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ón ón

Description

El curso trata sobre los análisis de imágenes a través de computadores que se están implantando en la industria con el fin de lograr una mayor interactuación entre las máquinas y el entorno que las rodea y de conseguir un control de calidad total de los productos fabricados. Para ello se revisan los tipos básicos de elementos y sensores, viéndose las ventajas e inconvenientes de cada uno de ellos, así como las técnicas más usuales de procesar la información que proveen y se presentan diversos métodos para el reconocimiento de patrones. El curso trata sobre los análisis de imágenes a través de computadores que se están implantando en la industria con el fin de lograr una mayor interactuación entre las máquinas y el entorno que las rodea y de conseguir un control de calidad total de los productos fabricados. Para ello se revisan los tipos básicos de elementos y sensores, viéndose las ventajas e inconvenientes de cada uno de ellos, así como las técnicas más usuales de procesar la información que proveen y se presentan diversos métodos para el reconocimiento de patrones.

Subjects

ón de características | ón de características | áster | áster | ón por computador | ón por computador | ágenes digitales | ágenes digitales | Reconocimiento de objetos | Reconocimiento de objetos | ón de imágenes | ón de imágenes | ágenes | ágenes | ógicas y descripción de objetos | ógicas y descripción de objetos | ía de Sistemas y Automática | ía de Sistemas y Automática | 2010 | 2010 | áticos | áticos | ía Industrial | ía Industrial

License

Copyright 2015, UC3M http://creativecommons.org/licenses/by-nc-sa/4.0/

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7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis (MIT) 7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis (MIT)

Description

During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary res During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary res

Subjects

cancer | cancer | embryogenesis | embryogenesis | sonic hedgehog | sonic hedgehog | tumor | tumor | signaling | signaling | proto-oncogene | proto-oncogene | Kras | Kras | apoptosis | apoptosis | self-renewal | self-renewal | regeneration | regeneration | angiogenesis | angiogenesis | VEGF | VEGF | tumorigenesis | tumorigenesis | metastasis | metastasis | microRNA | microRNA

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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9.14 Brain Structure and its Origins (MIT) 9.14 Brain Structure and its Origins (MIT)

Description

This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity. This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Development | Development

License

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Development of the Mammalian Brain (MIT) Development of the Mammalian Brain (MIT)

Description

Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Mammals -- Physiology | Mammals -- Physiology

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Communication (MIT) Communication (MIT)

Description

This introductory biology laboratory course covers the application of experimental techniques in microbiology, biochemistry, cell and developmental biology. Emphasis is placed on the integration of factual knowledge with understanding of the design of the experiments and data analysis in order to prepare the students for future research projects. Development of skills critical for writing about scientific findings in modern biology is also covered in the Scientific Communications portion of the curriculum, 7.02CI. Additional Faculty Dr. Katherine Bacon Schneider Dr. Jean-Francois Hamel Ms. Deborah Kruzel Dr. Megan Rokop This introductory biology laboratory course covers the application of experimental techniques in microbiology, biochemistry, cell and developmental biology. Emphasis is placed on the integration of factual knowledge with understanding of the design of the experiments and data analysis in order to prepare the students for future research projects. Development of skills critical for writing about scientific findings in modern biology is also covered in the Scientific Communications portion of the curriculum, 7.02CI. Additional Faculty Dr. Katherine Bacon Schneider Dr. Jean-Francois Hamel Ms. Deborah Kruzel Dr. Megan Rokop

Subjects

experimental biology | experimental biology | microbial genetics | microbial genetics | protein biochemistry | protein biochemistry | recombinant DNA | recombinant DNA | development | development | zebrafish | zebrafish | phase contrast microscopy | phase contrast microscopy | teratogenesis | teratogenesis | rna isolation | rna isolation | northern blot | northern blot | gene expression | gene expression | western blot | western blot | PCR | PCR | polymerase chain reaction | polymerase chain reaction | RNA gel | RNA gel | RNA fixation | RNA fixation | probe labeling | probe labeling | mutagenesis | mutagenesis | transposon | transposon | column chromatography | column chromatography | size-exclusion chromatography | size-exclusion chromatography | anion exchange chromatography | anion exchange chromatography | SDS-Page gel | SDS-Page gel | enzyme kinetics | enzyme kinetics | transformation | transformation | primers | primers

