Searching for embryo : 31 results found | RSS Feed for this search

1

7.344 The Fountain of Life: From Dolly to Customized Embryonic Stem Cells (MIT) 7.344 The Fountain of Life: From Dolly to Customized Embryonic Stem Cells (MIT)

Description

During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which hav During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which hav

Subjects

embryonic stem cells | embryonic stem cells | stem cells | stem cells | cells | cells | genetics | genetics | genome | genome | Dolly | Dolly | clone | clone | regenerative therapy | regenerative therapy | somatic | somatic | SCNT | SCNT | pluripotent | pluripotent | scientific literature | scientific literature | nuclear | nuclear | embryonic | embryonic | adult | adult | epigenetics | epigenetics | methylation | methylation | DNA | DNA | histone | histone | biomedical | biomedical | differentiation | differentiation | epigenome | epigenome | nuclear transfer | nuclear transfer | customized | customized | zygote | zygote | RNA | RNA | cancer | cancer | medicine | medicine

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

9.14 Brain Structure and its Origins (MIT) 9.14 Brain Structure and its Origins (MIT)

Description

This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity. This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Development | Development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Development of the Mammalian Brain (MIT) Development of the Mammalian Brain (MIT)

Description

Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Mammals -- Physiology | Mammals -- Physiology

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.349 Stem Cells: A Cure or Disease? (MIT) 7.349 Stem Cells: A Cure or Disease? (MIT)

Description

Have you ever considered going to a pharmacy to order some new cardiomyocytes (heart muscle cells) for your ailing heart? It might sound crazy, but recent developments in stem cell science have made this concept not so futuristic. In this course, we will explore the underlying biology behind the idea of using stem cells to treat disease, specifically analyzing the mechanisms that enable a single genome to encode multiple cell states ranging from neurons to fibroblasts to T cells. Overall, we hope to provide a comprehensive overview of this exciting new field of research and its clinical relevance. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literat Have you ever considered going to a pharmacy to order some new cardiomyocytes (heart muscle cells) for your ailing heart? It might sound crazy, but recent developments in stem cell science have made this concept not so futuristic. In this course, we will explore the underlying biology behind the idea of using stem cells to treat disease, specifically analyzing the mechanisms that enable a single genome to encode multiple cell states ranging from neurons to fibroblasts to T cells. Overall, we hope to provide a comprehensive overview of this exciting new field of research and its clinical relevance. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literat

Subjects

stem cells | stem cells | stem cell therapy | stem cell therapy | cellular reprogramming | cellular reprogramming | transdifferentiation | transdifferentiation | pluripotency | pluripotency | epigenetics | epigenetics | genome-wide sequencing | genome-wide sequencing | transcription-mediated reprogramming | transcription-mediated reprogramming | embryonic stem cell technology | embryonic stem cell technology | transcription factors | transcription factors | chromatin structure | chromatin structure | H3K4me3 | H3K4me3 | H3K27me3 | H3K27me3 | histone deacetylase 1 | histone deacetylase 1 | RNAi screens | RNAi screens | Oct4 | Oct4 | cloning | cloning | Dolly | Dolly | in vitro differentiation | in vitro differentiation | regenerative medicine | regenerative medicine

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis (MIT) 7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis (MIT)

Description

During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary res During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary res

Subjects

cancer | cancer | embryogenesis | embryogenesis | sonic hedgehog | sonic hedgehog | tumor | tumor | signaling | signaling | proto-oncogene | proto-oncogene | Kras | Kras | apoptosis | apoptosis | self-renewal | self-renewal | regeneration | regeneration | angiogenesis | angiogenesis | VEGF | VEGF | tumorigenesis | tumorigenesis | metastasis | metastasis | microRNA | microRNA

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.342 Developmental and Molecular Biology of Regeneration (MIT) 7.342 Developmental and Molecular Biology of Regeneration (MIT)

