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7.343 Biological Bases of Learning and Memory (MIT) 7.343 Biological Bases of Learning and Memory (MIT)

Description

How does the brain come to learn whether a stimulus is annoying, rewarding or neutral? How does remembering how to ride a bicycle differ from remembering scenes from a movie? In this course, students will explore the concept that learning and memory have a physical basis that can be observed as biochemical, physiological and/or morphological changes to neural tissue. Our goal will be to understand the strategies and techniques biologists use to search for the memory trace: the "holy grail" of modern neuroscience. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interact How does the brain come to learn whether a stimulus is annoying, rewarding or neutral? How does remembering how to ride a bicycle differ from remembering scenes from a movie? In this course, students will explore the concept that learning and memory have a physical basis that can be observed as biochemical, physiological and/or morphological changes to neural tissue. Our goal will be to understand the strategies and techniques biologists use to search for the memory trace: the "holy grail" of modern neuroscience. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interact

Subjects

learning | learning | memory | memory | neural tissue | neural tissue | neuronal connections | neuronal connections | synapse formation | synapse formation | synapse stabilization | synapse stabilization | synaptic transmission | synaptic transmission | synaptic plasticity | synaptic plasticity | neuromodulation | neuromodulation | experience-dependent circuit remodeling | experience-dependent circuit remodeling | neuroscience | neuroscience | pre- and post-synaptic mechanisms | pre- and post-synaptic mechanisms | neurotransmitter release | neurotransmitter release | activity-regulated genes | activity-regulated genes | hippocampus | hippocampus | long-term potentiation | long-term potentiation | long-term depression | long-term depression | cerebellar plasticity | cerebellar plasticity | Non-Associative | Non-Associative | Associative | Associative | cpg15 | cpg15 | experience-dependent synaptic plasticity | experience-dependent synaptic plasticity | perceptual learning | perceptual learning | observational learning | observational learning

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3.032 Mechanical Behavior of Materials (MIT) 3.032 Mechanical Behavior of Materials (MIT)

Description

Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, and fracture of materials including crystalline and amorphous metals, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. Integrated laboratories provide the opportunity to explore these concepts through hands-on experiments including instrumentation of pressure vessels, visualization of atomistic deformation in bubble rafts, nanoindentation, and uniaxial mechanical testing, as well as writing assignments to communicate th Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, and fracture of materials including crystalline and amorphous metals, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. Integrated laboratories provide the opportunity to explore these concepts through hands-on experiments including instrumentation of pressure vessels, visualization of atomistic deformation in bubble rafts, nanoindentation, and uniaxial mechanical testing, as well as writing assignments to communicate th

Subjects

Basic concepts of solid mechanics and mechanical behavior of materials | Basic concepts of solid mechanics and mechanical behavior of materials | stress-strain relationships | stress-strain relationships | stress transformation | stress transformation | elasticity | elasticity | plasticity and fracture. Case studies include materials selection for bicycle frames | plasticity and fracture. Case studies include materials selection for bicycle frames | stress shielding in biomedical implants; residual stresses in thin films; and ancient materials. Lab experiments and demonstrations give hands-on experience of the physical concepts at a variety of length scales. Use of facilities for measuring mechanical properties including standard mechanical tests | stress shielding in biomedical implants; residual stresses in thin films; and ancient materials. Lab experiments and demonstrations give hands-on experience of the physical concepts at a variety of length scales. Use of facilities for measuring mechanical properties including standard mechanical tests | bubble raft models | bubble raft models | atomic force microscopy and nanoindentation. | atomic force microscopy and nanoindentation. | plasticity and fracture | plasticity and fracture | Case studies | Case studies | materials selection | materials selection | bicycle frames | bicycle frames | stress shielding in biomedical implants | stress shielding in biomedical implants | residual stresses in thin films | residual stresses in thin films | ancient materials | ancient materials | standard mechanical tests | standard mechanical tests | solid mechanics | solid mechanics | mechanical behavior of materials | mechanical behavior of materials

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7.346 Synaptic Plasticity and Memory, from Molecules to Behavior (MIT) 7.346 Synaptic Plasticity and Memory, from Molecules to Behavior (MIT)

