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2.782J Design of Medical Devices and Implants (MIT) 2.782J Design of Medical Devices and Implants (MIT)

Description

Solution of clinical problems by use of implants and other medical devices. Systematic use of cell-matrix control volumes. The role of stress analysis in the design process. Anatomic fit: shape and size of implants. Selection of biomaterials. Instrumentation for surgical implantation procedures. Preclinical testing for safety and efficacy: risk/benefit ratio assessment. Evaluation of clinical performance: design of clinical trials. Project materials drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants. Solution of clinical problems by use of implants and other medical devices. Systematic use of cell-matrix control volumes. The role of stress analysis in the design process. Anatomic fit: shape and size of implants. Selection of biomaterials. Instrumentation for surgical implantation procedures. Preclinical testing for safety and efficacy: risk/benefit ratio assessment. Evaluation of clinical performance: design of clinical trials. Project materials drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Subjects

clinical problems | clinical problems | implants | implants | medical devices | medical devices | cell-matrix control volumes | cell-matrix control volumes | stress analysis | stress analysis | Anatomic fit | Anatomic fit | biomaterials | biomaterials | surgical implantation procedures | surgical implantation procedures | Preclinical testing | Preclinical testing | risk/benefit ratio assessment | risk/benefit ratio assessment | clinical performance | clinical performance | clinical trials | clinical trials | orthopedic devices | orthopedic devices | soft tissue implants | soft tissue implants | artificial organs | artificial organs | dental implants | dental implants | BE.451J | BE.451J | 2.782 | 2.782 | 3.961 | 3.961 | BE.451 | BE.451 | HST.524 | HST.524 | 20.451 | 20.451

License

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2.782J Design of Medical Devices and Implants (MIT) 2.782J Design of Medical Devices and Implants (MIT)

Description

This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants. This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Subjects

2.782 | 2.782 | 3.961 | 3.961 | 20.451 | 20.451 | HST.524 | HST.524 | clinical problems | clinical problems | implants | implants | medical devices | medical devices | cell-matrix control volumes | cell-matrix control volumes | stress analysis | stress analysis | anatomic fit | anatomic fit | biomaterials | biomaterials | surgical implantation procedures | surgical implantation procedures | Preclinical testing | Preclinical testing | risk/benefit ratio assessment | risk/benefit ratio assessment | clinical performance | clinical performance | clinical trials | clinical trials | orthopedic devices | orthopedic devices | soft tissue implants | soft tissue implants | artificial organs | artificial organs | dental implants | dental implants | stent | stent | prosthesis | prosthesis | scaffold | scaffold | bio-implant | bio-implant | scar | scar | genetics | genetics | skin | skin | nerve | nerve | bone | bone | tooth | tooth | joint | joint | FDA | FDA | FDA approval | FDA approval | cartilage | cartilage | ACL | ACL | health | health | regulation | regulation | healthcare | healthcare | medicine | medicine | bioengineering | bioengineering

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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20.441 Biomaterials-Tissue Interactions (BE.441) (MIT) 20.441 Biomaterials-Tissue Interactions (BE.441) (MIT)

Description

This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to

Subjects

medical implants | medical implants | artificial organs | artificial organs | tissue engineering | tissue engineering | matrix | matrix | biomaterials | biomaterials | protein adsorption | protein adsorption | unit cell process | unit cell process | wound healing | wound healing | tissue remodeling | tissue remodeling | tissue regeneration | tissue regeneration | organ regeneration | organ regeneration | prosthesis | prosthesis | biodegradable | biodegradable | bioreplaceable implants | bioreplaceable implants | BE.441 | BE.441 | 2.79 | 2.79 | 3.96 | 3.96 | HST.522 | HST.522

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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BE.441 Biomaterials-Tissue Interactions (MIT) BE.441 Biomaterials-Tissue Interactions (MIT)