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.13 Experimental Microbial Genetics (MIT) 7.13 Experimental Microbial Genetics (MIT)

Description

In this class, students engage in independent research projects to probe various aspects of the physiology of the bacterium Pseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials In this class, students engage in independent research projects to probe various aspects of the physiology of the bacterium Pseudomonas aeruginosa PA14, an opportunistic pathogen isolated from the lungs of cystic fibrosis patients. Students use molecular genetics to examine survival in stationary phase, antibiotic resistance, phase variation, toxin production, and secondary metabolite production. Projects aim to discover the molecular basis for these processes using both classical and cutting-edge techniques. These include plasmid manipulation, genetic complementation, mutagenesis, PCR, DNA sequencing, enzyme assays, and gene expression studies. Instruction and practice in written and oral communication are also emphasized. WARNING NOTICE The experiments described in these materials

Subjects

microbiology | microbiology | genetics | genetics | pseudomonas | pseudomonas | bacteria | bacteria | genes | genes | pathogen | pathogen | mutagenesis | mutagenesis | PCR | PCR | DNA sequencing | DNA sequencing | enzyme assays | enzyme assays | gene expression | gene expression | molecular genetics | molecular genetics | plasmid manipulation | plasmid manipulation | genetic complementation | genetic complementation | laboratory | laboratory | protocol | protocol | vector | vector | mutant | mutant | cystic fibrosis | cystic fibrosis

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.340 Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer (MIT) 7.340 Avoiding Genomic Instability: DNA Replication, the Cell Cycle, and Cancer (MIT)

Description

In this class we will learn about how the process of DNA replication is regulated throughout the cell cycle and what happens when DNA replication goes awry. How does the cell know when and where to begin replicating its DNA? How does a cell prevent its DNA from being replicated more than once? How does damaged DNA cause the cell to arrest DNA replication until that damage has been repaired? And how is the duplication of the genome coordinated with other essential processes? We will examine both classical and current papers from the scientific literature to provide answers to these questions and to gain insights into how biologists have approached such problems. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored f In this class we will learn about how the process of DNA replication is regulated throughout the cell cycle and what happens when DNA replication goes awry. How does the cell know when and where to begin replicating its DNA? How does a cell prevent its DNA from being replicated more than once? How does damaged DNA cause the cell to arrest DNA replication until that damage has been repaired? And how is the duplication of the genome coordinated with other essential processes? We will examine both classical and current papers from the scientific literature to provide answers to these questions and to gain insights into how biologists have approached such problems. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored f

Subjects

cell | cell | genetic material | genetic material | cell death | cell death | tumorigenesis | tumorigenesis | mutations | mutations | genes | genes | DNA replication | DNA replication | cell cycle | cell cycle | damaged DNA | damaged DNA | genome | genome | tumor formation | tumor formation | anti-cancer drugs | anti-cancer drugs | viruses | viruses | cellular controls | cellular controls

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.22 Developmental Biology (MIT) 7.22 Developmental Biology (MIT)

Description

This graduate and advanced undergraduate level lecture and literature discussion course covers the current understanding of the molecular mechanisms that regulate animal development. Evolutionary mechanisms are emphasized as well as the discussion of relevant diseases. Vertebrate (mouse, chick, frog, fish) and invertebrate (fly, worm) models are covered. Specific topics include formation of early body plan, cell type determination, organogenesis, morphogenesis, stem cells, cloning, and issues in human development. This graduate and advanced undergraduate level lecture and literature discussion course covers the current understanding of the molecular mechanisms that regulate animal development. Evolutionary mechanisms are emphasized as well as the discussion of relevant diseases. Vertebrate (mouse, chick, frog, fish) and invertebrate (fly, worm) models are covered. Specific topics include formation of early body plan, cell type determination, organogenesis, morphogenesis, stem cells, cloning, and issues in human development.

