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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | BE.370 | BE.370 | BE.470 | BE.470 | HST.541 | HST.541

License

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2.500 Desalination and Water Purification (MIT) 2.500 Desalination and Water Purification (MIT)

Description

Water supply is a problem of worldwide concern: more than 1 billion people do not have reliable access to clean drinking water. Water is a particular problem for the developing world, but scarcity also impacts industrial societies. Water purification and desalination technology can be used to convert brackish ground water or seawater into drinking water. The challenge is to do so sustainably, with minimum cost and energy consumption, and with appropriately accessible technologies. This subject will survey the state-of-the-art in water purification by desalination and filtration. Fundamental thermodynamic and transport processes which govern the creation of fresh water from seawater and brackish ground water will be developed. The technologies of existing desalination systems will be discus Water supply is a problem of worldwide concern: more than 1 billion people do not have reliable access to clean drinking water. Water is a particular problem for the developing world, but scarcity also impacts industrial societies. Water purification and desalination technology can be used to convert brackish ground water or seawater into drinking water. The challenge is to do so sustainably, with minimum cost and energy consumption, and with appropriately accessible technologies. This subject will survey the state-of-the-art in water purification by desalination and filtration. Fundamental thermodynamic and transport processes which govern the creation of fresh water from seawater and brackish ground water will be developed. The technologies of existing desalination systems will be discus

Subjects

reverse osmosis | reverse osmosis | seawater | seawater | electrodialysis | electrodialysis | student work | student work | distillation | distillation | flash evaporation | flash evaporation | power generation | power generation | wastewater treatment | wastewater treatment | particulate removal | particulate removal | system engineering | system engineering | cogeneration | cogeneration | solar still | solar still | chlorination | chlorination | Haiti | Haiti

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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6.021J Quantitative Physiology: Cells and Tissues (MIT) 6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i

Subjects

quantitative physiology | quantitative physiology | cells | cells | tissues | tissues | mass transport | mass transport | electrical signal generation | electrical signal generation | biological membranes | biological membranes | membranes | membranes | diffusion | diffusion | osmosis | osmosis | chemically mediated transport | chemically mediated transport | active transport | active transport | ion transport | ion transport | equilibrium potential | equilibrium potential | resting potential | resting potential | action potential | action potential | voltage-gated ion channels | voltage-gated ion channels | 6.021 | 6.021 | 2.791 | 2.791 | 2.794 | 2.794 | 6.521 | 6.521 | 20.370 | 20.370 | 20.470 | 20.470 | HST.541 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.32 Separation Processes (MIT) 10.32 Separation Processes (MIT)

Description

This course covers the general principles of separation by equilibrium and rate processes. Topics include staged cascades and applications to distillation, absorption, adsorption, and membrane processes. Phase equilibria and the role of diffusion are also covered. This course covers the general principles of separation by equilibrium and rate processes. Topics include staged cascades and applications to distillation, absorption, adsorption, and membrane processes. Phase equilibria and the role of diffusion are also covered.

Subjects

separation process | separation process | chemical mixtures | chemical mixtures | biological mixtures | biological mixtures | distillation | distillation | membrane processes | membrane processes | chromatography | chromatography | adsorption | adsorption | precipitation | precipitation | crystallization | crystallization | filtration | filtration | membrane filtration | membrane filtration | fixed bed adsorption | fixed bed adsorption | reverse osmosis | reverse osmosis | McCabe-Thiele | McCabe-Thiele | stripping | stripping | equilibrium | equilibrium | rate processes | rate processes | staged cascades | staged cascades | absorption | absorption | phase equilibria | phase equilibria | diffusion | diffusion

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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20.330J Fields, Forces and Flows in Biological Systems (MIT) 20.330J Fields, Forces and Flows in Biological Systems (MIT)

Description

This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics. This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics.

