Description

This course focuses on the mechanisms by which the amino acid sequence of polypeptide chains (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects. This course focuses on the mechanisms by which the amino acid sequence of polypeptide chains (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects.

Subjects

amino acid sequence | amino acid sequence | polypeptide chains | polypeptide chains | sequence determinants | sequence determinants | folding | folding | synthesized polypeptide chains within cells | synthesized polypeptide chains within cells | unfolding and refolding of proteins in vitro | unfolding and refolding of proteins in vitro | folding intermediates aggregation | folding intermediates aggregation | competing off-pathway reactions | competing off-pathway reactions | chaperonins | chaperonins | isomerases | isomerases | helper proteins | helper proteins | protein recovery problems | protein recovery problems | biotechnology industry | biotechnology industry | protein folding defects | protein folding defects | 3-D conformation | 3-D conformation | globular proteins | globular proteins | fibrous proteins | fibrous proteins | kinetics | kinetics | in vitro refolding | in vitro refolding | pathways | pathways | in vivo folding | in vivo folding | synthesized proteins | synthesized proteins | aggregation | aggregation | protein misfolding | protein misfolding | human disease | human disease | protein folding | protein folding | genome sequences | genome sequences | 7.88 | 7.88 | 5.48 | 5.48 | 7.24 | 7.24 | 10.543 | 10.543

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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14.462 is the second semester of the second-year Ph.D. macroeconomics sequence. The course is intended to introduce the students, not only to particular areas of current research, but also to some very useful analytical tools. It covers a selection of topics that varies from year to year. Recent topics include: Growth and Fluctuations Heterogeneity and Incomplete Markets Optimal Fiscal Policy Time Inconsistency Reputation Coordination Games and Macroeconomic Complementarities Information 14.462 is the second semester of the second-year Ph.D. macroeconomics sequence. The course is intended to introduce the students, not only to particular areas of current research, but also to some very useful analytical tools. It covers a selection of topics that varies from year to year. Recent topics include: Growth and Fluctuations Heterogeneity and Incomplete Markets Optimal Fiscal Policy Time Inconsistency Reputation Coordination Games and Macroeconomic Complementarities Information

Subjects

macroeconomics research; analytical tools; analysis; endogenous growth; coordintation; incomplete markets; technolgy; distribution; employment; intellectual property rights; bounded rationality; demographics; complementarities; amplification; recursive equilibria; uncertainty; morris; shin; global games; policy; price; aggregation; social learning; dynamic adjustment; business cycle; heterogeneous agents; savings; utility; aiyagari; steady state; krusell; smith; idiosyncratic investment risk | macroeconomics research; analytical tools; analysis; endogenous growth; coordintation; incomplete markets; technolgy; distribution; employment; intellectual property rights; bounded rationality; demographics; complementarities; amplification; recursive equilibria; uncertainty; morris; shin; global games; policy; price; aggregation; social learning; dynamic adjustment; business cycle; heterogeneous agents; savings; utility; aiyagari; steady state; krusell; smith; idiosyncratic investment risk | macroeconomics research | macroeconomics research | analytical tools | analytical tools | analysis | analysis | endogenous growth | endogenous growth | coordintation | coordintation | incomplete markets | incomplete markets | technolgy | technolgy | distribution | distribution | employment | employment | intellectual property rights | intellectual property rights | bounded rationality | bounded rationality | demographics | demographics | complementarities | complementarities | amplification | amplification | recursive equilibria | recursive equilibria | uncertainty | uncertainty | morris | morris | shin | shin | global games | global games | policy | policy | price | price | aggregation | aggregation | social learning | social learning | dynamic adjustment | dynamic adjustment | business cycle | business cycle | heterogeneous agents | heterogeneous agents | savings | savings | utility | utility | aiyagari | aiyagari | steady state | steady state | krusell | krusell | smith | smith | idiosyncratic investment risk | idiosyncratic investment risk | growth | growth | fluctuations | fluctuations | heterogeneity | heterogeneity | optimal fiscal policy | optimal fiscal policy | time inconsistency | time inconsistency | reputation | reputation | information | information | coordination games | coordination games

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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This course covers amino acid sequence control of protein folding, misfolding, amyloid polymerization and aggregation. Readings and discussions address topics such as chaperone structure and function, folding and assembly of fibrous proteins, and pathologies associated with protein misfolding and aggregation in Alzheimer's, Parkinson's, Huntington's and other protein deposition diseases. Students are required to write and present a research paper. This course covers amino acid sequence control of protein folding, misfolding, amyloid polymerization and aggregation. Readings and discussions address topics such as chaperone structure and function, folding and assembly of fibrous proteins, and pathologies associated with protein misfolding and aggregation in Alzheimer's, Parkinson's, Huntington's and other protein deposition diseases. Students are required to write and present a research paper.

