Description

This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials.Technical RequirementsMATLAB® software is required to run the .m and .fig files found on this course site. This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials.Technical RequirementsMATLAB® software is required to run the .m and .fig files found on this course site.

Subjects

physical chemistry of biological systems | physical chemistry of biological systems | macroscopic thermodynamic properties | macroscopic thermodynamic properties | microscopic molecular properties | microscopic molecular properties | statistical mechanics | statistical mechanics | chemical potentials | chemical potentials | equilibrium states | equilibrium states | binding cooperativity | binding cooperativity | behavior of macromolecules in solution and at interfaces | behavior of macromolecules in solution and at interfaces | solvation | solvation | protein structure | protein structure | genomic analysis | genomic analysis | single molecule biomechanics | single molecule biomechanics | biomaterials | biomaterials | 2.772J | 2.772J | BE.011 | BE.011 | 2.772 | 2.772

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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http://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

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Description

In this course, we will survey the primary systems biology literature, particularly as it pertains to understanding and treating various forms of cancer. We will consider various computational and experimental techniques being used in the field of systems biology, focusing on how systems principles have helped advance biological understanding. We will also discuss the application of the principles of systems biology and network biology to drug development, an emerging discipline called "network medicine." This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive sett In this course, we will survey the primary systems biology literature, particularly as it pertains to understanding and treating various forms of cancer. We will consider various computational and experimental techniques being used in the field of systems biology, focusing on how systems principles have helped advance biological understanding. We will also discuss the application of the principles of systems biology and network biology to drug development, an emerging discipline called "network medicine." This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive sett

Subjects

systems biology | systems biology | network medicine | network medicine | cancer | cancer | cancer therapeutics | cancer therapeutics | quantitative high-throughput data acquisition | quantitative high-throughput data acquisition | genomic analysis | genomic analysis | signaling network biology | signaling network biology | statistical/computational modeling | statistical/computational modeling | network biology | network biology | drug development | drug development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

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Description

This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials. This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials.

Subjects

physical chemistry of biological systems | physical chemistry of biological systems | macroscopic thermodynamic properties | macroscopic thermodynamic properties | microscopic molecular properties | microscopic molecular properties | statistical mechanics | statistical mechanics | chemical potentials | chemical potentials | equilibrium states | equilibrium states | binding cooperativity | binding cooperativity | behavior of macromolecules in solution and at interfaces | behavior of macromolecules in solution and at interfaces | solvation | solvation | protein structure | protein structure | genomic analysis | genomic analysis | single molecule biomechanics | single molecule biomechanics | biomaterials | biomaterials | BE.011J | BE.011J | BE.011 | BE.011 | 2.772 | 2.772

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-alllifesciencescourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

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Description

This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials.Technical RequirementsMATLAB® software is required to run the .m and .fig files found on this course site.

Subjects

physical chemistry of biological systems | macroscopic thermodynamic properties | microscopic molecular properties | statistical mechanics | chemical potentials | equilibrium states | binding cooperativity | behavior of macromolecules in solution and at interfaces | solvation | protein structure | genomic analysis | single molecule biomechanics | biomaterials | 2.772J | BE.011 | 2.772

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allarchivedcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

Description

In this course, we will survey the primary systems biology literature, particularly as it pertains to understanding and treating various forms of cancer. We will consider various computational and experimental techniques being used in the field of systems biology, focusing on how systems principles have helped advance biological understanding. We will also discuss the application of the principles of systems biology and network biology to drug development, an emerging discipline called "network medicine." This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive sett

Subjects

systems biology | network medicine | cancer | cancer therapeutics | quantitative high-throughput data acquisition | genomic analysis | signaling network biology | statistical/computational modeling | network biology | drug development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

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Description

This course provides an introduction to the physical chemistry of biological systems. Topics include: connection of macroscopic thermodynamic properties to microscopic molecular properties using statistical mechanics, chemical potentials, equilibrium states, binding cooperativity, behavior of macromolecules in solution and at interfaces, and solvation. Example problems include protein structure, genomic analysis, single molecule biomechanics, and biomaterials.

Subjects

physical chemistry of biological systems | macroscopic thermodynamic properties | microscopic molecular properties | statistical mechanics | chemical potentials | equilibrium states | binding cooperativity | behavior of macromolecules in solution and at interfaces | solvation | protein structure | genomic analysis | single molecule biomechanics | biomaterials | BE.011J | BE.011 | 2.772

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-alllifesciencescourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

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