Subjects

hydrodynamic flow | hydrodynamic flow | electroosmosis | electroosmosis | diffusion | diffusion | electrophoresis | electrophoresis | reaction | reaction | membrane | membrane | cell | cell | biomolecule | biomolecule | microfluidics | microfluidics | ion transport | ion transport | electrokinetics | electrokinetics | Debye layer | Debye layer | Zeta potential | Zeta potential | inviscid flow | inviscid flow | viscous flow | viscous flow | tissue | tissue | organ | organ | biology | biology | molecular biology | molecular biology | Maxwell's equations | Maxwell's equations | electro-quasistatics | electro-quasistatics | Van der Waals | Van der Waals | bioMEMS | bioMEMS

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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HST.410J Projects in Microscale Engineering for the Life Sciences (MIT) HST.410J Projects in Microscale Engineering for the Life Sciences (MIT)

Description

This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling. In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building. This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling. In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building.

Subjects

HST.410 | HST.410 | 6.07 | 6.07 | cell manipulation | cell manipulation | microchips | microchips | lithography | lithography | rapid prototyping | rapid prototyping | optical imaging of cells | optical imaging of cells | cell sorting | cell sorting | microfluidics | microfluidics | osmosis | osmosis | diffusion | diffusion | microfabrication | microfabrication | models of diffusion | models of diffusion | laminar flow | laminar flow | MATLAB data analysis | MATLAB data analysis | cell traps | cell traps | experimental design | experimental design | cytometry techniques | cytometry techniques | computer simulation of neural behavior | computer simulation of neural behavior | casting PDMS | casting PDMS | coulter counter | coulter counter | plasma bonding | plasma bonding

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Concentration Gradients

Description

This RLO describes the concept of concentration gradients in biological systems through analogy with gradients found in everyday life, and outlines passive and active transport across cell membranes.

Subjects

concentration gradient | cell membrane | active transport | passive transport | osmosis | foundation science | Physical Sciences | Biological Sciences | Biological sciences | Physical sciences | C000 | F000

License

Attribution-Share Alike 2.0 UK: England & Wales Attribution-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-sa/2.0/uk/ http://creativecommons.org/licenses/by-sa/2.0/uk/

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Starling's Forces

Description

An examination of the roles of hydrostatic and oncotic pressure in movement of fluid and gases across the capillary wall.

Subjects

osmosis | diffusion | respiration | oncotic pressure | hydrostatic pressure | foundation science | Physical Sciences | Physical sciences | F000

License

Attribution-Share Alike 2.0 UK: England & Wales Attribution-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-sa/2.0/uk/ http://creativecommons.org/licenses/by-sa/2.0/uk/

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Kidney function and dysfunction - Osmosis

Description

Powerpoint presentation on Osmosis - The movement of water into and out of cells. Two animations (swf) showing the effect of different solute concentrations.

Subjects

osmosis | kidney function | powerpoint | presentation | animation | swf | dysfunction | ppt | SCIENCES and MATHEMATICS | R

License

Attribution-Noncommercial 2.0 UK: England & Wales Attribution-Noncommercial 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc/2.0/uk/ http://creativecommons.org/licenses/by-nc/2.0/uk/

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Kidney function and dysfunction - The function of the kidney

Description

Powerpoint presentation: The function of the kidney, with a Gap filled exercise.

Subjects

kidney function | osmosis | dysfunction | quiz | gap fill exercise | powerpoint | ppt | SCIENCES and MATHEMATICS | R

License

Attribution-Noncommercial 2.0 UK: England & Wales Attribution-Noncommercial 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc/2.0/uk/ http://creativecommons.org/licenses/by-nc/2.0/uk/

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Ion channels

Description

radiographers).

Subjects

Pharmacology | pharmacodynamics | osmosis

License

Copyright Oxford Brookes University, all rights reserved Copyright Oxford Brookes University, all rights reserved

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6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

This course is jointly offered through four departments, available to both undergraduates and graduates. This course introduces the principles of mass transport and electrical signal generation for biological membranes, cells, and tissues. Topics covered include: mass transport through membranes (diffusion, osmosis, chemically mediated, and active transport), electric properties of cells (ion transport), equilibrium, resting, and action potentials, kinetic and molecular properties of single voltage-gated ion channels. Laboratory and computer exercises illustrate the course concepts. Students engage in extensive written and oral communication exercises. This course is worth 4 Engineering Design Points.Technical RequirementsMATLAB® software is required to run the .m files f

Subjects

quantitative physiology | cells | tissues | mass transport | electrical signal generation | biological membranes | membranes | diffusion | osmosis | chemically mediated transport | active transport | ion transport | 6.021 | 2.791 | 2.794 | 6.521 | BE.370 | BE.470 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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2.500 Desalination and Water Purification (MIT)

