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7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT) 7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT)

Description

Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a

Subjects

genome sequencing | genome sequencing | genome analysis | genome analysis | disease susceptibility | disease susceptibility | drug metabolism | drug metabolism | human ancestry | human ancestry | mitochondrial DNA | mitochondrial DNA | tyrosine kinase inhibitors | tyrosine kinase inhibitors | BCR-ABL gene fusion | BCR-ABL gene fusion | PCSK9 inhibitors | PCSK9 inhibitors | hypercholesterolemia | hypercholesterolemia | genetic testing | genetic testing | next generation sequencing | next generation sequencing | Single-nucleotide polymorphisms (SNPs) | Single-nucleotide polymorphisms (SNPs) | copy number variations (CNVs) | copy number variations (CNVs) | genome-wide association studies (GWAS) | genome-wide association studies (GWAS) | Chronic myelogenous leukemia (CML) | Chronic myelogenous leukemia (CML) | mosaics | mosaics | chimeras | chimeras | bioinformatics | bioinformatics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Supposed sepulchre near Mitla Supposed sepulchre near Mitla

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Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | tombs | tombs | mitla | mitla

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Flash Light view in new Subterranean Flash Light view in new Subterranean

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Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | subterranean | subterranean | palaces | palaces | mitla | mitla

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View of Mitla Church built in the Ruins View of Mitla Church built in the Ruins

Description

Subjects

trees | trees | plants | plants | mountains | mountains | buildings | buildings | de | de | landscapes | landscapes | ruins | ruins | san | san | pablo | pablo | churches | churches | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | palaces | palaces | mitla | mitla

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Part of Mitla ruins surround the Church Part of Mitla ruins surround the Church

Description

Subjects

trees | trees | plants | plants | mountains | mountains | buildings | buildings | de | de | landscapes | landscapes | ruins | ruins | san | san | mila | mila | pablo | pablo | churches | churches | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | palaces | palaces

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View in the old subterranean, Mitla View in the old subterranean, Mitla

Description

Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | subterranean | subterranean | palaces | palaces | mitla | mitla

License

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North Wall of Palace of Mosaics Mitla North Wall of Palace of Mosaics Mitla

Description

Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | palaces | palaces | mitla | mitla

License

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East Wall of Palace of Mosaics Mitla East Wall of Palace of Mosaics Mitla

Description

Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | palaces | palaces | mitla | mitla | walla | walla

License

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Eastroom. Palace of Mosaics Eastroom. Palace of Mosaics

Description

Subjects

buildings | buildings | de | de | ruins | ruins | san | san | rooms | rooms | pablo | pablo | mosaics | mosaics | oaxaca | oaxaca | walls | walls | palaces | palaces | mitla | mitla | villd | villd

License

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Patio of Mosaics Mitla Ruins Patio of Mosaics Mitla Ruins

Description

Subjects

buildings | buildings | de | de | ruins | ruins | san | san | pablo | pablo | mosaics | mosaics | villa | villa | oaxaca | oaxaca | walls | walls | palaces | palaces | mitla | mitla | patios | patios

License

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California State Building, 1915 Panama-California Exposition

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00137 Title: California State Building, 1915 Panama-California Exposition Photographer: Harold A. Taylor (American, 1878-1960) Architect: Bertram Grosvenor Goodhue (American, 1869-1942) Building Date: ca. 1915 Location: North and Central America: United States; California, San Diego Materials: gelatin silver print Image: 8 x 6.125 in.; 20.32 x 15.5575 cm Provenance: Transfer from the College of Architecture, Art and Planning Persistent URI: hdl.handle.net/1813.001/5s95 There are no known U.S. copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | architecture | windows | reliefsculptures | domes | mosaics | exhibitionbuildings | inscriptions | festoons | panamacaliforniaexpositionsandiegocalifornia | escutcheonscoatsofarms | culidentifier:value=155309000137 | culidentifier:lunafield=accessionnumber

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California State Building, 1915 Panama-California Exposition

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00140 Title: California State Building, 1915 Panama-California Exposition Photographer: Harold A. Taylor (American, 1878-1960) Architect: Bertram Grosvenor Goodhue (American, 1869-1942) Building Date: ca. 1915 Location: North and Central America: United States; California, San Diego Materials: gelatin silver print Image: 7.9134 x 6 in.; 20.1 x 15.24 cm Provenance: Transfer from the College of Architecture, Art and Planning Persistent URI: hdl.handle.net/1813.001/5s98 There are no known U.S. copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | towers | architecture | exhibitionbuildings | domes | mosaics | inscriptions | reliefsculptures | panamacaliforniaexpositionsandiegocalifornia | culidentifier:value=155309000140 | culidentifier:lunafield=accessionnumber

