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5.512 Synthetic Organic Chemistry II (MIT) 5.512 Synthetic Organic Chemistry II (MIT)

Description

This course focuses on general methods and strategies for the synthesis of complex organic molecules. Emphasis is on strategies for stereoselective synthesis, including stereocontrolled synthesis of complex acyclic compounds. This course focuses on general methods and strategies for the synthesis of complex organic molecules. Emphasis is on strategies for stereoselective synthesis, including stereocontrolled synthesis of complex acyclic compounds.

Subjects

synthetic organic chemistry | synthetic organic chemistry | synthesis | synthesis | complex organic molecules | complex organic molecules | stereoselective synthesis | stereoselective synthesis | acyclic compounds | acyclic compounds | stereocontrolled synthesis | stereocontrolled synthesis | stereocontrolled alkylation | stereocontrolled alkylation | stereocontrolled conjugate addition | stereocontrolled conjugate addition | carbonyls | carbonyls | aldol reactions | aldol reactions | carbonyl reduction | carbonyl reduction | alkene reduction | alkene reduction | hydroboration | hydroboration | dihydroxylation | dihydroxylation | epoxidation | epoxidation

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7.343 Photosynthesis: Life from Light (MIT) 7.343 Photosynthesis: Life from Light (MIT)

Description

In this course, you will journey through the web of physical, chemical, and biological reactions that collectively constitute photosynthesis. We will begin with light harvesting and follow photons to the sites of primary photochemistry: the photoreaction centers. A molecular-scale view will show in atomic detail how these protein complexes capture and energize electrons. Then we will follow the multiple pathways electrons take as they carry out their work. Consequent reactions, such as the synthesis of ATP and the reduction of CO2 during the synthesis of carbohydrates, will also be discussed in structural detail. Lastly, we will delve into the evolution of these systems and also discuss other photosynthetic strategies, such as light-driven proton pumps and anoxygenic photosynthesis. The co In this course, you will journey through the web of physical, chemical, and biological reactions that collectively constitute photosynthesis. We will begin with light harvesting and follow photons to the sites of primary photochemistry: the photoreaction centers. A molecular-scale view will show in atomic detail how these protein complexes capture and energize electrons. Then we will follow the multiple pathways electrons take as they carry out their work. Consequent reactions, such as the synthesis of ATP and the reduction of CO2 during the synthesis of carbohydrates, will also be discussed in structural detail. Lastly, we will delve into the evolution of these systems and also discuss other photosynthetic strategies, such as light-driven proton pumps and anoxygenic photosynthesis. The co

Subjects

photosynthesis | photosynthesis | life from light | life from light | conversion | conversion | solar energy | solar energy | chemical energy | chemical energy | biogeochemical cycles | biogeochemical cycles | global warming | global warming | physical | physical | chemical and biological reactions | chemical and biological reactions | light harvesting | light harvesting | photochemistry | photochemistry | protein complexes | protein complexes | synthesis of ATP | synthesis of ATP | reduction of CO2 | reduction of CO2 | carbohydrates | carbohydrates | light-driven proton pumps | light-driven proton pumps | anoxygenic photosynthesis | anoxygenic photosynthesis

License

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5.13 Organic Chemistry II (MIT) 5.13 Organic Chemistry II (MIT)

Description

5.13 is an intermediate organic chemistry course that deals primarily with synthesis, structure determination, mechanism, and the relationships between structure and reactivity emphasized. Special topics in organic chemistry are included to illustrate the role of organic chemistry in biological systems, medicine, and in the chemical industry. 5.13 is an intermediate organic chemistry course that deals primarily with synthesis, structure determination, mechanism, and the relationships between structure and reactivity emphasized. Special topics in organic chemistry are included to illustrate the role of organic chemistry in biological systems, medicine, and in the chemical industry.

Subjects

intermediate organic chemistry | intermediate organic chemistry | organic | organic | organic molecules | organic molecules | stereochemistry | stereochemistry | reaction mechanisms | reaction mechanisms | synthesis of organic compounds | synthesis of organic compounds | synthesis | synthesis | structure determination | structure determination | mechanism | mechanism | structure | structure | reactivity | reactivity

License

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5.13 Organic Chemistry II (MIT) 5.13 Organic Chemistry II (MIT)

Description

This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry. This intermediate organic chemistry course focuses on the methods used to identify the structure of organic molecules, advanced principles of organic stereochemistry, organic reaction mechanisms, and methods used for the synthesis of organic compounds. Additional special topics include illustrating the role of organic chemistry in biology, medicine, and industry.

