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7.27 Principles of Human Disease (MIT) 7.27 Principles of Human Disease (MIT)

Description

This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies. This course covers current understanding of, and modern approaches to human disease, emphasizing the molecular and cellular basis of both genetic disease and cancer. Topics include: The Genetics of Simple and Complex Traits; Karyotypic Analysis and Positional Cloning; Genetic Diagnosis; The Roles of Oncogenes and Tumor Suppressors in Tumor Initiation, Progression, and Treatment; The Interaction between Genetics and Environment; Animal Models of Human Disease; Cancer; and Conventional and Gene Therapy Treatment Strategies.

Subjects

human disease | human disease | molecular basis of genetic disease | molecular basis of genetic disease | molecular basis of cancer | molecular basis of cancer | cellular basis of genetic disease | cellular basis of genetic disease | cellular basis of cancer | cellular basis of cancer | genetics of simple and complex traits | genetics of simple and complex traits | karyotypic analysis | karyotypic analysis | positional cloning | positional cloning | genetic diagnosis | genetic diagnosis | roles of oncogenes | roles of oncogenes | tumor suppressors | tumor suppressors | tumor initiation | tumor initiation | tumor progression | tumor progression | tumor treatment | tumor treatment | interaction between genetics and environment | interaction between genetics and environment | animal models of human disease | animal models of human disease | cancer | cancer | conventional treatment strategies | conventional treatment strategies | gene therapy treatment strategies | gene therapy treatment strategies

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Construction of Northbank's hull continues

Description

Construction work continues on the hull of the cargo ship ?Northbank? at the shipyard of William Doxford & Sons, Sunderland, 27 September 1956 (TWAM ref. DS.DOX/4/PH/1/819/1/4) This album documents the construction of the cargo ship ?Northbank? by the famous shipbuilding firm William Doxford & Sons at its Pallion yard, Sunderland. Most of these images are progress photographs, taken a week apart between September 1956 and January 1957 from approximately the same spot. They give a fascinating insight into how the vessel was built. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.

Subjects

williamdoxfordandsonsltd | pallion | sunderland | shipbuilding | shipyard | industry | industrial | hull | construction | northbank | ship | vessel | riverwear | wearside | cargoship | supportblocks | northeastengland | builtinsunderland | constructionwork | development | structure | frame | platform | components | archives | industrialheritage | blackandwhitephotograph | digitalimage | fascinating | impressive | interesting | unusual | unitedkingdom | transportation | maritimeheritage | shipbuildingheritage | abstract | 27september1956 | pallionyard | progress | progression | progressionphotographs | river | bank | land | blur | grain | mark | sky | daylight | debris | reflection | buildings | wall | roof | label | letters | digit | ladder | hose | sections | pile | parts | production | northbankshull

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CMS.608 Game Design (MIT) CMS.608 Game Design (MIT)

Description

Includes audio/video content: AV selected lectures. This course provides practical instruction in the design and analysis of non-digital games. Students cover the texts, tools, references and historical context to analyze and compare game designs across a variety of genres, including sports, game shows, games of chance, card games, schoolyard games, board games, and role–playing games. In teams, students design, develop, and thoroughly test their original games to understand the interaction and evolution of game rules. Students taking the graduate version complete additional assignments. Includes audio/video content: AV selected lectures. This course provides practical instruction in the design and analysis of non-digital games. Students cover the texts, tools, references and historical context to analyze and compare game designs across a variety of genres, including sports, game shows, games of chance, card games, schoolyard games, board games, and role–playing games. In teams, students design, develop, and thoroughly test their original games to understand the interaction and evolution of game rules. Students taking the graduate version complete additional assignments.

