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A0026P0002

Description

A 7 year old female Jack Russell Terrier with a nail bed infection.

Subjects

svmsvet | dog | nail | infection | a0026 | nailinfection | clawinfection | onchodystrophy | nailbed | nailbedinfection

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A0026P0001

Description

A 7 year old female Jack Russell Terrier with a nail bed infection.

Subjects

svmsvet | dog | nail | infection | a0026 | nailinfection | clawinfection | onchodystrophy | nailbed | nailbedinfection

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0026P0002

Description

A 7 year old female Jack Russell Terrier with a nail bed infection.

Subjects

svmsvet | dog | nail | infection | a0026 | nailinfection | clawinfection | onchodystrophy | nailbed | nailbedinfection

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0026P0001

Description

A 7 year old female Jack Russell Terrier with a nail bed infection.

Subjects

svmsvet | dog | nail | infection | a0026 | nailinfection | clawinfection | onchodystrophy | nailbed | nailbedinfection

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Essentials of Medical Microbiology I - Part 2 of 2

Description

This resource provides an introduction into Medical Microbiology and should be used in conjunction with Part 1 - Part 1 of 1. The unit comprises factors that affect the spread of infection and a detailed description of the human commensal microbiota. A help file is included and should be read first.

Subjects

human commensal microbiota | pathogens | cycle of infection | horizontal spread | vertical spread | exogenous infection | endogenous infection | blood-borne infection | bioukoer | ukoer | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Essentials of Medical Microbiology II - Part 3 of 4

Description

This presentation explains about infections of the heart and circulatory system, and respiratory infections. It forms part 3 of the Essentials of Medical Microbiology II suite of materials. A help file is included which should be read first.

Subjects

bioukoer | ukoer | intracellular pathogens | plague | opportunistic infection | endotoxic shock | endocarditis | tonsilitis | diphtheria | epiglottitis | influenza | middle ear infections | pneumonia | psittacosis | bronchiolitis | whooping cough | medical microbiology | heart and circulatory infection | respiratory infection | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Essentials of Medical Microbiology II - Part 4 of 4

Description

This presentation deals with bone, joint and soft tissue infections. It is the final part of the Essentials of Medical Microbiology II suite of materials. A help file is included and should be read first.

Subjects

osteomyelitis | arthritis | hepatitis | impetigo | cellulitis | typhoid | bioukoer | ukoer | infections of the oral cavity | dental caries | cold sores | skin infections | staphylococcal infection | necrotising fasciitis | gangrene | leprosy | mycobacterial infections | anthrax | typhus | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Essentials of Medical Microbiology II - Part 1 of 4

Description

This presentation describes the infections of the urinary tract and sexually transmitted diseases. Topics covered include the causes, symptoms and diagnosis of UTI’s, and a comprehensive description of sexually tramsmitted diseases.It forms part 1 of the Essential Medical Microbiology II suite of materials.

Subjects

urinary tract infections | cause of infection | symptoms of infection | diagnosis | sexually transmitted diseases | aids | syphillis | gonorrhoea | thrush | herpes simplex | genital warts | crabs and scabies | ukoer | bioukoer | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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7.343 Sophisticated Survival Skills of Simple Microorganisms (MIT) 7.343 Sophisticated Survival Skills of Simple Microorganisms (MIT)

Description

In this course, we will discuss the microbial physiology and genetics of stress responses in aquatic ecosystems, astrobiology, bacterial pathogenesis and other environments. We will learn about classical and novel methods utilized by researchers to uncover bacterial mechanisms induced under both general and environment-specific stresses. Finally, we will compare and contrast models for bacterial stress responses to gain an understanding of distinct mechanisms of survival and of why there are differences among bacterial genera. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly In this course, we will discuss the microbial physiology and genetics of stress responses in aquatic ecosystems, astrobiology, bacterial pathogenesis and other environments. We will learn about classical and novel methods utilized by researchers to uncover bacterial mechanisms induced under both general and environment-specific stresses. Finally, we will compare and contrast models for bacterial stress responses to gain an understanding of distinct mechanisms of survival and of why there are differences among bacterial genera. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly

Subjects

microbial physiology | microbial physiology | genetics | genetics | stress | stress | astrobiology | astrobiology | pathogenesis | pathogenesis | Escherichia coli | Escherichia coli | cyanobacteria | cyanobacteria | bleaching | bleaching | deprivation | deprivation | chlorosis | chlorosis | pollutants | pollutants | methylobacteria | methylobacteria | pathogen | pathogen | reactive oxygen species | reactive oxygen species | infection | infection | superoxides | superoxides | phage | phage | Deinococcus | Deinococcus | Raman spectroscopy | Raman spectroscopy

