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8.421 Atomic and Optical Physics I (MIT) 8.421 Atomic and Optical Physics I (MIT)

Description

Includes audio/video content: AV lectures. This is the first of a two-semester subject sequence that provides the foundations for contemporary research in selected areas of atomic and optical physics. Topics covered include the interaction of radiation with atoms: resonance; absorption, stimulated and spontaneous emission; methods of resonance, dressed atom formalism, masers and lasers, cavity quantum electrodynamics; structure of simple atoms, behavior in very strong fields; fundamental tests: time reversal, parity violations, Bell's inequalities; and experimental methods. Includes audio/video content: AV lectures. This is the first of a two-semester subject sequence that provides the foundations for contemporary research in selected areas of atomic and optical physics. Topics covered include the interaction of radiation with atoms: resonance; absorption, stimulated and spontaneous emission; methods of resonance, dressed atom formalism, masers and lasers, cavity quantum electrodynamics; structure of simple atoms, behavior in very strong fields; fundamental tests: time reversal, parity violations, Bell's inequalities; and experimental methods.

Subjects

atom | atom | atomic and optical physics | atomic and optical physics | resonance | resonance | resonance frequency | resonance frequency | harmonic oscillator | harmonic oscillator | oscillation frequency | oscillation frequency | magnetic field | magnetic field | electric field | electric field | Landau-Zener problem | Landau-Zener problem | lamb shift | lamb shift | line broadening | line broadening | coherence | coherence

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12.620J Classical Mechanics: A Computational Approach (MIT) 12.620J Classical Mechanics: A Computational Approach (MIT)

Description

12.620J covers the fundamental principles of classical mechanics, with a modern emphasis on the qualitative structure of phase space. The course uses computational ideas to formulate the principles of mechanics precisely. Expression in a computational framework encourages clear thinking and active exploration.The following topics are covered: the Lagrangian formulation, action, variational principles, and equations of motion, Hamilton's principle, conserved quantities, rigid bodies and tops, Hamiltonian formulation and canonical equations, surfaces of section, chaos, canonical transformations and generating functions, Liouville's theorem and Poincaré integral invariants, Poincaré-Birkhoff and KAM theorems, invariant curves and cantori, nonlinear resonances, resonance ov 12.620J covers the fundamental principles of classical mechanics, with a modern emphasis on the qualitative structure of phase space. The course uses computational ideas to formulate the principles of mechanics precisely. Expression in a computational framework encourages clear thinking and active exploration.The following topics are covered: the Lagrangian formulation, action, variational principles, and equations of motion, Hamilton's principle, conserved quantities, rigid bodies and tops, Hamiltonian formulation and canonical equations, surfaces of section, chaos, canonical transformations and generating functions, Liouville's theorem and Poincaré integral invariants, Poincaré-Birkhoff and KAM theorems, invariant curves and cantori, nonlinear resonances, resonance ov

Subjects

classical mechanics | classical mechanics | phase space | phase space | computation | computation | Lagrangian formulation | Lagrangian formulation | action | action | variational principles | variational principles | equations of motion | equations of motion | Hamilton's principle | Hamilton's principle | conserved quantities | conserved quantities | rigid bodies and tops | rigid bodies and tops | Hamiltonian formulation | Hamiltonian formulation | canonical equations | canonical equations | surfaces of section | surfaces of section | chaos | chaos | canonical transformations | canonical transformations | generating functions | generating functions | Liouville's theorem | Liouville's theorem | Poincar? integral invariants | Poincar? integral invariants | Poincar?-Birkhoff | Poincar?-Birkhoff | KAM theorem | KAM theorem | invariant curves | invariant curves | cantori | cantori | nonlinear resonances | nonlinear resonances | resonance overlap | resonance overlap | transition to chaos | transition to chaos | chaotic motion | chaotic motion | 12.620 | 12.620 | 6.946 | 6.946 | 8.351 | 8.351

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20.320 Analysis of Biomolecular and Cellular Systems (MIT) 20.320 Analysis of Biomolecular and Cellular Systems (MIT)

Description

This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling. This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.

Subjects

biological engineering | biological engineering | kinase | kinase | PyMOL | PyMOL | PyRosetta | PyRosetta | MATLAB | MATLAB | Michaelis-Menten | Michaelis-Menten | bioreactor | bioreactor | bromodomain | bromodomain | protein-ligand interactions | protein-ligand interactions | titration analysis | titration analysis | fractional separation | fractional separation | isothermal titration calorimetry | isothermal titration calorimetry | ITC | ITC | mass spectrometry | mass spectrometry | MS | MS | co-immunoprecipitation | co-immunoprecipitation | Co-IP | Co-IP | Forster resonance energy transfer | Forster resonance energy transfer | FRET | FRET | primary ligation assay | primary ligation assay | PLA | PLA | surface plasmon resonance | surface plasmon resonance | SPR | SPR | enzyme kinetics | enzyme kinetics | kinase engineering | kinase engineering | competitive inhibition | competitive inhibition | epidermal growth factor receptor | epidermal growth factor receptor | mitogen-activated protein kinase | mitogen-activated protein kinase | MAPK | MAPK | genome editing | genome editing | Imatinib | Imatinib | Gleevec | Gleevec | Glivec | Glivec | drug delivery | drug delivery | kinetics of molecular processes | kinetics of molecular processes | dynamics of molecular processes | dynamics of molecular processes | kinetics of cellular processes | kinetics of cellular processes | dynamics of cellular processes | dynamics of cellular processes | intracellular scale | intracellular scale | extracellular scale | extracellular scale | and cell population scale | and cell population scale | biotechnology applications | biotechnology applications | gene regulation networks | gene regulation networks | nucleic acid hybridization | nucleic acid hybridization | signal transduction pathways | signal transduction pathways | cell populations in tissues | cell populations in tissues | cell populations in bioreactors | cell populations in bioreactors | experimental methods | experimental methods | quantitative analysis | quantitative analysis | computational modeling | computational modeling