Subjects

protein folding | protein folding | misfolding | misfolding | aggregation | aggregation | protein structures | protein structures | folding intermediates | folding intermediates | off-pathway aggregation | off-pathway aggregation | amyloid formation | amyloid formation | Key chaperones | Key chaperones | chaperonins | chaperonins | human protein deposition diseases | human protein deposition diseases | Alzheimer’s disease | Alzheimer’s disease | Parkinson’s disease | Parkinson’s disease | Huntington’s disease | Huntington’s disease | amyloids | amyloids | prions | prions | amino acid sequence | amino acid sequence | amyloid polymerization | amyloid polymerization | chaperone structure and function | chaperone structure and function | folding and assembly of fibrous proteins | folding and assembly of fibrous proteins

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. The instructor for this course, Dr. Kosinski-Collins, is a member of the HHMI Education Group. Maintenance of the complex three-dimensional structure adopted by a protein in the cell is vital for function. Oftentimes, as a consequence of environmental stress, genetic mutation, and/or infection, the folded structure of a protein gets altered and multiple proteins stick and fall out of solution in a process known as aggregation. In many protein aggregation diseases, incorrectly folded proteins self-associate, for This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. The instructor for this course, Dr. Kosinski-Collins, is a member of the HHMI Education Group. Maintenance of the complex three-dimensional structure adopted by a protein in the cell is vital for function. Oftentimes, as a consequence of environmental stress, genetic mutation, and/or infection, the folded structure of a protein gets altered and multiple proteins stick and fall out of solution in a process known as aggregation. In many protein aggregation diseases, incorrectly folded proteins self-associate, for

Subjects

protein folding | protein folding | misfolded proteins | misfolded proteins | Mad Cow | Mad Cow | Creutzfedt-Jakob Disease | Creutzfedt-Jakob Disease | Alzheimer's Disease | Alzheimer's Disease | Huntington's Disease | Huntington's Disease | protein aggregation | protein aggregation | self-associate | self-associate | cell death | cell death | dementia | dementia | prions | prions | bovine spongiform encephalopathy | bovine spongiform encephalopathy | kuru | kuru | scrapie | scrapie | protein structure | protein structure | amyloid protein | amyloid protein | amyloidosis | amyloidosis | polyglutamine repeats | polyglutamine repeats | fibrils | fibrils

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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This half-semester course provides an introduction to microeconomic theory designed to meet the needs of students in the economics Ph.D. program. Some parts of the course are designed to teach material that all graduate students should know. Others are used to introduce methodologies. Topics include consumer and producer theory, markets and competition, general equilibrium, and tools of comparative statics and their application to price theory. Some topics of recent interest may also be covered. This half-semester course provides an introduction to microeconomic theory designed to meet the needs of students in the economics Ph.D. program. Some parts of the course are designed to teach material that all graduate students should know. Others are used to introduce methodologies. Topics include consumer and producer theory, markets and competition, general equilibrium, and tools of comparative statics and their application to price theory. Some topics of recent interest may also be covered.

