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7.340 Under the Radar Screen: How Bugs Trick Our Immune Defenses (MIT) 7.340 Under the Radar Screen: How Bugs Trick Our Immune Defenses (MIT)

Description

In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about

Subjects

HIV | HIV | mycobacterium tuberculosis | mycobacterium tuberculosis | malaria | malaria | influenza | influenza | immune system | immune system | pathogens | pathogens | viruses | viruses | bacteria | bacteria | parasites | parasites | microbes | microbes | phagocytosis | phagocytosis | ubiquitin/proteasome pathway | ubiquitin/proteasome pathway | MHC I/II antigen presentation | MHC I/II antigen presentation | Salmonella | Salmonella | pathogen-associated molecular patterns | pathogen-associated molecular patterns | PAMP | PAMP | Toll-like receptors | Toll-like receptors | TLR | TLR | Vaccinia virus | Vaccinia virus | Proteasome | Proteasome | Ubiquitin; deubiquinating enzymes | Ubiquitin; deubiquinating enzymes | DUB | DUB | Herpes simplex virus | Herpes simplex virus | HSV | HSV | Yersinia | Yersinia | viral budding | viral budding | Human cytomegalovirus | Human cytomegalovirus | HCMV | HCMV | Histocompatiblity | Histocompatiblity | AIDS | AIDS | Kaposi Sarcoma-Associated Herpes virus | Kaposi Sarcoma-Associated Herpes virus | Mixoma virus | Mixoma virus | Epstein Barr virus | Epstein Barr virus | EBV | EBV | Burkitt?s B cell lymphoma | Burkitt?s B cell lymphoma

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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6.891 Computational Evolutionary Biology (MIT) 6.891 Computational Evolutionary Biology (MIT)

Description

Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data. Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data.

Subjects

evolution from a computational | evolution from a computational | modeling | modeling | and engineering perspective | and engineering perspective | analyzing evolutionary data | analyzing evolutionary data | vaccine | vaccine | polio | polio | influenza | influenza | AIDS | AIDS | evolutionary extinction | evolutionary extinction | sex | sex | parasites | parasites | modern genomics | modern genomics | polio vaccine | polio vaccine | hands-on | hands-on | evolution from a computational | modeling | and engineering perspective | evolution from a computational | modeling | and engineering perspective

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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RJN0001PM0019

Description

Parasitic lession in sheep liver.

Subjects

sheep | liver | parasites | pathology | postmortem | vph | svmsvet

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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RJN0001PM0018

Description

Parasitic lession in sheep liver.

Subjects

sheep | liver | parasites | pathology | postmortem | vph | svmsvet

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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Toxins and Viruses

Description

This resources looks at the potential risks of food contamination coming from toxins and viruses.

Subjects

Toxins | viruses | fish | shell fish | plant toxins | bacteria | hazards | mould | fungi | parasites | mycotoxin | aflatoxin | Norwalk | hygiene | personal hygiene | safe food handling practices | food handling practices | daily routine | catering | HACCP | basic food hygiene | NVQ Level 2 | oxb:200811:009PJ | sport | leisure | tourism | hospitality | cc-by | creative commons | UKOER | HLST | ENGSCOER | OER | LL2012 | London 2012 | Olympics | Olympic Games | Paralympics | Paralympic Games | Learning Legacies | JISC | HEA | Oxford Brookes University | HLSTOER.

License

This work is licensed under a Creative Commons Attribution 2.0 UK: England and Wales License,except where otherwise noted within the resource. This work is licensed under a Creative Commons Attribution 2.0 UK: England and Wales License,except where otherwise noted within the resource.