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HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT) HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT)

Description

This team taught, multidisciplinary course covers the fundamentals of magnetic resonance imaging relevant to the conduct and interpretation of human brain mapping studies. The challenges inherent in advancing our knowledge about brain function using fMRI are presented first to put the work in context. The course then provides in depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include fMRI experimental design including block design, event related and exploratory data analysis methods, building and applying statistical mod This team taught, multidisciplinary course covers the fundamentals of magnetic resonance imaging relevant to the conduct and interpretation of human brain mapping studies. The challenges inherent in advancing our knowledge about brain function using fMRI are presented first to put the work in context. The course then provides in depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include fMRI experimental design including block design, event related and exploratory data analysis methods, building and applying statistical mod

Subjects

medical lab | medical lab | medical technology | medical technology | magnetic resonance imaging | magnetic resonance imaging | fMRI | fMRI | signal processing | signal processing | human brain mapping | human brain mapping | function | function | image formation physics | image formation physics | metabolism | metabolism | psychology | psychology | image signals | image signals | parenchymal | parenchymal | cerebrovascular neuroanatomy | cerebrovascular neuroanatomy | functional data analysis | functional data analysis | experimental design | experimental design | statistical models | statistical models | human subjects | human subjects | informed consent | informed consent | institutional review board requirements | institutional review board requirements | safety | safety | medical | medical | brain scan | brain scan

License

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12.620J Classical Mechanics: A Computational Approach (MIT)

Description

12.620J covers the fundamental principles of classical mechanics, with a modern emphasis on the qualitative structure of phase space. The course uses computational ideas to formulate the principles of mechanics precisely. Expression in a computational framework encourages clear thinking and active exploration.The following topics are covered: the Lagrangian formulation, action, variational principles, and equations of motion, Hamilton's principle, conserved quantities, rigid bodies and tops, Hamiltonian formulation and canonical equations, surfaces of section, chaos, canonical transformations and generating functions, Liouville's theorem and Poincaré integral invariants, Poincaré-Birkhoff and KAM theorems, invariant curves and cantori, nonlinear resonances, resonance ov

Subjects

classical mechanics | phase space | computation | Lagrangian formulation | action | variational principles | equations of motion | Hamilton's principle | conserved quantities | rigid bodies and tops | Hamiltonian formulation | canonical equations | surfaces of section | chaos | canonical transformations | generating functions | Liouville's theorem | Poincar? integral invariants | Poincar?-Birkhoff | KAM theorem | invariant curves | cantori | nonlinear resonances | resonance overlap | transition to chaos | chaotic motion | 12.620 | 6.946 | 8.351

License

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9.71 Functional MRI of High-Level Vision (MIT) 9.71 Functional MRI of High-Level Vision (MIT)

Description

This course covers the basics of fMRI, the strengths and limitations of fMRI compared to other techniques, and the design and analysis of fMRI experiments, focusing primarily on experiments on high-level vision. Upon completion, students should be able to understand and critique published fMRI papers, have a good grasp on what is known about high-level vision from fMRI, and design their own fMRI experiments. This course covers the basics of fMRI, the strengths and limitations of fMRI compared to other techniques, and the design and analysis of fMRI experiments, focusing primarily on experiments on high-level vision. Upon completion, students should be able to understand and critique published fMRI papers, have a good grasp on what is known about high-level vision from fMRI, and design their own fMRI experiments.

Subjects

functional magnetic resonance imaging (fMRI) | functional magnetic resonance imaging (fMRI) | neural activity | neural activity | human | human | brain | brain | noninvasive | noninvasive | resolution | resolution | high-level vision | high-level vision | object recognition | object recognition | visual attention | visual attention | perceptual awareness | perceptual awareness | visually guided action | visually guided action | visual memory | visual memory

License

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5.33 Advanced Chemical Experimentation and Instrumentation (MIT) 5.33 Advanced Chemical Experimentation and Instrumentation (MIT)

Description

5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.AcknowledgementsThe materials for 5.33 reflect the work of many faculty members associated with this course over the years. WARNING NOTICEThe experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or imp 5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.AcknowledgementsThe materials for 5.33 reflect the work of many faculty members associated with this course over the years. WARNING NOTICEThe experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or imp

Subjects

advance chemical experimentation | advance chemical experimentation | chemistry laboratory | chemistry laboratory | chemistry lab | chemistry lab | molecular spectroscopy | molecular spectroscopy | acetylene | acetylene | magnetic resonance spectroscopy | magnetic resonance spectroscopy | ESR | ESR | time-resolved | time-resolved | electronic spectroscopy | electronic spectroscopy | nitrogen scission | nitrogen scission | molybdenum (III) xylidine | molybdenum (III) xylidine

License

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5.46 Organic Structure Determination (MIT) 5.46 Organic Structure Determination (MIT)

Description

This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides. This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides.

