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1

sdasm image

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douglasad5q | douglasea1f | buno133770 | 133770 | ea1f | vaw113 | skyraider | aviation | aircraft | airplane | militaryaviation | navalaviation | electroniccountermeasures | ecm | electronicwarfare | ew | douglasaircraftcompany | douglasaircraft | douglas | dac | douglasadskyraider | douglasad | douglasskyraider | adskyraider | douglasa1skyraider | douglasa1 | a1skyraider | a1 | douglasad5skyraider | douglasad5 | ad5skyraider | ad5 | douglasad5wskyraider | douglasad5w | ad5wskyraider | ad5w | douglasea1eskyraider | douglasea1e | ea1eskyraider | ea1e | wrightaeronautical | wright | wrightr3350 | r3350 | wrightr335026 | r335026 | wrightr335026wa | r335026wa | unitedstatesnavy | usnavy | usn

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sdasm image

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buno132521 | 132521 | unitedstatesnavy | usnavy | usn | aviation | aircraft | airplane | militaryaviation | navalaviation | douglasaircraftcompany | douglasaircraft | douglas | dac | douglasadskyraider | douglasad | douglasskyraider | adskyraider | douglasa1skyraider | douglasa1 | a1skyraider | a1 | douglasad5skyraider | douglasad5 | ad5skyraider | ad5 | douglasad5nskyraider | douglasad5n | ad5nskyraider | ad5n | douglasa1gskyraider | douglasa1g | a1gskyraider | a1g | wrightaeronautical | wright | wrightr3350 | r3350 | wrightr335026 | r335026 | wrightr335026wa | r335026wa

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Bolduc_30.tif Theodore Bolduc Collection Image

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Subjects

unitedstatesnavy | usnavy | usn | militaryaviation | aviation | aircraft | airplane | navalaviation | divebomber | douglasaircraftcompany | dac | douglasaircraft | douglas | douglassbddauntless | douglasdauntless | douglassbd | sbddauntless | sbd | douglassbd5dauntless | douglassbd5 | sbd5dauntless | sbd5 | wrightr1820 | wrightcyclone | r1820 | wrightcycloner1820 | r182060

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Ford 5-AT-C cn 73 NC413H United AL Ford 5-AT-C cn 73 NC413H United AL

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Subjects

ford | ford | airplane | airplane | aircraft | aircraft | aviation | aviation | united | united | aeroplane | aeroplane | passengers | passengers | airlines | airlines | ual | ual | airliner | airliner | stout | stout | airliners | airliners | unitedairlines | unitedairlines | prattwhitney | prattwhitney | fordtrimotor | fordtrimotor | trimotor | trimotor | tingoose | tingoose | prattwhitneywasp | prattwhitneywasp | anaam | anaam | stoutmetalairplanecompany | stoutmetalairplanecompany | wrightaeronautical | wrightaeronautical | ford5atc | ford5atc | waspradial | waspradial | ford5atctrimotor | ford5atctrimotor | nc413h | nc413h | cn5at73 | cn5at73 | 5at73 | 5at73 | xhtaq | xhtaq | lgtaq | lgtaq | lgaad | lgaad

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Dunne, Biplane Dunne, Biplane

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Subjects

uk | uk | england | england | woman | woman | man | man | paris | paris | kent | kent | wings | wings | unitedkingdom | unitedkingdom | philosophy | philosophy | aeroplane | aeroplane | getty | getty | d8 | d8 | riverthames | riverthames | d3 | d3 | graces | graces | d5 | d5 | biplane | biplane | d1 | d1 | eastchurch | eastchurch | notail | notail | d4 | d4 | thechannel | thechannel | gutenberg | gutenberg | churchroad | churchroad | flyingmachine | flyingmachine | thomasmayne | thomasmayne | serialism | serialism | lanternslides | lanternslides | nationallibraryofireland | nationallibraryofireland | dryflyfishing | dryflyfishing | july1910 | july1910 | swaleborough | swaleborough | locationidentified | locationidentified | johnwilliamdunne | johnwilliamdunne | flightmagazine | flightmagazine | dateestablished | dateestablished | thewarintheair | thewarintheair | standfordhill | standfordhill | arcopublishing | arcopublishing | thomasholmesmason | thomasholmesmason | thomashmasonsonslimited | thomashmasonsonslimited | dunnebiplanesstickandstring | dunnebiplanesstickandstring | lieutenantdunne | lieutenantdunne | darlingdownsgazette | darlingdownsgazette | mrhgwells | mrhgwells | april9th1910 | april9th1910 | no5ateastchurch | no5ateastchurch | jane’salltheworld’saircraft1913 | jane’salltheworld’saircraft1913 | fredtjane | fredtjane | villacoublayairfield | villacoublayairfield | earlymilitaryaircraft | earlymilitaryaircraft | taillesssweptwingdesigns | taillesssweptwingdesigns | certifiedinherentlystableaircraft | certifiedinherentlystableaircraft | flyingwingdesign | flyingwingdesign | lateralstability | lateralstability