Description

This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to

Subjects

medical implants | medical implants | artificial organs | artificial organs | tissue engineering | tissue engineering | matrix | matrix | biomaterials | biomaterials | protein adsorption | protein adsorption | unit cell process | unit cell process | wound healing | wound healing | tissue remodeling | tissue remodeling | tissue regeneration | tissue regeneration | organ regeneration | organ regeneration | prosthesis | prosthesis | biodegradable | biodegradable | bioreplaceable implants | bioreplaceable implants | 2.79J | 2.79J | 3.96J | 3.96J | HST.522J | HST.522J | 2.79 | 2.79 | 3.96 | 3.96 | HST.522 | HST.522

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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3.032 Mechanical Behavior of Materials (MIT) 3.032 Mechanical Behavior of Materials (MIT)

Description

Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, and fracture of materials including crystalline and amorphous metals, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. Integrated laboratories provide the opportunity to explore these concepts through hands-on experiments including instrumentation of pressure vessels, visualization of atomistic deformation in bubble rafts, nanoindentation, and uniaxial mechanical testing, as well as writing assignments to communicate th Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, and fracture of materials including crystalline and amorphous metals, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. Integrated laboratories provide the opportunity to explore these concepts through hands-on experiments including instrumentation of pressure vessels, visualization of atomistic deformation in bubble rafts, nanoindentation, and uniaxial mechanical testing, as well as writing assignments to communicate th

Subjects

Basic concepts of solid mechanics and mechanical behavior of materials | Basic concepts of solid mechanics and mechanical behavior of materials | stress-strain relationships | stress-strain relationships | stress transformation | stress transformation | elasticity | elasticity | plasticity and fracture. Case studies include materials selection for bicycle frames | plasticity and fracture. Case studies include materials selection for bicycle frames | stress shielding in biomedical implants; residual stresses in thin films; and ancient materials. Lab experiments and demonstrations give hands-on experience of the physical concepts at a variety of length scales. Use of facilities for measuring mechanical properties including standard mechanical tests | stress shielding in biomedical implants; residual stresses in thin films; and ancient materials. Lab experiments and demonstrations give hands-on experience of the physical concepts at a variety of length scales. Use of facilities for measuring mechanical properties including standard mechanical tests | bubble raft models | bubble raft models | atomic force microscopy and nanoindentation. | atomic force microscopy and nanoindentation. | plasticity and fracture | plasticity and fracture | Case studies | Case studies | materials selection | materials selection | bicycle frames | bicycle frames | stress shielding in biomedical implants | stress shielding in biomedical implants | residual stresses in thin films | residual stresses in thin films | ancient materials | ancient materials | standard mechanical tests | standard mechanical tests | solid mechanics | solid mechanics | mechanical behavior of materials | mechanical behavior of materials

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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16.422 Human Supervisory Control of Automated Systems (MIT) 16.422 Human Supervisory Control of Automated Systems (MIT)

Description

Human Supervisory Control of Automated Systems discusses elements of the interactions between humans and machines.  These elements include: assignment of roles and authority; tradeoffs between human control and human monitoring; and human intervention in automatic processes.  Further topics comprise: performance, optimization and social implications of the system; enhanced human interfaces; decision aiding; and automated alterting systems.  Topics refer to applications in aerospace, industrial and transportation systems. Human Supervisory Control of Automated Systems discusses elements of the interactions between humans and machines.  These elements include: assignment of roles and authority; tradeoffs between human control and human monitoring; and human intervention in automatic processes.  Further topics comprise: performance, optimization and social implications of the system; enhanced human interfaces; decision aiding; and automated alterting systems.  Topics refer to applications in aerospace, industrial and transportation systems.