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.342 Chronic Infection and Inflammation: What are the Consequences on Your Health? (MIT) 7.342 Chronic Infection and Inflammation: What are the Consequences on Your Health? (MIT)

Description

In this course we will explore the new emerging field of pathogen-induced chronic diseases. Work in this field has redefined the causes of some major disorders, such as ulcers. By reading the primary research literature we will learn about the molecular mechanisms through which pathogens cause disease. The diseases that we cover will be introduced with a short patient case study. We will discuss the bacterium Helicobacter pylori and gastric disease, HPV and cervical cancer, hepatitis C virus and liver disease, Epstein-Barr virus and lymphoma, Cytomegalovirus and atherosclerosis, as well as diabetes and multiple sclerosis. We will study technical advances in the fight against microbes and explore future directions for new treatment strategies of chronic infections and inflammation. This cou In this course we will explore the new emerging field of pathogen-induced chronic diseases. Work in this field has redefined the causes of some major disorders, such as ulcers. By reading the primary research literature we will learn about the molecular mechanisms through which pathogens cause disease. The diseases that we cover will be introduced with a short patient case study. We will discuss the bacterium Helicobacter pylori and gastric disease, HPV and cervical cancer, hepatitis C virus and liver disease, Epstein-Barr virus and lymphoma, Cytomegalovirus and atherosclerosis, as well as diabetes and multiple sclerosis. We will study technical advances in the fight against microbes and explore future directions for new treatment strategies of chronic infections and inflammation. This cou

Subjects

Seminar | Seminar | literature review | literature review | cancer | cancer | vaccine | vaccine | antibiotic | antibiotic | chronic | chronic | atherosclerosis | atherosclerosis | diabetes | diabetes | human papilloma virus | human papilloma virus | HPV | HPV | helicobacter pylori | helicobacter pylori | epstein-barr | epstein-barr | treatment strategies | treatment strategies | laboratory techniques | laboratory techniques | lab | lab | herpes | herpes | microbes | microbes | infection | infection | health | health | Epstein-Barr | Epstein-Barr | cervical cancer | cervical cancer | cirrhosis | cirrhosis | multiple sclerosis | multiple sclerosis | hepatitis | hepatitis | hepatocellular carcinoma | hepatocellular carcinoma | gastric | gastric

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Iron Metabolism

Description

Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections. Iron plays essential biochemical roles in oxygen binding, ATP synthesis and DNA metabolism. The level of iron available in different tissues is controlled by the small peptide hormone hepcidin. Dr Hal Drakesmith studies how hepcidin is modulated during infections, since iron availability plays an important role in the course of major infectious diseases such as HIV, malaria and Hepatitis C. Genetic variation plays an important role in individual susceptibility to many common diseases. New insights into genetic variants which modulate gene expression allow us to better understand why people develop these diseases. We can then target treatments much more effectively. Ultimately, we will be able to iden Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

malaria | hiv | Immune System | infection | hepcidin | iron | hepatitis C | ferroportin | malaria | hiv | Immune System | infection | hepcidin | iron | hepatitis C | ferroportin

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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EC.S06 Prototypes to Products (MIT) EC.S06 Prototypes to Products (MIT)

Description

Includes audio/video content: AV special element video. For students and teams who have started a sustainable-development project in D-Lab (EC.701J or EC.720J), Product Engineering Processes (2.009), or elsewhere, this class provides a setting to continue developing projects for field implementation. Topics covered include prototyping techniques, materials selection, design-for-manufacturing, field-testing, and project management. All classwork will directly relate to the students' projects, and the instructor will consult on the projects during weekly lab time. There are no exams. Teams are encouraged to enroll together. Includes audio/video content: AV special element video. For students and teams who have started a sustainable-development project in D-Lab (EC.701J or EC.720J), Product Engineering Processes (2.009), or elsewhere, this class provides a setting to continue developing projects for field implementation. Topics covered include prototyping techniques, materials selection, design-for-manufacturing, field-testing, and project management. All classwork will directly relate to the students' projects, and the instructor will consult on the projects during weekly lab time. There are no exams. Teams are encouraged to enroll together.

Subjects

solar water disinfection | solar water disinfection | SODIS | SODIS | internet kiosk | internet kiosk | developing nation | developing nation | appropriate technology | appropriate technology | sustainable development | sustainable development | international development | international development | prototyping | prototyping | product design | product design | Gantt chart | Gantt chart | Pert chart | Pert chart | SWOT | SWOT | funding | funding | entrepreneurship | entrepreneurship

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT) 7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT)

Description

Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation. Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.

Subjects

immunology | immunology | immune system | immune system | immune evasion | immune evasion | pathogen | pathogen | effector function | effector function | infections | infections | Human cytomegalovirus | Human cytomegalovirus | Human Immunodeficiency Virus | Human Immunodeficiency Virus | CD4 cells | CD4 cells | CD8 cells | CD8 cells | T cells | T cells | surace receptors | surace receptors | cell lysis | cell lysis | host-pathogen interactions | host-pathogen interactions | host surveillance | host surveillance | antibodies | antibodies | MHC class I | MHC class I | blood-borne pathogens | blood-borne pathogens | macrophages | macrophages | phagocytosis | phagocytosis | endocytosis | endocytosis | degradation | degradation | antigen | antigen | apoptosis | apoptosis | cytokines | cytokines | immune response | immune response

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.345 The War on Superbugs: Antibiotic Development and the Emergence of Drug-Resistant Bacteria (MIT) 7.345 The War on Superbugs: Antibiotic Development and the Emergence of Drug-Resistant Bacteria (MIT)

Description

Bacteria and fungi have produced antibiotics, small molecules that can prevent the growth of or kill bacteria by inhibiting essential biological pathways, as a defense mechanism long before humans walked the earth. The discovery of antibiotics and their implementation in the clinic radically changed modern medicine, saving countless lives by treating infections that were once difficult to cure, such as syphilis, strep throat and tuberculosis. During this course, we will cover many aspects of antibiotics including techniques used to discover these inhibitors, their mode of action and use in medicine. For example, we will learn about the techniques used to discover antibiotics, such as penicillin and vancomycin. We will discuss antibiotic-resistant bacteria and the molecular mechanisms under Bacteria and fungi have produced antibiotics, small molecules that can prevent the growth of or kill bacteria by inhibiting essential biological pathways, as a defense mechanism long before humans walked the earth. The discovery of antibiotics and their implementation in the clinic radically changed modern medicine, saving countless lives by treating infections that were once difficult to cure, such as syphilis, strep throat and tuberculosis. During this course, we will cover many aspects of antibiotics including techniques used to discover these inhibitors, their mode of action and use in medicine. For example, we will learn about the techniques used to discover antibiotics, such as penicillin and vancomycin. We will discuss antibiotic-resistant bacteria and the molecular mechanisms under

Subjects

superbugs | superbugs | antibiotics | antibiotics | drug-resistance | drug-resistance | bacteria | bacteria | infection | infection | penicillin | penicillin | drug discovery | drug discovery | vancomycin | vancomycin

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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WGS.151 Gender, Health, and Society (MIT) WGS.151 Gender, Health, and Society (MIT)

Description

This course draws on different disciplines, conceptual frameworks, and methodological approaches to examine gender in relation to health, including public health practice, epidemiologic research, health policy, and clinical application. It discusses a variety of health-related issues that illustrate global, international, domestic, and historical perspectives, while considering other social determinants of health as well, including social class and race. This course draws on different disciplines, conceptual frameworks, and methodological approaches to examine gender in relation to health, including public health practice, epidemiologic research, health policy, and clinical application. It discusses a variety of health-related issues that illustrate global, international, domestic, and historical perspectives, while considering other social determinants of health as well, including social class and race.

Subjects

gender | gender | health | health | society | society | public health | public health | epidemiology | epidemiology | cardiovascular disease | cardiovascular disease | hormone therapy | hormone therapy | contraceptives | contraceptives | sexually transmitted infection | sexually transmitted infection | pregnancy | pregnancy | birth | birth | mental health | mental health | motherhood | motherhood | biology | biology | abortion | abortion | sexual orientation | sexual orientation | gender identity | gender identity | global policy | global policy

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Urinary Tract Infections

Description

A unit containing a series of case studies in which a clinical presentation of an UTI is described. The reader is required to diagnose the infection and the treatment required. A full explanation of the correct answers is provided. This is a Questionmark Perception file. The QTIXML file needs to be opened in QP Authoring Manager, converted to an assessment and exported into your own VLE.

Subjects

urinary tract infections | diagnosis | bacteria | infection | treatment | clinical case | case study | bioukoer | ukoer | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Dental Care in an injection drug user

Description

A scenario-based teaching aid describing best practice when dealing with an IV drug user during dental treatment. The unit describes how to deal with potential infections, and the necessary steps to be taken to reduce the risk of acquiring infection from this patient.

Subjects

microbiology | healthcare | iv | infection | infection control | hand washing | ukoer | bioukoer | dental care | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Hand washing

Description

This topic starts with a description about the importance of handwashing in the prevention of spread of infection in a hospital environment. A step-by-step guide of how to wash your hands properly, comprising of washing, drying and moisturising, is also included. Three microbiological demonstrations comparing before and after handwashing specimens are illustrated on agar plates to reinforce the importance of handwashing.

Subjects

handwashing | disinfection | infection | washing | drying | moisturising | agar plate | microbiology | ukoer | ooer | medev | Medicine and Dentistry | Subjects allied to Medicine | Biological Sciences | Analytical | Diagnostic and Therapeutic Techniques and Equipment | Health Care | Learning | Teaching | Institutions | Students | UK EL10 = SCQF 10 | Honours degree | Graduate diploma | dentistry | A000

License

Attribution-Share Alike 2.0 UK: England & Wales Attribution-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-sa/2.0/uk/ http://creativecommons.org/licenses/by-sa/2.0/uk/

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SP.722 D-Lab: Development, Design and Dissemination (MIT) SP.722 D-Lab: Development, Design and Dissemination (MIT)

Description

D-Lab: Development, Design and Dissemination is a design studio course in which students work on international development projects for underserved communities. The class is focused on a participatory, iterative prototyping design process, with particular attention on the constraints faced when designing for developing communities. Students work in multidisciplinary teams on term-long projects in collaboration with community partners, field practitioners, and experts in relevant fields. Students will learn about their partner communities through the collaborative design process and be exposed to many hands-on fabrication and prototyping skills relevant to development at MIT and manufacturing in their partner community. The course will consist of hands-on labs, guest speakers, and a gu D-Lab: Development, Design and Dissemination is a design studio course in which students work on international development projects for underserved communities. The class is focused on a participatory, iterative prototyping design process, with particular attention on the constraints faced when designing for developing communities. Students work in multidisciplinary teams on term-long projects in collaboration with community partners, field practitioners, and experts in relevant fields. Students will learn about their partner communities through the collaborative design process and be exposed to many hands-on fabrication and prototyping skills relevant to development at MIT and manufacturing in their partner community. The course will consist of hands-on labs, guest speakers, and a gu

Subjects

development project | development project | appropriate technology | appropriate technology | sustainable development | sustainable development | intermediate technology | intermediate technology | stakeholder analysis | stakeholder analysis | India | India | Brazil | Brazil | Honduras | Honduras | Zambia | Zambia | Lesotho | Lesotho | Nicaragua | Nicaragua | developing country | developing country | international development | international development | third world | third world | energy | energy | charcoal | charcoal | wheelchair | wheelchair | poverty | poverty | water | water | water quality | water quality | safe water | safe water | water treatment | water treatment | health | health | sanitation | sanitation | AIDS | AIDS | solar water disinfection | solar water disinfection

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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20.450 Molecular and Cellular Pathophysiology (BE.450) (MIT) 20.450 Molecular and Cellular Pathophysiology (BE.450) (MIT)

Description

This course focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and cancer. The systems approach to pathophysiology includes lectures, critical evaluation of recent scientific papers, and student projects and presentations. This term, we focus on hepatocellular carcinoma (HCC), chronic-active hepatitis, and hepatitis virus infections. In addition to lectures, students work in teams to critically evaluate and present primary scientific papers. This course focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and cancer. The systems approach to pathophysiology includes lectures, critical evaluation of recent scientific papers, and student projects and presentations. This term, we focus on hepatocellular carcinoma (HCC), chronic-active hepatitis, and hepatitis virus infections. In addition to lectures, students work in teams to critically evaluate and present primary scientific papers.