Subjects

organic structure determination | organic structure determination | relative configuration | relative configuration | elemental analysis | elemental analysis | mass spectometry | mass spectometry | index of hydrogen deficiency | index of hydrogen deficiency | EA | EA | MS | MS | IHD | IHD | infrared spectroscopy | infrared spectroscopy | IR | IR | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | NMR | NMR | chemical equivalence | chemical equivalence | non-equivalence | non-equivalence | topicity | topicity | spin-spin splitting | spin-spin splitting | J coupling | J coupling | chemical shift | chemical shift

License

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8.05 Quantum Physics II (MIT) 8.05 Quantum Physics II (MIT)

Description

This course, along with the next course in this sequence (8.06, Quantum Physics III) in a two-course sequence covering quantum physics with applications drawn from modern physics. General formalism of quantum mechanics: states, operators, Dirac notation, representations, measurement theory. Harmonic oscillator: operator algebra, states. Quantum mechanics in three-dimensions: central potentials and the radial equation, bound and scattering states, qualitative analysis of wavefunctions. Angular momentum: operators, commutator algebra, eigenvalues and eigenstates, spherical harmonics. Spin: Stern-Gerlach devices and measurements, nuclear magnetic resonance, spin and statistics. Addition of angular momentum: Clebsch-Gordan series and coefficients, spin systems, and allotropic forms of hydrogen This course, along with the next course in this sequence (8.06, Quantum Physics III) in a two-course sequence covering quantum physics with applications drawn from modern physics. General formalism of quantum mechanics: states, operators, Dirac notation, representations, measurement theory. Harmonic oscillator: operator algebra, states. Quantum mechanics in three-dimensions: central potentials and the radial equation, bound and scattering states, qualitative analysis of wavefunctions. Angular momentum: operators, commutator algebra, eigenvalues and eigenstates, spherical harmonics. Spin: Stern-Gerlach devices and measurements, nuclear magnetic resonance, spin and statistics. Addition of angular momentum: Clebsch-Gordan series and coefficients, spin systems, and allotropic forms of hydrogen

Subjects

General formalism of quantum mechanics: states | General formalism of quantum mechanics: states | operators | operators | Dirac notation | Dirac notation | representations | representations | measurement theory | measurement theory | Harmonic oscillator: operator algebra | Harmonic oscillator: operator algebra | states | states | Quantum mechanics in three-dimensions: central potentials and the radial equation | Quantum mechanics in three-dimensions: central potentials and the radial equation | bound and scattering states | bound and scattering states | qualitative analysis of wavefunctions | qualitative analysis of wavefunctions | Angular momentum: operators | Angular momentum: operators | commutator algebra | commutator algebra | eigenvalues and eigenstates | eigenvalues and eigenstates | spherical harmonics | spherical harmonics | Spin: Stern-Gerlach devices and measurements | Spin: Stern-Gerlach devices and measurements | nuclear magnetic resonance | nuclear magnetic resonance | spin and statistics | spin and statistics | Addition of angular momentum: Clebsch-Gordan series and coefficients | Addition of angular momentum: Clebsch-Gordan series and coefficients | spin systems | spin systems | allotropic forms of hydrogen | allotropic forms of hydrogen | Angular momentum | Angular momentum | Harmonic oscillator | Harmonic oscillator | operator algebra | operator algebra | Spin | Spin | Stern-Gerlach devices and measurements | Stern-Gerlach devices and measurements | central potentials and the radial equation | central potentials and the radial equation | Clebsch-Gordan series and coefficients | Clebsch-Gordan series and coefficients | quantum physics | quantum physics

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II "Junior Lab" (MIT) II "Junior Lab" (MIT)

Description

Junior Lab consists of two undergraduate courses in experimental physics. The courses are offered by the MIT Physics Department, and are usually taken by Juniors (hence the name). Officially, the courses are called Experimental Physics I and II and are numbered 8.13 for the first half, given in the fall semester, and 8.14 for the second half, given in the spring. The purposes of Junior Lab are to give students hands-on experience with some of the experimental basis of modern physics and, in the process, to deepen their understanding of the relations between experiment and theory, mostly in atomic and nuclear physics. Each term, students choose 5 different experiments from a list of 21 total labs. Junior Lab consists of two undergraduate courses in experimental physics. The courses are offered by the MIT Physics Department, and are usually taken by Juniors (hence the name). Officially, the courses are called Experimental Physics I and II and are numbered 8.13 for the first half, given in the fall semester, and 8.14 for the second half, given in the spring. The purposes of Junior Lab are to give students hands-on experience with some of the experimental basis of modern physics and, in the process, to deepen their understanding of the relations between experiment and theory, mostly in atomic and nuclear physics. Each term, students choose 5 different experiments from a list of 21 total labs.