Subjects

games | games | puzzles | puzzles | narrative | narrative | playtestin | playtestin | chance | chance | competition | competition | strategy | strategy | rules | rules | gambling | gambling | emergence | emergence | progression | progression | randomness | randomness | cooperation | cooperation | iterative design | iterative design | prototyping | prototyping | game mechanics | game mechanics | aesthetics | aesthetics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Lecture 25: Fiction and Stories in Games Lecture 25: Fiction and Stories in Games

Description

Description: Many games incorporate story elements, to drive the plot, set the scene, create engaging characters, etc. Some even use player actions to build an open-ended adventure. Clara Fernandez-Vara talks about how and why to use stories in games. Instructors/speakers: Philip Tan, Jason Begy, Clara Fernandez-Vara (Singapore-MIT GAMBIT Game Lab)Keywords: narrative, environmental storytelling, roleplaying, emergence, storybuilding, non-digital games, digital games, game state, stories, fiction, setting, characters, theme, progression, improvisation, micronarrative, premise, game event, game mechanic, ethics, board games, card gamesTranscript: PDFSubtitles: SRTAudio - download: Internet Archive (MP3)Audio - download: iTunes U (MP3)(CC BY-NC-SA) Description: Many games incorporate story elements, to drive the plot, set the scene, create engaging characters, etc. Some even use player actions to build an open-ended adventure. Clara Fernandez-Vara talks about how and why to use stories in games. Instructors/speakers: Philip Tan, Jason Begy, Clara Fernandez-Vara (Singapore-MIT GAMBIT Game Lab)Keywords: narrative, environmental storytelling, roleplaying, emergence, storybuilding, non-digital games, digital games, game state, stories, fiction, setting, characters, theme, progression, improvisation, micronarrative, premise, game event, game mechanic, ethics, board games, card gamesTranscript: PDFSubtitles: SRTAudio - download: Internet Archive (MP3)Audio - download: iTunes U (MP3)(CC BY-NC-SA)

Subjects

narrative | narrative | environmental storytelling | environmental storytelling | roleplaying | roleplaying | emergence | emergence | storybuilding | storybuilding | non-digital games | non-digital games | digital games | digital games | game state | game state | stories | stories | fiction | fiction | setting | setting | characters | characters | theme | theme | progression | progression | improvisation | improvisation | micronarrative | micronarrative | premise | premise | game event | game event | game mechanic | game mechanic | ethics | ethics | board games | board games | card games | card games

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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CMS.608 Game Design (MIT) CMS.608 Game Design (MIT)

Description

An historical examination and analysis of the evolution and development of games and game mechanics. Topics include a large breadth of genres and types of games, including sports, game shows, games of chance, schoolyard games, board games, roleplaying games, and digital games. Students submit essays documenting research and analysis of a variety of traditional and eclectic games. Project teams required to design, develop, and thoroughly test their original games. An historical examination and analysis of the evolution and development of games and game mechanics. Topics include a large breadth of genres and types of games, including sports, game shows, games of chance, schoolyard games, board games, roleplaying games, and digital games. Students submit essays documenting research and analysis of a variety of traditional and eclectic games. Project teams required to design, develop, and thoroughly test their original games.

Subjects

a | a | games | games | narrative | narrative | playtesting | playtesting | student work | student work | student notes | student notes | chance | chance | competition | competition | information | information | probability | probability | strategy | strategy | theory | theory | symbolism | symbolism | rules | rules | gambling | gambling | emergence | emergence | progression | progression | randomness | randomness | cooperation | cooperation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.342 Pluripotent Stem Cells and Genome Engineering for Modeling Human Diseases (MIT) 7.342 Pluripotent Stem Cells and Genome Engineering for Modeling Human Diseases (MIT)

Description

One of the major priorities in biomedical research is understanding the molecular events that establish the complex processes involved in human development and the relationships of these processes to human disease and disease progression. In this class, we will explore stem cell biology and the way in which it has developed and shaped our ability to study complex human disease. We will introduce the field of stem cell biology and genome engineering through critical reading of both the classical and newest primary research literature. In addition, this course will discuss specific disease model systems and their benefits / limitations for understanding the disease and treating human patients. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT One of the major priorities in biomedical research is understanding the molecular events that establish the complex processes involved in human development and the relationships of these processes to human disease and disease progression. In this class, we will explore stem cell biology and the way in which it has developed and shaped our ability to study complex human disease. We will introduce the field of stem cell biology and genome engineering through critical reading of both the classical and newest primary research literature. In addition, this course will discuss specific disease model systems and their benefits / limitations for understanding the disease and treating human patients. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT

Subjects

stem cells | stem cells | genome engineering | genome engineering | pluripotency | pluripotency | disease progression | disease progression | embryonic stem cells | embryonic stem cells | induced pluripotent stem cells | induced pluripotent stem cells | transgenic animals | transgenic animals | regenerative medicine | regenerative medicine | CRISPR/cas9 | CRISPR/cas9 | Nuclear Transfer | Nuclear Transfer | Cellular Reprogramming | Cellular Reprogramming

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Arithmetic and geometric progressions

Description

Arithmetic and geometric progressions are particular types of sequences of numbers which occur frequently in business calculations. This leaflet explains these terms, and shows how the sums of these sequences can be found.

Subjects

arithmetic progression | geometric progression | Computer science | I100

License

Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-nd/2.0/uk/ http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

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Dredging in progress at Folly End, Sunderland Dredging in progress at Folly End, Sunderland

Description

Subjects

portofsunderland | portofsunderland | sunderland | sunderland | riverwear | riverwear | historic | historic | follyend | follyend | dredger | dredger | dredging | dredging | boats | boats | vessels | vessels | wearmouthbridge | wearmouthbridge | bridges | bridges | rivers | rivers | wearside | wearside | quays | quays | ferry | ferry | wfvint | wfvint | monkwearmouth | monkwearmouth | blackandwhitephotograph | blackandwhitephotograph | digitalimage | digitalimage | abstract | abstract | archives | archives | industry | industry | industrialheritage | industrialheritage | maritimeheritage | maritimeheritage | shipbuildingheritage | shipbuildingheritage | northeastofengland | northeastofengland | unitedkingdom | unitedkingdom | interesting | interesting | unusual | unusual | fascinating | fascinating | impressive | impressive | progression | progression | progress | progress | june1950 | june1950 | follyendremovalscheme | follyendremovalscheme | navigation | navigation | river | river | ferryboat | ferryboat | portauthority | portauthority | 1717 | 1717 | actofparliament | actofparliament | riverwearcommissioners | riverwearcommissioners | management | management | transportation | transportation | structure | structure | construction | construction | harbour | harbour | port | port | piers | piers | docks | docks | coaltrade | coaltrade | alliedindustries | alliedindustries | marineengineering | marineengineering | shiprepairing | shiprepairing | deck | deck | rail | rail | chimney | chimney | smoke | smoke | sky | sky | water | water | land | land | bank | bank | cabin | cabin | bridge | bridge | crane | crane | buildings | buildings | wall | wall | roof | roof | window | window | frame | frame | glass | glass | mast | mast | soil | soil | pile | pile | cog | cog

License

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Construction of Northbank's hull continues

Description

Subjects

williamdoxfordandsonsltd | pallion | sunderland | shipbuilding | shipyard | industry | industrial | hull | construction | northbank | ship | vessel | riverwear | wearside | cargoship | supportblocks | northeastengland | builtinsunderland | constructionwork | development | structure | frame | platform | components | archives | industrialheritage | blackandwhitephotograph | digitalimage | fascinating | impressive | interesting | unusual | unitedkingdom | transportation | maritimeheritage | shipbuildingheritage | abstract | 27september1956 | pallionyard | progress | progression | progressionphotographs | river | bank | land | blur | grain | mark | sky | daylight | debris | reflection | buildings | wall | roof | label | letters | digit | ladder | hose | sections | pile | parts | production | northbankshull

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7.345 Vascular Development in Life, Disease and Cancer Medicine (MIT) 7.345 Vascular Development in Life, Disease and Cancer Medicine (MIT)