Subjects

intermediate organic chemistry | intermediate organic chemistry | organic molecules | organic molecules | stereochemistry | stereochemistry | reaction mechanisms | reaction mechanisms | synthesis of organic compounds | synthesis of organic compounds | synthesis | synthesis | structure determination | structure determination | mechanism | mechanism | reactivity | reactivity | functional groups | functional groups | NMR | NMR | spectroscopy | spectroscopy | spectrometry | spectrometry | structure elucidation | structure elucidation | infrared spectroscopy | infrared spectroscopy | nuclear magnetic resonance spectroscopy | nuclear magnetic resonance spectroscopy | reactive intermediates | reactive intermediates | carbocations | carbocations | radicals | radicals | aromaticity | aromaticity | conjugated systems | conjugated systems | molecular orbital theory | molecular orbital theory | pericyclic reactions | pericyclic reactions

License

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5.310 Laboratory Chemistry (MIT) 5.310 Laboratory Chemistry (MIT)

Description

Laboratory Chemistry (5.310) introduces experimental chemistry for students requiring a chemistry laboratory who are not majoring in chemistry. Students must have completed general chemistry (5.111) and have completed or be concurrently enrolled in the first semester of organic chemistry (5.12). The course covers principles and applications of chemical laboratory techniques, including preparation and analysis of chemical materials, measurement of pH, gas and liquid chromatography, visible-ultraviolet spectrophotometry, infrared spectroscopy, kinetics, data analysis, and elementary synthesis. NOTE: The Staff for this course would like to acknowledge that the experiments include contributions from past instructors, course textbooks, and others affiliated with course #5.310. Since the Laboratory Chemistry (5.310) introduces experimental chemistry for students requiring a chemistry laboratory who are not majoring in chemistry. Students must have completed general chemistry (5.111) and have completed or be concurrently enrolled in the first semester of organic chemistry (5.12). The course covers principles and applications of chemical laboratory techniques, including preparation and analysis of chemical materials, measurement of pH, gas and liquid chromatography, visible-ultraviolet spectrophotometry, infrared spectroscopy, kinetics, data analysis, and elementary synthesis. NOTE: The Staff for this course would like to acknowledge that the experiments include contributions from past instructors, course textbooks, and others affiliated with course #5.310. Since the

Subjects

lab | lab | chemistry | chemistry | laboratory | laboratory | experiment | experiment | pH | pH | gas chromatography | gas chromatography | liquid chromatography | liquid chromatography | visible-ultraviolet spectrophotometry | visible-ultraviolet spectrophotometry | infrared spectroscopy | infrared spectroscopy | kinetics | kinetics | data analysis | data analysis | elementary synthesis | elementary synthesis | amino acid | amino acid | ferrocene | ferrocene | essential oil | essential oil | potentiometric titration | potentiometric titration | techniques | techniques | measurement | measurement | materials | materials | data | data | analysis | analysis | elementary | elementary | synthesis | synthesis | amino | amino | acid | acid | essential | essential | oil | oil | gas | gas | chromatography | chromatography | infrared | infrared | spectroscopy | spectroscopy | liquid | liquid | potentiometric | potentiometric | titration | titration | visible | visible | ultraviolet | ultraviolet | spectrophotometry | spectrophotometry

License

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7.06 Cell Biology (MIT) 7.06 Cell Biology (MIT)

Description

This course deals with the biology of cells of higher organisms: The structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis. This course deals with the biology of cells of higher organisms: The structure, function, and biosynthesis of cellular membranes and organelles; cell growth and oncogenic transformation; transport, receptors, and cell signaling; the cytoskeleton, the extracellular matrix, and cell movements; chromatin structure and RNA synthesis.

Subjects

Biology | Biology | cells | cells | organisms | organisms | biosynthesis | biosynthesis | cellular membranes | cellular membranes | organelles | organelles | cell growth | cell growth | oncogenic transformation | oncogenic transformation | transport | transport | receptors | receptors | cell signaling | cell signaling | cytoskeleton | cytoskeleton | extracellular matrix | extracellular matrix | matrix | matrix | cell movements | cell movements | chromatin | chromatin | RNA | RNA | RNA synthesis | RNA synthesis

License

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MAS.632 Conversational Computer Systems (MIT) MAS.632 Conversational Computer Systems (MIT)

Description

This class explores interaction with mobile computing systems and telephones by voice, including speech synthesis, recognition, digital recording, and browsing recorded speech. Emphasis on human interface design issues and interaction techniques appropriate for cognitive requirements of speech. Topics include human speech production and perception, speech recognition and text-to-speech algorithms, telephone networks, and spatial and time-compressed listening. Extensive reading from current research literature. This class explores interaction with mobile computing systems and telephones by voice, including speech synthesis, recognition, digital recording, and browsing recorded speech. Emphasis on human interface design issues and interaction techniques appropriate for cognitive requirements of speech. Topics include human speech production and perception, speech recognition and text-to-speech algorithms, telephone networks, and spatial and time-compressed listening. Extensive reading from current research literature.