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7.341 DNA Damage Checkpoints: The Emergency Brake on the Road to Cancer (MIT) 7.341 DNA Damage Checkpoints: The Emergency Brake on the Road to Cancer (MIT)

Description

The DNA contained in human cells is under constant attack by both exogenous and endogenous agents that can damage one of its three billion base pairs. To cope with this permanent exposure to DNA-damaging agents, such as the sun's radiation or by-products of our normal metabolism, powerful DNA damage checkpoints have evolved that allow organisms to survive this constant assault on their genomes. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understanding of checkpoints that act as powerful emergency brakes to prevent cancer. We will consider basic principles of cell proliferation and molecular details of the DNA damage response. We will discuss the methods and model organisms typically used in this field as well as how an The DNA contained in human cells is under constant attack by both exogenous and endogenous agents that can damage one of its three billion base pairs. To cope with this permanent exposure to DNA-damaging agents, such as the sun's radiation or by-products of our normal metabolism, powerful DNA damage checkpoints have evolved that allow organisms to survive this constant assault on their genomes. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understanding of checkpoints that act as powerful emergency brakes to prevent cancer. We will consider basic principles of cell proliferation and molecular details of the DNA damage response. We will discuss the methods and model organisms typically used in this field as well as how an

Subjects

DNA | DNA | damage checkpoints | damage checkpoints | cancer | cancer | cells | cells | human cells | human cells | exogenous | exogenous | endogenous | endogenous | checkpoints | checkpoints | gene | gene | signaling | signaling | cancer biology | cancer biology | cancer prevention | cancer prevention | primary sources | primary sources | discussion | discussion | DNA damage | DNA damage | molecular | molecular | enzyme | enzyme | cell cycle | cell cycle | extracellular cues | extracellular cues | growth factors | growth factors | Cdk regulation | Cdk regulation | cyclin-dependent kinase | cyclin-dependent kinase | p53 | p53 | tumor suppressor | tumor suppressor | apoptosis | apoptosis | MDC1 | MDC1 | H2AX | H2AX | Rad50 | Rad50 | Fluorescence activated cell sorter | Fluorescence activated cell sorter | Chk1 | Chk1 | mutant | mutant

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Augusta Caroline Dillon seated in Clonbrock garden Augusta Caroline Dillon seated in Clonbrock garden

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ireland | ireland | estate | estate | cologne | cologne | greatwar | greatwar | templebar | templebar | 1920 | 1920 | limburg | limburg | connaught | connaught | 1837 | 1837 | obe | obe | countygalway | countygalway | meetinghousesquare | meetinghousesquare | shrubberies | shrubberies | birrcastle | birrcastle | nationalphotographicarchive | nationalphotographicarchive | nationallibraryofireland | nationallibraryofireland | ladyrosse | ladyrosse | dillonfamily | dillonfamily | connaughtrangers | connaughtrangers | ahascragh | ahascragh | eastgalway | eastgalway | clonbrockhouse | clonbrockhouse | roseshaw | roseshaw | clonbrockestate | clonbrockestate | augustacarolinedillon | augustacarolinedillon | baronessclonbrock | baronessclonbrock | theformalgarden | theformalgarden | redillon | redillon | theclonbrockphotographiccollection | theclonbrockphotographiccollection | augustacarolinecrofton | augustacarolinecrofton | 16thoctober1839 | 16thoctober1839 | died5thseptember1928 | died5thseptember1928 | clonbrocks | clonbrocks | theladiesofthelens | theladiesofthelens | greatexhibitioninlondonof1851 | greatexhibitioninlondonof1851 | ladyaugustacrofton’s | ladyaugustacrofton’s | rteshadows | rteshadows | ladyaugustacrofton | ladyaugustacrofton | michaelo’connell | michaelo’connell | withherwetplateprocesscamera | withherwetplateprocesscamera | dillonfamilyofclonbrock | dillonfamilyofclonbrock | orderofthebritishempirehonourslist | orderofthebritishempirehonourslist | baronessclonbock | baronessclonbock | irishwomen’sassociation | irishwomen’sassociation | irishpows | irishpows | bmaguire | bmaguire | 3000photographsfor£25in1976 | 3000photographsfor£25in1976 | countessofrossenéemaryfield | countessofrossenéemaryfield | britishamateurastronomer | britishamateurastronomer | pioneeringphotographer | pioneeringphotographer | waxedpapernegatives | waxedpapernegatives | terancedooley | terancedooley | 100ishyearsago | 100ishyearsago