Description

How does a regenerating animal "know" what's missing? How are stem cells or differentiated cells used to create new tissues during regeneration? In this class we will take a comparative approach to explore this fascinating problem by critically examining classic and modern scientific literature about the developmental and molecular biology of regeneration. We will learn about conserved developmental pathways that are necessary for regeneration, and we will discuss the relevance of these findings for regenerative medicine. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highl How does a regenerating animal "know" what's missing? How are stem cells or differentiated cells used to create new tissues during regeneration? In this class we will take a comparative approach to explore this fascinating problem by critically examining classic and modern scientific literature about the developmental and molecular biology of regeneration. We will learn about conserved developmental pathways that are necessary for regeneration, and we will discuss the relevance of these findings for regenerative medicine. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highl

Subjects

Regeneration | Regeneration | blastema | blastema | embryo | embryo | progenitor | progenitor | stem cells | stem cells | differentiation | differentiation | dedifferentiation | dedifferentiation | hydra | hydra | morphallaxis | morphallaxis | limb | limb | organ | organ | zebrafish | zebrafish | homeostasis | homeostasis | self-renewal | self-renewal | regenerative medicine | regenerative medicine | differentitate | differentitate | regulate | regulate | salamander | salamander | catenin | catenin | newt | newt | liver | liver | pluriptent | pluriptent | fibroblast | fibroblast

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

12.472 Building Earth-like Planets: From Nebular Gas to Ocean Worlds (MIT) 12.472 Building Earth-like Planets: From Nebular Gas to Ocean Worlds (MIT)

Description

This course covers examination of the state of knowledge of planetary formation, beginning with planetary nebulas and continuing through accretion (from gas, to dust, to planetesimals, to planetary embryos, to planets). It also includes processes of planetary differentiation, crust formation, atmospheric degassing, and surface water condensation. This course has integrated discussions of compositional and physical processes, based upon observations from our solar system and from exoplanets. Focus on terrestrial (rocky and metallic) planets, though more volatile-rich bodies are also examined. This course covers examination of the state of knowledge of planetary formation, beginning with planetary nebulas and continuing through accretion (from gas, to dust, to planetesimals, to planetary embryos, to planets). It also includes processes of planetary differentiation, crust formation, atmospheric degassing, and surface water condensation. This course has integrated discussions of compositional and physical processes, based upon observations from our solar system and from exoplanets. Focus on terrestrial (rocky and metallic) planets, though more volatile-rich bodies are also examined.

Subjects

planets | planets | planetary formation | planetary formation | nebulas | nebulas | planetesimals | planetesimals | embryos | embryos | dust accretion | dust accretion | atmospheric degassing | atmospheric degassing | surface water | surface water | magma ocean processes | magma ocean processes | volatiles | volatiles | habitability | habitability | biosignatures | biosignatures

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-12.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.342 Pluripotent Stem Cells and Genome Engineering for Modeling Human Diseases (MIT) 7.342 Pluripotent Stem Cells and Genome Engineering for Modeling Human Diseases (MIT)

Description

One of the major priorities in biomedical research is understanding the molecular events that establish the complex processes involved in human development and the relationships of these processes to human disease and disease progression. In this class, we will explore stem cell biology and the way in which it has developed and shaped our ability to study complex human disease. We will introduce the field of stem cell biology and genome engineering through critical reading of both the classical and newest primary research literature. In addition, this course will discuss specific disease model systems and their benefits / limitations for understanding the disease and treating human patients. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT One of the major priorities in biomedical research is understanding the molecular events that establish the complex processes involved in human development and the relationships of these processes to human disease and disease progression. In this class, we will explore stem cell biology and the way in which it has developed and shaped our ability to study complex human disease. We will introduce the field of stem cell biology and genome engineering through critical reading of both the classical and newest primary research literature. In addition, this course will discuss specific disease model systems and their benefits / limitations for understanding the disease and treating human patients. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT

Subjects

stem cells | stem cells | genome engineering | genome engineering | pluripotency | pluripotency | disease progression | disease progression | embryonic stem cells | embryonic stem cells | induced pluripotent stem cells | induced pluripotent stem cells | transgenic animals | transgenic animals | regenerative medicine | regenerative medicine | CRISPR/cas9 | CRISPR/cas9 | Nuclear Transfer | Nuclear Transfer | Cellular Reprogramming | Cellular Reprogramming

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.344 Treating Infertility-- From Bench to Bedside and Bedside to Bench (MIT) 7.344 Treating Infertility-- From Bench to Bedside and Bedside to Bench (MIT)

Description

In the western world, approximately 10–15% of couples suffer from subfertility. Consequently, over 5 million babies have been born thanks to assisted reproductive technologies, and more than half of those have been born in the past six years alone. This class will cover the basic biology behind fertility and explore the etiology of infertility. We will highlight open questions in reproductive biology, familiarize students with both tried-and-true and emerging reproductive technologies, and explore the advantages and pitfalls of each. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in In the western world, approximately 10–15% of couples suffer from subfertility. Consequently, over 5 million babies have been born thanks to assisted reproductive technologies, and more than half of those have been born in the past six years alone. This class will cover the basic biology behind fertility and explore the etiology of infertility. We will highlight open questions in reproductive biology, familiarize students with both tried-and-true and emerging reproductive technologies, and explore the advantages and pitfalls of each. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in

Subjects

fertility | fertility | infertility | infertility | assisted reproductive technology | assisted reproductive technology | gonadal stem cells | gonadal stem cells | reproductive biology | reproductive biology | embryo cryopreservation | embryo cryopreservation | oocyte cryopreservation | oocyte cryopreservation | antral follicle counts | antral follicle counts | microdeletions | microdeletions | aneuploidy | aneuploidy | reproductive phenotypes | reproductive phenotypes

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

9.14 Brain Structure and Its Origins (MIT) 9.14 Brain Structure and Its Origins (MIT)

Description

Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections. Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Early development Early development

Description

This free course, Early development, looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy. First published on Thu, 24 Mar 2016 as Early development. To fi This free course, Early development, looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy. First published on Thu, 24 Mar 2016 as Early development. To fi First published on Thu, 24 Mar 2016 as Early development. To find out more visit The Open University's Openlearn website. Creative-Commons 2016 First published on Thu, 24 Mar 2016 as Early development. To find out more visit The Open University's Openlearn website. Creative-Commons 2016

Subjects

Biology | Biology | family | family | contraception | contraception | pregnancies | pregnancies | child development | child development | conception | conception | reproduction | reproduction | poison | poison | Paul Gilroy | Paul Gilroy | news cloud | news cloud | chromosomes | chromosomes | The Sound and the Fury | The Sound and the Fury | hormones | hormones | embryo | embryo | Living with poverty | Living with poverty | development | development | Pussy Riot | Pussy Riot | SK220_1 | SK220_1

License

Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ Creative Commons Attribution-NonCommercial-ShareAlike 2.0 Licence Licensed under a Creative Commons Attribution - NonCommercial-ShareAlike 2.0 Licence - see http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ - Original copyright The Open University

Site sourced from

http://www.open.edu/openlearn/rss/try-content

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.344 The Fountain of Life: From Dolly to Customized Embryonic Stem Cells (MIT)

Description

During development, the genetic content of each cell remains, with a few exceptions, identical to that of the zygote. Most differentiated cells therefore retain all of the genetic information necessary to generate an entire organism. It was through pioneering technology of somatic cell nuclear transfer (SCNT) that this concept was experimentally proven. Only 10 years ago the sheep Dolly was the first mammal to be cloned from an adult organism, demonstrating that the differentiated state of a mammalian cell can be fully reversible to a pluripotent embryonic state. A key conclusion from these experiments was that the difference between pluripotent cells such as embryonic stem (ES) cells and unipotent differentiated cells is solely a consequence of reversible changes. These changes, which hav

Subjects

embryonic stem cells | stem cells | cells | genetics | genome | Dolly | clone | regenerative therapy | somatic | SCNT | pluripotent | scientific literature | nuclear | embryonic | adult | epigenetics | methylation | DNA | histone | biomedical | differentiation | epigenome | nuclear transfer | customized | zygote | RNA | cancer | medicine

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-alllifesciencescourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

9.14 Brain Structure and Its Origins (MIT)

Description

Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections.