Subjects

animal development | animal development | developmental biology | developmental biology | evolution | evolution | formation of early body plan | formation of early body plan | cell type determination | cell type determination | organogenesis | organogenesis | morphogenesis | morphogenesis | stem cells | stem cells | cloning | cloning | human development | human development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.342 Cancer Biology: From Basic Research to the Clinic (MIT) 7.342 Cancer Biology: From Basic Research to the Clinic (MIT)

Description

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. In 1971, President Nixon declared the "War on Cancer," but after three decades the war is still raging. How much progress have we made toward winning the war and what are we doing to improve the fight? Understanding the molecular and cellular events involved in tumor formation, progression, and metastasis is crucial to the development of innovative therapy for cancer patients. Insights into these processes have been gleaned through basic research using biochemical, molecular, and genetic ana This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. In 1971, President Nixon declared the "War on Cancer," but after three decades the war is still raging. How much progress have we made toward winning the war and what are we doing to improve the fight? Understanding the molecular and cellular events involved in tumor formation, progression, and metastasis is crucial to the development of innovative therapy for cancer patients. Insights into these processes have been gleaned through basic research using biochemical, molecular, and genetic ana

Subjects

cancer | cancer | tumor | tumor | metastasis | metastasis | genetic analysis | genetic analysis | cancer biology | cancer biology | model organisms | model organisms | genetic pathways | genetic pathways | uncontrolled growth | uncontrolled growth | tumor suppressor genes | tumor suppressor genes | oncogenes | oncogenes | tumor initiation | tumor initiation | cell cycle | cell cycle | chromosomal aberration | chromosomal aberration | apoptosis | apoptosis | cell death | cell death | signal transduction pathways | signal transduction pathways | proto-oncogene | proto-oncogene | mutation | mutation | DNA mismatch repair | DNA mismatch repair | telomeres | telomeres | mouse models | mouse models | tissue specificity | tissue specificity | malignancy | malignancy | stem cells | stem cells | therapeutic resistance | therapeutic resistance | differentiation | differentiation | caner research | caner research | cancer therapeutics | cancer therapeutics | chemotherapy | chemotherapy

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.13 Experimental Microbial Genetics (MIT) 7.13 Experimental Microbial Genetics (MIT)

Description

Also referred to as the Microbial Genetics Project Lab, this is a hands-on research course designed to introduce the student to the strategies and challenges associated with microbiology research. Students take on independent and original research projects that are designed to be instructive with the goal of advancing a specific field of research in microbiology. Also referred to as the Microbial Genetics Project Lab, this is a hands-on research course designed to introduce the student to the strategies and challenges associated with microbiology research. Students take on independent and original research projects that are designed to be instructive with the goal of advancing a specific field of research in microbiology.

Subjects

microbiology | microbiology | genetics | genetics | rhodococcus | rhodococcus | bacteria | bacteria | genes | genes | plasmid manipulation | plasmid manipulation | mutagenesis | mutagenesis | PCR | PCR | DNA sequencing | DNA sequencing | enzyme assays | enzyme assays | gene expression | gene expression | molecular genetics | molecular genetics | Gram-positive | Gram-positive | gram-negative | gram-negative | bioconversion processes | bioconversion processes | synthesis | synthesis | precursors | precursors | metabolites | metabolites | genetic complementation | genetic complementation | laboratory | laboratory | lab | lab

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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HST.525J Tumor Pathophysiology and Transport Phenomena (MIT) HST.525J Tumor Pathophysiology and Transport Phenomena (MIT)