Description

In this course we will discover how innovative technologies combined with profound hypotheses have given rise to our current understanding of neuroscience. We will study both new and classical primary research papers with a focus on the plasticity between synapses in a brain structure called the hippocampus, which is believed to underlie the ability to create and retrieve certain classes of memories. We will discuss the basic electrical properties of neurons and how they fire. We will see how firing properties can change with experience, and we will study the biochemical basis of these changes. We will learn how molecular biology can be used to specifically change the biochemical properties of brain circuits, and we will see how these circuits form a representation of space giving rise to In this course we will discover how innovative technologies combined with profound hypotheses have given rise to our current understanding of neuroscience. We will study both new and classical primary research papers with a focus on the plasticity between synapses in a brain structure called the hippocampus, which is believed to underlie the ability to create and retrieve certain classes of memories. We will discuss the basic electrical properties of neurons and how they fire. We will see how firing properties can change with experience, and we will study the biochemical basis of these changes. We will learn how molecular biology can be used to specifically change the biochemical properties of brain circuits, and we will see how these circuits form a representation of space giving rise to

Subjects

synapse | synapse | memory | memory | neuroscience | neuroscience | plasticity | plasticity | hippocampus | hippocampus | LTP | LTP | molecular mechanism | molecular mechanism | Morris water maze | Morris water maze | place cells | place cells | NMDA | NMDA | synaptic tagging | synaptic tagging | long term depression | long term depression | cortex | cortex | synaptic plasticity | synaptic plasticity | neuronal circuits | neuronal circuits | specificity | specificity | CA1 | CA1 | grid cells | grid cells | schema | schema | fear memory | fear memory | biochemistry | biochemistry

License

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7.343 Biological Bases of Learning and Memory (MIT)

Description

How does the brain come to learn whether a stimulus is annoying, rewarding or neutral? How does remembering how to ride a bicycle differ from remembering scenes from a movie? In this course, students will explore the concept that learning and memory have a physical basis that can be observed as biochemical, physiological and/or morphological changes to neural tissue. Our goal will be to understand the strategies and techniques biologists use to search for the memory trace: the "holy grail" of modern neuroscience. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interact

Subjects

learning | memory | neural tissue | neuronal connections | synapse formation | synapse stabilization | synaptic transmission | synaptic plasticity | neuromodulation | experience-dependent circuit remodeling | neuroscience | pre- and post-synaptic mechanisms | neurotransmitter release | activity-regulated genes | hippocampus | long-term potentiation | long-term depression | cerebellar plasticity | Non-Associative | Associative | cpg15 | experience-dependent synaptic plasticity | perceptual learning | observational learning

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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9.14 Brain Structure and its Origins (MIT) 9.14 Brain Structure and its Origins (MIT)

Description

This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity. This course covers major CNS structures with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include basic patterns of connections in CNS, embryogenesis, PNS anatomy and development, process outgrowth and synaptogenesis, growth factors and cell survival, spinal and hindbrain anatomy, and development of regional specificity with an introduction to comparative anatomy and CNS evolution. A review of lab techniques (anatomy, tissue culture) is also covered as well as the trigeminal system, retinotectal system development, plasticity, regeneration, neocortex anatomy and development, the olfactory system, corpus striatum, brain transplants, the limbic system and hippocampal anatomy and plasticity.

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Development | Development

License

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9.373 Somatosensory and Motor Systems (MIT) 9.373 Somatosensory and Motor Systems (MIT)

Description

General principles of motor control in biological systems. Structure and function of sensory receptors. Muscle structure and reflex arcs. Spinal cord. Locomotion. Oculomotor control. Cerebellar structure and function. Motor thalamus. Basal ganglia. Somatosensory cortex: maps and neuronal properties. Cortical plasticity. Motor psychophysics and computational approaches to motor control, and motor planning. General principles of motor control in biological systems. Structure and function of sensory receptors. Muscle structure and reflex arcs. Spinal cord. Locomotion. Oculomotor control. Cerebellar structure and function. Motor thalamus. Basal ganglia. Somatosensory cortex: maps and neuronal properties. Cortical plasticity. Motor psychophysics and computational approaches to motor control, and motor planning.

Subjects

locomotion | locomotion | motor control | motor control | biological systems | biological systems | Structure | Structure | function | function | Muscle structure | Muscle structure | reflex | reflex | Spinal cord | Spinal cord | Oculomotor control | Oculomotor control | Cerebellar structure | Cerebellar structure | Motor thalamus | Motor thalamus | Basal ganglia | Basal ganglia | Somatosensory cortex | Somatosensory cortex | Cortical plasticity | Cortical plasticity | Motor psychophysics | Motor psychophysics | motor planning | motor planning | Locomotion | Locomotion

License

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9.013J Cellular and Molecular Neurobiology: The Brain and Cognitive Sciences III (MIT) 9.013J Cellular and Molecular Neurobiology: The Brain and Cognitive Sciences III (MIT)

Description

Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity. Includes lectures and exams, and involves presentation and discussion of primary literature. Focus on major concepts and recent advances in experimental neuroscience. Subject covers all major areas of cellular and molecular neurobiology including excitable cells and membranes, ion channels and receptors, synaptic transmission, cell type determination, axon guidance and targeting, neuronal cell biology, synapse formation and plasticity. Includes lectures and exams, and involves presentation and discussion of primary literature. Focus on major concepts and recent advances in experimental neuroscience.