Subjects

Junior Lab | Junior Lab | experimental | experimental | atomic | atomic | nuclear | nuclear | physics | physics | optics | optics | photoelectric effect | photoelectric effect | poisson | poisson | statistics | statistics | electromagnetic pulse | electromagnetic pulse | compton scattering | compton scattering | Franck-Hertz experiment | Franck-Hertz experiment | relativistic dynamics | relativistic dynamics | nuclear magnetic resonance | nuclear magnetic resonance | spin echoes | spin echoes | cosmic-ray muons | cosmic-ray muons | Rutherford Scattering | Rutherford Scattering | emission spectra | emission spectra | neutron physics | neutron physics | Johnson noise | Johnson noise | shot noise | shot noise | quantum mechanics | quantum mechanics | alpha decay | alpha decay | radio astrophysics | radio astrophysics | Zeeman effect | Zeeman effect | rubidium | rubidium | M?ssbauer | M?ssbauer | spectroscopy | spectroscopy | X-Ray physics | X-Ray physics | superconductivity | superconductivity | Doppler-free | Doppler-free | laser | laser

License

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22.920 A Hands-On Introduction to Nuclear Magnetic Resonance (MIT) 22.920 A Hands-On Introduction to Nuclear Magnetic Resonance (MIT)

Description

Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging. Hands-on introduction to NMR presenting background in classical theory and instrumentation. Each lecture is followed by lab experiments to demonstrate ideas presented during the lecture and to familiarize students with state-of-the-art NMR instrumentation. Experiments cover topics ranging from spin dynamics to spectroscopy, and include imaging.

Subjects

nuclear spin | nuclear spin | magnetic resonance | magnetic resonance | rotating | rotating | otating frame | otating frame | rotating frame | rotating frame | RF pulses | RF pulses | Bloch's equations | Bloch's equations | magnetic field gradients | magnetic field gradients | k-space | k-space | diffusion | diffusion | spin echoes | spin echoes | NMR imaging in 2D | NMR imaging in 2D | slice selection | slice selection | flow studies | flow studies | NMR spectroscopy | NMR spectroscopy | chemical shifts | chemical shifts | spin-spin couplings | spin-spin couplings | Two dimensional NMR methods | Two dimensional NMR methods | COSY experiment | COSY experiment

License

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5.33 Advanced Chemical Experimentation and Instrumentation (MIT) 5.33 Advanced Chemical Experimentation and Instrumentation (MIT)

Description

5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course. Acknowledgements The materials for 5.33 reflect the work of many faculty members associated with this course over the years. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or impleme 5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course. Acknowledgements The materials for 5.33 reflect the work of many faculty members associated with this course over the years. WARNING NOTICE The experiments described in these materials are potentially hazardous and require a high level of safety training, special facilities and equipment, and supervision by appropriate individuals. You bear the sole responsibility, liability, and risk for the implementation of such safety procedures and measures. MIT shall have no responsibility, liability, or risk for the content or impleme

Subjects

advance chemical experimentation | advance chemical experimentation | chemistry laboratory | chemistry laboratory | chemistry lab | chemistry lab | molecular spectroscopy | molecular spectroscopy | acetylene | acetylene | magnetic resonance spectroscopy | magnetic resonance spectroscopy | ESR | ESR | time-resolved | time-resolved | electronic spectroscopy | electronic spectroscopy | nitrogen scission | nitrogen scission | molybdenum (III) xylidine | molybdenum (III) xylidine

License

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5.46 Organic Structure Determination (MIT) 5.46 Organic Structure Determination (MIT)

Description

This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides. This course covers modern and advanced methods of elucidation of the structures of organic molecules, including NMR, MS, and IR (among others). The fundamental physical and chemical principles of each method will be discussed. The major emphasis of this course is on structure determination by way of interpreting the data (generally in the form of a spectrum or spectra) that each method provides.

Subjects

organic structure determination | organic structure determination | relative configuration | relative configuration | elemental analysis | elemental analysis | mass spectometry | mass spectometry | index of hydrogen deficiency | index of hydrogen deficiency | EA | EA | MS | MS | IHD | IHD | infrared spectroscopy | infrared spectroscopy | IR | IR | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | NMR | NMR | chemical equivalence | chemical equivalence | non-equivalence | non-equivalence | topicity | topicity | spin-spin splitting | spin-spin splitting | J coupling | J coupling | chemical shift | chemical shift

License

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5.13 Organic Chemistry II (MIT) 5.13 Organic Chemistry II (MIT)

Description

This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry. This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry.