License

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California State Building, 1915 Panama-California Exposition

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00141 Title: California State Building, 1915 Panama-California Exposition Photographer: Harold A. Taylor (American, 1878-1960) Architect: Bertram Grosvenor Goodhue (American, 1869-1942) Building Date: ca. 1915 Location: North and Central America: United States; California, San Diego Materials: gelatin silver print Image: 6.125 x 8 in.; 15.5575 x 20.32 cm Provenance: Transfer from the College of Architecture, Art and Planning Persistent URI: hdl.handle.net/1813.001/5s99 There are no known U.S. copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | architecture | towers | palmtrees | mosaics | panamacaliforniaexpositionsandiegocalifornia | exhibitionbuildings | culidentifier:value=155309000141 | culidentifier:lunafield=accessionnumber

License

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Ravenna, Interior, Temple of San Vitale

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00273 Title: Ravenna, Interior, Temple of San Vitale Photographer: Fratelli Alinari (Italian, 1852-present) Building Date: 526-547 Photograph date: ca. 1865-ca. 1895 Location: Europe: Italy; Ravenna Materials: albumen print Image: 22.6378 x 16.7323 in.; 57.5 x 42.5 cm Style: Byzantine Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sg6 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | churchofsanvitaleravennaitaly | churches | religiousinteriors | mosaics | newtestament | frescoes | tiledfloors | arches | galleries | altars | culidentifier:value=155309000273 | culidentifier:lunafield=accessionnumber

License

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Ravenna, Basilica di San Apollinare Nuovo

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00269 Title: Ravenna, Basilica di San Apollinare Nuovo Photographer: Fratelli Alinari (Italian, 1852-present) Building Date: 6th century Photograph date: ca. 1865-ca. 1895 Location: Europe: Italy; Ravenna Materials: albumen print Image: 17 1/4 x 23.4252 in.; 43.815 x 59.5 cm Style: Byzantine Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sg2 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | santapollinarenuovoravennaitaly | basilicas | religiousinteriors | mosaics | naves | cofferedarches | domes | altars | clerestories | columns | stuccodecorations | arcades | culidentifier:value=155309000269 | culidentifier:lunafield=accessionnumber

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Venice. Southern Fašade of St. Mark's Cathedral and the Doge's Palace

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00108 Title: Venice. Southern Fašade of St. Mark's Cathedral and the Doge's Palace Photographer: Carlo Naya (Italian, 1816-1882) Building Date: 1071 Photograph date: 1876 Location: Europe: Italy; Venice Materials: albumen print Image: 10 5/8 x 13 7/8 in.; 26.9875 x 35.2425 cm Style: Byzantine Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sds There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | architecture | basilicaofsanmarcoveniceitaly | saintmarksbasilicaveniceitaly | basilicas | religiousbuildings | dogespalaceveniceitaly | palaces | piazzasanmarcoveniceitaly | oniondomes | pointedarches | horses | animals | sculpture | quatrefoils | piazzas | trefoilarches | galleries | mosaics | saints | cupolas | palazzoducaleveniceitaly | culidentifier:value=155309000108 | culidentifier:lunafield=accessionnumber

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Rome. Basilica of Saint Paul-Outside-the-Walls (Interior)

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01480 Title: Rome. Basilica of Saint Paul-Outside-the-Walls (Interior) Building Date: ca. 385 Photograph date: ca. 1865-ca. 1895 Location: Europe: Italy; Rome Materials: albumen print Image: 11.0236 x 16.1417 in.; 28 x 41 cm Style: Early Christian Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5tpt There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | basilicaofsaintpaulsoutsidethewallsromeitaly | sanpaolofuorilemuraromeitaly | basilicas | religiousinteriors | baldachins | thrones | canopies | mosaics | arcades | clerestories | corinthiancolumns | sculpture | portraits | jesuschrist | newtestament | culidentifier:value=155309001480 | culidentifier:lunafield=accessionnumber

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Monreale Cathedral (Interior)