Subjects

cellular | cellular | molecular neurobiology | molecular neurobiology | cells | cells | membranes | membranes | receptors | receptors | synaptic transmission | synaptic transmission | axon guidance | axon guidance | targeting | targeting | neuronal cell biology | neuronal cell biology | synapse formation | synapse formation | plasticity | plasticity | 9.013 | 9.013 | 7.68 | 7.68

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2.081J Plates and Shells (MIT) 2.081J Plates and Shells (MIT)

Description

This course explores the following topics: derivation of elastic and plastic stress-strain relations for plate and shell elements; the bending and buckling of rectangular plates; nonlinear geometric effects; post-buckling and ultimate strength of cold formed sections and typical stiffened panels used in naval architecture; the general theory of elastic shells and axisymmetric shells; buckling, crushing and bending strength of cylindrical shells with application to offshore structures; and the application to crashworthiness of vehicles and explosive and impact loading of structures. The class is taught during the first half of term. This course explores the following topics: derivation of elastic and plastic stress-strain relations for plate and shell elements; the bending and buckling of rectangular plates; nonlinear geometric effects; post-buckling and ultimate strength of cold formed sections and typical stiffened panels used in naval architecture; the general theory of elastic shells and axisymmetric shells; buckling, crushing and bending strength of cylindrical shells with application to offshore structures; and the application to crashworthiness of vehicles and explosive and impact loading of structures. The class is taught during the first half of term.

Subjects

plates | plates | shells | shells | engineering strain | engineering strain | strain measure | strain measure | bending moment | bending moment | structural plasticity | structural plasticity | membrane energy | membrane energy | green-lagrangian strain | green-lagrangian strain | bending theory of plates | bending theory of plates | buckling theory of plates | buckling theory of plates | raleigh-ritz quotient | raleigh-ritz quotient | local buckling | local buckling | plastic buckling | plastic buckling | cylindrical shells | cylindrical shells | axial load | axial load | lateral pressure | lateral pressure | hydrostatic pressure | hydrostatic pressure | torsion | torsion | bending boundary conditions | bending boundary conditions | strain-displacement | strain-displacement | 2.081 | 2.081 | 16.230 | 16.230

License

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9.03 Neural Basis of Learning and Memory (MIT) 9.03 Neural Basis of Learning and Memory (MIT)

Description

This course covers topics in mammalian learning and memory including cellular mechanisms of neural plasticity, electrophysiology, and behavior. In lectures and discussion of papers, emphasis is placed on human and animal models of hippocampal mechanisms and function. This course covers topics in mammalian learning and memory including cellular mechanisms of neural plasticity, electrophysiology, and behavior. In lectures and discussion of papers, emphasis is placed on human and animal models of hippocampal mechanisms and function.

Subjects

learning | learning | memory | memory | neural plasticity | neural plasticity | electrophysiology | electrophysiology | hippocampus | hippocampus | synapse | synapse | aplysia | aplysia | drosophlia | drosophlia | NMDA | NMDA | semantic memory | semantic memory | working memory | working memory | short-term memory | short-term memory | alzheimer's disease | alzheimer's disease

License

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13.811 Advanced Structural Dynamics and Acoustics (MIT) 13.811 Advanced Structural Dynamics and Acoustics (MIT)

Description

This course begins with the foundations of 3D elasticity, fluid and elastic wave equations, elastic and plastic waves in rods and beams, waves in plates, and dynamics and acoustics of cylindrical shells. The course considers acoustic fluids effects such as radiation and scattering by submerged plates and shells, and interaction between structural elements. Finally, it covers the response of plates and shells to high-intensity loads, dynamic plasticity and fracture, and structural damage caused by implosive and impact loads.Technical RequirementsMATLAB® software is required to run the .m files found on this course site. File decompression software, such as Winzip® or StuffIt®, is required to open the .zip files found on this course site. This course begins with the foundations of 3D elasticity, fluid and elastic wave equations, elastic and plastic waves in rods and beams, waves in plates, and dynamics and acoustics of cylindrical shells. The course considers acoustic fluids effects such as radiation and scattering by submerged plates and shells, and interaction between structural elements. Finally, it covers the response of plates and shells to high-intensity loads, dynamic plasticity and fracture, and structural damage caused by implosive and impact loads.Technical RequirementsMATLAB® software is required to run the .m files found on this course site. File decompression software, such as Winzip® or StuffIt®, is required to open the .zip files found on this course site.