Subjects

intermediate organic chemistry | intermediate organic chemistry | organic molecules | organic molecules | stereochemistry | stereochemistry | reaction mechanisms | reaction mechanisms | synthesis of organic compounds | synthesis of organic compounds | synthesis | synthesis | structure determination | structure determination | mechanism | mechanism | reactivity | reactivity | functional groups | functional groups | NMR | NMR | spectroscopy | spectroscopy | spectrometry | spectrometry | structure elucidation | structure elucidation | infrared spectroscopy | infrared spectroscopy | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | reactive intermediates | reactive intermediates | carbocations | carbocations | radicals | radicals | aromaticity | aromaticity | conjugated systems | conjugated systems | molecular orbital theory | molecular orbital theory | pericyclic reactions | pericyclic reactions

License

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8.03 Physics III (MIT) 8.03 Physics III (MIT)

Description

Mechanical vibrations and waves, simple harmonic motion, superposition, forced vibrations and resonance, coupled oscillations and normal modes, vibrations of continuous systems, reflection and refraction, phase and group velocity. Optics, wave solutions to Maxwell's equations, polarization, Snell's law, interference, Huygens's principle, Fraunhofer diffraction, and gratings. Mechanical vibrations and waves, simple harmonic motion, superposition, forced vibrations and resonance, coupled oscillations and normal modes, vibrations of continuous systems, reflection and refraction, phase and group velocity. Optics, wave solutions to Maxwell's equations, polarization, Snell's law, interference, Huygens's principle, Fraunhofer diffraction, and gratings.

Subjects

Mechanical vibrations and waves | Mechanical vibrations and waves | simple harmonic motion | simple harmonic motion | superposition | superposition | forced vibrations and resonance | forced vibrations and resonance | coupled oscillations and normal modes | coupled oscillations and normal modes | vibrations of continuous systems | vibrations of continuous systems | reflection and refraction | reflection and refraction | phase and group velocity | phase and group velocity | wave solutions to Maxwell's equations | wave solutions to Maxwell's equations | polarization | polarization | Snell's Law | Snell's Law | interference | interference | Huygens's principle | Huygens's principle | Fraunhofer diffraction | Fraunhofer diffraction | gratings | gratings

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9.71 Functional MRI of High-Level Vision (MIT) 9.71 Functional MRI of High-Level Vision (MIT)

Description

We are now at an unprecedented point in the field of neuroscience: We can watch the human brain in action as it sees, thinks, decides, reads, and remembers. Functional magnetic resonance imaging (fMRI) is the only method that enables us to monitor local neural activity in the normal human brain in a noninvasive fashion and with good spatial resolution. A large number of far-reaching and fundamental questions about the human mind and brain can now be answered using straightforward applications of this technology. This is particularly true in the area of high-level vision, the study of how we interpret and use visual information including object recognition, mental imagery, visual attention, perceptual awareness, visually guided action, and visual memory. The goals of this course are to help We are now at an unprecedented point in the field of neuroscience: We can watch the human brain in action as it sees, thinks, decides, reads, and remembers. Functional magnetic resonance imaging (fMRI) is the only method that enables us to monitor local neural activity in the normal human brain in a noninvasive fashion and with good spatial resolution. A large number of far-reaching and fundamental questions about the human mind and brain can now be answered using straightforward applications of this technology. This is particularly true in the area of high-level vision, the study of how we interpret and use visual information including object recognition, mental imagery, visual attention, perceptual awareness, visually guided action, and visual memory. The goals of this course are to help

Subjects

functional magnetic resonance imaging (fMRI) | functional magnetic resonance imaging (fMRI) | neural activity | neural activity | human | human | brain | brain | noninvasive | noninvasive | resolution | resolution | high-level vision | high-level vision | object recognition | object recognition | visual attention | visual attention | perceptual awareness | perceptual awareness | visually guided action | visually guided action | visual memory | visual memory | voxelwise analysis | voxelwise analysis | conjugate mirroring | conjugate mirroring | interleaved stimulus presentation | interleaved stimulus presentation | magnetization following excitation | magnetization following excitation | active voxels | active voxels | scanner drift | scanner drift | trial sorting | trial sorting | collinear factors | collinear factors | different model factors | different model factors | mock scanner | mock scanner | scanner session | scanner session | visual stimulation task | visual stimulation task | hemoglobin signal | hemoglobin signal | labeling plane | labeling plane | nearby voxels | nearby voxels | shimming coils | shimming coils | bias field estimation | bias field estimation | conscious encoding | conscious encoding | spiral imaging | spiral imaging | functional resolution | functional resolution | hemodynamic activity | hemodynamic activity | direct cortical stimulation | direct cortical stimulation | physiological noise | physiological noise | refractory effects | refractory effects | independent statistical tests. | independent statistical tests.