Subjects

CNS structures | development | plasticity | anatomy | tissue culture | embryogenesis | PNS anatomy and development | process outgrowth | synaptogenesis | growth factors | cell survival | spinal and hindbrain anatomy | comparative anatomy | CNS evolution | trigeminal system | retinotectal system | regeneration | neocortex anatomy | olfactory system | corpus striatum | brain transplants | limbic system

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-alllifesciencescourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

A01 The Esophagus - Embryology

Description

Authors:  Dr Juan H Klopper Lecture series in acute care surgery. Clicked 42 times. Last clicked 09/12/2014 - 12:09. Teaching & Learning Context:  Managing acute care surgical conditions.

Subjects

Health Sciences | Surgery | Video | Video Lectures | English | Post-secondary | embryology | esophagus | oesophagus | operative surgery | surgery

License

http://creativecommons.org/licenses/by-nc-sa/2.5/za/

Site sourced from

http://opencontent.uct.ac.za/recent-posts/feed.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Early development

Description

This unit looks at the human being in the context of an individual life cycle, examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception, and about contraception to the present day, we look at the cells involved in the conception and development of a new individual. Gamete production (that is, production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and, when things go wrong, infertility is explained. We then discuss the early development of a new individual, along with some thoughts on women's experience of pregnancy.

Subjects

science and nature | abortion | birth_rate | child_development | chromosomes | conception | contraception | development | embryo | family | fertilization | gametes | hormones | infertility | lifecycle | meiosis | ovulation | pregnancy | reproduction | sex_selection | Education | X000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Rabbit Embryo (Digital SlideBox)

Description

Interactive histology image of a rabbit embryo. Longitudinal section at 20 days.

Subjects

ukoer | ooer | medev | rabbit | embryo | veterinary medicine | histology | slide | microscopy | specialist | toolkit v1 | rvc | related subjects | D000

License

Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-nd/2.0/uk/ http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Curated collection of Physiology resources

Description

This is an evaluated collection of links to resources for learning and teaching subjects relating to Physiology. This forms part of the UK Centre for Bioscience OeRBITAL project.

Subjects

ukoer | oerbital | physiology | anatomy | cardiovascular | renal | respiratory | human embryo | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Developmental Biology

Description

In this course, the student will learn about the field of developmental biology from its origins to the present day. The course will take a look at historical experiments as well as modern techniques and the mechanisms of development. The student will follow a variety of metazoan organisms from their start at fertilization through the stages of their development and on to entire organismal and post-embryonic development, learning along the way about the molecular and genetic regulations involved in these processes. This free course may be completed online at any time. See course site for detailed overview and learning outcomes. (Biology 310)

Subjects

biology | development | developmental biology | genes | cleavage | gastrulation | embryonic development | evolution | gametogenesis | fertilization | expression | axis formation | evo-devo | Biological sciences | C000

License

Attribution 2.0 UK: England & Wales Attribution 2.0 UK: England & Wales http://creativecommons.org/licenses/by/2.0/uk/ http://creativecommons.org/licenses/by/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

The ethics of displaying animal and human remains in museums (web link)

Description

This resource has been created as part of the JISC funded project Object Based Learning for Higher Education (OBL4HE) - a project to create a range of online educational resources for university teachers and students based around the use of museum collections and archival material for enhancing learning. To search for more of the resources created in this project, please search for the key word OBL4HE.