Subjects

3D elasticity | 3D elasticity | wave equations | wave equations | elastic wave | elastic wave | plastic wave | plastic wave | plates | plates | shells | shells | cylindrical shells | cylindrical shells | submerged plates and shells | submerged plates and shells | high-intensity load | high-intensity load | dynamic plasticity | dynamic plasticity | fracture | fracture | implosive load | implosive load | impact load | impact load | radiation | radiation | harmonics | harmonics | scattering | scattering | spheres | spheres | waves | waves | cylinders | cylinders | 2.067 | 2.067

License

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3.22 Mechanical Properties of Materials (MIT) 3.22 Mechanical Properties of Materials (MIT)

Description

Phenomenology of mechanical behavior of materials at the macroscopic level. Relationship of mechanical behavior to material structure and mechanisms of deformation and failure. Topics include: elasticity, viscoelasticity, plasticity, creep, fracture, and fatigue. Case studies and examples drawn from structural and functional applications that include a variety of material classes: metals, ceramics, polymers, thin films, composites, and cellular materials. Phenomenology of mechanical behavior of materials at the macroscopic level. Relationship of mechanical behavior to material structure and mechanisms of deformation and failure. Topics include: elasticity, viscoelasticity, plasticity, creep, fracture, and fatigue. Case studies and examples drawn from structural and functional applications that include a variety of material classes: metals, ceramics, polymers, thin films, composites, and cellular materials.

Subjects

Phenomenology | Phenomenology | mechanical behavior | mechanical behavior | material structure | material structure | deformation | deformation | failure | failure | elasticity | elasticity | viscoelasticity | viscoelasticity | plasticity | plasticity | creep | creep | fracture | fracture

License

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HST.723 Neural Coding and Perception of Sound (MIT) HST.723 Neural Coding and Perception of Sound (MIT)

Description

Neural structures and mechanisms mediating the detection, localization and recognition of sounds. We will discuss how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants. Neural structures and mechanisms mediating the detection, localization and recognition of sounds. We will discuss how acoustic signals are coded by auditory neurons, the impact of these codes on behavioral performance, and the circuitry and cellular mechanisms underlying signal transformations. Topics include temporal coding, neural maps and feature detectors, learning and plasticity, and feedback control. General principles are conveyed by theme discussions of auditory masking, sound localization, musical pitch, speech coding, and cochlear implants.

Subjects

hearing | hearing | neural structures | neural structures | auditory masking | auditory masking | acoustics | acoustics | signal transformations | signal transformations | temporal coding | temporal coding | neural maps | neural maps | feature detectors | feature detectors | learning | learning | plasticity | plasticity | feedback control | feedback control | sound localization | sound localization | musical pitch | musical pitch | speech coding | speech coding | cochlear implants | cochlear implants

License

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9.03 Neural Basis of Learning and Memory (MIT) 9.03 Neural Basis of Learning and Memory (MIT)

Description

Topics in mammalian learning and memory including cellular mechanisms of neural plasticity, electrophysiology, and behavior. Emphasis on human and animal models of hippocampal mechanisms and function. Lectures and discussion of papers. An additional project is required for graduate credit. This course is offered alternate years. Topics in mammalian learning and memory including cellular mechanisms of neural plasticity, electrophysiology, and behavior. Emphasis on human and animal models of hippocampal mechanisms and function. Lectures and discussion of papers. An additional project is required for graduate credit. This course is offered alternate years.

Subjects

learning | learning | memory | memory | neural plasticity | neural plasticity | electrophysiology | electrophysiology | hippocampus | hippocampus

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Development of the Mammalian Brain (MIT) Development of the Mammalian Brain (MIT)

Description

Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play Lectures plus guided readings and discussion with project reports, covering major CNS structures, with emphasis on systems being used as models for experimental studies of development and plasticity. Topics include: basic patterns of connections in CNS; review of lab techniques (anatomy, tissue culture); embryogenesis; PNS anatomy and development; process outgrowth and synaptogenesis; growth factors and cell survival; spinal and hindbrain anatomy; development of regional specificity with introduction to comparative anatomy and CNS evolution; trigeminal system; retinotectal system development, plasticity, regeneration; neocortex anatomy and development; olfactory system; corpus striatum; brain transplants; limbic system and hippocampal anatomy and plasticity.Technical RequirementsMedia play