Subjects

microeconomic theory | microeconomic theory | demand theory | demand theory | producer theory; partial equilibrium | producer theory; partial equilibrium | competitive markets | competitive markets | general equilibrium | general equilibrium | externalities | externalities | Afriat's theorem | Afriat's theorem | pricing | pricing | robust comparative statics | robust comparative statics | utility theory | utility theory | properties of preferences | properties of preferences | choice as primitive | choice as primitive | revealed preference | revealed preference | classical demand theory | classical demand theory | Kuhn-Tucker necessary conditions | Kuhn-Tucker necessary conditions | implications of Walras?s law | implications of Walras?s law | indirect utility functions | indirect utility functions | theorem of the maximum (Berge?s theorem) | theorem of the maximum (Berge?s theorem) | expenditure minimization problem | expenditure minimization problem | Hicksian demands | Hicksian demands | compensated law of demand | compensated law of demand | Slutsky substitution | Slutsky substitution | price changes and welfare | price changes and welfare | compensating variation | compensating variation | and welfare from new goods | and welfare from new goods | price indexes | price indexes | bias in the U.S. consumer price index | bias in the U.S. consumer price index | integrability | integrability | demand aggregation | demand aggregation | aggregate demand and welfare | aggregate demand and welfare | Frisch demands | Frisch demands | and demand estimation | and demand estimation | increasing differences | increasing differences | producer theory applications | producer theory applications | the LeCh?telier principle | the LeCh?telier principle | Topkis? theorem | Topkis? theorem | Milgrom-Shannon monotonicity theorem | Milgrom-Shannon monotonicity theorem | monopoly pricing | monopoly pricing | monopoly and product quality | monopoly and product quality | nonlinear pricing | nonlinear pricing | and price discrimination | and price discrimination | simple models of externalities | simple models of externalities | government intervention | government intervention | Coase theorem | Coase theorem | Myerson-Sattherthwaite proposition | Myerson-Sattherthwaite proposition | missing markets | missing markets | price vs. quantity regulations | price vs. quantity regulations | Weitzman?s analysis | Weitzman?s analysis | uncertainty | uncertainty | common property externalities | common property externalities | optimization | optimization | equilibrium number of boats | equilibrium number of boats | welfare theorems | welfare theorems | uniqueness and determinacy | uniqueness and determinacy | price-taking assumption | price-taking assumption | Edgeworth box | Edgeworth box | welfare properties | welfare properties | Pareto efficiency | Pareto efficiency | Walrasian equilibrium with transfers | Walrasian equilibrium with transfers | Arrow-Debreu economy | Arrow-Debreu economy | separating hyperplanes | separating hyperplanes | Minkowski?s theorem | Minkowski?s theorem | Existence of Walrasian equilibrium | Existence of Walrasian equilibrium | Kakutani?s fixed point theorem | Kakutani?s fixed point theorem | Debreu-Gale-Kuhn-Nikaido lemma | Debreu-Gale-Kuhn-Nikaido lemma | additional properties of general equilibrium | additional properties of general equilibrium | Microfoundations | Microfoundations | core | core | core convergence | core convergence | general equilibrium with time and uncertainty | general equilibrium with time and uncertainty | Jensen?s inequality | Jensen?s inequality | and security market economy | and security market economy | arbitrage pricing theory | arbitrage pricing theory | and risk-neutral probabilities | and risk-neutral probabilities | Housing markets | Housing markets | competitive equilibrium | competitive equilibrium | one-sided matching house allocation problem | one-sided matching house allocation problem | serial dictatorship | serial dictatorship | two-sided matching | two-sided matching | marriage markets | marriage markets | existence of stable matchings | existence of stable matchings | incentives | incentives | housing markets core mechanism | housing markets core mechanism

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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Andrew Jack, Editor at FirstFT, head of aggregation/chief curator, gives a talk for the Reuters Institute seminar series on 4th February 2015. Wales; http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

Subjects

politics | news | journalism | news aggregation | politics | news | journalism | news aggregation | 2015-02-04

License

http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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This graduate-level course introduces students to some fundamental 2D random objects, explains how they are related to each other, and explores some open problems in the field. This graduate-level course introduces students to some fundamental 2D random objects, explains how they are related to each other, and explores some open problems in the field.

Subjects

continuum random tree | continuum random tree | stable Levy tree | stable Levy tree | stable looptree | stable looptree | Gaussian free field | Gaussian free field | Schramm-Loewner evolution | Schramm-Loewner evolution | percolation | percolation | uniform spanning tree | uniform spanning tree | loop-erased random walk | loop-erased random walk | Ising model | Ising model | FK cluster model | FK cluster model | conformal loop ensemble | conformal loop ensemble | Brownian loop soup | Brownian loop soup | random planar map | random planar map | Liouville | Liouville | quantum gravity | quantum gravity | Brownian map | Brownian map | Brownian snake | Brownian snake | diffusion limited aggregation | diffusion limited aggregation | first passage percolation | first passage percolation | and dielectric breakdown model | and dielectric breakdown model | imaginary geometry | imaginary geometry | quantum zipper | quantum zipper | peanosphere | peanosphere | quantum Loewner evolution | quantum Loewner evolution

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

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Description

This course focuses on the mechanisms by which the amino acid sequence of polypeptide chains (proteins), determine their three-dimensional conformation. Topics in this course include sequence determinants of secondary structure, the folding of newly synthesized polypeptide chains within cells, folding intermediates aggregation and competing off-pathway reactions, and the unfolding and refolding of proteins in vitro. Additional topics covered are the role of helper proteins such as chaperonins and isomerases, protein recovery problems in the biotechnology industry, and diseases found associated with protein folding defects.