Subjects

Human supervisory control | Human supervisory control | Dynamic systems | Dynamic systems | Complex dynamic systems | Complex dynamic systems | Automation | Automation | Automated systems | Automated systems | Decision processes | Decision processes | Man-machine | Man-machine | Supervisory functions | Supervisory functions | Human-centered | Human-centered | Systems engineering design | Systems engineering design | Semi-structured models | Semi-structured models | Tast analysis | Tast analysis | Function allocation | Function allocation | Memory | Memory | Attention | Attention | Classical decision theory | Classical decision theory | Signal detection | Signal detection | Uncertainty | Uncertainty | Naturalistic decision making | Naturalistic decision making | Workload | Workload | Situation awareness | Situation awareness | Aircraft displays | Aircraft displays | Flight management systems | Flight management systems | Human error | Human error | Reliability | Reliability | Cooperative decision support | Cooperative decision support | Adaptive automation | Adaptive automation | Alerting systems | Alerting systems | Command and control | Command and control | Air traffic control | Air traffic control | Unmanned space vehicles | Unmanned space vehicles | Automobile systems | Automobile systems | Telemedicine | Telemedicine | Telerobotics | Telerobotics | Medical interface design | Medical interface design | Nuclear control plants | Nuclear control plants | Process control plants | Process control plants

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Industrial utilization of medicinal and aromatic plants Industrial utilization of medicinal and aromatic plants

Description

Medicinal aromatic plants belong to a big plant group with a great interest due to its pharmaceutical, cosmetic and nutritional application. In addition, they are also an alternative to traditional crop with species in high demand at the current international market. It is expected to provide basic knowledge and skills related to production and chemical features of essences and extracts from local plants in Iberian Peninsula. The main purpose of this course is that students have an approach to economical importance, uses, botany and harvested processes of the most significant medicinal aromatic and seasoning specie plants. The objectives of this course are: * To classify and identify aromatic plant, seasonings and medicinal plant. * To understand cultivation techniques and effe Medicinal aromatic plants belong to a big plant group with a great interest due to its pharmaceutical, cosmetic and nutritional application. In addition, they are also an alternative to traditional crop with species in high demand at the current international market. It is expected to provide basic knowledge and skills related to production and chemical features of essences and extracts from local plants in Iberian Peninsula. The main purpose of this course is that students have an approach to economical importance, uses, botany and harvested processes of the most significant medicinal aromatic and seasoning specie plants. The objectives of this course are: * To classify and identify aromatic plant, seasonings and medicinal plant. * To understand cultivation techniques and effe

Subjects

Ingeniería Agroforestal | Ingeniería Agroforestal | medicinal plants | medicinal plants | aromatic plants | aromatic plants | extracts | extracts | active principles | active principles | essential oils | essential oils

License

Copyright 2009, by the Contributing Authors http://creativecommons.org/licenses/by-nc-sa/3.0/

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Elec. Light - Ice Plant And - Water Works. Arlington Tex. Elec. Light - Ice Plant And - Water Works. Arlington Tex.

Description

Subjects

streets | streets | cities | cities | towns | towns | rppc | rppc | electricpowerplants | electricpowerplants | hydroelectricpowerplants | hydroelectricpowerplants

License

No known copyright restrictions

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Fashion model - Fort Lauderdale Fashion model - Fort Lauderdale

Description

Subjects

plants | plants | beer | beer | fashion | fashion | bars | bars | florida | florida | models | models | liquor | liquor | pottedplants | pottedplants | fortlauderdale | fortlauderdale | leopardskinfabric | leopardskinfabric

License

No known copyright restrictions

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2.782J Design of Medical Devices and Implants (MIT)

Description

Solution of clinical problems by use of implants and other medical devices. Systematic use of cell-matrix control volumes. The role of stress analysis in the design process. Anatomic fit: shape and size of implants. Selection of biomaterials. Instrumentation for surgical implantation procedures. Preclinical testing for safety and efficacy: risk/benefit ratio assessment. Evaluation of clinical performance: design of clinical trials. Project materials drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Subjects

clinical problems | implants | medical devices | cell-matrix control volumes | stress analysis | Anatomic fit | biomaterials | surgical implantation procedures | Preclinical testing | risk/benefit ratio assessment | clinical performance | clinical trials | orthopedic devices | soft tissue implants | artificial organs | dental implants | BE.451J | 2.782 | 3.961 | BE.451 | HST.524 | 20.451

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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2.782J Design of Medical Devices and Implants (MIT)

Description

This design course targets the solution of clinical problems by use of implants and other medical devices. Topics include the systematic use of cell-matrix control volumes; the role of stress analysis in the design process; anatomic fit, shape and size of implants; selection of biomaterials; instrumentation for surgical implantation procedures; preclinical testing for safety and efficacy, including risk/benefit ratio assessment evaluation of clinical performance and design of clinical trials. Student project materials are drawn from orthopedic devices, soft tissue implants, artificial organs, and dental implants.