Subjects

CNS structures | CNS structures | development | development | plasticity | plasticity | anatomy | anatomy | tissue culture | tissue culture | embryogenesis | embryogenesis | PNS anatomy and development | PNS anatomy and development | process outgrowth | process outgrowth | synaptogenesis | synaptogenesis | growth factors | growth factors | cell survival | cell survival | spinal and hindbrain anatomy | spinal and hindbrain anatomy | comparative anatomy | comparative anatomy | CNS evolution | CNS evolution | trigeminal system | trigeminal system | retinotectal system | retinotectal system | regeneration | regeneration | neocortex anatomy | neocortex anatomy | olfactory system | olfactory system | corpus striatum | corpus striatum | brain transplants | brain transplants | limbic system | limbic system | Mammals -- Physiology | Mammals -- Physiology

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1.322 Soil Behavior (MIT) 1.322 Soil Behavior (MIT)

Description

This class presents a detailed study of soil properties with emphasis on interpretation of field and laboratory test data and their use in soft-ground construction engineering. Topics to be covered include: consolidation and secondary compression; basic strength principles; stress-strain strength behavior of clays, emphasizing effects of sample disturbance, anisotropy, and strain rate; strength and compression of granular soils; and engineering properties of compacted soils. Some knowledge of field and laboratory testing is assumed for all students. This class presents a detailed study of soil properties with emphasis on interpretation of field and laboratory test data and their use in soft-ground construction engineering. Topics to be covered include: consolidation and secondary compression; basic strength principles; stress-strain strength behavior of clays, emphasizing effects of sample disturbance, anisotropy, and strain rate; strength and compression of granular soils; and engineering properties of compacted soils. Some knowledge of field and laboratory testing is assumed for all students.

Subjects

soil | soil | soil composition | soil composition | clay | clay | interparticle forces | interparticle forces | soil strength | soil strength | laddite | laddite | Hvorslev parameters | Hvorslev parameters | plasticity | plasticity | stress history | stress history | consol | consol | conductivity | conductivity | compression | compression | consolidation | consolidation | problem soils | problem soils | sands | sands

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1.054 Mechanics and Design of Concrete Structures (MIT) 1.054 Mechanics and Design of Concrete Structures (MIT)

Description

The main objective of 1.054/1.541 is to provide students with a rational basis of the design of reinforced concrete members and structures through advanced understanding of material and structural behavior. This course is offered to undergraduate (1.054) and graduate students (1.541). Topics covered include: Strength and Deformation of Concrete under Various States of Stress; Failure Criteria; Concrete Plasticity; Fracture Mechanics Concepts; Fundamental Behavior of Reinforced Concrete Structural Systems and their Members; Basis for Design and Code Constraints; High-performance Concrete Materials and their use in Innovative Design Solutions; Slabs: Yield Line Theory; Behavior Models and Nonlinear Analysis; and Complex Systems: Bridge Structures, Concrete Shells, and Containments. Professor The main objective of 1.054/1.541 is to provide students with a rational basis of the design of reinforced concrete members and structures through advanced understanding of material and structural behavior. This course is offered to undergraduate (1.054) and graduate students (1.541). Topics covered include: Strength and Deformation of Concrete under Various States of Stress; Failure Criteria; Concrete Plasticity; Fracture Mechanics Concepts; Fundamental Behavior of Reinforced Concrete Structural Systems and their Members; Basis for Design and Code Constraints; High-performance Concrete Materials and their use in Innovative Design Solutions; Slabs: Yield Line Theory; Behavior Models and Nonlinear Analysis; and Complex Systems: Bridge Structures, Concrete Shells, and Containments. Professor

Subjects

concrete structures | concrete structures | mechanics | mechanics | design | design | strength | strength | deformation | deformation | stress | stress | strain | strain | failure criteria | failure criteria | concrete plasticity | concrete plasticity | fracture mechanics | fracture mechanics | reinforced concrete | reinforced concrete | code constraints | code constraints | high-performance materials | high-performance materials | slabs | slabs | yield line theory | yield line theory | behavior models | behavior models | nonlinear analysis | nonlinear analysis | bridge structures | bridge structures | concrete shells | concrete shells | containments | containments

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1.033 Mechanics of Material Systems: An Energy Approach (MIT) 1.033 Mechanics of Material Systems: An Energy Approach (MIT)

Description

1.033 provides an introduction to continuum mechanics and material modeling of engineering materials based on first energy principles: deformation and strain; momentum balance, stress and stress states; elasticity and elasticity bounds; plasticity and yield design. The overarching theme is a unified mechanistic language using thermodynamics, which allows understanding, modeling and design of a large range of engineering materials. This course is offered both to undergraduate (1.033) and graduate (1.57) students. 1.033 provides an introduction to continuum mechanics and material modeling of engineering materials based on first energy principles: deformation and strain; momentum balance, stress and stress states; elasticity and elasticity bounds; plasticity and yield design. The overarching theme is a unified mechanistic language using thermodynamics, which allows understanding, modeling and design of a large range of engineering materials. This course is offered both to undergraduate (1.033) and graduate (1.57) students.