Description

The growth of blood vessels, a process known as angiogenesis, is one of the earliest events in mammalian development and is regulated by a sensitive interplay of growth factors and other molecules. In this course, we will discuss the key molecular regulators of blood vessel development as well as the techniques and experimental systems that have been utilized by vascular biologists. We will also examine the success of several anti-angiogenic treatments that have been approved by the Food and Drug Administration (FDA), that inhibit the pro-angiogenic vascular endothelial growth factor, VEGF, and that are now being used to treat age-related macular degeneration. Finally, we will explore how during the course of cancer progression, establishment of a blood supply into a tumor can lead to the The growth of blood vessels, a process known as angiogenesis, is one of the earliest events in mammalian development and is regulated by a sensitive interplay of growth factors and other molecules. In this course, we will discuss the key molecular regulators of blood vessel development as well as the techniques and experimental systems that have been utilized by vascular biologists. We will also examine the success of several anti-angiogenic treatments that have been approved by the Food and Drug Administration (FDA), that inhibit the pro-angiogenic vascular endothelial growth factor, VEGF, and that are now being used to treat age-related macular degeneration. Finally, we will explore how during the course of cancer progression, establishment of a blood supply into a tumor can lead to the

Subjects

angiogenesis | angiogenesis | growth factors | growth factors | VEGF | VEGF | microscopic visualization | microscopic visualization | intravital imaging | intravital imaging | anti-angiogenic treatments | anti-angiogenic treatments | macular degeneration | macular degeneration | cancer progression | cancer progression | tumor blood vessels | tumor blood vessels

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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CMS.608 Game Design (MIT)

Description

An historical examination and analysis of the evolution and development of games and game mechanics. Topics include a large breadth of genres and types of games, including sports, game shows, games of chance, schoolyard games, board games, roleplaying games, and digital games. Students submit essays documenting research and analysis of a variety of traditional and eclectic games. Project teams required to design, develop, and thoroughly test their original games.

Subjects

a | games | narrative | playtesting | student work | student notes | chance | competition | information | probability | strategy | theory | symbolism | rules | gambling | emergence | progression | randomness | cooperation

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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CMS.608 Game Design (MIT)

Description

This course provides practical instruction in the design and analysis of non-digital games. Students cover the texts, tools, references and historical context to analyze and compare game designs across a variety of genres, including sports, game shows, games of chance, card games, schoolyard games, board games, and role–playing games. In teams, students design, develop, and thoroughly test their original games to understand the interaction and evolution of game rules. Students taking the graduate version complete additional assignments.

Subjects

games | puzzles | narrative | playtestin | chance | competition | strategy | rules | gambling | emergence | progression | randomness | cooperation | iterative design | prototyping | game mechanics | aesthetics

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Auditorium from the balcony at the Paramount Theatre, Newcastle

Description

Subjects

paramounttheatre | theatre | cinema | pilgrimstreet | newcastleupontyne | odeoncinema | 1930s | architecture | tyneside | northeastengland | artdeco | auditorium | magnificent | luxurious | historic | lights | lighting | decor | furniture | interior | balcony | socialhistory | blackandwhitephotograph | digitalimage | archives | industry | artanddesign | abstract | industrialheritage | construction | progress | progression | development | sructure | building | room | arena | entertainment | show | seating | curtain | stage | decoration | pattern | interesting | unusual | compelling | beautiful | september1931 | 7september1931 | opening | odeon | 1939 | luxuriousdécor | elegance | beauty | unitedkingdom | closure | 2002 | demolished | 2017 | northumberlandnewcastlesociety | newcastle | heritage | rail | fabric | grain | mark | discolouration | extraudinary | arts

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Coal staithes in the South Docks, Sunderland

Description

No. 1 and No. 2 coal belt conveyors in operation at the South Docks, Sunderland, c1929 (TWAM ref. 3768/8). Each of these was capable of shipping 750 tons of coal per hour. This set of images celebrates the 300th Anniversary of the establishment of the Port of Sunderland. The port authority was constituted in 1717 by Act of Parliament, which appointed the River Wear Commissioners to manage and improve the harbour and river. Since then the port has changed beyond recognition with the construction of piers, docks and quays and the dredging of the River Wear to make it wider and deeper. These developments were vital to the coal trade on which the region?s prosperity depended. The improvement of the river was also essential to the success of shipbuilding in Sunderland as well as allied industries such as marine engineering and ship repairing. These images are a reflection of Sunderland?s proud industrial history. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