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9.458 Parkinson's Disease Workshop (MIT) 9.458 Parkinson's Disease Workshop (MIT)

Description

Parkinson's disease (PD) is a chronic, progressive, degenerative disease of the brain that produces movement disorders and deficits in executive functions, working memory, visuospatial functions, and internal control of attention. It is named after James Parkinson (1755-1824), the English neurologist who described the first case. This six-week summer workshop explored different aspects of PD, including clinical characteristics, structural neuroimaging, neuropathology, genetics, and cognitive function (mental status, cognitive control processes, working memory, and long-term declarative memory).  The workshop did not take up the topics of motor control, nondeclarative memory, or treatment.  Parkinson's disease (PD) is a chronic, progressive, degenerative disease of the brain that produces movement disorders and deficits in executive functions, working memory, visuospatial functions, and internal control of attention. It is named after James Parkinson (1755-1824), the English neurologist who described the first case. This six-week summer workshop explored different aspects of PD, including clinical characteristics, structural neuroimaging, neuropathology, genetics, and cognitive function (mental status, cognitive control processes, working memory, and long-term declarative memory).  The workshop did not take up the topics of motor control, nondeclarative memory, or treatment. 

Subjects

Parkinson's disease | Parkinson's disease | chronic progressive degenerative disease | chronic progressive degenerative disease | central nervous system | central nervous system | movement disorders | movement disorders | executive functions | executive functions | working memory | working memory | visuospatial functions | visuospatial functions | internal control of attention | internal control of attention | James Parkinson | James Parkinson | neurologist | neurologist | pathogenic mechanisms | pathogenic mechanisms | positron emission tomography (PET) | positron emission tomography (PET) | structural and functional high-field magnetic resonance imaging (MRI) | structural and functional high-field magnetic resonance imaging (MRI)

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22.51 Interaction of Radiation with Matter (MIT) 22.51 Interaction of Radiation with Matter (MIT)

Description

Basic principles of interaction of electromagnetic radiation, thermal neutrons, and charged particles with matter. Introduces classical electrodynamics, quantum theory of radiation, time-dependent perturbation theory, transition probabilities and cross sections describing interaction of various radiations with atomic systems. Applications include theory of nuclear magnetic resonance; Rayleigh, Raman, and Compton scattering; photoelectric effect; and use of thermal neutron scattering as a tool in condensed matter research. Basic principles of interaction of electromagnetic radiation, thermal neutrons, and charged particles with matter. Introduces classical electrodynamics, quantum theory of radiation, time-dependent perturbation theory, transition probabilities and cross sections describing interaction of various radiations with atomic systems. Applications include theory of nuclear magnetic resonance; Rayleigh, Raman, and Compton scattering; photoelectric effect; and use of thermal neutron scattering as a tool in condensed matter research.

Subjects

electromagnetic radiation | electromagnetic radiation | thermal neutrons | thermal neutrons | charged particles | charged particles | classical electrodynamics | classical electrodynamics | quantum theory | quantum theory | time-dependent perturbation theory | time-dependent perturbation theory | transition probabilities | transition probabilities | atomic systems | atomic systems | nuclear magnetic resonance | nuclear magnetic resonance | photoelectric effect | photoelectric effect | thermal neutron scattering | thermal neutron scattering | condensed matter research | condensed matter research

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8.05 Quantum Physics II (MIT) 8.05 Quantum Physics II (MIT)

Description

Together, this course and 8.06: Quantum Physics III cover quantum physics with applications drawn from modern physics. Topics covered in this course include the general formalism of quantum mechanics, harmonic oscillator, quantum mechanics in three-dimensions, angular momentum, spin, and addition of angular momentum. Together, this course and 8.06: Quantum Physics III cover quantum physics with applications drawn from modern physics. Topics covered in this course include the general formalism of quantum mechanics, harmonic oscillator, quantum mechanics in three-dimensions, angular momentum, spin, and addition of angular momentum.

Subjects

General formalism of quantum mechanics: states | General formalism of quantum mechanics: states | operators | operators | Dirac notation | Dirac notation | representations | representations | measurement theory | measurement theory | Harmonic oscillator: operator algebra | Harmonic oscillator: operator algebra | states | states | Quantum mechanics in three-dimensions: central potentials and the radial equation | Quantum mechanics in three-dimensions: central potentials and the radial equation | bound and scattering states | bound and scattering states | qualitative analysis of wavefunctions | qualitative analysis of wavefunctions | Angular momentum: operators | Angular momentum: operators | commutator algebra | commutator algebra | eigenvalues and eigenstates | eigenvalues and eigenstates | spherical harmonics | spherical harmonics | Spin: Stern-Gerlach devices and measurements | Spin: Stern-Gerlach devices and measurements | nuclear magnetic resonance | nuclear magnetic resonance | spin and statistics | spin and statistics | Addition of angular momentum: Clebsch-Gordan series and coefficients | Addition of angular momentum: Clebsch-Gordan series and coefficients | spin systems | spin systems | allotropic forms of hydrogen | allotropic forms of hydrogen | Angular momentum | Angular momentum | Harmonic oscillator | Harmonic oscillator | operator algebra | operator algebra | Spin | Spin | Stern-Gerlach devices and measurements | Stern-Gerlach devices and measurements | central potentials and the radial equation | central potentials and the radial equation | Clebsch-Gordan series and coefficients | Clebsch-Gordan series and coefficients | quantum physics | quantum physics | 8. Quantum mechanics in three-dimensions: central potentials and the radial equation | 8. Quantum mechanics in three-dimensions: central potentials and the radial equation | and allotropic forms of hydrogen | and allotropic forms of hydrogen

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20.320 Analysis of Biomolecular and Cellular Systems (MIT)

Description

This course focuses on computational and experimental analysis of biological systems across a hierarchy of scales, including genetic, molecular, cellular, and cell population levels. The two central themes of the course are modeling of complex dynamic systems and protein design and engineering. Topics include gene sequence analysis, molecular modeling, metabolic and gene regulation networks, signal transduction pathways and cell populations in tissues. Emphasis is placed on experimental methods, quantitative analysis, and computational modeling.