Subjects

digital voice | digital voice | voice synthesis | voice synthesis | speech synthesis | speech synthesis | digital speech | digital speech | audio | audio | coding | coding | noise | noise | comprehension | comprehension | audio browsing | audio browsing | voice messaging | voice messaging | voice recognition | voice recognition | call center | call center | voice response | voice response | computer voice | computer voice | computer speech | computer speech | telephony | telephony | mobile applications | mobile applications | voicemail | voicemail

License

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5.512 Synthetic Organic Chemistry II (MIT)

Description

This course focuses on general methods and strategies for the synthesis of complex organic molecules. Emphasis is on strategies for stereoselective synthesis, including stereocontrolled synthesis of complex acyclic compounds.

Subjects

synthetic organic chemistry | synthesis | complex organic molecules | stereoselective synthesis | acyclic compounds | stereocontrolled synthesis | stereocontrolled alkylation | stereocontrolled conjugate addition | carbonyls | aldol reactions | carbonyl reduction | alkene reduction | hydroboration | dihydroxylation | epoxidation

License

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7.343 Photosynthesis: Life from Light (MIT)

Description

In this course, you will journey through the web of physical, chemical, and biological reactions that collectively constitute photosynthesis. We will begin with light harvesting and follow photons to the sites of primary photochemistry: the photoreaction centers. A molecular-scale view will show in atomic detail how these protein complexes capture and energize electrons. Then we will follow the multiple pathways electrons take as they carry out their work. Consequent reactions, such as the synthesis of ATP and the reduction of CO2 during the synthesis of carbohydrates, will also be discussed in structural detail. Lastly, we will delve into the evolution of these systems and also discuss other photosynthetic strategies, such as light-driven proton pumps and anoxygenic photosynthesis. The co

Subjects

photosynthesis | life from light | conversion | solar energy | chemical energy | biogeochemical cycles | global warming | physical | chemical and biological reactions | light harvesting | photochemistry | protein complexes | synthesis of ATP | reduction of CO2 | carbohydrates | light-driven proton pumps | anoxygenic photosynthesis

License

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7.343 Photosynthesis: Life from Light (MIT)

Description

In this course, you will journey through the web of physical, chemical, and biological reactions that collectively constitute photosynthesis. We will begin with light harvesting and follow photons to the sites of primary photochemistry: the photoreaction centers. A molecular-scale view will show in atomic detail how these protein complexes capture and energize electrons. Then we will follow the multiple pathways electrons take as they carry out their work. Consequent reactions, such as the synthesis of ATP and the reduction of CO2 during the synthesis of carbohydrates, will also be discussed in structural detail. Lastly, we will delve into the evolution of these systems and also discuss other photosynthetic strategies, such as light-driven proton pumps and anoxygenic photosynthesis. The co

Subjects

photosynthesis | life from light | conversion | solar energy | chemical energy | biogeochemical cycles | global warming | physical | chemical and biological reactions | light harvesting | photochemistry | protein complexes | synthesis of ATP | reduction of CO2 | carbohydrates | light-driven proton pumps | anoxygenic photosynthesis

License

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5.512 Synthetic Organic Chemistry II (MIT)

Description

This course focuses on general methods and strategies for the synthesis of complex organic molecules. Emphasis is on strategies for stereoselective synthesis, including stereocontrolled synthesis of complex acyclic compounds.

Subjects

synthetic organic chemistry | synthesis | complex organic molecules | stereoselective synthesis | acyclic compounds | stereocontrolled synthesis | stereocontrolled alkylation | stereocontrolled conjugate addition | carbonyls | aldol reactions | carbonyl reduction | alkene reduction | hydroboration | dihydroxylation | epoxidation

License

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12.158 Molecular Biogeochemistry (MIT) 12.158 Molecular Biogeochemistry (MIT)

Description

This course covers all aspects of molecular biosignatures, such as their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record. Students analyze in depth the recent literature on chemical fossils. Lectures provide background on the subject matter. Basic knowledge of organic chemistry required. Students taking graduate version complete additional assignments. This course covers all aspects of molecular biosignatures, such as their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record. Students analyze in depth the recent literature on chemical fossils. Lectures provide background on the subject matter. Basic knowledge of organic chemistry required. Students taking graduate version complete additional assignments.

