sons Ltd and then joined together on the River Tyne. The set also shows the vital part that Sunderland?s shipbuilding industry played during the First World War. William Doxford & Sons Ltd built Royal Naval destroyers such as HMS Opal, which served in the Battle of Jutland, while other yards constructed cargo ships to help keep these shores supplied. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

sunderland | shipbuilding | austinpickersgillltd | shiplaunches | orecarrier | southwicksunderland | shipyard | riverwear | aerialphotograph | blackandwhitephotograph | sunderlandlaunches | aerial | northeastofengland | unitedkingdom | cityofsunderland | ironore | launch | southwickyard | surroundingarea | land | 8july1959 | shipbuildingheritage | maritimeheritage | industrialheritage | industry | abstract | archives | digitalimage | river | sunderlandhistoryfair | 7june2014 | vessel | marineengineering | production | soil | pile | bank | crane | structure | platform | buildings | shadow | daylight | rail | deck | cabin | carrier | cargo | transportation | fascinating | impressive | unusual | interesting | vegetation | water | road | signage | letter | row | housing | vehicle

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HMS Ark Royal - Final sea trials - 13th April 1985

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-8-51 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | seatrials

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HMS Ark Royal - 16th March 1985

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-54 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard | drydock | gravingdock | bow

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HMS Ark Royal - 27th April 1984

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-44 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard | skijump

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HMS Ark Royal - 30th January 1984

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-41 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | harbour | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard

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HMS Ark Royal - Launch - 20th JUNE 1981

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-31 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard | slipway | shiplaunching | launch

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HMS Ark Royal - 6th May 1981

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-18 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard | skijump | blackandwhite | striking | uknavalheritage | bosnianwar | iraqinvasion | volcaniceruption

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HMS Ark Royal - 10th March 1981

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-14 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard

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HMS Ark Royal - under construction - 13th March 1979

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-3 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard | keel

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HMS Ark Royal - 20th October 1980

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-10 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard

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HMS Ark Royal - 7th July 1980

Description

HMS Ark Royal was the former flagship of the Royal Navy. One of three Invincible class aircraft carriers she was affectionately known as The Mighty Ark. Her keel was laid by Swan Hunter at Wallsend on 7th December 1978 and she was launched on 20th June 1981 and completed in 1985. Major deployments included the Bosnian war (1993) and the invasion of Iraq (2003). More recently, she assisted in the repatriation of air travellers stranded by the 2010 volcanic eruption. Most photographs and images in this set are taken from the Swan Hunter Collection held by Tyne and Wear Archives Service. Ref: TWAS:ds-swh-4-ph-5-109-7 (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk. To purchase a hi-res copy please email archives@twmuseums.org.uk quoting the title and reference number.

Subjects

museum | twam | tyne | wear | archives | museums | ships | ship | builders | north | east | black | white | photos | royal | navy | swan | hunter | shipbuilding | hms | ark | wallsend | mighty | invincible | class | aircraft | carriers | flagship | warship | throughdeckcruiser | aircraftcarrier | navalaviation | royalnavy | rn | hmsarkroyalr07 | hmsarkroyal | r07 | arkroyal | invincibleclass | swanhunter | shipyard

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