Description

Tumor pathophysiology plays a central role in the growth, invasion, metastasis and treatment of solid tumors. This class applies principles of transport phenomena to develop a systems-level, quantitative understanding of angiogenesis, blood flow and microcirculation, metabolism and microenvironment, transport and binding of small and large molecules, movement of cancer and immune cells, metastatic process, and treatment response. Additional Faculty Dr. Pat D'Amore Dr. Dan Duda Dr. Robert Langer Prof. Robert Weinberg Dr. Marsha Moses Dr. Raghu Kalluri Dr. Lance Munn Tumor pathophysiology plays a central role in the growth, invasion, metastasis and treatment of solid tumors. This class applies principles of transport phenomena to develop a systems-level, quantitative understanding of angiogenesis, blood flow and microcirculation, metabolism and microenvironment, transport and binding of small and large molecules, movement of cancer and immune cells, metastatic process, and treatment response. Additional Faculty Dr. Pat D'Amore Dr. Dan Duda Dr. Robert Langer Prof. Robert Weinberg Dr. Marsha Moses Dr. Raghu Kalluri Dr. Lance Munn

Subjects

HST.525 | HST.525 | 10.548 | 10.548 | tumor | tumor | cancer | cancer | tumor vasculature | tumor vasculature | antiangiogenesis | antiangiogenesis | bone marrow-derived stem cells | bone marrow-derived stem cells | BMDC | BMDC | stem cell research | stem cell research | experimental cancer therapy | experimental cancer therapy | cancer research | cancer research | tumor-host interactions | tumor-host interactions | vascular normalization | vascular normalization | vascular transport | vascular transport | interstitial transport | interstitial transport | lymphatic transport | lymphatic transport | microcirculation | microcirculation | molecular therapeutics | molecular therapeutics | blood vessels | blood vessels | angiogenesis | angiogenesis | drug delivery | drug delivery | intravital microscopy | intravital microscopy

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.13 Experimental Microbial Genetics (MIT) 7.13 Experimental Microbial Genetics (MIT)

Description

Also referred to as the Microbial Genetics Project Lab, this is a hands-on research course designed to introduce the student to the strategies and challenges associated with microbiology research. Students take on independent and original research projects that are designed to be instructive with the goal of advancing a specific field of research in microbiology. Also referred to as the Microbial Genetics Project Lab, this is a hands-on research course designed to introduce the student to the strategies and challenges associated with microbiology research. Students take on independent and original research projects that are designed to be instructive with the goal of advancing a specific field of research in microbiology.

Subjects

microbiology | microbiology | genetics | genetics | rhodococcus | rhodococcus | bacteria | bacteria | genes | genes | plasmid manipulation | plasmid manipulation | mutagenesis | mutagenesis | PCR | PCR | DNA sequencing | DNA sequencing | enzyme assays | enzyme assays | gene expression | gene expression | molecular genetics | molecular genetics | Gram-positive | Gram-positive | gram-negative | gram-negative | bioconversion processes | bioconversion processes | synthesis | synthesis | precursors | precursors | metabolites | metabolites | genetic complementation | genetic complementation | laboratory | laboratory | lab | lab

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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9.14 Brain Structure and Its Origins (MIT) 9.14 Brain Structure and Its Origins (MIT)

Description

Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections. Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.343 When Development Goes Awry: How Cancer Co-opts Mechanisms of Embryogensis (MIT)

Description

During this course, we will study the similarities between cancer and normal development to understand how tumors co-opt normal developmental processes to facilitate cancer initiation, maintenance and progression. We will examine critical signaling pathways that govern these processes and, importantly, how some of these pathways hold promise as therapeutic targets for cancer treatment. We will discuss how future treatments might be personalized to target cancer cells in specific patients. We will also consider examples of newly-approved drugs that have dramatically helped patients combat this devastating disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary res

Subjects

cancer | embryogenesis | sonic hedgehog | tumor | signaling | proto-oncogene | Kras | apoptosis | self-renewal | regeneration | angiogenesis | VEGF | tumorigenesis | metastasis | microRNA

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Historia del Constitucionalismo Americano Historia del Constitucionalismo Americano