Subjects

biological engineering | kinase | PyMOL | PyRosetta | MATLAB | Michaelis-Menten | bioreactor | bromodomain | protein-ligand interactions | titration analysis | fractional separation | isothermal titration calorimetry | ITC | mass spectrometry | MS | co-immunoprecipitation | Co-IP | Forster resonance energy transfer | FRET | primary ligation assay | PLA | surface plasmon resonance | SPR | enzyme kinetics | kinase engineering | competitive inhibition | epidermal growth factor receptor | mitogen-activated protein kinase | MAPK | genome editing | Imatinib | Gleevec | Glivec | drug delivery | kinetics of molecular processes | dynamics of molecular processes | kinetics of cellular processes | dynamics of cellular processes | intracellular scale | extracellular scale | and cell population scale | biotechnology applications | gene regulation networks | nucleic acid hybridization | signal transduction pathways | cell populations in tissues | cell populations in bioreactors | experimental methods | quantitative analysis | computational modeling

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HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT) HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT)

Description

This team taught, multidisciplinary course covers the fundamentals of magnetic resonance imaging relevant to the conduct and interpretation of human brain mapping studies. The challenges inherent in advancing our knowledge about brain function using fMRI are presented first to put the work in context. The course then provides in depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include fMRI experimental design including block design, event related and exploratory data analysis methods, building and applying statistical mod This team taught, multidisciplinary course covers the fundamentals of magnetic resonance imaging relevant to the conduct and interpretation of human brain mapping studies. The challenges inherent in advancing our knowledge about brain function using fMRI are presented first to put the work in context. The course then provides in depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include fMRI experimental design including block design, event related and exploratory data analysis methods, building and applying statistical mod

Subjects

medical imaging | medical imaging | medical lab | medical lab | medical technology | medical technology | magnetic resonance imaging | magnetic resonance imaging | fMRI | fMRI | signal processing | signal processing | human brain mapping | human brain mapping | function | function | image formation physics | image formation physics | metabolism | metabolism | psychology | psychology | image signals | image signals | parenchymal | parenchymal | cerebrovascular neuroanatomy | cerebrovascular neuroanatomy | functional data analysis | functional data analysis | experimental design | experimental design | statistical models | statistical models | human subjects | human subjects | informed consent | informed consent | institutional review board requirements | institutional review board requirements | safety | safety | medical | medical | brain scan | brain scan

License

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18.03 Differential Equations (MIT) 18.03 Differential Equations (MIT)

Description

Differential Equations are the language in which the laws of nature are expressed. Understanding properties of solutions of differential equations is fundamental to much of contemporary science and engineering. Ordinary differential equations (ODE's) deal with functions of one variable, which can often be thought of as time. Topics include: Solution of first-order ODE's by analytical, graphical and numerical methods; Linear ODE's, especially second order with constant coefficients; Undetermined coefficients and variation of parameters; Sinusoidal and exponential signals: oscillations, damping, resonance; Complex numbers and exponentials; Fourier series, periodic solutions; Delta functions, convolution, and Laplace transform methods; Matrix and first order linear systems: eigenvalues and Differential Equations are the language in which the laws of nature are expressed. Understanding properties of solutions of differential equations is fundamental to much of contemporary science and engineering. Ordinary differential equations (ODE's) deal with functions of one variable, which can often be thought of as time. Topics include: Solution of first-order ODE's by analytical, graphical and numerical methods; Linear ODE's, especially second order with constant coefficients; Undetermined coefficients and variation of parameters; Sinusoidal and exponential signals: oscillations, damping, resonance; Complex numbers and exponentials; Fourier series, periodic solutions; Delta functions, convolution, and Laplace transform methods; Matrix and first order linear systems: eigenvalues and

Subjects

Ordinary Differential Equations | Ordinary Differential Equations | ODE | ODE | modeling physical systems | modeling physical systems | first-order ODE's | first-order ODE's | Linear ODE's | Linear ODE's | second order ODE's | second order ODE's | second order ODE's with constant coefficients | second order ODE's with constant coefficients | Undetermined coefficients | Undetermined coefficients | variation of parameters | variation of parameters | Sinusoidal signals | Sinusoidal signals | exponential signals | exponential signals | oscillations | oscillations | damping | damping | resonance | resonance | Complex numbers and exponentials | Complex numbers and exponentials | Fourier series | Fourier series | periodic solutions | periodic solutions | Delta functions | Delta functions | convolution | convolution | Laplace transform methods | Laplace transform methods | Matrix systems | Matrix systems | first order linear systems | first order linear systems | eigenvalues and eigenvectors | eigenvalues and eigenvectors | Non-linear autonomous systems | Non-linear autonomous systems | critical point analysis | critical point analysis | phase plane diagrams | phase plane diagrams | constant coefficients | constant coefficients | complex numbers | complex numbers | exponentials | exponentials | eigenvalues | eigenvalues | eigenvectors | eigenvectors