portofsunderland | sunderland | riverwear | historic | heritage | southdocks | docks | coal | cargo | 1920s | shipping | coalbeltconveyors | coalstaithes | industry | industrial | trade | industrialheritage | northeastofengland | unitedkingdom | port | no1andno2coalbeltconveyors | belt | c1929 | 750tonsofcoal | perhour | portauthority | riverwearcommissioners | construction | development | progress | progression | river | bank | land | coaltrade | shipbuildingheritage | maritimeheritage | archives | abstract | blackandwhitephotograph | digitalimage | debris | blur | grain | mark | frame | cabin | structure | vessel | label | rail | deck | benton | vent | cylinder | chimney | panel | components | rope | daylight | fascinating | compelling | interesting | unusual | vehicle | wheel | transport | transportation | horse | cart | window | wall | roof | sky | water

License

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The wheelhouse on 'Nicola'

Description

View of wheelhouse on ?Nicola? the first SD14 to be built by Austin & Pickersgill at the Southwick shipyard, Sunderland (TWAM ref. DT.TUR/4/3732H). This set celebrates the ?Nicola?, the first in a long line of standard ships designed by the Sunderland shipyard of Austin & Pickersgill Ltd. The images document her construction from October 1967 through to her completion in February 1968. The shipbuilders commissioned the Newcastle-based firm Turners (Photography) Ltd to take weekly progress shots of the ?Nicola? and these images have given us a unique view of her development. She was the first SD14 to be completed (the name stands for ?Shelter Deck 14,000 tons deadweight?) and was designed as a replacement for the surviving ?Liberty ships?, built by American yards during the Second World War. Those Liberty ships had played a vital role in the Allied victory but by the 1960s they were fast approaching the end of their working lives. The SD14 developed by Austin & Pickersgill met the demand for economic and reliable cargo ships. The simplicity of the design meant that it could be marketed by the shipbuilders at a very competitive price. It?s success is reflected by the fact that over the course of 20 years 211 ships were built to the SD14 design by Austin Pickersgill and its licensees. Sunderland can be very proud of its remarkable shipbuilding and engineering history and the SD14 is one the City?s finest achievements. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

nicola | industry | austinpickersgillltd | sunderland | shipbuilding | sd14 | southwick | shipyard | riverwear | wheelhouse | cabin | ship | vessel | shipbuildingheritage | maritimeheritage | industrialheritage | abstract | colourphotograph | digitalimage | archives | documentation | northeastofengland | impressive | unitedkingdom | interesting | fascinating | unusual | steeringwheel | october1967february1968 | progress | progression | development | construction | structure | production | nicolathefirstsd14 | standardship | sunderlandshipyard | turnersphotographyltd | shelterdeck14000tonsdeadweight | libertyships | replacement | cargoship | economics | transportation | controls | components | window | glass | interior | room | wall | shadow | floor | ceiling | beam | light | rail | platform | lever | cord | daylight | cylinder | container | debris | blur | grain | mark | door | handle | detail | engineeringhistory | communications | box | pipe

License

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The Newcastle side of the Tyne Bridge

Description

Subjects

tynebridge | tyneside | northeastengland | bridges | newcastleupontyne | gateshead | civilengineering | blackandwhitephotograph | girders | construction | iconic | guildhall | sandhill | quayside | rivertyne | rivers | digitalimage | archives | industry | industrialheritage | maritimeheritage | shipbuildingheritage | buildings | structure | bridge | crossing | river | bank | land | buildingthetynebridge | northeastofengland | unitedkingdom | newcastle | newcastleside | development | progress | progression | 2february1928 | city | urban | northeast | iconiclandmark | jamesbaconsons | march1927tooctober1928 | jamesgeddie | chiefassistantengineer | dormanlongcoltd | middlesbrough | impressive | magnificent | unusual | fascinating | interesting | vessel | daylight | shadow | window | wall | roof | chimney | smoke | sky | grain | blur | mark | debris | components | pile | crane | vehicle | transportation | infrastructure | economy | jobs | workers

License

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View of the Tyne Bridge from Gateshead

