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7.03 Genetics (MIT) 7.03 Genetics (MIT)

Description

The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease. The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subjects

Population genetics | Population genetics | selection | selection | mutation | mutation | recombination | recombination | genomes | genomes | chromosomes | chromosomes | genes | genes

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.60 Cell Biology: Structure and Functions of the Nucleus (MIT) 7.60 Cell Biology: Structure and Functions of the Nucleus (MIT)

Description

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression. The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Subjects

cell biology | cell biology | nucleus | nucleus | biology | biology | nuclear cell biology | nuclear cell biology | DNA replication | DNA replication | DNA repair | DNA repair | DNA | DNA | genome | genome | cell cycle control | cell cycle control | transcriptional regulation | transcriptional regulation | gene expression | gene expression | chromatin | chromatin | chromosomes | chromosomes | replication | replication | transcription | transcription | RNA | RNA | RNA interference | RNA interference | mRNA | mRNA | microRNA | microRNA | RNAi | RNAi

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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HST.161 Molecular Biology and Genetics in Modern Medicine (MIT) HST.161 Molecular Biology and Genetics in Modern Medicine (MIT)

Description

This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics. This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics.

Subjects

Genetics | Genetics | genes | genes | genetic disorders | genetic disorders | inborn error | inborn error | muscular dystrophy | muscular dystrophy | PKU | PKU | phenylketoneuria | phenylketoneuria | cancer | cancer | tumors | tumors | gene therapy | gene therapy | disease | disease | birth defects | birth defects | chromosomes | chromosomes | leukemia | leukemia | RNAi | RNAi | hemophilia | hemophilia | thalassemia | thalassemia | deafness | deafness | mutations | mutations | hypertrophic cardiomyopathy | hypertrophic cardiomyopathy | epigenetics | epigenetics | rett syndrome | rett syndrome | prenatal diagnosis | prenatal diagnosis | LOD scores | LOD scores | gene linkage | gene linkage | mitochondrial disorders | mitochondrial disorders | degenerative disorders | degenerative disorders | complex traits | complex traits | Mendelian inheritance | Mendelian inheritance

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Human Chromosomes

Description

An interactive e-learning resource to explore Human Chromosomes and the consequences of changes in chromosome number to health and development.

Subjects

chromosomes | health | development | genetics | human chromosomes | coventry university | cele | dentistry | A000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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What is the genome made of? What is the genome made of?

Description

Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated; and it carries a store of vital information that is used in the cell to produce proteins. The first two properties of DNA are analysed in this free course, What is the genome made of? First published on Thu, 24 Mar 2016 as What is the genome made of?. To find out more visit The Open University's O Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated; and it carries a store of vital information that is used in the cell to produce proteins. The first two properties of DNA are analysed in this free course, What is the genome made of? First published on Thu, 24 Mar 2016 as What is the genome made of?. To find out more visit The Open University's O

Subjects

Biology | Biology | reactor | reactor | genetics | genetics | chromosomes | chromosomes | 60 Second Adventures In Astronomy | 60 Second Adventures In Astronomy | Southbank Centre | Southbank Centre | SK195_2 | SK195_2

License

Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence Licensed under a Creative Commons Attribution - NonCommercial-ShareAlike 2.0 Licence - see http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ - Original copyright The Open University

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Inheritance of characters Inheritance of characters

Description

Genes are units of inheritance that contribute to a person's behaviour and health. In this free course, Inheritance of characters, you will learn what genes, DNA and chromosomes are and how they combine to make the human genome. You will also learn how the principles of inheritance work, the effect that our genetic make-up has on health, and how genetic material is passed on from generation to generation. First published on Thu, 24 Mar 2016 as Inheritance of characters. To find out more visit The Open University's Openlearn website. Creative-Commons 2016 Genes are units of inheritance that contribute to a person's behaviour and health. In this free course, Inheritance of characters, you will learn what genes, DNA and chromosomes are and how they combine to make the human genome. You will also learn how the principles of inheritance work, the effect that our genetic make-up has on health, and how genetic material is passed on from generation to generation. First published on Thu, 24 Mar 2016 as Inheritance of characters. To find out more visit The Open University's Openlearn website. Creative-Commons 2016 First published on Thu, 24 Mar 2016 as Inheritance of characters. To find out more visit The Open University's Openlearn website. Creative-Commons 2016 First published on Thu, 24 Mar 2016 as Inheritance of characters. To find out more visit The Open University's Openlearn website. Creative-Commons 2016

Subjects

Biology | Biology | inheritance | inheritance | genetics | genetics | information | information | chromosomes | chromosomes | mitosis | mitosis | SK195_1 | SK195_1

License

Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence Licensed under a Creative Commons Attribution - NonCommercial-ShareAlike 2.0 Licence - see http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ - Original copyright The Open University

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Early development Early development

Description

This free course, Early development, looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy. First published on Thu, 24 Mar 2016 as Early development. To fi This free course, Early development, looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy. First published on Thu, 24 Mar 2016 as Early development. To fi First published on Thu, 24 Mar 2016 as Early development. To find out more visit The Open University's Openlearn website. Creative-Commons 2016 First published on Thu, 24 Mar 2016 as Early development. To find out more visit The Open University's Openlearn website. Creative-Commons 2016