Description

A través de siete temas y de manera sintética, se hace un recorrido por los momentos más importantes en la construcción y desarrollo del constitucionalismo americano, identificándose así etapas que permite una compresión más ágil. Se ofrecen los documentos clave de este proceso para que el lector pueda contrastar y reflexionar sobre las cuestiones propuestas. A través de siete temas y de manera sintética, se hace un recorrido por los momentos más importantes en la construcción y desarrollo del constitucionalismo americano, identificándose así etapas que permite una compresión más ágil. Se ofrecen los documentos clave de este proceso para que el lector pueda contrastar y reflexionar sobre las cuestiones propuestas.

Subjects

New Deal | New Deal | Historia de America | Historia de America | ón | ón | Guerra Civil | Guerra Civil | Época de la Reconstrucción | Época de la Reconstrucción | Constituciones revolucionarias | Constituciones revolucionarias | Historia del Derecho y de las Instituciones | Historia del Derecho y de las Instituciones | Derechos Civiles | Derechos Civiles | Constitucionalismo norteamericano | Constitucionalismo norteamericano | ígenes coloniales | ígenes coloniales | Época Progresista | Época Progresista | Grado en Derecho | Grado en Derecho | 2011 | 2011

License

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9.322J Genetic Neurobiology (MIT) 9.322J Genetic Neurobiology (MIT)

Description

Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans. Deals with the specific functions of neurons, the interactions of neurons in development, and the organization of neuronal ensembles to produce behavior, by functional analysis of mutations and molecular analysis of their genes. Concentrates on work with nematodes, fruit flies, mice, and humans.

Subjects

functions of neurons | functions of neurons | interactions of neurons | interactions of neurons | development | development | organization | organization | behavior | behavior | functional analysis of mutations | functional analysis of mutations | molecular analysis of genes | molecular analysis of genes | nematodes | nematodes | fruit flies | fruit flies | humans | humans | 9.322 | 9.322

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.03 Genetics (MIT) 7.03 Genetics (MIT)

Description

The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease. The principles of genetics with application to the study of biological function at the level of molecules, cells, and multicellular organisms, including humans. Structure and function of genes, chromosomes and genomes. Biological variation resulting from recombination, mutation, and selection. Population genetics. Use of genetic methods to analyze protein function, gene regulation and inherited disease.

Subjects

Population genetics | Population genetics | selection | selection | mutation | mutation | recombination | recombination | genomes | genomes | chromosomes | chromosomes | genes | genes

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8.592 Statistical Physics in Biology (MIT) 8.592 Statistical Physics in Biology (MIT)

Description

Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; Considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.Technical RequirementsAny number of biological sequence comparison software tools can be used to import the .fna files found on this course site. Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; Considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.Technical RequirementsAny number of biological sequence comparison software tools can be used to import the .fna files found on this course site.

Subjects

Bioinformatics | Bioinformatics | DNA | DNA | gene finding | gene finding | sequence comparison | sequence comparison | phylogenetic trees | phylogenetic trees | biopolymers | biopolymers | DNA double helix | DNA double helix | secondary structure of RNA | secondary structure of RNA | protein folding | protein folding | protein motors | membranes | protein motors | membranes | cellular networks | cellular networks | neural networks | neural networks | evolution | evolution | statistical physics | statistical physics | molecular biology | molecular biology | deoxyribonucleic acid | deoxyribonucleic acid | genes | genes | genetics | genetics | gene sequencing | gene sequencing | phylogenetics | phylogenetics | double helix | double helix | RNA | RNA | ribonucleic acid | ribonucleic acid | force | force | motion | motion | packaging | packaging | protein motors | protein motors | membranes | membranes | biochemistry | biochemistry | genome | genome | optimization | optimization | partitioning | partitioning | pattern recognition | pattern recognition | collective behavior | collective behavior

License

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Languages disorders in children: What can they tell us about genes and brains?