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01650 Title: Monreale Cathedral (Interior) Photographer: Giuseppe Incorpora (Italian, active ca. 1860-ca. 1879) Building Date: 1172-1176 Photograph date: ca. 1865-ca. 1885 Location: Europe: Italy; Monreale Materials: albumen print Image: 8.0709 x 10.1181 in.; 20.5 x 25.7 cm Style: Romanesque Provenance: Transfer from the College of Architecture, Art and Planning Persistent URI: hdl.handle.net/1813.001/5tvn There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | cathedralmonrealesicilyitaly | religiousinteriors | mosaics | apses | frescoes | capitals | aisles | clerestories | altars | culidentifier:value=155309001650 | culidentifier:lunafield=accessionnumber

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Cambridge. St. John's College, Chapel

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.01094 Title: Cambridge. St. John's College, Chapel Architect: Sir George Gilbert Scott (English, 1811-1878) Building Date: ca. 1850-ca. 1878 Photograph date: ca. 1865-ca. 1885 Location: Europe: United Kingdom; Cambridge Materials: albumen print Image: 10 3/8 x 8 3/4 in.; 26.3525 x 22.225 cm Style: Gothic Revival Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5t7b There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | saintjohnscollegecambridgeengland | chapels | religiousinteriors | universitycampuses | stainedglass | lancetwindows | ribbedvaults | corbels | misericordschoirstallcomponents | books | musicstands | lecterns | eagles | birds | animals | mosaics | universities | culidentifier:value=155309001094 | culidentifier:lunafield=accessionnumber

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Oxford. Exeter College Chapel (Looking East)

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00838 Title: Oxford. Exeter College Chapel (Looking East) Architect: Sir George Gilbert Scott (English, 1811-1878) Building Date: 1856 Photograph date: ca. 1865-ca. 1885 Location: Europe: United Kingdom; Oxford Materials: albumen print Image: 8 1/8 x 5 3/8 in.; 20.6375 x 13.6525 cm Style: Victorian Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sxb There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | oxforduniversityoxfordengland | universitycampuses | religiousinteriors | chapels | stainedglass | ribbedvaults | choirs | pews | corbels | altars | eagles | birds | animals | mosaics | wroughtiron | universities | culidentifier:value=155309000838 | culidentifier:lunafield=accessionnumber

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Oxford. Exeter College Chapel (East end)

Description

Collection: A. D. White Architectural Photographs, Cornell University Library Accession Number: 15/5/3090.00834 Title: Oxford. Exeter College Chapel (East end) Architect: Sir George Gilbert Scott (English, 1811-1878) Building Date: 1856 Photograph date: ca. 1865-ca. 1885 Location: Europe: United Kingdom; Oxford Materials: albumen print Image: 11 x 8 1/2 in.; 27.94 x 21.59 cm Style: Victorian Provenance: Gift of Andrew Dickson White Persistent URI: hdl.handle.net/1813.001/5sx6 There are no known copyright restrictions on this image. The digital file is owned by the Cornell University Library which is making it freely available with the request that, when possible, the Library be credited as its source. We had some help with the geocoding from Web Services by Yahoo!

Subjects

cornelluniversitylibrary | oxforduniversityoxfordengland | universitycampuses | chapels | religiousinteriors | choirs | pews | eagles | birds | altars | chandeliers | wroughtiron | fontsreligiousbuildingfixtures | stainedglass | ribbedvaults | mosaics | benches | universities | exetercollegeoxfordengland | culidentifier:value=155309000834 | culidentifier:lunafield=accessionnumber

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7.342 Personal Genomics and Medicine: What's in Your Genome? (MIT)

Description

Human genome sequencing has revolutionized our understanding of disease susceptibility, drug metabolism and human ancestry. This course will explore how these advances have been made possible by revolutionary new sequencing methodologies that have decreased costs and increased throughput of genome analysis, making it possible to examine genetic correlates for a variety of biological processes and disorders. The course will combine discussions of primary scientific research papers with hands-on data analysis and small group presentations. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a

Subjects

genome sequencing | genome analysis | disease susceptibility | drug metabolism | human ancestry | mitochondrial DNA | tyrosine kinase inhibitors | BCR-ABL gene fusion | PCSK9 inhibitors | hypercholesterolemia | genetic testing | next generation sequencing | Single-nucleotide polymorphisms (SNPs) | copy number variations (CNVs) | genome-wide association studies (GWAS) | Chronic myelogenous leukemia (CML) | mosaics | chimeras | bioinformatics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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