Subjects

molecular biogeochemistry | molecular biogeochemistry | biosynthesis | biosynthesis | phylogenetic origins | phylogenetic origins | acetogenic lipids | acetogenic lipids | acylic isoprenoids | acylic isoprenoids | molecular biosugnatures | molecular biosugnatures | steroids | steroids | mass spectrometry | mass spectrometry

License

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12.458 Molecular Biogeochemistry (MIT) 12.458 Molecular Biogeochemistry (MIT)

Description

This course evaluates and discusses the formation and diagnostic structural properties of organic compounds with particular emphasis on those molecules which form chemical fossils. The course is structured around the biosynthetic and phylogenetic origins of recalcitrant hydrocarbons. This course evaluates and discusses the formation and diagnostic structural properties of organic compounds with particular emphasis on those molecules which form chemical fossils. The course is structured around the biosynthetic and phylogenetic origins of recalcitrant hydrocarbons.

Subjects

molecular biogeochemistry | molecular biogeochemistry | biosynthesis | biosynthesis | phylogenetic origins | phylogenetic origins | acetogenic lipids | acetogenic lipids | acylic isoprenoids | acylic isoprenoids | molecular biosugnatures | molecular biosugnatures | steroids | steroids | mass spectrometry | mass spectrometry

License

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12.458 Molecular Biogeochemistry (MIT) 12.458 Molecular Biogeochemistry (MIT)

Description

This course covers all aspects of molecular biosignatures from their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record. This course covers all aspects of molecular biosignatures from their pathways of lipid biosynthesis, the distribution patterns of lipid biosynthetic pathways with regard to phylogeny and physiology, isotopic contents, occurrence in modern organisms and environments, diagenetic pathways, analytical techniques and the occurrence of molecular fossils through the geological record.

Subjects

molecular biogeochemistry | molecular biogeochemistry | biosynthesis | biosynthesis | phylogenetic associations | phylogenetic associations | bacteria | bacteria | eukarya | eukarya | sterochemical modifications | sterochemical modifications

License

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7.89 Topics in Computational and Systems Biology (MIT) 7.89 Topics in Computational and Systems Biology (MIT)

Description

This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments. The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB PhD program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology. Acknowledgments In addition to the staff listed on this page, the followi This is a seminar based on research literature. Papers covered are selected to illustrate important problems and approaches in the field of computational and systems biology, and provide students a framework from which to evaluate new developments. The MIT Initiative in Computational and Systems Biology (CSBi) is a campus-wide research and education program that links biology, engineering, and computer science in a multidisciplinary approach to the systematic analysis and modeling of complex biological phenomena. This course is one of a series of core subjects offered through the CSB PhD program, for students with an interest in interdisciplinary training and research in the area of computational and systems biology. Acknowledgments In addition to the staff listed on this page, the followi

Subjects

computational | computational | systems | systems | biology | biology | seminar | seminar | literature review | literature review | statistics | statistics | developmental | developmental | biochemistry | biochemistry | genetics | genetics | physics | physics | genomics | genomics | signal transduction | signal transduction | regulation | regulation | medicine | medicine | kinetics | kinetics | protein structure | protein structure | devices | devices | synthesis | synthesis | networks | networks | mapping | mapping

License

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MAS.110 Fundamentals of Computational Media Design (MIT) MAS.110 Fundamentals of Computational Media Design (MIT)

Description

This class introduces principles of analysis and synthesis in the computational medium. Expressive examples that illustrate the intersection of computation with the traditional arts are developed on a weekly basis. Hands-on design exercises are continually framed and examined in the larger context of contemporary digital art. This class introduces principles of analysis and synthesis in the computational medium. Expressive examples that illustrate the intersection of computation with the traditional arts are developed on a weekly basis. Hands-on design exercises are continually framed and examined in the larger context of contemporary digital art.

Subjects

analysis | analysis | synthesis | synthesis | computational media | computational media | computational and traditional arts | computational and traditional arts | design | design | programming | programming | javascript | javascript | contemporary digital art | contemporary digital art | machine age | machine age | media design | media design | analog vs digital art | analog vs digital art | graphic design | graphic design | web design | web design | photography | photography | storytelling | storytelling | modern art | modern art | computation | computation | arts | arts | design exercises | design exercises | studio | studio | analog art | analog art

License

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9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT) 9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT)

Description

This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. The class focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); it also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control. This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. The class focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); it also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.