Description

Water supply is a problem of worldwide concern: more than 1 billion people do not have reliable access to clean drinking water. Water is a particular problem for the developing world, but scarcity also impacts industrial societies. Water purification and desalination technology can be used to convert brackish ground water or seawater into drinking water. The challenge is to do so sustainably, with minimum cost and energy consumption, and with appropriately accessible technologies. This subject will survey the state-of-the-art in water purification by desalination and filtration. Fundamental thermodynamic and transport processes which govern the creation of fresh water from seawater and brackish ground water will be developed. The technologies of existing desalination systems will be discus

Subjects

reverse osmosis | seawater | electrodialysis | student work | distillation | flash evaporation | power generation | wastewater treatment | particulate removal | system engineering | cogeneration | solar still | chlorination | Haiti

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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20.330J Fields, Forces and Flows in Biological Systems (MIT)

Description

This course introduces the basic driving forces for electric current, fluid flow, and mass transport, plus their application to a variety of biological systems. Basic mathematical and engineering tools will be introduced, in the context of biology and physiology. Various electrokinetic phenomena are also considered as an example of coupled nature of chemical-electro-mechanical driving forces. Applications include transport in biological tissues and across membranes, manipulation of cells and biomolecules, and microfluidics.

Subjects

hydrodynamic flow | electroosmosis | diffusion | electrophoresis | reaction | membrane | cell | biomolecule | microfluidics | ion transport | electrokinetics | Debye layer | Zeta potential | inviscid flow | viscous flow | tissue | organ | biology | molecular biology | Maxwell's equations | electro-quasistatics | Van der Waals | bioMEMS

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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HST.410J Projects in Microscale Engineering for the Life Sciences (MIT)

Description

This course is a project-based introduction to manipulating and characterizing cells and biological molecules using microfabricated tools. It is designed for first year undergraduate students. In the first half of the term, students perform laboratory exercises designed to introduce (1) the design, manufacture, and use of microfluidic channels, (2) techniques for sorting and manipulating cells and biomolecules, and (3) making quantitative measurements using optical detection and fluorescent labeling. In the second half of the term, students work in small groups to design and test a microfluidic device to solve a real-world problem of their choosing. Includes exercises in written and oral communication and team building.

Subjects

HST.410 | 6.07 | cell manipulation | microchips | lithography | rapid prototyping | optical imaging of cells | cell sorting | microfluidics | osmosis | diffusion | microfabrication | models of diffusion | laminar flow | MATLAB data analysis | cell traps | experimental design | cytometry techniques | computer simulation of neural behavior | casting PDMS | coulter counter | plasma bonding

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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6.021J Quantitative Physiology: Cells and Tissues (MIT)

Description

In this subject, we consider two basic topics in cellular biophysics, posed here as questions: Which molecules are transported across cellular membranes, and what are the mechanisms of transport? How do cells maintain their compositions, volume, and membrane potential? How are potentials generated across the membranes of cells? What do these potentials do? Although the questions posed are fundamentally biological questions, the methods for answering these questions are inherently multidisciplinary. As we will see throughout the course, the role of mathematical models is to express concepts precisely enough that precise conclusions can be drawn. In connection with all the topics covered, we will consider both theory and experiment. For the student, the educational value of examining the i

Subjects

quantitative physiology | cells | tissues | mass transport | electrical signal generation | biological membranes | membranes | diffusion | osmosis | chemically mediated transport | active transport | ion transport | equilibrium potential | resting potential | action potential | voltage-gated ion channels | 6.021 | 2.791 | 2.794 | 6.521 | 20.370 | 20.470 | HST.541

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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10.32 Separation Processes (MIT)

Description

This course covers the general principles of separation by equilibrium and rate processes. Topics include staged cascades and applications to distillation, absorption, adsorption, and membrane processes. Phase equilibria and the role of diffusion are also covered.

Subjects

separation process | chemical mixtures | biological mixtures | distillation | membrane processes | chromatography | adsorption | precipitation | crystallization | filtration | membrane filtration | fixed bed adsorption | reverse osmosis | McCabe-Thiele | stripping | equilibrium | rate processes | staged cascades | absorption | phase equilibria | diffusion

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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