Subjects

2.782 | 3.961 | 20.451 | HST.524 | clinical problems | implants | medical devices | cell-matrix control volumes | stress analysis | anatomic fit | biomaterials | surgical implantation procedures | Preclinical testing | risk/benefit ratio assessment | clinical performance | clinical trials | orthopedic devices | soft tissue implants | artificial organs | dental implants | stent | prosthesis | scaffold | bio-implant | scar | genetics | skin | nerve | bone | tooth | joint | FDA | FDA approval | cartilage | ACL | health | regulation | healthcare | medicine | bioengineering

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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21H.421 Introduction to Environmental History (MIT) 21H.421 Introduction to Environmental History (MIT)

Description

This seminar provides a historical overview of the interactions between people and their environments. Focusing primarily on the experience of Europeans in the period after Columbus, the subject explores the influence of nature (climate, topography, plants, animals, and microorganisms) on human history and the reciprocal influence of people on nature. Topics include the biological consequences of the European encounter with the Americas, the environmental impact of technology, and the roots of the current environmental crisis. This seminar provides a historical overview of the interactions between people and their environments. Focusing primarily on the experience of Europeans in the period after Columbus, the subject explores the influence of nature (climate, topography, plants, animals, and microorganisms) on human history and the reciprocal influence of people on nature. Topics include the biological consequences of the European encounter with the Americas, the environmental impact of technology, and the roots of the current environmental crisis.

Subjects

environmental history | environmental history | europe | europe | columbus | columbus | climate | climate | topography | topography | nature | nature | plants | plants | animals | animals | microorganisms | microorganisms | human history | human history | americas | americas | technology impact | technology impact | crisis | crisis | wilderness | wilderness | garden | garden | science | science | landscape | landscape | agriculture | agriculture | poison | poison | conservation | conservation | preservation | preservation | demography | demography | industry | industry

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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9.14 Brain Structure and its Origins (MIT) 9.14 Brain Structure and its Origins (MIT)

Description

This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity. This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Development | Development

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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HST.723 Neural Coding and Perception of Sound (MIT) HST.723 Neural Coding and Perception of Sound (MIT)

Description

Neural structures and mechanisms mediating the detection, localization and recognition of sounds. We will discuss how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants. Neural structures and mechanisms mediating the detection, localization and recognition of sounds. We will discuss how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants.

Subjects

hearing | hearing | neural structures | neural structures | auditory masking | auditory masking | acoustics | acoustics | signal transformations | signal transformations | temporal coding | temporal coding | neural maps | neural maps | feature detectors | feature detectors | learning | learning | plasticity | plasticity | feedback control | feedback control | sound localization | sound localization | musical pitch | musical pitch | speech coding | speech coding | cochlear implants | cochlear implants

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Development of the Mammalian Brain (MIT) Development of the Mammalian Brain (MIT)

Description

Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Mammals -- Physiology | Mammals -- Physiology

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Manipulating plant genes - how do you actually do it?

Description

We often hear in the news about GM (Genetic Modification or Manipulation) but what does it actually involve? In this lecture Liam Dolan will explain how scientists go about manipulating the instruction manuals of plants with illustrations from his own research. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

plants | botany | biology | DNA | genetic modification | botanic gardens | GM | chemistry | plants | botany | biology | DNA | genetic modification | botanic gardens | GM | chemistry | 2011-10-24

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Achieving food security and sustainability for 9 billion

Description

To ensure food security for the increasing world population in a environmentally sustainable way, we must double productivity on the same area of land. as well as address the concerns of modern high input agriculture, declining water availability and climate change. Join us to hear Chris Leaver talk about the importance of investing in science and technology - essential tools in increasing the efficiency of agriculture and attempting to reverse the impact of man- made climate change. In his words 'Doing nothing is not an option' Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

plants | botany | food | Environment | sustainability | 9 billion | botanic gardens | population | plants | botany | food | Environment | sustainability | 9 billion | botanic gardens | population