Subjects

neurotransmission | neurotransmission | nerve terminals | nerve terminals | monoamine transmitters | monoamine transmitters | acetylcholine | acetylcholine | serotonin | serotonin | dopamine | dopamine | norepinephrine | norepinephrine | amino acid and peptide transmitters | amino acid and peptide transmitters | neuromodulators | neuromodulators | adenosine | adenosine | neurotransmitter synthesis | neurotransmitter synthesis | release | release | inactivation | inactivation | receptor-mediated | receptor-mediated | second-messenger | second-messenger | neurotransmitter | neurotransmitter | antidepressant | antidepressant | brain lipid | brain lipid | blood brain barrier | blood brain barrier | parkinson's disease | parkinson's disease | seratonin | seratonin | depression | depression | glutamate | glutamate | aspartate | aspartate | NDMA | NDMA | drug | drug | drug discovery | drug discovery | pharmaceutical | pharmaceutical | signaling pathway | signaling pathway | receptor | receptor | spinal cord | spinal cord | marijuana | marijuana | adensosine | adensosine | histamine | histamine

License

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BE.462J Molecular Principles of Biomaterials (MIT) BE.462J Molecular Principles of Biomaterials (MIT)

Description

Analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, biosensors, and cell-guiding surfaces.Technical RequirementsMicrosoft® Excel software is recommended for viewing the .xls files found on this course site. Free Microsoft® Excel viewer software can also be used to view the .xls files.Microsoft® is a registered trademark or trademark of Microsoft Corporation in the U.S Analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, biosensors, and cell-guiding surfaces.Technical RequirementsMicrosoft® Excel software is recommended for viewing the .xls files found on this course site. Free Microsoft® Excel viewer software can also be used to view the .xls files.Microsoft® is a registered trademark or trademark of Microsoft Corporation in the U.S

Subjects

Analysis | Analysis | design | design | molecular scale | molecular scale | biological systems | biological systems | biotechnology | biotechnology | biomedical engineering | biomedical engineering | molecular interactions | molecular interactions | synthetic molecules | synthetic molecules | synthesis | synthesis | processing approaches | processing approaches | cell functions | cell functions | materials science | materials science | tissue engineering | tissue engineering | drug delivery | drug delivery | biosensors | biosensors | cell-guiding surfaces | cell-guiding surfaces | 3.962J | 3.962J | BE.462 | BE.462 | 3.962 | 3.962

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5.33 Advanced Chemical Experimentation and Instrumentation (MIT) 5.33 Advanced Chemical Experimentation and Instrumentation (MIT)

Description

5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.WARNING NOTICE:The experiments described in these materials are potentially hazardous andrequire a high level of safety training, special facilities and equipment, and supervision by appropriateindividuals. You bear the sole responsibility, liability, and risk for the implementation of such safetyprocedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementationof any of the material presented.Legal Notice<br clear="all&gt;&lt;br clear=" all="all" /> 5.33 focuses on advanced experimentation, with particular emphasis on chemical synthesis and the fundamentals of quantum chemistry, illustrated through molecular spectroscopy. The written and oral presentation of experimental results is also emphasized in the course.WARNING NOTICE:The experiments described in these materials are potentially hazardous andrequire a high level of safety training, special facilities and equipment, and supervision by appropriateindividuals. You bear the sole responsibility, liability, and risk for the implementation of such safetyprocedures and measures. MIT shall have no responsibility, liability, or risk for the content or implementationof any of the material presented.Legal Notice<br clear="all&gt;&lt;br clear=" all="all" />

Subjects

advanced chemical experimentation | advanced chemical experimentation | Instrumentation | Instrumentation | experiment | experiment | chemistry | chemistry | laboratory | laboratory | integrated chemisty laboratory | integrated chemisty laboratory | chemical synthesis | chemical synthesis | quantum chemistry | quantum chemistry | molecular spectroscopy | molecular spectroscopy

License

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9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT) 9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT)

Description

Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control. An additional project is required for graduate credit. Considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. Focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control. An additional project is required for graduate credit.

