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7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT) 7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT)

Description

Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a

Subjects

genome sequencing | genome sequencing | genome analysis | genome analysis | disease susceptibility | disease susceptibility | drug metabolism | drug metabolism | human ancestry | human ancestry | mitochondrial DNA | mitochondrial DNA | tyrosine kinase inhibitors | tyrosine kinase inhibitors | BCR-ABL gene fusion | BCR-ABL gene fusion | PCSK9 inhibitors | PCSK9 inhibitors | hypercholesterolemia | hypercholesterolemia | genetic testing | genetic testing | next generation sequencing | next generation sequencing | Single-nucleotide polymorphisms (SNPs) | Single-nucleotide polymorphisms (SNPs) | copy number variations (CNVs) | copy number variations (CNVs) | genome-wide association studies (GWAS) | genome-wide association studies (GWAS) | Chronic myelogenous leukemia (CML) | Chronic myelogenous leukemia (CML) | mosaics | mosaics | chimeras | chimeras | bioinformatics | bioinformatics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Notre Dame de Paris. Tower

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01424 Title: Notre Dame de Paris. Tower Architect: Eugene-Emanuel Viollet-le-Duc (French, 1814-1879) Sculpture Date: 1845-1868 Photograph date: ca. 1865-ca. 1886 Location: Europe: France; Paris Materials: albumen print Image: 11.0236 x 14.8819 in.; 28 x 37.8 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tmx There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | notredamecathedralparisfrance | cathedrals | religiousbuildings | grotesques | chimeras | imaginarymythologicalcreatures | balconies | wroughtiron | rooftops | culidentifier:value=155309001424 | culidentifier:lunafield=accessionnumber

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Notre Dame de Paris. Tower with Chimeras

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01426 Title: Notre Dame de Paris. Tower with Chimeras Architect: Eugene-Emanuel Viollet-le-Duc (French, 1814-1879) Sculpture Date: 1845-1868 Photograph date: ca. 1865-ca. 1886 Location: Europe: France; Paris Materials: albumen print Image: 10.7087 x 14.7244 in.; 27.2 x 37.4 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tn0 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | notredamecathedralparisfrance | cathedrals | religiousbuildings | towers | balconies | quatrefoils | chimeras | grotesques | pelicans | birds | animals | imaginarymythologicalcreatures | plantderivedmotifs | rooftops | culidentifier:value=155309001426 | culidentifier:lunafield=accessionnumber

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Amiens Cathedral Gargoyles

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01427 Title: Amiens Cathedral Gargoyles Photograph date: ca. 1865-ca. 1886 Location: Europe: France; Paris Materials: albumen print Image: 10.748 x 13.8583 in.; 27.3 x 35.2 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tn1 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | amienscathedralamiensfrance | cathedrals | religiousbuildings | towers | balconies | gargoyles | chimeras | grotesques | imaginarymythologicalcreatures | dogs | animals | sculpture | harps | musicalinstruments | kingspeople | crowns | culidentifier:value=155309001427 | culidentifier:lunafield=accessionnumber

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Notre Dame de Paris. View from Tower with Chimeras and Gargoyles

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01425 Title: Notre Dame de Paris. View from Tower with Chimeras and Gargoyles Architect: Eugene-Emanuel Viollet-le-Duc (French, 1814-1879) Sculpture Date: 1845-1868 Photograph date: ca. 1865-ca. 1886 Location: Europe: France; Paris Materials: albumen print Image: 10.4331 x 14.8425 in.; 26.5 x 37.7 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tmz There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | notredamecathedralparisfrance | cathedrals | religiousbuildings | rooftops | angels | wings | trumpets | musicalinstruments | music | gargoyles | grotesques | chimeras | imaginarymythologicalcreatures | animals | elephants | pelicans | birds | sculpture | spires | crockets | culidentifier:value=155309001425 | culidentifier:lunafield=accessionnumber

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Two Grotesques

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01577 Title: Two Grotesques Photograph date: ca. 1865-ca. 1895 Location: Europe: France Materials: albumen print Image: 7.6378 x 10.75 in.; 19.4 x 27.305 cm Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tsm There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | grotesques | sculpture | imaginarymythologicalcreatures | bats | animals | chimeras | helmets | wings | birds | architecture | culidentifier:value=155309001577 | culidentifier:lunafield=accessionnumber

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Paris. Notre Dame Cathedral Tower. Chimeras and Man

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00628 Title: Paris. Notre Dame Cathedral Tower. Chimeras and Man Sculpture Date: 1845-1868 Photograph date: ca. 1865-ca. 1886 Location: Europe: France; Paris Materials: albumen print Image: 10.8268 x 14.8031 in.; 27.5 x 37.6 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sr1 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | cathedrals | religiousbuildings | notredamecathedralparisfrance | grotesques | towers | imaginarymythologicalcreatures | eagles | birds | animals | balconies | chimeras | culidentifier:value=155309000628 | culidentifier:lunafield=accessionnumber | gargouilles

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7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT)

Description

Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a

Subjects

genome sequencing | genome analysis | disease susceptibility | drug metabolism | human ancestry | mitochondrial DNA | tyrosine kinase inhibitors | BCR-ABL gene fusion | PCSK9 inhibitors | hypercholesterolemia | genetic testing | next generation sequencing | Single-nucleotide polymorphisms (SNPs) | copy number variations (CNVs) | genome-wide association studies (GWAS) | Chronic myelogenous leukemia (CML) | mosaics | chimeras | bioinformatics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allcourses.xml

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