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Plants in a chemical world

Description

Plants are able to metabolise a surprisingly diverse range of synthetic chemicals including pesticides and pollutants. These chemical reactions are important in global agriculture, as the ability of crops to metabolise herbicides rapidly is the primary determining factor in selective weed control in all our major cereals. In addition these chemical transformations are of general interest to consumers as they determine the fate, and toxicity, of residues entering the food chain. Join us to hear Rob Edwards (Food and Environment Agency Chief Scientist) talk about the mechanisms by which plants metabolise synthetic chemicals and recent progress in understanding the underpinning biology and biochemistry. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

plants | botany | biology | biochemistry | botanic gardens | chemistry | plants | botany | biology | biochemistry | botanic gardens | chemistry | 2011-11-07

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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From hairy roots to new medicines

Description

Modern medicine uses many compounds which are isolated from plants. For example, vinblastine, which is used to treat many types of cancer, is isolated from the leaves of the Madagascar periwinkle. Sarah O'Connor will talk about her work in understanding the process by which the plant makes this substance. Not only will this lead to cheaper vinblastine but also to the production of slightly modified versions of vinblastine which may have improved medicinal properties. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

Medicine | botany | plants | Health | Medicine | botany | plants | Health | 2011-10-31

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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The gene garden

Description

The spectacular variety of colour and growth form seen in our gardens is the result of the action of thousands of genes operating in pathways and networks. However, the basic principles of genetics are very simple and this lecture will explain how genes work, how they give rise to colour and form, and how they are re-assorted during reproduction to produce new and exciting plant varieties. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

plants | botany | DNA | genetics | botanic gardens | plants | botany | DNA | genetics | botanic gardens | 2011-10-17

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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2.611 Marine Power and Propulsion (MIT) 2.611 Marine Power and Propulsion (MIT)

Description

This course discusses the selection and evaluation of commercial and naval ship power and propulsion systems. It will cover the analysis of propulsors, prime mover thermodynamic cycles, propeller-engine matching, propeller selection, waterjet analysis, and reviews alternative propulsors. The course also investigates thermodynamic analyses of Rankine, Brayton, Diesel, and Combined cycles, reduction gears and integrated electric drive. Battery operated vehicles and fuel cells are also discussed. The term project requires analysis of alternatives in propulsion plant design for given physical, performance, and economic constraints. Graduate students complete different assignments and exams. This course discusses the selection and evaluation of commercial and naval ship power and propulsion systems. It will cover the analysis of propulsors, prime mover thermodynamic cycles, propeller-engine matching, propeller selection, waterjet analysis, and reviews alternative propulsors. The course also investigates thermodynamic analyses of Rankine, Brayton, Diesel, and Combined cycles, reduction gears and integrated electric drive. Battery operated vehicles and fuel cells are also discussed. The term project requires analysis of alternatives in propulsion plant design for given physical, performance, and economic constraints. Graduate students complete different assignments and exams.

Subjects

marine propulsion | marine propulsion | propellers | propellers | waterjets | waterjets | power plants | power plants | thermodynamics | thermodynamics | reversible cycles | reversible cycles | availability | availability | rankine cycle | rankine cycle | combustion | combustion | brayton cycle | brayton cycle | diesel cycle | diesel cycle | reduction gears | reduction gears | electric propulsors | electric propulsors | electric drive | electric drive | propulsion dynamics | propulsion dynamics | small underwater vehicles | small underwater vehicles

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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6.691 Seminar in Electric Power Systems (MIT) 6.691 Seminar in Electric Power Systems (MIT)

Description

This course comprises of a seminar on planning and operation of modern electric power systems. Content varies with current interests of instructor and class; emphasis on engineering aspects, but economic issues may be examined too. Core topics include: overview of power system structure and operation; representation of components, including transmission lines, transformers, generating plants, loads; power flow analysis, dynamics and control of multimachine systems, steady-state and transient stability, system protection; economic dispatch; mobile and isolated power systems; computation and simulation. This course comprises of a seminar on planning and operation of modern electric power systems. Content varies with current interests of instructor and class; emphasis on engineering aspects, but economic issues may be examined too. Core topics include: overview of power system structure and operation; representation of components, including transmission lines, transformers, generating plants, loads; power flow analysis, dynamics and control of multimachine systems, steady-state and transient stability, system protection; economic dispatch; mobile and isolated power systems; computation and simulation.