Subjects

continuum mechanics | continuum mechanics | material modeling | material modeling | engineering materials | engineering materials | energy principles: deformation and strain | energy principles: deformation and strain | momentum balance | momentum balance | stress | stress | stress states | stress states | elasticity and elasticity bounds | elasticity and elasticity bounds | plasticity | plasticity | yield design | yield design | first energy principles | first energy principles | deformation | deformation | strain | strain | elasticity bounds | elasticity bounds | unified mechanistic language | unified mechanistic language | thermodynamics | thermodynamics | engineering structures | engineering structures | unified framework | unified framework | irreversible processes | irreversible processes | structural engineering | structural engineering | soil mechanics | soil mechanics | mechanical engineering | mechanical engineering | materials science | materials science | solids | solids | durability mechanics | durability mechanics

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2.081J Plates and Shells (MIT) 2.081J Plates and Shells (MIT)

Description

This course explores the following topics: derivation of elastic and plastic stress-strain relations for plate and shell elements; the bending and buckling of rectangular plates; nonlinear geometric effects; post-buckling and ultimate strength of cold formed sections and typical stiffened panels used in naval architecture; the general theory of elastic shells and axisymmetric shells; buckling, crushing and bending strength of cylindrical shells with application to offshore structures; and the application to crashworthiness of vehicles and explosive and impact loading of structures. The class is taught during the first half of term. This course explores the following topics: derivation of elastic and plastic stress-strain relations for plate and shell elements; the bending and buckling of rectangular plates; nonlinear geometric effects; post-buckling and ultimate strength of cold formed sections and typical stiffened panels used in naval architecture; the general theory of elastic shells and axisymmetric shells; buckling, crushing and bending strength of cylindrical shells with application to offshore structures; and the application to crashworthiness of vehicles and explosive and impact loading of structures. The class is taught during the first half of term.

Subjects

plates | plates | shells | shells | engineering strain | engineering strain | strain measure | strain measure | bending moment | bending moment | structural plasticity | structural plasticity | membrane energy | membrane energy | green-lagrangian strain | green-lagrangian strain | bending theory of plates | bending theory of plates | buckling theory of plates | buckling theory of plates | raleigh-ritz quotient | raleigh-ritz quotient | local buckling | local buckling | plastic buckling | plastic buckling | cylindrical shells | cylindrical shells | axial load | axial load | lateral pressure | lateral pressure | hydrostatic pressure | hydrostatic pressure | torsion | torsion | bending boundary conditions | bending boundary conditions | strain-displacement | strain-displacement | 2.081 | 2.081 | 16.230 | 16.230

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2.067 Advanced Structural Dynamics and Acoustics (13.811) (MIT) 2.067 Advanced Structural Dynamics and Acoustics (13.811) (MIT)

Description

This course begins with the foundations of 3D elasticity, fluid and elastic wave equations, elastic and plastic waves in rods and beams, waves in plates, and dynamics and acoustics of cylindrical shells. The course considers acoustic fluids effects such as radiation and scattering by submerged plates and shells, and interaction between structural elements. Finally, it covers the response of plates and shells to high-intensity loads, dynamic plasticity and fracture, and structural damage caused by implosive and impact loads. This course was originally offered in Course 13 (Department of Ocean Engineering) as 13.811. In 2005, ocean engineering subjects became part of Course 2 (Department of Mechanical Engineering), and this course was renumbered 2.067. This course begins with the foundations of 3D elasticity, fluid and elastic wave equations, elastic and plastic waves in rods and beams, waves in plates, and dynamics and acoustics of cylindrical shells. The course considers acoustic fluids effects such as radiation and scattering by submerged plates and shells, and interaction between structural elements. Finally, it covers the response of plates and shells to high-intensity loads, dynamic plasticity and fracture, and structural damage caused by implosive and impact loads. This course was originally offered in Course 13 (Department of Ocean Engineering) as 13.811. In 2005, ocean engineering subjects became part of Course 2 (Department of Mechanical Engineering), and this course was renumbered 2.067.