Subjects

Biology | Biology | family | family | contraception | contraception | pregnancies | pregnancies | child development | child development | conception | conception | reproduction | reproduction | poison | poison | Paul Gilroy | Paul Gilroy | news cloud | news cloud | chromosomes | chromosomes | The Sound and the Fury | The Sound and the Fury | hormones | hormones | embryo | embryo | Living with poverty | Living with poverty | development | development | Pussy Riot | Pussy Riot | SK220_1 | SK220_1

License

Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence Licensed under a Creative Commons Attribution - NonCommercial-ShareAlike 2.0 Licence - see http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ - Original copyright The Open University

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Meiosis and mitosis

Description

This Unit looks at how units if inheritance are transmitted from one generation to the next. First you will look at what happens to the chromosones of animals and plants during the process of sexual reproduciton. Then you will examine how genes are transmitted in particular patterns from generation to generation. These two approaches combine to illustrate how the patterns of inheritance can be explained by the behaviour of chromosomes during sexual reproduction.

Subjects

science and nature | chromosomes | gene | genotype | inheritance | karyotype | meiosis | mitosis | phenotype | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Nucleic acids and chromatin

Description

This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell, their interactions with each other and the use of ribozymes, aptamers, antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell, the interactions between the DNA double helix and the nucleosome and it helps you understand the various chromatin states within the interphase nucleus.

Subjects

science and nature | chromatin | chromosomes | dna | double-helix | electrophoresis | histones | hybridization | mutation | nucleoprotein | nucleosomes | rna | topoisomerase | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Inheritance of characters

Description

Genes are units of inheritance that contribute to a person’s behaviour and health. In this unit you will learn what genes, DNA and chromosomes are and how they combine to make the human genome. You will also learn how the principles of inheritance work, the effect that our genetic make-up has on health, and how genetic material is passed on from generation to generation.

Subjects

science and nature | chromosomes | dna | fertilization | genes | genetics | information | inheritance | meiosis | mitosis | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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What is the genome made of?

Description

Genomes are composed of DNA, and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable, breathtakingly simple in its structure yet capable of directing all the living processes in a cell, the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated, or replicated; and it carries a store of vital information that is used in the cell to produce proteins. The first two properties of DNA are analysed in this unit.

Subjects

science and nature | chromosomes | dna | dna_replication | dna_sequence | double-helix | genes | genetics | genome | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Early development

Description

This unit looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy.

Subjects

science and nature | abortion | birth_rate | child_development | chromosomes | conception | contraception | development | embryo | family | fertilization | gametes | hormones | infertility | lifecycle | meiosis | ovulation | pregnancy | reproduction | sex_selection | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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DNA Genes and Chromosomes

Description

Please visit the Virtual Genetics Education Centre in GENIE for more first-class OERs.

Subjects

dna genes and chromosomes dna genetics genes dna replication sequecing chromosome | Subjects allied to medicine | B000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Down's syndrome

Description

This topic describes the main features of Down's syndrome and is accompanied by photographs highlighting dysmorphic features. Graphical and tabular information illustrate the intellectual capacity, life expectancy, functional ability and social independence, and medical checks of those with Down's syndrome.

Subjects

chromosome 21 | trisomy 21 | 47 chromosomes | extra genetic material | slant eyes | large tongue | ukoer | ooer | medev | Medicine and Dentistry | Biological Sciences | Subjects allied to Medicine | SAFETY | Learning | Teaching | Institutions | Students | UK EL07 = SCQF 7 | Higher Certificate | NICAT 4 | CQFW 4 | NVQ 4 | Advanced Higher | SVQ 4 | HN Certificate | dentistry | A000

License

Attribution-Share Alike 2.0 UK: England & Wales Attribution-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-sa/2.0/uk/ http://creativecommons.org/licenses/by-sa/2.0/uk/

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Molecular Biology

Description

After a historical introduction to molecular biology, this course describes the basic types of DNA and RNA structure and the molecular interactions that shape them. It describes how DNA is packaged within the cellular nucleus as chromosomes. It also describes the core processes of molecular biology: replication of DNA, transcription of DNA into messenger RNA, and translation of messenger RNA into a protein. These are followed by modifications of these basic processes: regulation of gene expression, DNA mutation and repair, and DNA recombination and transposition. This free course may be completed online at any time. See course site for detailed overview and learning outcomes. (Biology 311)

Subjects

biology | molecules | molecular biology | dna | genes | genetics | rna | chromosomes | replication | transcription | synthesis | code | regulation | expression | mutation | Biological sciences | C000

License

Attribution 2.0 UK: England & Wales Attribution 2.0 UK: England & Wales http://creativecommons.org/licenses/by/2.0/uk/ http://creativecommons.org/licenses/by/2.0/uk/

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Biochemistry

Description

Biochemistry is the study of the chemical processes and compounds, such as cellular makeup, that bring about life in organisms. This course will look at how these formed biomolecules interact and produce many of life’s necessary processes. Also it will look at the most commonly used techniques in biochemistry research. This free course may be completed online at any time. See course site for detailed overview and learning outcomes. (Biology 401; See also: Chemistry 109)