Description

Recent studies have shown that genes are strongly implicated in determining if children will develop language disorders. In this talk, Professor Bishop examines the role genetics play in language development and language disorders. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

development | genetics | language | genes | alumni | children | development | genetics | language | genes | alumni | children | 2009-09-25

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Languages disorders in children: What can they tell us about genes and brains?

Description

Recent studies have shown that genes are strongly implicated in determining if children will develop language disorders. In this talk, Professor Bishop examines the role genetics play in language development and language disorders. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

development | genetics | language | genes | alumni | children | development | genetics | language | genes | alumni | children | 2009-09-25

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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The Role of Genes in Bipolar Disorder: Recent Findings and What They Mean. Monica Fooks Memorial Lecture

Description

Professor Paul Harrison, Head of Translational Neurobiology Research Group, Oxford, gives the 2012 Monica Fooks memorial lecture on recent findings in bipolar disorder. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

genes | genetics | psychology | somerville college | bipolar disorder | psychiatry | manic depression | monica fooks | fooks | genes | genetics | psychology | somerville college | bipolar disorder | psychiatry | manic depression | monica fooks | fooks | 2012-11-16

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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The Role of Genes in Bipolar Disorder: Recent Findings and What They Mean. Monica Fooks Memorial Lecture

Description

Professor Paul Harrison, Head of Translational Neurobiology Research Group, Oxford, gives the 2012 Monica Fooks memorial lecture on recent findings in bipolar disorder. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

genes | genetics | psychology | somerville college | bipolar disorder | psychiatry | manic depression | monica fooks | fooks | genes | genetics | psychology | somerville college | bipolar disorder | psychiatry | manic depression | monica fooks | fooks | 2012-11-16

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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7.01SC Fundamentals of Biology (MIT) 7.01SC Fundamentals of Biology (MIT)

Description

Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality. Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality.

Subjects

amino acids | amino acids | carboxyl group | carboxyl group | amino group | amino group | side chains | side chains | polar | polar | hydrophobic | hydrophobic | primary structure | primary structure | secondary structure | secondary structure | tertiary structure | tertiary structure | quaternary structure | quaternary structure | x-ray crystallography | x-ray crystallography | alpha helix | alpha helix | beta sheet | beta sheet | ionic bond | ionic bond | non-polar bond | non-polar bond | van der Waals interactions | van der Waals interactions | proton gradient | proton gradient | cyclic photophosphorylation | cyclic photophosphorylation | sunlight | sunlight | ATP | ATP | chlorophyll | chlorophyll | chlorophyll a | chlorophyll a | electrons | electrons | hydrogen sulfide | hydrogen sulfide | biosynthesis | biosynthesis | non-cyclic photophosphorylation | non-cyclic photophosphorylation | photosystem II | photosystem II | photosystem I | photosystem I | cyanobacteria | cyanobacteria | chloroplast | chloroplast | stroma | stroma | thylakoid membrane | thylakoid membrane | Genetics | Genetics | Mendel | Mendel | Mendel's Laws | Mendel's Laws | cloning | cloning | restriction enzymes | restriction enzymes | vector | vector | insert DNA | insert DNA | ligase | ligase | library | library | E.Coli | E.Coli | phosphatase | phosphatase | yeast | yeast | transformation | transformation | ARG1 gene | ARG1 gene | ARG1 mutant yeast | ARG1 mutant yeast | yeast wild-type | yeast wild-type | cloning by complementation | cloning by complementation | Human Beta Globin gene | Human Beta Globin gene | protein tetramer | protein tetramer | vectors | vectors | antibodies | antibodies | human promoter | human promoter | splicing | splicing | mRNA | mRNA | cDNA | cDNA | reverse transcriptase | reverse transcriptase | plasmid | plasmid | electrophoresis | electrophoresis | DNA sequencing | DNA sequencing | primer | primer | template | template | capillary tube | capillary tube | laser detector | laser detector | human genome project | human genome project | recombinant DNA | recombinant DNA | clone | clone | primer walking | primer walking | subcloning | subcloning | computer assembly | computer assembly | shotgun sequencing | shotgun sequencing | open reading frame | open reading frame | databases | databases | polymerase chain reaction (PCR) | polymerase chain reaction (PCR) | polymerase | polymerase | nucleotides | nucleotides | Thermus aquaticus | Thermus aquaticus | Taq polymerase | Taq polymerase | thermocycler | thermocycler | resequencing | resequencing | in vitro fertilization | in vitro fertilization | pre-implantation diagnostics | pre-implantation diagnostics | forensics | forensics | genetic engineering | genetic engineering | DNA sequences | DNA sequences | therapeutic proteins | therapeutic proteins | E. coli | E. coli | disease-causing mutations | disease-causing mutations | cleavage of DNA | cleavage of DNA | bacterial transformation | bacterial transformation | recombinant DNA revolution | recombinant DNA revolution | biotechnology industry | biotechnology industry | Robert Swanson | Robert Swanson | toxin gene | toxin gene | pathogenic bacterium | pathogenic bacterium | biomedical research | biomedical research | S. Pyogenes | S. Pyogenes | origin of replication | origin of replication