Subjects

3D elasticity | 3D elasticity | wave equations | wave equations | elastic wave | elastic wave | plastic wave | plastic wave | plates | plates | shells | shells | cylindrical shells | cylindrical shells | submerged plates and shells | submerged plates and shells | high-intensity load | high-intensity load | dynamic plasticity | dynamic plasticity | fracture | fracture | implosive load | implosive load | impact load | impact load | radiation | radiation | harmonics | harmonics | scattering | scattering | spheres | spheres | waves | waves | cylinders | cylinders

License

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2.002 Mechanics and Materials II (MIT) 2.002 Mechanics and Materials II (MIT)

Description

This course provides Mechanical Engineering students with an awareness of various responses exhibited by solid engineering materials when subjected to mechanical and thermal loadings; an introduction to the physical mechanisms associated with design-limiting behavior of engineering materials, especially stiffness, strength, toughness, and durability; an understanding of basic mechanical properties of engineering materials, testing procedures used to quantify these properties, and ways in which these properties characterize material response; quantitative skills to deal with materials-limiting problems in engineering design; and a basis for materials selection in mechanical design. This course provides Mechanical Engineering students with an awareness of various responses exhibited by solid engineering materials when subjected to mechanical and thermal loadings; an introduction to the physical mechanisms associated with design-limiting behavior of engineering materials, especially stiffness, strength, toughness, and durability; an understanding of basic mechanical properties of engineering materials, testing procedures used to quantify these properties, and ways in which these properties characterize material response; quantitative skills to deal with materials-limiting problems in engineering design; and a basis for materials selection in mechanical design.

Subjects

beam bending | beam bending | buckling | buckling | vibration | vibration | polymers | polymers | viscoelasticity | viscoelasticity | strength | strength | ductility | ductility | stress | stress | stress concentration | stress concentration | sheet bending | sheet bending | heat treatment | heat treatment | fracture | fracture | plasticity | plasticity | creep | creep | fatigue | fatigue | solid materials | solid materials | mechanical loading | mechanical loading | thermal loading | thermal loading | design-limiting behavior | design-limiting behavior | stiffness | stiffness | toughness | toughness | durability | durability | engineering materials | engineering materials | materials-limiting problem | materials-limiting problem | materials selection | materials selection

License

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3.22 Mechanical Behavior of Materials (MIT) 3.22 Mechanical Behavior of Materials (MIT)

Description

Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, fracture and fatigue of materials including crystalline and amorphous metals, semiconductors, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. We will cover special topics in mechanical behavior for material systems of your choice, with reference to current research and publications. Here we will learn about the mechanical behavior of structures and materials, from the continuum description of properties to the atomistic and molecular mechanisms that confer those properties to all materials. We will cover elastic and plastic deformation, creep, fracture and fatigue of materials including crystalline and amorphous metals, semiconductors, ceramics, and (bio)polymers, and will focus on the design and processing of materials from the atomic to the macroscale to achieve desired mechanical behavior. We will cover special topics in mechanical behavior for material systems of your choice, with reference to current research and publications.

Subjects

Phenomenology | Phenomenology | mechanical behavior | mechanical behavior | material structure | material structure | deformation | deformation | failure | failure | elasticity | elasticity | viscoelasticity | viscoelasticity | plasticity | plasticity | creep | creep | fracture | fracture | fatigue | fatigue | metals | metals | semiconductors | semiconductors | ceramics | ceramics | polymers | polymers | microstructure | microstructure | composition | composition | semiconductor diodes | semiconductor diodes | thin films | thin films | carbon nanotubes | carbon nanotubes | battery materials | battery materials | superelastic alloys | superelastic alloys | defect nucleation | defect nucleation | student projects | student projects | viral capsides | viral capsides

License

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3.225 Electronic and Mechanical Properties of Materials (MIT) 3.225 Electronic and Mechanical Properties of Materials (MIT)

Description

This course covers the fundamental concepts that determine the electrical, optical, magnetic and mechanical properties of metals, semiconductors, ceramics and polymers. The roles of bonding, structure (crystalline, defect, energy band and microstructure) and composition in influencing and controlling physical properties are discussed. Also included are case studies drawn from a variety of applications: semiconductor diodes and optical detectors, sensors, thin films, biomaterials, composites and cellular materials, and others. This course covers the fundamental concepts that determine the electrical, optical, magnetic and mechanical properties of metals, semiconductors, ceramics and polymers. The roles of bonding, structure (crystalline, defect, energy band and microstructure) and composition in influencing and controlling physical properties are discussed. Also included are case studies drawn from a variety of applications: semiconductor diodes and optical detectors, sensors, thin films, biomaterials, composites and cellular materials, and others.