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7.341 The DNA Damage Response as a Target for Anti-Cancer Therapy (MIT) 7.341 The DNA Damage Response as a Target for Anti-Cancer Therapy (MIT)

Description

Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subjects

DNA | DNA | damage checkpoints | damage checkpoints | cancer | cancer | cells | cells | human cells | human cells | exogenous | exogenous | endogenous | endogenous | checkpoints | checkpoints | gene | gene | signaling | signaling | cancer biology | cancer biology | cancer prevention | cancer prevention | primary sources | primary sources | discussion | discussion | DNA damage | DNA damage | molecular | molecular | enzyme | enzyme | cell cycle | cell cycle | extracellular cues | extracellular cues | growth factors | growth factors | Cdk regulation | Cdk regulation | cyclin-dependent kinase | cyclin-dependent kinase | p53 | p53 | tumor suppressor | tumor suppressor | apoptosis | apoptosis | MDC1 | MDC1 | H2AX | H2AX | Rad50 | Rad50 | Fluorescence activated cell sorter | Fluorescence activated cell sorter | Chk1 | Chk1 | mutant | mutant

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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AL-61B Album Image _00100

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Subjects

aviation | airplanes | albatros | dva | d539017 | leisureworldaerosapceclub

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7.341 DNA Damage Checkpoints: The Emergency Brake on the Road to Cancer (MIT)

Description

The DNA contained in human cells is under constant attack by both exogenous and endogenous agents that can damage one of its three billion base pairs. To cope with this permanent exposure to DNA-damaging agents, such as the sun's radiation or by-products of our normal metabolism, powerful DNA damage checkpoints have evolved that allow organisms to survive this constant assault on their genomes. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understanding of checkpoints that act as powerful emergency brakes to prevent cancer. We will consider basic principles of cell proliferation and molecular details of the DNA damage response. We will discuss the methods and model organisms typically used in this field as well as how an

Subjects

DNA | damage checkpoints | cancer | cells | human cells | exogenous | endogenous | checkpoints | gene | signaling | cancer biology | cancer prevention | primary sources | discussion | DNA damage | molecular | enzyme | cell cycle | extracellular cues | growth factors | Cdk regulation | cyclin-dependent kinase | p53 | tumor suppressor | apoptosis | MDC1 | H2AX | Rad50 | Fluorescence activated cell sorter | Chk1 | mutant

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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New York City. Plan for Entrance to Central Park

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01556 Title: New York City. Plan for Entrance to Central Park Designer: Richard Morris Hunt (American, 1827-1895) Design date: ca. 1863 Photograph date: ca. 1865-ca. 1885 Location: North and Central America: United States; New York, New York Materials: albumen print Image: 18.1102 x 20.2756 in.; 46 x 51.5 cm Style: Beaux-Arts Provenance: Transfer from the College of Architecture, Art and Planning Persistent URI: hdl.handle.net/1813.001/5ts7 There are no known U.S. copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | centralparkmanhattannewyork | architecturaldrawings | topographicalviews | urbanparks | columns | plazas | squaresopenspaces | hotelspublicaccommodations | churches | religiousbuildings | churchtowers | statues | fountains | centralpark | 59thand5th | fifthavenue | newyorkcity | manhattan | nyc | city | urbanplanning | planning | 59thstreet | newyork | culidentifier:value=155309001556 | culidentifier:lunafield=accessionnumber