Description

Subjects

tynebridge | tyneside | northeastengland | bridges | newcastleupontyne | gateshead | civilengineering | blackandwhitephotograph | girders | construction | iconic | swingbridge | guildhall | quayside | rivertyne | rivers | view | buildingthetynebridge | 2february1928 | twohalves | sides | iconiclandmark | northeast | northeastofengland | crossing | structure | development | progress | progression | unitedkingdom | industrialheritage | archives | industry | digitalimage | river | bank | jamesbaconsons | march1927tooctober1928 | jamesgeddie | chiefassistantengineer | engineering | design | dormanlongcoltd | middlesbrough | buildings | land | sky | crane | components | debris | slope | grass | soil | containers | pile | lightshade | post | wall | door | roof | supports | platform | fascinating | interesting | impressive | unusual | blur | grain | mark | float | signage | letters | sign | vessel | maritimeheritage

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Nordic Chieftain under construction

Description

View of the OBO carrier 'Nordic Chieftain' under construction at the North Sands shipyard, Sunderland, February 1974 (TWAM ref. DT.TUR/2/62742C). This set celebrates the achievements of the famous Sunderland shipbuilding firm Joseph L. Thompson & Sons. The company?s origins date back to 1846 when the firm was known as Robert Thompson & Sons. Robert Thompson senior died in 1860, leaving his second son Joseph Lowes Thompson in control. In 1870 the shipyard completed its last wooden vessel and was then adapted for iron shipbuilding. By 1880 the firm had expanded its operations over much of North Sands and in 1884 completed the construction of Manor Quay, which served as fitting out and repair facilities. For many years in the late nineteenth century the yard was the most productive in Sunderland and in 1894 had the fourth largest output of any shipyard in the world. The Depression affected the firm severely in the early 1930s and no vessels were launched from 1931 to 1934. However, during those years the company developed a hull design giving greater efficiency and economy in service. During the Second World War the prototype developed by Joseph L. Thompson & Sons proved so popular that it was used by the US Government as the basis of over 2,700 Liberty ships built at American shipyards between 1942 and 1945. After the War the North Sands shipyard went on to build many fine cargo ships, oil tankers and bulk carriers. Sadly the shipyard closed in 1979, although it briefly reopened in 1986 to construct the crane barge ITM Challenger. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

sunderland | shipbuilding | northsandssunderland | nordicchieftain | riverwear | shipyard | cranes | obocarrier | industry | industrial | wearside | northeastengland | ship | maritimeheritage | shipbuildingheritage | industrialheritage | blackandwhitephotograph | archives | abstract | northsandsshipyard | northeastofengland | unitedkingdom | fascinating | impressive | interesting | unusual | vessel | transportation | construction | development | progress | progression | february1974 | path | crane | machinery | platform | grain | road | blur | mark | buildings | river | josephlthompsonsons | robertthompsonsons | robertthompsonsenior | josephlowesthompson | iron | production | northsands | manorquay | fittingout | repairs | facilities | components | service | economy | ladder | debris | boat | workers | sky | land | water | rope | roof | wall | deck | opening | window | frame | glass | cargo

License

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View from the High Level Bridge

Description

Subjects

tynebridge | tyneside | northeastengland | bridges | newcastleupontyne | gateshead | quayside | civilengineering | blackandwhitephotograph | girders | construction | iconic | rivertyne | cranes | interesting | swingbridge | label | digitalimage | archives | industry | industrialheritage | northeastofengland | unitedkingdom | city | urban | view | glimpse | buildingthetynebridge | buildings | sky | land | bank | structure | development | bridge | vessel | daylight | shine | water | river | highlevelbridge | newcastle | 6march1928 | iconiclandmarks | northeast | jamesbaconsons | documentation | progress | progression | march1927tooctober1928 | jamesgeddie | chiefassistantengineer | dormanlongcoltd | middlesbrough | impressive | unusual | fascinating | refelection | deck | transportation | mast | chimney | platform | passage | clock | wall | roof | grain | mark | debris | blur | number | letter

License

No known copyright restrictions

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Networking: What, Why and How? - Mini Lecture

Description

A mini-lecture about Networking. This short lecture will introduce you to the concept and practice of networking and look at why it is useful to you as soon to be, or recent graduate. We will then look at ways that you can develop and build your network and networking skills in order to become more successful in your personal and professional life.