License

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6.013 Electromagnetics and Applications (MIT) 6.013 Electromagnetics and Applications (MIT)

Description

This course explores electromagnetic phenomena in modern applications, including wireless communications, circuits, computer interconnects and peripherals, optical fiber links and components, microwave communications and radar, antennas, sensors, micro-electromechanical systems, motors, and power generation and transmission. Fundamentals covered include: quasistatic and dynamic solutions to Maxwell's equations; waves, radiation, and diffraction; coupling to media and structures; guided and unguided waves; resonance; and forces, power, and energy.Acknowledgments The instructors would like to thank Robert Haussman for transcribing into LaTeX the problem set and Quiz 2 solutions. This course explores electromagnetic phenomena in modern applications, including wireless communications, circuits, computer interconnects and peripherals, optical fiber links and components, microwave communications and radar, antennas, sensors, micro-electromechanical systems, motors, and power generation and transmission. Fundamentals covered include: quasistatic and dynamic solutions to Maxwell's equations; waves, radiation, and diffraction; coupling to media and structures; guided and unguided waves; resonance; and forces, power, and energy.Acknowledgments The instructors would like to thank Robert Haussman for transcribing into LaTeX the problem set and Quiz 2 solutions.

Subjects

ESD.013 | ESD.013 | electromagnetics | electromagnetics | applications | applications | wireless communications | wireless communications | circuits | circuits | computer interconnects | computer interconnects | peripherals | peripherals | optical fiber links | optical fiber links | microwave communications | microwave communications | radar | radar | antennas | antennas | sensors | sensors | micro-electromechanical systems | micro-electromechanical systems | power generation | power generation | power transmission | power transmission | quasistatic solutions | quasistatic solutions | dynamic solutions | dynamic solutions | Maxwell | Maxwell | Maxwell's equations | Maxwell's equations | waves | waves | radiation | radiation | diffraction | diffraction | guided waves | guided waves | unguided waves | unguided waves | resonance | resonance | forces | forces | power | power | energy | energy

License

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HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT) HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis (MIT)

Description

This team-taught multidisciplinary course provides information relevant to the conduct and interpretation of human brain mapping studies. It begins with in-depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include: fMRI experimental design including block design, event related and exploratory data analysis methods, and building and applying statistical models for fMRI data; and human subject issues including informed consent, institutional review board requirements and safety in the high field environment. Additional Facul This team-taught multidisciplinary course provides information relevant to the conduct and interpretation of human brain mapping studies. It begins with in-depth coverage of the physics of image formation, mechanisms of image contrast, and the physiological basis for image signals. Parenchymal and cerebrovascular neuroanatomy and application of sophisticated structural analysis algorithms for segmentation and registration of functional data are discussed. Additional topics include: fMRI experimental design including block design, event related and exploratory data analysis methods, and building and applying statistical models for fMRI data; and human subject issues including informed consent, institutional review board requirements and safety in the high field environment. Additional Facul

Subjects

medical imaging | medical imaging | medical lab | medical lab | medical technology | medical technology | magnetic resonance imaging | magnetic resonance imaging | MRI | MRI | fMRI | fMRI | signal processing | signal processing | human brain mapping | human brain mapping | function | function | image formation physics | image formation physics | metabolism | metabolism | psychology | psychology | physiology | physiology | image signals | image signals | image processing | image processing | parenchymal | parenchymal | cerebrovascular neuroanatomy | cerebrovascular neuroanatomy | neurology | neurology | functional data analysis | functional data analysis | experimental design | experimental design | statistical models | statistical models | human subjects | human subjects | informed consent | informed consent | institutional review board requirements | institutional review board requirements | safety | safety | medical | medical | brain scan | brain scan | brain imaging | brain imaging | DTI | DTI | vision | vision

License

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8.421 Atomic and Optical Physics I (MIT)

Description

This is the first of a two-semester subject sequence that provides the foundations for contemporary research in selected areas of atomic and optical physics. Topics covered include the interaction of radiation with atoms: resonance; absorption, stimulated and spontaneous emission; methods of resonance, dressed atom formalism, masers and lasers, cavity quantum electrodynamics; structure of simple atoms, behavior in very strong fields; fundamental tests: time reversal, parity violations, Bell's inequalities; and experimental methods.

Subjects

atom | atomic and optical physics | resonance | resonance frequency | harmonic oscillator | oscillation frequency | magnetic field | electric field | Landau-Zener problem | lamb shift | line broadening | coherence

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