Subjects

Planning and operation of modern electric power systems | Planning and operation of modern electric power systems | engineering aspects | engineering aspects | power system structure and operation | power system structure and operation | representation of components | representation of components | transmission lines | transmission lines | transformers | transformers | generating plants | generating plants | loads | loads | power flow analysis | power flow analysis | dynamics and control of multimachine systems | dynamics and control of multimachine systems | steady-state and transient stability | steady-state and transient stability | system protection | system protection | economic dispatch | economic dispatch | mobil and isolated power systems | mobil and isolated power systems | computation and simulation | computation and simulation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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20.441J Biomaterials-Tissue Interactions (MIT) 20.441J Biomaterials-Tissue Interactions (MIT)

Description

This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological funct This course covers the principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. Mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Tissue and organ regeneration. Design of implants and prostheses based on control of biomaterials-tissue interactions. Comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Criteria for restoration of physiological funct

Subjects

20.441 | 20.441 | 2.79 | 2.79 | 3.96 | 3.96 | HST.522 | HST.522 | medical implants | medical implants | tissue engineering | tissue engineering | unit cell process | unit cell process | wound healing | wound healing | joint replacement | joint replacement | extracellular matrix | extracellular matrix | biocompatibility | biocompatibility

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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HST.723J Neural Coding and Perception of Sound (MIT) HST.723J Neural Coding and Perception of Sound (MIT)

Description

This course focuses on neural structures and mechanisms mediating the detection, localization and recognition of sounds. Discussions cover how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants. This course focuses on neural structures and mechanisms mediating the detection, localization and recognition of sounds. Discussions cover how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants.

Subjects

HST.723 | HST.723 | 9.285 | 9.285 | sound perception | sound perception | neural coding | neural coding | neural structures | neural structures | neural mechanisms | neural mechanisms | sound localization | sound localization | acoustic signals | acoustic signals | auditory neurons | auditory neurons | temporal coding | temporal coding | neural maps | neural maps | feature detectors | feature detectors | learning and plasticity | learning and plasticity | auditory masking | auditory masking | musical pitch | musical pitch | speech coding | speech coding | cochlear implants | cochlear implants | auditory system | auditory system | binaural interactions | binaural interactions | cochlear nucleus | cochlear nucleus | binaural hearing | binaural hearing | frequency selectivity | frequency selectivity | auditory cortex | auditory cortex | scene analysis | scene analysis | object formation | object formation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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3.032 Mechanical Behavior of Materials (MIT)

Description

Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, and fracture of materials including crystalline and amorphous metals, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. Integrated laboratories provide the opportunity to explore these concepts through hands-on experiments including instrumentation of pressure vessels, visualization of atomistic deformation in bubble rafts, nanoindentation, and uniaxial mechanical testing, as well as writing assignments to communicate th

Subjects

Basic concepts of solid mechanics and mechanical behavior of materials | stress-strain relationships | stress transformation | elasticity | plasticity and fracture. Case studies include materials selection for bicycle frames | stress shielding in biomedical implants; residual stresses in thin films; and ancient materials. Lab experiments and demonstrations give hands-on experience of the physical concepts at a variety of length scales. Use of facilities for measuring mechanical properties including standard mechanical tests | bubble raft models | atomic force microscopy and nanoindentation. | plasticity and fracture | Case studies | materials selection | bicycle frames | stress shielding in biomedical implants | residual stresses in thin films | ancient materials | standard mechanical tests | solid mechanics | mechanical behavior of materials

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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