Subjects

network | networking | contacts | career progression | relationships | employability | ukoer | administrative studies | N000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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Bottom shell plating of Northbank is put in place

Description

Bottom shell plating of the cargo ship 'Northbank' is put in place at the shipyard of William Doxford & Sons, Sunderland, 20 September 1956 (TWAM ref. DS.DOX/4/PH/1/819/1/3) This album documents the construction of the cargo ship ?Northbank? by the famous shipbuilding firm William Doxford & Sons at its Pallion yard, Sunderland. Most of these images are progress photographs, taken a week apart between September 1956 and January 1957 from approximately the same spot. They give a fascinating insight into how the vessel was built. (Copyright) We're happy for you to share this digital image within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk.

Subjects

williamdoxfordandsonsltd | pallion | sunderland | shipbuilding | shipyard | industry | industrial | shellplating | construction | hull | northbank | ship | vessel | riverwear | wearside | cargoship | supportblocks | northeastengland | bottomshellplating | builtinsunderland | production | structure | platform | supports | pile | components | debris | parts | sections | maritimeheritage | shipbuildingheritage | industrialheritage | abstract | blackandwhitephotograph | digitalimage | archives | fascinating | impressive | unusual | interesting | compelling | unitedkingdom | transportation | 20september1956 | progress | progression | pallionyard | progressphotographs | land | bank | river | grain | mark | blur | daylight | glare | timber | ladder | buildings | wall | roof | sky | processwork | process | reflection | opening | view | glimpse | setting | label | date | digit | letter

License

No known copyright restrictions

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Tyne & Wear Archives & Museums | FlickR

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'Nicola's stern frame in place

Description

Stern frame in place on ?Nicola?, the first SD14 to be built by Austin & Pickersgill, 20 November 1967 (TWAM ref. DT.TUR/2/51857A). This set celebrates the ?Nicola?, the first in a long line of standard ships designed by the Sunderland shipyard of Austin & Pickersgill Ltd. The images document her construction from October 1967 through to her completion in February 1968. The shipbuilders commissioned the Newcastle-based firm Turners (Photography) Ltd to take weekly progress shots of the ?Nicola? and these images have given us a unique view of her development. She was the first SD14 to be completed (the name stands for ?Shelter Deck 14,000 tons deadweight?) and was designed as a replacement for the surviving ?Liberty ships?, built by American yards during the Second World War. Those Liberty ships had played a vital role in the Allied victory but by the 1960s they were fast approaching the end of their working lives. The SD14 developed by Austin & Pickersgill met the demand for economic and reliable cargo ships. The simplicity of the design meant that it could be marketed by the shipbuilders at a very competitive price. It?s success is reflected by the fact that over the course of 20 years 211 ships were built to the SD14 design by Austin Pickersgill and its licensees. Sunderland can be very proud of its remarkable shipbuilding and engineering history and the SD14 is one the City?s finest achievements. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

nicola | industry | austinpickersgillltd | sunderland | shipbuilding | sd14 | southwick | shipyard | riverwear | maritimeheritage | blackandwhitephotograph | sternframe | platform | construction | 20november1967 | standardship | october1967 | february1968 | newcastle | turnersphotographyltd | progression | development | shelterdeck14000tonsdeadweight | libertyships | replacement | alliedvictory | secondworldwar | economic | reliable | cargoships | engineering | crane | steel | metal | frame | plate | scaffold | timber | debris | cylinder | worker | stairs | bolt | nut | wire | bridge | soil | parts | sky | ground | unusual | striking

License

No known copyright restrictions

Site sourced from

Tyne & Wear Archives & Museums | FlickR

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Tyne Bridge roadway under construction