Subjects

neurotransmission | neurotransmission | nerve terminals | nerve terminals | monoamine transmitters | monoamine transmitters | acetylcholine | acetylcholine | serotonin | serotonin | dopamine | dopamine | norepinephrine | norepinephrine | amino acid and peptide transmitters | amino acid and peptide transmitters | neuromodulators | neuromodulators | adenosine | adenosine | neurotransmitter synthesis | neurotransmitter synthesis | release | release | inactivation | inactivation | receptor-mediated | receptor-mediated | second-messenger | second-messenger

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20.462J Molecular Principles of Biomaterials (BE.462J) (MIT) 20.462J Molecular Principles of Biomaterials (BE.462J) (MIT)

Description

Analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, biosensors, and cell-guiding surfaces.Technical RequirementsMicrosoft&#174; Excel software&#160;is recommended for viewing the .xls files found on this course site. Free&#160;Microsoft&#174; Excel viewer software&#160;can also be used to view the .xls files.Microsoft&#174; is a registered trademark or trademark of Microsoft Corporation in the U.S Analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, biosensors, and cell-guiding surfaces.Technical RequirementsMicrosoft&#174; Excel software&#160;is recommended for viewing the .xls files found on this course site. Free&#160;Microsoft&#174; Excel viewer software&#160;can also be used to view the .xls files.Microsoft&#174; is a registered trademark or trademark of Microsoft Corporation in the U.S

Subjects

Analysis | Analysis | design | design | molecular scale | molecular scale | biological systems | biological systems | biotechnology | biotechnology | biomedical engineering | biomedical engineering | molecular interactions | molecular interactions | synthetic molecules | synthetic molecules | synthesis | synthesis | processing approaches | processing approaches | cell functions | cell functions | materials science | materials science | tissue engineering | tissue engineering | drug delivery | drug delivery | biosensors | biosensors | cell-guiding surfaces | cell-guiding surfaces | BE.462J | BE.462J | BE.462 | BE.462 | 3.962 | 3.962

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7.013 Introductory Biology (MIT) 7.013 Introductory Biology (MIT)

Description

The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.7.013 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer), The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material.7.013 focuses on the application of the fundamental principles toward an understanding of human biology. Topics include genetics, cell biology, molecular biology, disease (infectious agents, inherited diseases and cancer),

Subjects

biology | biology | biochemistry | biochemistry | genetics | genetics | molecular biology | molecular biology | recombinant DNA | recombinant DNA | cell cycle | cell cycle | cell signaling | cell signaling | cloning | cloning | stem cells | stem cells | cancer | cancer | immunology | immunology | virology | virology | genomics | genomics | molecular medicine | molecular medicine | DNA | DNA | RNA | RNA | proteins | proteins | replication | replication | transcription | transcription | mRNA | mRNA | translation | translation | ribosome | ribosome | nervous system | nervous system | amino acids | amino acids | polypeptide chain | polypeptide chain | cell biology | cell biology | neurobiology | neurobiology | gene regulation | gene regulation | protein structure | protein structure | protein synthesis | protein synthesis | gene structure | gene structure | PCR | PCR | polymerase chain reaction | polymerase chain reaction | protein localization | protein localization | endoplasmic reticulum | endoplasmic reticulum | human biology | human biology | inherited diseases | inherited diseases | developmental biology | developmental biology | evolution | evolution | human genetics | human genetics | human diseases | human diseases | infectious agents | infectious agents | infectious diseases | infectious diseases

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8.282J Introduction to Astronomy (MIT) 8.282J Introduction to Astronomy (MIT)

Description

Introduction to Astronomy provides a quantitative introduction to physics of the solar system, stars, interstellar medium, the galaxy, and universe, as determined from a variety of astronomical observations and models.Topics include: planets, planet formation; stars, the Sun, "normal" stars, star formation; stellar evolution, supernovae, compact objects (white dwarfs, neutron stars, and black holes), plusars, binary X-ray sources; star clusters, globular and open clusters; interstellar medium, gas, dust, magnetic fields, cosmic rays; distance ladder; galaxies, normal and active galaxies, jets; gravitational lensing; large scaling structure; Newtonian cosmology, dynamical expansion and thermal history of the Universe; cosmic microwave background radiation; big-bang nucleosynthesis Introduction to Astronomy provides a quantitative introduction to physics of the solar system, stars, interstellar medium, the galaxy, and universe, as determined from a variety of astronomical observations and models.Topics include: planets, planet formation; stars, the Sun, "normal" stars, star formation; stellar evolution, supernovae, compact objects (white dwarfs, neutron stars, and black holes), plusars, binary X-ray sources; star clusters, globular and open clusters; interstellar medium, gas, dust, magnetic fields, cosmic rays; distance ladder; galaxies, normal and active galaxies, jets; gravitational lensing; large scaling structure; Newtonian cosmology, dynamical expansion and thermal history of the Universe; cosmic microwave background radiation; big-bang nucleosynthesis