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Toxins and viruses

Description

This resources looks at the potential risks of food contamination coming from toxins and viruses

Subjects

viruses | fish | shell fish | plant toxins | bacteria | hazards | mould | fungi | parasites | mycotoxin | aflatoxin | hygiene | personal hygiene | safe food handling practices | food handling practices | daily routine | catering | basic food hygiene | sport | leisure | tourism | hospitality | cc-by | creative commons | toxins | norwalk | haccp | nvq level 2 | oxb:200811:009pj | ukoer | hlst | engscoer | oer | ll2012 | london 2012 | olympics | olympic games | paralympics | paralympic games | learning legacies | jisc | hea | oxford brookes university | hlstoer | CATERING / FOOD / LEISURE SERVICES / TOURISM | N

License

Attribution 2.0 UK: England & Wales Attribution 2.0 UK: England & Wales http://creativecommons.org/licenses/by/2.0/uk/ http://creativecommons.org/licenses/by/2.0/uk/

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RJN0001PM0034

Description

Parasitic lesion in sheep diaphragm.

Subjects

sheep | diaphragm | parasites | pathology | postmortem | vph | svmsvet

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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RJN0001PM0021

Description

Parasitic lesion in sheep liver.

Subjects

sheep | liver | parasites | pathology | postmortem | vph | svmsvet

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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Curated collection of Microbiology resources

Description

This is an evaluated collection of links to resources for learning and teaching subjects relating to Microbiology. This forms part of the UK Centre for Bioscience OeRBITAL project.

Subjects

ukoer | oerbital | microbiology | fungi | mycology | parasites | parasitology | viruses | virology | Biological sciences | C000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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RJN0001PM0020

Description

Parasitic lession in sheep liver.

Subjects

sheep | liver | parasites | pathology | postmortem | vph | svmsvet

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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E0000P0142

Description

Container of Closamectin

Subjects

svmsvet | closamectin | injection | wormer | antiparasiticide | fluke | external | parasites | farm

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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RVC/FAO Guide to Veterinary Diagnostic Parasitology

Description

The ‘RVC/FAO Guide to Veterinary Diagnostic Parasitology ‘is a collaborative project which provides a user-friendly computer-aided educational tool for lecturers in both the UK in the developing world. It focuses on the faecal examination of farm animals for helminth parasites. The techniques outlined in the program are designed for basic training and arranged to take the user step-by step through the procedures. Details of their application, limitations and guidelines for health and safety requirements are included. Its intended learner profile is BVM Year 3 and it is linked to the year’s parasitology practical on worm egg identification; students are encouraged to visit the resource as it constitutes a recommended preparation for this practical.

Subjects

veterinary medicine | parasites | diagnostic parasitology | helminths | faecal examination | ukoer | ooer | medev | rvc | related subjects | D000

License

Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-nd/2.0/uk/ http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

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RJN0000PC0056

Description

Working with the community in knowledge transfer. Focusing in parasites, parasitic diseases and zoonoses. Daniela, Universidad de Concepcion, Chilan, Chile (www.veterinariaudec.cl/‎)

Subjects

parasites | knowledgetransfer | svmsvet | chillan | chile | vph

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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E0000P0142

Description

Container of Closamectin

Subjects

svmsvet | closamectin | injection | wormer | antiparasiticide | fluke | external | parasites | farm

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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RJN0000PC0056

Description

Working with the community in knowledge transfer. Focusing in parasites, parasitic diseases and zoonoses. Daniela, Universidad de Concepcion, Chilan, Chile (www.veterinariaudec.cl/?)

Subjects

parasites | knowledgetransfer | svmsvet | chillan | chile | vph

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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7.341 Host Hacking: Parasitic Manipulations from a Micro- to a Macroscopic Scale (MIT)

Description

Parasites require a hospitable organism to reproduce and spread and have evolved multiple strategies to subvert their hosts. Parasites scavenge nutrients directly from host cells, evade the host immune system and even modify host behavior to increase their transmission. This course will explore the strategies used by a ubiquitous and harmful class of parasites to hijack the biology of their host cells. We will discuss pathogens such as Plasmodium and Toxoplasma, responsible for some of the deadliest and most pervasive infectious diseases on the planet.By exploring how these pathogens invade a host cell and replicate while evading the immune system, students will gain a broad understanding of basic cell biology, biochemistry and immunology, as well as learn techniques commonly used in cell