Subjects

biology | chemistry | biochemistry | amino acids | proteins | enzymes | carbohydrates | nucleic acids | lipids | metabolism | genes | chromosomes | Biological sciences | C000

License

Attribution 2.0 UK: England & Wales Attribution 2.0 UK: England & Wales http://creativecommons.org/licenses/by/2.0/uk/ http://creativecommons.org/licenses/by/2.0/uk/

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Meiosis and mitosis

Description

This free course looks at how units of inheritance are transmitted from one generation to the next. First you will look at what happens to the chromosomes of animals and plants during the process of sexual reproduction. Then you will examine how genes are transmitted in particular patterns from generation to generation. These two approaches combine to illustrate how the patterns of inheritance can be explained by the behaviour of chromosomes during sexual reproduction.

Subjects

Biology | mitosis | inheritance | chromosomes

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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What is the genome made of?

Description

Genomes are composed of DNA and a knowledge of the structure of DNA is essential to understand how it can function as hereditary material. DNA is remarkable breathtakingly simple in its structure yet capable of directing all the living processes in a cell the production of new cells and the development of a fertilized egg to an individual adult. DNA has three key properties: it is relatively stable; its structure suggests an obvious way in which the molecule can be duplicated or replicated; and it carries a store of vital information that is used in the cell to produce proteins. The first two properties of DNA are analysed in this free course

Subjects

Biology | reactor | genetics | chromosomes | 60 Second Adventures In Astronomy | Southbank Centre | SK195_2

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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Inheritance of characters

Description

Genes are units of inheritance that contribute to a person's behaviour and health. In this free course you will learn what genes DNA and chromosomes are and how they combine to make the human genome. You will also learn how the principles of inheritance work the effect that our genetic make-up has on health

Subjects

Biology | inheritance | genetics | information | chromosomes | mitosis | SK195_1

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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Early development

Description

This free course looks at the human being in the context of an individual life cycle examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception and about contraception to the present day we look at the cells involved in the conception and development of a new individual. Gamete production (that is production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and when things go wrong infertility is explained. We then discuss the early development of a new individual

Subjects

Biology | family | contraception | pregnancies | child development | conception | reproduction | poison | Paul Gilroy | news cloud | chromosomes | The Sound and the Fury | hormones | embryo | Living with poverty | development | Pussy Riot | SK220_1

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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Nucleic acids and chromatin

Description

This unit helps you understand the properties of nucleotides and how they contribute to secondary and tertiary structures of nucleic acids at the molecular level. You will learn about the different composition and roles of nucleic acids in the cell their interactions with each other and the use of ribozymes aptamers antisense and hybridization as tools in molecular research. The unit covers the function of DNA packaging within the cell the interactions between the DNA double helix and the nucleosome and it helps you understand the various chromatin states within the interphase nucleus.

Subjects

Biology | chromosomes | referencing | French courses | French culture | Language | Ouverture | beginners | S377_1

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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7.03 Genetics (MIT)

Description

The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subjects

Population genetics | selection | mutation | recombination | genomes | chromosomes | genes

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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7.60 Cell Biology: Structure and Functions of the Nucleus (MIT)

Description

The goal of this course is to teach both the fundamentals of nuclear cell biology as well as the methodological and experimental approaches upon which they are based. Lectures and class discussions will cover the background and fundamental findings in a particular area of nuclear cell biology. The assigned readings will provide concrete examples of the experimental approaches and logic used to establish these findings. Some examples of topics include genome and systems biology, transcription, and gene expression.

Subjects

cell biology | nucleus | biology | nuclear cell biology | DNA replication | DNA repair | DNA | genome | cell cycle control | transcriptional regulation | gene expression | chromatin | chromosomes | replication | transcription | RNA | RNA interference | mRNA | microRNA | RNAi

License

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HST.161 Molecular Biology and Genetics in Modern Medicine (MIT)

Description

This course provides a foundation for understanding the relationship between molecular biology, developmental biology, genetics, genomics, bioinformatics, and medicine. It develops explicit connections between basic research, medical understanding, and the perspective of patients. Principles of human genetics are reviewed. We translate clinical understanding into analysis at the level of the gene, chromosome and molecule; we cover the concepts and techniques of molecular biology and genomics, and the strategies and methods of genetic analysis, including an introduction to bioinformatics. Material in the course extends beyond basic principles to current research activity in human genetics.

Subjects

Genetics | genes | genetic disorders | inborn error | muscular dystrophy | PKU | phenylketoneuria | cancer | tumors | gene therapy | disease | birth defects | chromosomes | leukemia | RNAi | hemophilia | thalassemia | deafness | mutations | hypertrophic cardiomyopathy | epigenetics | rett syndrome | prenatal diagnosis | LOD scores | gene linkage | mitochondrial disorders | degenerative disorders | complex traits | Mendelian inheritance

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Meiosis and mitosis

Description

This free course

Subjects

Biology | mitosis | inheritance | chromosomes

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

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