Subjects

solar system; stars; interstellar medium; the Galaxy; the Universe; planets; planet formation; star formation; stellar evolution; supernovae; compact objects; white dwarfs; neutron stars; black holes; plusars | binary X-ray sources; star clusters; globular and open clusters; interstellar medium | gas | dust | magnetic fields | cosmic rays; distance ladder; | solar system; stars; interstellar medium; the Galaxy; the Universe; planets; planet formation; star formation; stellar evolution; supernovae; compact objects; white dwarfs; neutron stars; black holes; plusars | binary X-ray sources; star clusters; globular and open clusters; interstellar medium | gas | dust | magnetic fields | cosmic rays; distance ladder; | solar system | solar system | stars | stars | interstellar medium | interstellar medium | the Galaxy | the Galaxy | the Universe | the Universe | planets | planets | planet formation | planet formation | star formation | star formation | stellar evolution | stellar evolution | supernovae | supernovae | compact objects | compact objects | white dwarfs | white dwarfs | neutron stars | neutron stars | black holes | black holes | plusars | binary X-ray sources | plusars | binary X-ray sources | star clusters | star clusters | globular and open clusters | globular and open clusters | interstellar medium | gas | dust | magnetic fields | cosmic rays | interstellar medium | gas | dust | magnetic fields | cosmic rays | distance ladder | distance ladder | galaxies | normal and active galaxies | jets | galaxies | normal and active galaxies | jets | gravitational lensing | gravitational lensing | large scaling structure | large scaling structure | Newtonian cosmology | dynamical expansion and thermal history of the Universe | Newtonian cosmology | dynamical expansion and thermal history of the Universe | cosmic microwave background radiation | cosmic microwave background radiation | big-bang nucleosynthesis | big-bang nucleosynthesis | pulsars | pulsars | binary X-ray sources | binary X-ray sources | gas | gas | dust | dust | magnetic fields | magnetic fields | cosmic rays | cosmic rays | galaxy | galaxy | universe | universe | astrophysics | astrophysics | Sun | Sun | supernova | supernova | globular clusters | globular clusters | open clusters | open clusters | jets | jets | Newtonian cosmology | Newtonian cosmology | dynamical expansion | dynamical expansion | thermal history | thermal history | normal galaxies | normal galaxies | active galaxies | active galaxies | Greek astronomy | Greek astronomy | physics | physics | Copernicus | Copernicus | Tycho | Tycho | Kepler | Kepler | Galileo | Galileo | classical mechanics | classical mechanics | circular orbits | circular orbits | full kepler orbit problem | full kepler orbit problem | electromagnetic radiation | electromagnetic radiation | matter | matter | telescopes | telescopes | detectors | detectors | 8.282 | 8.282 | 12.402 | 12.402

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7.012 Introduction to Biology (MIT) 7.012 Introduction to Biology (MIT)

Description

All three courses: 7.012, 7.013 and 7.014 cover the same core material which includes: the fundamental principles of biochemistry as they apply to introductory biology, genetics, molecular biology, basic recombinant DNA technology, and gene regulation.In addition, each version of the subject has its own distinctive material, described below. Note: All three versions require a familiarity with some basic chemistry. For details, see the Chemistry Self-evaluation.7.012 focuses on cell biology, immunology, neurobiology, and includes an exploration into current research in cancer, genomics, and molecular medicine.&#160;7.013 focuses on the application of the fundamental principles toward an understanding of cells, human genetics and diseases, infectious agents, cancer, immunology, molecular All three courses: 7.012, 7.013 and 7.014 cover the same core material which includes: the fundamental principles of biochemistry as they apply to introductory biology, genetics, molecular biology, basic recombinant DNA technology, and gene regulation.In addition, each version of the subject has its own distinctive material, described below. Note: All three versions require a familiarity with some basic chemistry. For details, see the Chemistry Self-evaluation.7.012 focuses on cell biology, immunology, neurobiology, and includes an exploration into current research in cancer, genomics, and molecular medicine.&#160;7.013 focuses on the application of the fundamental principles toward an understanding of cells, human genetics and diseases, infectious agents, cancer, immunology, molecular