Subjects

museum ethics | embryo | skeleton | zoology | display | Museum Studies | museum | OBL4HE | EDUCATION / TRAINING / TEACHING | G

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

The ethics of displaying animal and human remains in museums (files)

Description

This resource has been created as part of the JISC funded project Object Based Learning for Higher Education (OBL4HE) - a project to create a range of online educational resources for university teachers and students based around the use of museum collections and archival material for enhancing learning. To search for more of the resources created in this project, please search for the key word OBL4HE.

Subjects

museum ethics | embryo | skeleton | zoology | display | Museum Studies | museum | OBL4HE | EDUCATION / TRAINING / TEACHING | G

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Site sourced from

http://dspace.jorum.ac.uk/oai/request?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Early development

Description

This free course looks at the human being in the context of an individual life cycle examining some of the processes that contribute to the formation of a new person. After a brief discussion of historical ideas about human conception and about contraception to the present day we look at the cells involved in the conception and development of a new individual. Gamete production (that is production of mature cells able to unite with another in sexual reproduction) in both men and women is introduced and the role gametes in fertility and when things go wrong infertility is explained. We then discuss the early development of a new individual

Subjects

Biology | family | contraception | pregnancies | child development | conception | reproduction | poison | Paul Gilroy | news cloud | chromosomes | The Sound and the Fury | hormones | embryo | Living with poverty | development | Pussy Riot | SK220_1

License

Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0 Except for third party materials and otherwise stated in the acknowledgement section (see our terms and conditions http://www.open.ac.uk/conditions) this content is made available under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Licence. - http://creativecommons.org/licenses/by-nc-sa/4.0

Site sourced from

http://www.open.edu/openlearn/feeds/oai?verb=ListRecords&metadataPrefix=oai_dc

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

9.14 Brain Structure and Its Origins (MIT)

Description

Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections.

Subjects

CNS structures | development | plasticity | anatomy | tissue culture | embryogenesis | PNS anatomy and development | process outgrowth | synaptogenesis | growth factors | cell survival | spinal and hindbrain anatomy | comparative anatomy | CNS evolution | trigeminal system | retinotectal system | regeneration | neocortex anatomy | olfactory system | corpus striatum | brain transplants | limbic system

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

9.14 Brain Structure and its Origins (MIT)

Description

This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity.

Subjects

CNS structures | development | plasticity | anatomy | tissue culture | embryogenesis | PNS anatomy and development | process outgrowth | synaptogenesis | growth factors | cell survival | spinal and hindbrain anatomy | comparative anatomy | CNS evolution | trigeminal system | retinotectal system | regeneration | neocortex anatomy | olfactory system | corpus striatum | brain transplants | limbic system | Development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Development of the Mammalian Brain (MIT)

Description

Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play

Subjects

CNS structures | development | plasticity | anatomy | tissue culture | embryogenesis | PNS anatomy and development | process outgrowth | synaptogenesis | growth factors | cell survival | spinal and hindbrain anatomy | comparative anatomy | CNS evolution | trigeminal system | retinotectal system | regeneration | neocortex anatomy | olfactory system | corpus striatum | brain transplants | limbic system | Mammals -- Physiology

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.344 Treating Infertility-- From Bench to Bedside and Bedside to Bench (MIT)

Description

In the western world, approximately 10–15% of couples suffer from subfertility. Consequently, over 5 million babies have been born thanks to assisted reproductive technologies, and more than half of those have been born in the past six years alone. This class will cover the basic biology behind fertility and explore the etiology of infertility. We will highlight open questions in reproductive biology, familiarize students with both tried-and-true and emerging reproductive technologies, and explore the advantages and pitfalls of each. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in

Subjects

fertility | infertility | assisted reproductive technology | gonadal stem cells | reproductive biology | embryo cryopreservation | oocyte cryopreservation | antral follicle counts | microdeletions | aneuploidy | reproductive phenotypes

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata