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B0095P0007

Description

A cat with immune mediated haemolytic anaemia showing signs of jaundice

Subjects

svmsvet | cat | cats | feline | felines | b0095 | imha | immunemediatedhaemolyticanaemia | jaundice | ragdoll | ragdollcat | icterus | jaundicecat | felineimha | felineimmunemediateddisease | haemolyticanaemia | felinehaemolyticanaemia | felineicterus | haemolytic | anaemia | mucousmembranes | ictericmucousmembranes | yellowmucousmembranes | jaundicemucousmembranes

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B0095P0007

Description

A cat with immune mediated haemolytic anaemia showing signs of jaundice

Subjects

svmsvet | cat | cats | feline | felines | b0095 | imha | immunemediatedhaemolyticanaemia | jaundice | ragdoll | ragdollcat | icterus | jaundicecat | felineimha | felineimmunemediateddisease | haemolyticanaemia | felinehaemolyticanaemia | felineicterus | haemolytic | anaemia | mucousmembranes | ictericmucousmembranes | yellowmucousmembranes | jaundicemucousmembranes

License

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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | BE.370 | BE.370 | BE.470 | BE.470 | HST.541 | HST.541

License

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8.592 Statistical Physics in Biology (MIT) 8.592 Statistical Physics in Biology (MIT)

Description

Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; Considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.Technical RequirementsAny number of biological sequence comparison software tools can be used to import the .fna files found on this course site. Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; Considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.Technical RequirementsAny number of biological sequence comparison software tools can be used to import the .fna files found on this course site.

Subjects

Bioinformatics | Bioinformatics | DNA | DNA | gene finding | gene finding | sequence comparison | sequence comparison | phylogenetic trees | phylogenetic trees | biopolymers | biopolymers | DNA double helix | DNA double helix | secondary structure of RNA | secondary structure of RNA | protein folding | protein folding | protein motors | membranes | protein motors | membranes | cellular networks | cellular networks | neural networks | neural networks | evolution | evolution | statistical physics | statistical physics | molecular biology | molecular biology | deoxyribonucleic acid | deoxyribonucleic acid | genes | genes | genetics | genetics | gene sequencing | gene sequencing | phylogenetics | phylogenetics | double helix | double helix | RNA | RNA | ribonucleic acid | ribonucleic acid | force | force | motion | motion | packaging | packaging | protein motors | protein motors | membranes | membranes | biochemistry | biochemistry | genome | genome | optimization | optimization | partitioning | partitioning | pattern recognition | pattern recognition | collective behavior | collective behavior

License

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20.310J Molecular, Cellular, and Tissue Biomechanics (MIT) 20.310J Molecular, Cellular, and Tissue Biomechanics (MIT)

Description

This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level. This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level.

Subjects

biomechanics | biomechanics | molecular mechanics | molecular mechanics | cell mechanics | cell mechanics | Brownian motion | Brownian motion | Reynolds numbers | Reynolds numbers | mechanochemistry | mechanochemistry | Kramers' model | Kramers' model | Bell model | Bell model | viscoelasticity | viscoelasticity | poroelasticity | poroelasticity | optical tweezers | optical tweezers | extracellular matrix | extracellular matrix | collagen | collagen | proteoglycan | proteoglycan | cell membrane | cell membrane | cell motility | cell motility | mechanotransduction | mechanotransduction | cancer | cancer | biological systems | biological systems | molecular biology | molecular biology | cell biology | cell biology | cytoskeleton | cytoskeleton | cell | cell | biophysics | biophysics | cell migration | cell migration | biomembrane | biomembrane | tissue mechanics | tissue mechanics | rheology | rheology | polymer | polymer | length scale | length scale | muscle mechanics | muscle mechanics | experimental methods | experimental methods

License

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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | equilibrium potential | equilibrium potential | resting potential | resting potential | action potential | action potential | voltage-gated ion channels | voltage-gated ion channels | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | 20.370 | 20.370 | 20.470 | 20.470 | HST.541 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.32 Separation Processes (MIT) 10.32 Separation Processes (MIT)

Description

This course covers the general principles of separation by equilibrium and rate processes. Topics include staged cascades and applications to distillation, absorption, adsorption, and membrane processes. Phase equilibria and the role of diffusion are also covered. This course covers the general principles of separation by equilibrium and rate processes. Topics include staged cascades and applications to distillation, absorption, adsorption, and membrane processes. Phase equilibria and the role of diffusion are also covered.

Subjects

separation process | separation process | chemical mixtures | chemical mixtures | biological mixtures | biological mixtures | distillation | distillation | membrane processes | membrane processes | chromatography | chromatography | adsorption | adsorption | precipitation | precipitation | crystallization | crystallization | filtration | filtration | membrane filtration | membrane filtration | fixed bed adsorption | fixed bed adsorption | reverse osmosis | reverse osmosis | McCabe-Thiele | McCabe-Thiele | stripping | stripping | equilibrium | equilibrium | rate processes | rate processes | staged cascades | staged cascades | absorption | absorption | phase equilibria | phase equilibria | diffusion | diffusion

License

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A0014P0013

Description

Mucus membranes of a cat during anaesthesia induced with medetomidine

Subjects

svmsvet | cat | cats | feline | felines | mucousmembranes | mucousmembranecolour | catmucousmembranes | anaesthesia | medetomidine

License

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A0014P0013

Description

Mucus membranes of a cat during anaesthesia induced with medetomidine

Subjects

svmsvet | cat | cats | feline | felines | mucousmembranes | mucousmembranecolour | catmucousmembranes | anaesthesia | medetomidine

License

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B0049P0037

Description

Mucous membranes of an anesthetised cat

Subjects

svmsvet | cat | cats | feline | felines | mucousmembranes | mucousmembranecolour | mm | anaesthetisedcat

License

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7.06 Cell Biology (MIT) 7.06 Cell Biology (MIT)

Description

This course deals with the biology of cells of higher organisms: The structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis. This course deals with the biology of cells of higher organisms: The structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis.

Subjects

Biology | Biology | cells | cells | organisms | organisms | biosynthesis | biosynthesis | cellular membranes | cellular membranes | organelles | organelles | cell growth | cell growth | oncogenic transformation | oncogenic transformation | transport | transport | receptors | receptors | cell signaling | cell signaling | cytoskeleton | cytoskeleton | extracellular matrix | extracellular matrix | matrix | matrix | cell movements | cell movements | chromatin | chromatin | RNA | RNA | RNA synthesis | RNA synthesis

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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8.592J Statistical Physics in Biology (MIT) 8.592J Statistical Physics in Biology (MIT)

Description

Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution. Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.

Subjects

Bioinformatics | Bioinformatics | DNA | DNA | gene finding | gene finding | sequence comparison | sequence comparison | phylogenetic trees | phylogenetic trees | biopolymers | biopolymers | DNA double helix | DNA double helix | secondary structure of RNA | secondary structure of RNA | protein folding | protein folding | protein motors | protein motors | membranes | membranes | cellular networks | cellular networks | neural networks | neural networks | evolution | evolution

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.340 Ubiquitination: The Proteasome and Human Disease (MIT) 7.340 Ubiquitination: The Proteasome and Human Disease (MIT)

Description

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. This seminar provides a deeper understanding of the post-translational mechanisms evolved by eukaryotic cells to target proteins for degradation. Students learn how proteins are recognized and degraded by specific machinery (the proteasome) through their previous tagging with another small protein, ubiquitin. Additional topics include principles of ubiquitin-proteasome function, its control of the most important cellular pathways, and the implication of this system in different human diseases. Finally, spe This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. This seminar provides a deeper understanding of the post-translational mechanisms evolved by eukaryotic cells to target proteins for degradation. Students learn how proteins are recognized and degraded by specific machinery (the proteasome) through their previous tagging with another small protein, ubiquitin. Additional topics include principles of ubiquitin-proteasome function, its control of the most important cellular pathways, and the implication of this system in different human diseases. Finally, spe

Subjects

ubiquitination | ubiquitination | ubiquitin | ubiquitin | proteasome | proteasome | post-translational mechanisms | post-translational mechanisms | ubiquitin-conjugation system | ubiquitin-conjugation system | neurodegenerative diseases | neurodegenerative diseases | immune response | immune response | cell cycle regulation | cell cycle regulation | apoptosis | apoptosis | signal transduction pathways | signal transduction pathways | tumorigenesis | tumorigenesis | protein degradation | protein degradation | Endoplasmic Reticulum Associated Degradation Pathway | Endoplasmic Reticulum Associated Degradation Pathway | ligases | ligases | translocated proteins | translocated proteins | misfolded proteins | misfolded proteins | trafficking membranes | trafficking membranes | cell cycle control | cell cycle control | programmed cell death | programmed cell death | Huntington's Disease | Huntington's Disease | Von Hippel-Lindau Disease | Von Hippel-Lindau Disease

License

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Chemical and Environmental Behaviour of Materials: Fuel Cells

Description

This set of animations demonstrates the principles of a solid oxide fuel cell and a proton exchange membrane cell. From TLP: Fuel Cells

Subjects

fuel cells | SOFC | PEMFC | Solid oxide fuel cell | Proton exchange membrane fuel cell | polymer electrolyte membrane fuel cell | DoITPoMS | University of Cambridge | animation | corematerials | ukoer

License

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8.592J Statistical Physics in Biology (MIT) 8.592J Statistical Physics in Biology (MIT)

Description

Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution. Statistical Physics in Biology is a survey of problems at the interface of statistical physics and modern biology. Topics include: bioinformatic methods for extracting information content of DNA; gene finding, sequence comparison, and phylogenetic trees; physical interactions responsible for structure of biopolymers; DNA double helix, secondary structure of RNA, and elements of protein folding; considerations of force, motion, and packaging; protein motors, membranes. We also look at collective behavior of biological elements, cellular networks, neural networks, and evolution.

Subjects

8.592 | 8.592 | HST.452 | HST.452 | Statistical physics | Statistical physics | Bioinformatics | Bioinformatics | DNA | DNA | gene finding | gene finding | sequence comparison | sequence comparison | phylogenetic trees | phylogenetic trees | biopolymers | biopolymers | DNA double helix | DNA double helix | secondary structure of RNA | secondary structure of RNA | protein folding | protein folding | protein motors | protein motors | membranes | membranes | cellular networks | cellular networks | neural networks | neural networks | evolution | evolution

License

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B0095P0016

Description

A cat with immune mediated haemolytic anaemia showing signs of jaundice

Subjects

svmsvet | cat | cats | feline | felines | b0095 | imha | immunemediatedhaemolyticanaemia | jaundice | ragdoll | ragdollcat | icterus | jaundicecat | felineimha | felineimmunemediateddisease | haemolyticanaemia | felinehaemolyticanaemia | felineicterus | haemolytic | anaemia | mucous | membranesicteric | membranes

License

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9.01 Introduction to Neuroscience (MIT) 9.01 Introduction to Neuroscience (MIT)

Description

This course is an introduction to the mammalian nervous system, with emphasis on the structure and function of the human brain. Topics include the function of nerve cells, sensory systems, control of movement, learning and memory, and diseases of the brain. This course is an introduction to the mammalian nervous system, with emphasis on the structure and function of the human brain. Topics include the function of nerve cells, sensory systems, control of movement, learning and memory, and diseases of the brain.