License

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9.14 Brain Structure and Its Origins (MIT)

Description

Outline of mammalian functional neuroanatomy, aided by studies of comparative neuroanatomy and evolution, and of brain development. Topics include early steps to a central nervous system, basic patterns of brain and spinal cord connections, regional development and differentiation, regeneration, motor and sensory pathways and structures, systems underlying motivations, innate action patterns, formation of habits, and various cognitive functions. Lab techniques reviewed. Optional brain dissections.

Subjects

CNS structures | development | plasticity | anatomy | tissue culture | embryogenesis | PNS anatomy and development | process outgrowth | synaptogenesis | growth factors | cell survival | spinal and hindbrain anatomy | comparative anatomy | CNS evolution | trigeminal system | retinotectal system | regeneration | neocortex anatomy | olfactory system | corpus striatum | brain transplants | limbic system

License

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7.340 Unusual Biology: The Science of Emerging Pathogens (MIT) 7.340 Unusual Biology: The Science of Emerging Pathogens (MIT)

Description

Infectious diseases represent a serious global public health problem. They have the potential to kill millions of people, whether they emerge naturally as outbreaks or pandemics, or deliberately through bioterrorism. Some examples of diseases caused by emerging pathogens are the Bubonic Plague, Toxoplasmosis, African Sleeping Sickness, and Chagas Disease. Each day, infectious disease scientists serve on the front lines protecting us from such threats. In this course students will learn how to design and critique experiments through the discussion of primary research articles that explore the molecular basis of disease caused by emerging pathogens. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students w Infectious diseases represent a serious global public health problem. They have the potential to kill millions of people, whether they emerge naturally as outbreaks or pandemics, or deliberately through bioterrorism. Some examples of diseases caused by emerging pathogens are the Bubonic Plague, Toxoplasmosis, African Sleeping Sickness, and Chagas Disease. Each day, infectious disease scientists serve on the front lines protecting us from such threats. In this course students will learn how to design and critique experiments through the discussion of primary research articles that explore the molecular basis of disease caused by emerging pathogens. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students w

Subjects

pathogens | pathogens | Infectious diseases | Infectious diseases | parasite | parasite | host cell | host cell | gene expression | gene expression | Toxoplasma rhoptry protein 16 (ROP16) | Toxoplasma rhoptry protein 16 (ROP16) | Toxoplasma gondii | Toxoplasma gondii | STAT6 | STAT6 | Plasmodium falciparum | Plasmodium falciparum | malaria | malaria | RON8 | RON8 | Trypanosoma cruzi | Trypanosoma cruzi | Chagas disease | Chagas disease | Listeria monocytogenes | Listeria monocytogenes | Leishmaniasis | Leishmaniasis | Francisella | Francisella | pathogen proliferation | pathogen proliferation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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