Subjects

tissue | tissue | organ; injury | organ; injury | infection | infection | inflammation | inflammation | immunity | immunity | cancer | cancer | pathophysiology | pathophysiology | hepatocellular | hepatocellular | carcinoma | carcinoma | HCC | HCC | chronic-active | chronic-active | hepatitis | hepatitis | virus | virus | Robbins | Robbins | Cotran | Cotran | Pathologic | Pathologic | Disease | Disease | organ | organ | injury | injury

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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BE.450 Molecular and Cellular Pathophysiology (MIT) BE.450 Molecular and Cellular Pathophysiology (MIT)

Description

This course focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and cancer. The systems approach to pathophysiology includes lectures, critical evaluation of recent scientific papers, and student projects and presentations.This term, we focus on hepatocellular carcinoma (HCC), chronic-active hepatitis, and hepatitis virus infections. In addition to lectures, students work in teams to critically evaluate and present primary scientific papers. This course focuses on the fundamentals of tissue and organ response to injury from a molecular and cellular perspective. There is a special emphasis on disease states that bridge infection, inflammation, immunity, and cancer. The systems approach to pathophysiology includes lectures, critical evaluation of recent scientific papers, and student projects and presentations.This term, we focus on hepatocellular carcinoma (HCC), chronic-active hepatitis, and hepatitis virus infections. In addition to lectures, students work in teams to critically evaluate and present primary scientific papers.

Subjects

tissue | tissue | organ; injury | organ; injury | infection | infection | inflammation | inflammation | immunity | immunity | cancer | cancer | pathophysiology | pathophysiology | hepatocellular | hepatocellular | carcinoma | carcinoma | HCC | HCC | chronic-active | chronic-active | hepatitis | hepatitis | virus | virus | Robbins | Robbins | Cotran | Cotran | Pathologic | Pathologic | Disease | Disease | organ | organ | injury | injury

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Childhood Nutrition and Immunity

Description

Dr Jay Berkley tells us about his work on childhood nutrition and immunity in East Africa. Dr Jay Berkley works in the KEMRI/Wellcome Trust Collaborative Research Programme in Kilifi, Kenya. His research interests include tackling infection and inflammation to prevent mortality in malnourished children. He is also an expert advisor on severe acute malnutrition to the Ministries of Health, and the World Health Organisation. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

clinical trials | perinatal | infection | Epidemiology | inflammation | malnutrition | clinical trials | perinatal | infection | Epidemiology | inflammation | malnutrition

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Microbiology research in SE Asia

Description

Dr Direk Limmathurotsakul's research focuses on the epidemiology of melioidosis, a bacterial infection caused by Burkholderia pseudomallei. Melioidosis is endemic in at least 45 countries, but greatly under-reported. Up to 50% of cases seen in hospital die. Our researchers at MORU have produced a rapid diagnostic test that aims to improve both diagnosis and public awareness. Better coordination between researchers and policy makers is needed to face upcoming emerging infectious diseases. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

melioidosis | Epidemiology | baterial infection | diagnosis | public awareness | melioidosis | Epidemiology | baterial infection | diagnosis | public awareness

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Iron Metabolism

Description

Dr Hal Drakesmith tells us how his work on iron availability can help us fight infections. Iron plays essential biochemical roles in oxygen binding, ATP synthesis and DNA metabolism. The level of iron available in different tissues is controlled by the small peptide hormone hepcidin. Dr Hal Drakesmith studies how hepcidin is modulated during infections, since iron availability plays an important role in the course of major infectious diseases such as HIV, malaria and Hepatitis C. Genetic variation plays an important role in individual susceptibility to many common diseases. New insights into genetic variants which modulate gene expression allow us to better understand why people develop these diseases. We can then target treatments much more effectively. Ultimately, we will be able to iden Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

malaria | hiv | Immune System | infection | hepcidin | iron | hepatitis C | ferroportin | malaria | hiv | Immune System | infection | hepcidin | iron | hepatitis C | ferroportin

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Tracking infections

Description

Professor Derrick Crook from our Experimental Medicine division tells us about his research on tracking infections Professor Derrick Crook's research consortium focusses on translating new molecular technologies and advances in informatics into the investigation of microbial transmission, diagnosis of infectious disease and identifying outbreaks of communicable disease. This research aims to translate deep sequencing of pathogens on an epidemiological scale for tracking infections, and is focussed on four different major pathogens: Staphylococcus aureus (including MRSA), Clostridium difficile, Norovirus and Mycobacterium tuberculosis. Understanding how an infection spreads is vitally important for prevention. Whole genome sequencing of microorganisms allows us to construct family trees of Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

translational medicine | infections | tuberculosis | genetics | viruses | translational medicine | infections | tuberculosis | genetics | viruses

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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