Subjects

neuroscience | neuroscience | vision | vision | hearing | hearing | neuroanatomy | neuroanatomy | color vision | color vision | blind spot | blind spot | retinal phototransduction | retinal phototransduction | cortical maps | cortical maps | primary visual cortex | primary visual cortex | complex cells | complex cells | extrastriate cortex | extrastriate cortex | ear | ear | cochlea | cochlea | basilar membrane | basilar membrane | auditory transduction | auditory transduction | hair cells | hair cells | phase-locking | phase-locking | sound localization | sound localization | auditory cortex | auditory cortex | somatosensory system | somatosensory system | motor system | motor system | synaptic transmission | synaptic transmission | action potential | action potential | sympathetic neurons | sympathetic neurons | parasympathetic neurons | parasympathetic neurons | cellual neurophysiology | cellual neurophysiology | learning | learning | memory | memory

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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9.013J Cell and Molecular Neurobiology (MIT) 9.013J Cell and Molecular Neurobiology (MIT)

Description

This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience. This course explores the major areas of cellular and molecular neurobiology, including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell-type determination, axon guidance, neuronal cell biology, neurotrophin signaling and cell survival, synapse formation and neural plasticity. Material includes lectures and exams, and involves presentation and discussion of primary literature. It focuses on major concepts and recent advances in experimental neuroscience.

Subjects

cellular | cellular | molecular neurobiology | molecular neurobiology | cells | cells | membranes | membranes | ion channels | ion channels | receptors | receptors | synaptic transmission | synaptic transmission | axon guidance | axon guidance | targeting | targeting | neuronal cell biology | neuronal cell biology | synapse formation | synapse formation | plasticity | plasticity

License

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B0095P0016

Description

A cat with immune mediated haemolytic anaemia showing signs of jaundice

Subjects

svmsvet | cat | cats | feline | felines | b0095 | imha | immunemediatedhaemolyticanaemia | jaundice | ragdoll | ragdollcat | icterus | jaundicecat | felineimha | felineimmunemediateddisease | haemolyticanaemia | felinehaemolyticanaemia | felineicterus | haemolytic | anaemia | mucous | membranesicteric | membranes

License

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BE.430J Fields, Forces, and Flows in Biological Systems (MIT) BE.430J Fields, Forces, and Flows in Biological Systems (MIT)

Description

This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples. This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples.

Subjects

biomaterials | biomaterials | conduction | conduction | diffusion | diffusion | convection in electrolytes | convection in electrolytes | fields in heterogeneous media | fields in heterogeneous media | electrical double layers | electrical double layers | Maxwell stress tensor | Maxwell stress tensor | fluid and solid continua | fluid and solid continua | biological tissues | biological tissues | membrane transport | membrane transport | electrode | electrode | transduction | transduction | electrophoretic flow | electrophoretic flow | electroosmotic flow | electroosmotic flow | diffusion reaction | diffusion reaction | ECG | ECG | orthopaedic | cardiovascular | orthopaedic | cardiovascular | 2.795J | 2.795J | 2.795 | 2.795 | 6.561J | 6.561J | 6.561 | 6.561 | 10.539J | 10.539J | 10.539 | 10.539 | HST.544J | HST.544J | HST.544 | HST.544

License

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20.330J Fields, Forces and Flows in Biological Systems (MIT) 20.330J Fields, Forces and Flows in Biological Systems (MIT)

Description

This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics. This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics.

Subjects

hydrodynamic flow | hydrodynamic flow | electroosmosis | electroosmosis | diffusion | diffusion | electrophoresis | electrophoresis | reaction | reaction | membrane | membrane | cell | cell | biomolecule | biomolecule | microfluidics | microfluidics | ion transport | ion transport | electrokinetics | electrokinetics | Debye layer | Debye layer | Zeta potential | Zeta potential | inviscid flow | inviscid flow | viscous flow | viscous flow | tissue | tissue | organ | organ | biology | biology | molecular biology | molecular biology | Maxwell's equations | Maxwell's equations | electro-quasistatics | electro-quasistatics | Van der Waals | Van der Waals | bioMEMS | bioMEMS

License

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20.410J Molecular, Cellular and Tissue Biomechanics (BE.410J) (MIT) 20.410J Molecular, Cellular and Tissue Biomechanics (BE.410J) (MIT)