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Mr Pettett in a class at the Royal Hospital School

Description

Reproduction ID: H1340 Maker: Unknown Date: circa 1850

Subjects

nationalmaritimemuseum | school | class | classroom | boys | children | uniforms | greenwich | royalhospitalschool | cl0412 | cl0412s1 | cl0412d5

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Royal Naval College floodlit for the coronation

Description

Reproduction ID: H1515 Maker: Unknown Date: May 1937

Subjects

nationalmaritimemuseum | greenwich | night | columns | cl0412 | cl0412s1 | cl0412d5

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The cutwater of the 'Parma', 1932–33

Description

Reproduction ID: N61381 Maker: Alan Villiers Date: 1932-33 Villiers collection www.nmm.ac.uk/visit/exhibitions/past/villiers-display/

Subjects

nationalmaritimemuseum | sea | ship | cl0412 | cl0412s1 | cl0412d5

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The mizzen of the 'Grace Harwar'; view aft from the main crosstrees, 1929

Description

Reproduction ID: N61253 Maker: Alan Villiers Date: 1929 Villiers collection www.nmm.ac.uk/visit/exhibitions/past/villiers-display/

Subjects

nationalmaritimemuseum | ship | sea | cl0412 | cl0412s1 | cl0412d5

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The watch going aloft on the 'Parma'

Description

Reproduction ID: N61533 Maker: Alan Villiers Date: 1932-33 Villiers collection www.nmm.ac.uk/visit/exhibitions/past/villiers-display/ If you would like to find out how you can use images from the National Maritime Museum, please visit our Collections pages.

Subjects

nationalmaritimemuseum | ship | sails | cl0412 | cl0412s1 | cl0412d5

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Furling sail on the main yard of the 'Parma'

Description

Reproduction ID: N61048 Maker: Alan Villiers Date: 1932-33 Villiers collection www.nmm.ac.uk/visit/exhibitions/past/villiers-display/ If you would like to find out how you can use images from the National Maritime Museum, please visit our Collections pages.

Subjects

nationalmaritimemuseum | ship | sea | sails | cl0412 | clews | allclewedup | cl0412s1 | cl0412d5

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Apprentice Elisabeth Jacobsen and Ruby De Cloux, daughter of the 'Parma’s' captain, Reuben De Cloux, on the poop

Description

Reproduction ID: N61739 Maker: Alan Villiers Date: 1933 Villiers collection www.nmm.ac.uk/visit/exhibitions/past/villiers-display/ If you would like to find out how you can use images from the National Maritime Museum, please visit our Collections pages.

Subjects

nationalmaritimemuseum | ship | cl0412 | cl0412s1 | cl0412d5

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The folks that live on the hill - in Renny, Co. Cork

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Subjects

robertfrench | williamlawrence | lawrencecollection | lawrencephotographicstudio | thelawrencephotographcollection | glassnegative | nationallibraryofireland | house | hill | cliff | trees | river | renny | cocork | countycork | blackwater | riverblackwater | riverawbeg | demolished | poulmaddy | kilcummer | fermoy | record50000

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7.341 The DNA Damage Response as a Target for Anti-Cancer Therapy (MIT)

Description

Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand of cell cycle regulation and DNA damage checkpoints that act as powerful emergency brakes to prevent cancer. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subjects

DNA | damage checkpoints | cancer | cells | human cells | exogenous | endogenous | checkpoints | gene | signaling | cancer biology | cancer prevention | primary sources | discussion | DNA damage | molecular | enzyme | cell cycle | extracellular cues | growth factors | Cdk regulation | cyclin-dependent kinase | p53 | tumor suppressor | apoptosis | MDC1 | H2AX | Rad50 | Fluorescence activated cell sorter | Chk1 | mutant

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Stan Abele Collection Image

Description

Subjects

airplane | aircraft | aviation | dac | douglas | usn | sbd | navalaviation | divebomber | ussbunkerhill | douglassbddauntless | wrightcyclone | r1820 | sbd5 | douglasaircraft | sbddauntless | douglassbd | douglasaircraftcompany | douglasdauntless | wrightcycloner1820 | wrightr1820 | stanabele | bombing303vb303

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