Description

Subjects

tynebridge | tyneside | northeastengland | bridges | newcastleupontyne | gateshead | civilengineering | blackandwhitephotograph | girders | construction | iconic | rivertyne | cranes | interesting | workers | unitedkingdom | industrialheritage | crossing | bridge | structure | road | platform | development | landmark | digitalimage | archives | industry | roadway | 18may1928 | northeast | jamesbaconsons | newcastle | documentation | march1927tooctober1928 | jamesgeddie | chiefassistantengineer | dormanlongcoltd | middlesbrough | impressive | fascinating | unusual | buildingthetynebridge | tools | sky | rail | timber | cap | coat | trousers | crease | debris | grain | cord | rope | crane | machinery | mechanical | bolt | panel | puddle | water | label | identification | working | progress | progression | cylinder | cog | cabin | blur | reflection | daylight | team | dirt | tynebridgeroadway

License

No known copyright restrictions

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Double bottoms near completion

Description

Double bottoms near completion of ?Nicola?, the first SD14 to be built by Austin & Pickersgill, 23 October 1967 (TWAM ref. DT.TUR/2/51703B). This set celebrates the ?Nicola?, the first in a long line of standard ships designed by the Sunderland shipyard of Austin & Pickersgill Ltd. The images document her construction from October 1967 through to her completion in February 1968. The shipbuilders commissioned the Newcastle-based firm Turners (Photography) Ltd to take weekly progress shots of the ?Nicola? and these images have given us a unique view of her development. She was the first SD14 to be completed (the name stands for ?Shelter Deck 14,000 tons deadweight?) and was designed as a replacement for the surviving ?Liberty ships?, built by American yards during the Second World War. Those Liberty ships had played a vital role in the Allied victory but by the 1960s they were fast approaching the end of their working lives. The SD14 developed by Austin & Pickersgill met the demand for economic and reliable cargo ships. The simplicity of the design meant that it could be marketed by the shipbuilders at a very competitive price. It?s success is reflected by the fact that over the course of 20 years 211 ships were built to the SD14 design by Austin Pickersgill and its licensees. Sunderland can be very proud of its remarkable shipbuilding and engineering history and the SD14 is one the City?s finest achievements. (Copyright) We're happy for you to share these digital images within the spirit of The Commons. Please cite 'Tyne & Wear Archives & Museums' when reusing. Certain restrictions on high quality reproductions and commercial use of the original physical version apply though; if you're unsure please email archives@twmuseums.org.uk

Subjects

nicola | industry | austinpickersgillltd | sunderland | shipbuilding | sd14 | southwick | shipyard | riverwear | industrialheritage | ladder | steps | maritimeheritage | shipbuildingheritage | northeastofengland | unitedkingdom | abstract | digitalimage | blackandwhitephotograph | archives | impressive | unusual | nicolathefirstsd14 | construction | development | structure | productionline | workmen | workers | sunderlandshipyard | turnersphotographyltd | commission | progression | shelterdeck14000tonsdeadweight | libertyships | cargoship | engineering | land | bank | river | rivertyne | buildings | wall | roof | sky | crane | daylight | shadow | striking | magnificent | shade | rope | tools | working | debris | timber | pile | water | parts | window | cylinder | hole | vent | clothing | hat | glimpse | yard | remarkable | grain | standardships | design

License

No known copyright restrictions

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Lecture 25: Fiction and Stories in Games

Description

Description: Many games incorporate story elements, to drive the plot, set the scene, create engaging characters, etc. Some even use player actions to build an open-ended adventure. Clara Fernandez-Vara talks about how and why to use stories in games. Instructors/speakers: Philip Tan, Jason Begy, Clara Fernandez-Vara (Singapore-MIT GAMBIT Game Lab)Keywords: narrative, environmental storytelling, roleplaying, emergence, storybuilding, non-digital games, digital games, game state, stories, fiction, setting, characters, theme, progression, improvisation, micronarrative, premise, game event, game mechanic, ethics, board games, card gamesTranscript: PDFSubtitles: SRTAudio - download: Internet Archive (MP3)Audio - download: iTunes U (MP3)(CC BY-NC-SA)

Subjects

narrative | environmental storytelling | roleplaying | emergence | storybuilding | non-digital games | digital games | game state | stories | fiction | setting | characters | theme | progression | improvisation | micronarrative | premise | game event | game mechanic | ethics | board games | card games

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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