Subjects

amino acids | amino acids | biochemistry | biochemistry | cancer | cancer | cell biology | cell biology | cell cycle | cell cycle | cell signaling | cell signaling | cloning | cloning | DNA | DNA | endoplasmic reticulum | endoplasmic reticulum | gene regulation | gene regulation | gene structure | gene structure | genetics | genetics | genomics | genomics | immunology | immunology | molecular biology | molecular biology | molecular medicine | molecular medicine | mRNA | mRNA | nervous system | nervous system | neurobiology | neurobiology | PCR | PCR | polymerase chain reaction | polymerase chain reaction | polypeptide chain | polypeptide chain | protein localization | protein localization | protein structure | protein structure | protein synthesis | protein synthesis | proteins | proteins | recombinant DNA | recombinant DNA | replication | replication | ribosome | ribosome | RNA | RNA | stem cells | stem cells | transcription | transcription | translation | translation | virology | virology | biology | biology

License

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7.01SC Fundamentals of Biology (MIT) 7.01SC Fundamentals of Biology (MIT)

Description

Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality. Fundamentals of Biology focuses on the basic principles of biochemistry, molecular biology, genetics, and recombinant DNA. These principles are necessary to understanding the basic mechanisms of life and anchor the biological knowledge that is required to understand many of the challenges in everyday life, from human health and disease to loss of biodiversity and environmental quality.

Subjects

amino acids | amino acids | carboxyl group | carboxyl group | amino group | amino group | side chains | side chains | polar | polar | hydrophobic | hydrophobic | primary structure | primary structure | secondary structure | secondary structure | tertiary structure | tertiary structure | quaternary structure | quaternary structure | x-ray crystallography | x-ray crystallography | alpha helix | alpha helix | beta sheet | beta sheet | ionic bond | ionic bond | non-polar bond | non-polar bond | van der Waals interactions | van der Waals interactions | proton gradient | proton gradient | cyclic photophosphorylation | cyclic photophosphorylation | sunlight | sunlight | ATP | ATP | chlorophyll | chlorophyll | chlorophyll a | chlorophyll a | electrons | electrons | hydrogen sulfide | hydrogen sulfide | biosynthesis | biosynthesis | non-cyclic photophosphorylation | non-cyclic photophosphorylation | photosystem II | photosystem II | photosystem I | photosystem I | cyanobacteria | cyanobacteria | chloroplast | chloroplast | stroma | stroma | thylakoid membrane | thylakoid membrane | Genetics | Genetics | Mendel | Mendel | Mendel's Laws | Mendel's Laws | cloning | cloning | restriction enzymes | restriction enzymes | vector | vector | insert DNA | insert DNA | ligase | ligase | library | library | E.Coli | E.Coli | phosphatase | phosphatase | yeast | yeast | transformation | transformation | ARG1 gene | ARG1 gene | ARG1 mutant yeast | ARG1 mutant yeast | yeast wild-type | yeast wild-type | cloning by complementation | cloning by complementation | Human Beta Globin gene | Human Beta Globin gene | protein tetramer | protein tetramer | vectors | vectors | antibodies | antibodies | human promoter | human promoter | splicing | splicing | mRNA | mRNA | cDNA | cDNA | reverse transcriptase | reverse transcriptase | plasmid | plasmid | electrophoresis | electrophoresis | DNA sequencing | DNA sequencing | primer | primer | template | template | capillary tube | capillary tube | laser detector | laser detector | human genome project | human genome project | recombinant DNA | recombinant DNA | clone | clone | primer walking | primer walking | subcloning | subcloning | computer assembly | computer assembly | shotgun sequencing | shotgun sequencing | open reading frame | open reading frame | databases | databases | polymerase chain reaction (PCR) | polymerase chain reaction (PCR) | polymerase | polymerase | nucleotides | nucleotides | Thermus aquaticus | Thermus aquaticus | Taq polymerase | Taq polymerase | thermocycler | thermocycler | resequencing | resequencing | in vitro fertilization | in vitro fertilization | pre-implantation diagnostics | pre-implantation diagnostics | forensics | forensics | genetic engineering | genetic engineering | DNA sequences | DNA sequences | therapeutic proteins | therapeutic proteins | E. coli | E. coli | disease-causing mutations | disease-causing mutations | cleavage of DNA | cleavage of DNA | bacterial transformation | bacterial transformation | recombinant DNA revolution | recombinant DNA revolution | biotechnology industry | biotechnology industry | Robert Swanson | Robert Swanson | toxin gene | toxin gene | pathogenic bacterium | pathogenic bacterium | biomedical research | biomedical research | S. Pyogenes | S. Pyogenes | origin of replication | origin of replication

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