Subjects

metals | metals | semiconductors | semiconductors | ceramics | ceramics | polymers | polymers | bonding | bonding | structure | structure | energy band | energy band | microstructure | microstructure | composition | composition | semiconductor diodes | semiconductor diodes | optical detectors | optical detectors | sensors | sensors | thin films | thin films | biomaterials | biomaterials | cellular materials | cellular materials | magnetism | magnetism | polarity | polarity | viscoelasticity | viscoelasticity | plasticity | plasticity | fracture | fracture | materials selection | materials selection

License

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7.340 Learning and Memory: Activity-Controlled Gene Expression in the Nervous System (MIT) 7.340 Learning and Memory: Activity-Controlled Gene Expression in the Nervous System (MIT)

Description

The mammalian brain easily outperforms any computer. It adapts and changes constantly. Most importantly, the brain enables us to continuously learn and remember. What are the molecular mechanisms that lead to learning and memory? What are the cellular roles that activity-regulated gene products play to implement changes in the brain?How do nerve cells, their connections (synapses), and brain circuits change over time to store information? We will discuss the molecular mechanisms of neuronal plasticity at the synaptic, cellular and circuit levels, especiallysynapse formation,synaptic growth and stabilization,synaptic transmission,axonal and dendritic outgrowth, andcircuit formationWe will learn about the roles of some activity-regulated genes as well as the tools and techniques employed in The mammalian brain easily outperforms any computer. It adapts and changes constantly. Most importantly, the brain enables us to continuously learn and remember. What are the molecular mechanisms that lead to learning and memory? What are the cellular roles that activity-regulated gene products play to implement changes in the brain?How do nerve cells, their connections (synapses), and brain circuits change over time to store information? We will discuss the molecular mechanisms of neuronal plasticity at the synaptic, cellular and circuit levels, especiallysynapse formation,synaptic growth and stabilization,synaptic transmission,axonal and dendritic outgrowth, andcircuit formationWe will learn about the roles of some activity-regulated genes as well as the tools and techniques employed in

Subjects

learning | learning | memory | memory | genes | genes | genetic expression | genetic expression | nervous system | nervous system | neuroscience | neuroscience | neuronal plasticity | neuronal plasticity | synapse formation | synapse formation | synaptic growth | synaptic growth | synaptic stabilization | synaptic stabilization | synaptic transmission | synaptic transmission | axonal outgrowth | axonal outgrowth | dendritic outgrowth | dendritic outgrowth | neural circuit formation | neural circuit formation

License

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7.349 From Molecules to Behavior: Synaptic Neurophysiology (MIT) 7.349 From Molecules to Behavior: Synaptic Neurophysiology (MIT)

Description

Like transistors in a computer, synapses perform complex computations and connect the brain's non-linear processing elements (neurons) into a functional circuit. Understanding the role of synapses in neuronal computation is essential to understanding how the brain works. In this course students will be introduced to cutting-edge research in the field of synaptic neurophysiology. The course will cover such topics as synapse formation, synaptic function, synaptic plasticity, the roles of synapses in higher cognitive processes and how synaptic dysfunction can lead to disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn ab Like transistors in a computer, synapses perform complex computations and connect the brain's non-linear processing elements (neurons) into a functional circuit. Understanding the role of synapses in neuronal computation is essential to understanding how the brain works. In this course students will be introduced to cutting-edge research in the field of synaptic neurophysiology. The course will cover such topics as synapse formation, synaptic function, synaptic plasticity, the roles of synapses in higher cognitive processes and how synaptic dysfunction can lead to disease. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn ab

Subjects

synaptic neurophysiology | synaptic neurophysiology | neuron | neuron | synaptic fusion | synaptic fusion | synaptic release | synaptic release | synaptic plasticity | synaptic plasticity | neuronal circuits | neuronal circuits

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9.S915 Developmental Cognitive Neuroscience (MIT) 9.S915 Developmental Cognitive Neuroscience (MIT)

Description

This course uses neuroscience methods to study the cognitive development of human infants and children. Case studies draw from research on face recognition, language, executive function, representations of objects, number and theory of mind. This course uses neuroscience methods to study the cognitive development of human infants and children. Case studies draw from research on face recognition, language, executive function, representations of objects, number and theory of mind.

Subjects

development | development | cognition | cognition | theory of mind | theory of mind | neuroscience | neuroscience | childhood | childhood | learning | learning | plasticity | plasticity | executive function | executive function | perception | perception

License

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