Subjects

parasites | host | Plasmodium | Toxoplasma | malaria | molecular parasitology | Toxoplasma gondii | Plasmodium falciparum | PTEX | Theileria | PfEMP1

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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7.340 Under the Radar Screen: How Bugs Trick Our Immune Defenses (MIT)

Description

In this course, we will explore the specific ways by which microbes defeat our immune system and the molecular mechanisms that are under attack (phagocytosis, the ubiquitin/proteasome pathway, MHC I/II antigen presentation). Through our discussion and dissection of the primary research literature, we will explore aspects of host-pathogen interactions. We will particularly emphasize the experimental techniques used in the field and how to read and understand research data. Technological advances in the fight against microbes will also be discussed, with specific examples. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about

Subjects

HIV | mycobacterium tuberculosis | malaria | influenza | immune system | pathogens | viruses | bacteria | parasites | microbes | phagocytosis | ubiquitin/proteasome pathway | MHC I/II antigen presentation | Salmonella | pathogen-associated molecular patterns | PAMP | Toll-like receptors | TLR | Vaccinia virus | Proteasome | Ubiquitin; deubiquinating enzymes | DUB | Herpes simplex virus | HSV | Yersinia | viral budding | Human cytomegalovirus | HCMV | Histocompatiblity | AIDS | Kaposi Sarcoma-Associated Herpes virus | Mixoma virus | Epstein Barr virus | EBV | Burkitt?s B cell lymphoma

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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RJN0000DRM0001

Description

Screw worm eggs on a dogs ear. For more information in screw worm please follow the link: www.cfsph.iastate.edu/Factsheets/pdfs/screwworm_myiasis.pdf

Subjects

dog | screwworm | myasis | parasites | svmsvet | vph

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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6.891 Computational Evolutionary Biology (MIT)

Description

Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data.

Subjects

evolution from a computational | modeling | and engineering perspective | analyzing evolutionary data | vaccine | polio | influenza | AIDS | evolutionary extinction | sex | parasites | modern genomics | polio vaccine | hands-on | evolution from a computational | modeling | and engineering perspective

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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6.891 Computational Evolutionary Biology (MIT)

Description

Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data.

Subjects

evolution from a computational | modeling | and engineering perspective | analyzing evolutionary data | vaccine | polio | influenza | AIDS | evolutionary extinction | sex | parasites | modern genomics | polio vaccine | hands-on | evolution from a computational | modeling | and engineering perspective

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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RJN0000DRM0001

Description

Screw worm eggs on a dogs ear. For more information in screw worm please follow the link: www.cfsph.iastate.edu/Factsheets/pdfs/screwworm_myiasis.pdf

Subjects

dog | screwworm | myasis | parasites | svmsvet | vph

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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Toxins and Viruses

Description

This resources looks at the potential risks of food contamination coming from toxins and viruses.

Subjects

Toxins | viruses | fish | shell fish | plant toxins | bacteria | hazards | mould | fungi | parasites | mycotoxin | aflatoxin | Norwalk | hygiene | personal hygiene | safe food handling practices | food handling practices | daily routine | catering | HACCP | basic food hygiene | NVQ Level 2 | oxb:200811:009PJ | sport | leisure | tourism | hospitality | cc-by | creative commons | UKOER | HLST | ENGSCOER | OER | LL2012 | London 2012 | Olympics | Olympic Games | Paralympics | Paralympic Games | Learning Legacies | JISC | HEA | Oxford Brookes University | HLSTOER.

License

Creative Commons Licence
This work is licensed under a Creative Commons Attribution 2.0 UK: England & Wales License, except where otherwise noted within the resource. This work is licensed under a Creative Commons Attribution 2.0 UK: England & Wales License, except where otherwise noted within the resource.

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