Description

This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales. Topics include: structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. Experimental methods for probing structures at the tissue, cellular, and molecular levels will also be investigated. This course was originally co-developed by Professors Alan Grodzinsky, Roger Kamm, and L. Mahadevan. This course develops and applies scaling laws and the methods of continuum mechanics to biomechanical phenomena over a range of length scales. Topics include: structure of tissues and the molecular basis for macroscopic properties; chemical and electrical effects on mechanical behavior; cell mechanics, motility and adhesion; biomembranes; biomolecular mechanics and molecular motors. Experimental methods for probing structures at the tissue, cellular, and molecular levels will also be investigated. This course was originally co-developed by Professors Alan Grodzinsky, Roger Kamm, and L. Mahadevan.

Subjects

Scaling laws | Scaling laws | continuum mechanics | continuum mechanics | biomechanical phenomena | biomechanical phenomena | length scales | length scales | tissue structure | tissue structure | molecular basis for macroscopic properties | molecular basis for macroscopic properties | chemical and electrical effects on mechanical behavior | chemical and electrical effects on mechanical behavior | cell mechanics | motility and adhesion | cell mechanics | motility and adhesion | biomembranes | biomembranes | biomolecular mechanics and molecular motors | biomolecular mechanics and molecular motors | Experimental methods | Experimental methods | BE.410J | BE.410J | BE.410 | BE.410 | 2.798 | 2.798 | 6.524 | 6.524

License

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20.310J Molecular, Cellular, and Tissue Biomechanics (MIT)

Description

This course develops and applies scaling laws and the methods of continuum and statistical mechanics to biomechanical phenomena over a range of length scales, from molecular to cellular to tissue or organ level.

Subjects

biomechanics | molecular mechanics | cell mechanics | Brownian motion | Reynolds numbers | mechanochemistry | Kramers' model | Bell model | viscoelasticity | poroelasticity | optical tweezers | extracellular matrix | collagen | proteoglycan | cell membrane | cell motility | mechanotransduction | cancer | biological systems | molecular biology | cell biology | cytoskeleton | cell | biophysics | cell migration | biomembrane | tissue mechanics | rheology | polymer | length scale | muscle mechanics | experimental methods

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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20.430J Fields, Forces, and Flows in Biological Systems (BE.430J) (MIT) 20.430J Fields, Forces, and Flows in Biological Systems (BE.430J) (MIT)

Description

This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples. This course covers the following topics: conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and solid continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG. The course also examines electromechanical and physicochemical interactions in biomaterials and cells; orthopaedic, cardiovascular, and other clinical examples.

Subjects

biomaterials | biomaterials | conduction | conduction | diffusion | diffusion | convection in electrolytes | convection in electrolytes | fields in heterogeneous media | fields in heterogeneous media | electrical double layers | electrical double layers | Maxwell stress tensor | Maxwell stress tensor | fluid and solid continua | fluid and solid continua | biological tissues | biological tissues | membrane transport | membrane transport | electrode | electrode | transduction | transduction | electrophoretic flow | electrophoretic flow | electroosmotic flow | electroosmotic flow | diffusion reaction | diffusion reaction | ECG | ECG | orthopaedic | cardiovascular | orthopaedic | cardiovascular | 20.430 | 20.430 | 2.795 | 2.795 | 6.561 | 6.561 | 10.539 | 10.539 | HST.544 | HST.544

License

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Membrane proteins and drug development

Description

Dr Liz Carpenter talks about her research on membrane proteins and drug development. Membrane proteins are the gateways to our cells - with nutrients, waste products, and even DNA and proteins entering and leaving cells via these tightly controlled proteins. Drugs often target membrane proteins; therefore, understanding their molecular structure helps us design better drugs. Dr Liz Carpenter uses X-ray crystallography to solve membrane protein structures. This information is then used to improve treatments for heart disease and neurological diseases. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

membrane proteins | protein structure | high-throughput | drug discovery | ion channel | x-ray crystallography | membrane proteins | protein structure | high-throughput | drug discovery | ion channel | x-ray crystallography

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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