Subjects

amino acid sequence | polypeptide chains | sequence determinants | folding | synthesized polypeptide chains within cells | unfolding and refolding of proteins in vitro | folding intermediates aggregation | competing off-pathway reactions | chaperonins | isomerases | helper proteins | protein recovery problems | biotechnology industry | protein folding defects | 3-D conformation | globular proteins | fibrous proteins | kinetics | in vitro refolding | pathways | in vivo folding | synthesized proteins | aggregation | protein misfolding | human disease | protein folding | genome sequences | 7.88 | 5.48 | 7.24 | 10.543

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

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Description

This course covers amino acid sequence control of protein folding, misfolding, amyloid polymerization and aggregation. Readings and discussions address topics such as chaperone structure and function, folding and assembly of fibrous proteins, and pathologies associated with protein misfolding and aggregation in Alzheimer's, Parkinson's, Huntington's and other protein deposition diseases. Students are required to write and present a research paper.

Subjects

protein folding | misfolding | aggregation | protein structures | folding intermediates | off-pathway aggregation | amyloid formation | Key chaperones | chaperonins | human protein deposition diseases | ?s disease | amyloids | prions | amino acid sequence | amyloid polymerization | chaperone structure and function | folding and assembly of fibrous proteins

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Description

14.462 is the second semester of the second-year Ph.D. macroeconomics sequence. The course is intended to introduce the students, not only to particular areas of current research, but also to some very useful analytical tools. It covers a selection of topics that varies from year to year. Recent topics include: Growth and Fluctuations Heterogeneity and Incomplete Markets Optimal Fiscal Policy Time Inconsistency Reputation Coordination Games and Macroeconomic Complementarities Information

Subjects

macroeconomics research; analytical tools; analysis; endogenous growth; coordintation; incomplete markets; technolgy; distribution; employment; intellectual property rights; bounded rationality; demographics; complementarities; amplification; recursive equilibria; uncertainty; morris; shin; global games; policy; price; aggregation; social learning; dynamic adjustment; business cycle; heterogeneous agents; savings; utility; aiyagari; steady state; krusell; smith; idiosyncratic investment risk | macroeconomics research | analytical tools | analysis | endogenous growth | coordintation | incomplete markets | technolgy | distribution | employment | intellectual property rights | bounded rationality | demographics | complementarities | amplification | recursive equilibria | uncertainty | morris | shin | global games | policy | price | aggregation | social learning | dynamic adjustment | business cycle | heterogeneous agents | savings | utility | aiyagari | steady state | krusell | smith | idiosyncratic investment risk | growth | fluctuations | heterogeneity | optimal fiscal policy | time inconsistency | reputation | information | coordination games

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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JISC web2practice guide to RSS

Subjects

rss | syndication | aggregation | subscription | Technologies | J000

License

Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales Attribution-Noncommercial-Share Alike 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-sa/2.0/uk/ http://creativecommons.org/licenses/by-nc-sa/2.0/uk/

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In this webinar Walter Patterson discussed the outcomes of a recent survey of FE and HE institutions. This survey was commissioned by the Scottish Funding Council to establish the appetite for shared IT services among the respondents, identify the key business drivers and examine relevant models for the aggregation of services.

Subjects

webinar | shared services | further education | higher education | aggregation | information technology | CA : Computer Technology | SCQF Level 1

License

Attribution-NonCommercial-ShareAlike 3.0 Unported Attribution-NonCommercial-ShareAlike 3.0 Unported http://creativecommons.org/licenses/by-nc-sa/3.0/ http://creativecommons.org/licenses/by-nc-sa/3.0/ Copyright Scotland's Colleges Copyright Scotland's Colleges

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Description

This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. The instructor for this course, Dr. Kosinski-Collins, is a member of the HHMI Education Group. Maintenance of the complex three-dimensional structure adopted by a protein in the cell is vital for function. Oftentimes, as a consequence of environmental stress, genetic mutation, and/or infection, the folded structure of a protein gets altered and multiple proteins stick and fall out of solution in a process known as aggregation. In many protein aggregation diseases, incorrectly folded proteins self-associate, for

Subjects

protein folding | misfolded proteins | Mad Cow | Creutzfedt-Jakob Disease | Alzheimer's Disease | Huntington's Disease | protein aggregation | self-associate | cell death | dementia | prions | bovine spongiform encephalopathy | kuru | scrapie | protein structure | amyloid protein | amyloidosis | polyglutamine repeats | fibrils

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Description

This graduate-level course introduces students to some fundamental 2D random objects, explains how they are related to each other, and explores some open problems in the field.

Subjects

continuum random tree | stable Levy tree | stable looptree | Gaussian free field | Schramm-Loewner evolution | percolation | uniform spanning tree | loop-erased random walk | Ising model | FK cluster model | conformal loop ensemble | Brownian loop soup | random planar map | Liouville | quantum gravity | Brownian map | Brownian snake | diffusion limited aggregation | first passage percolation | and dielectric breakdown model | imaginary geometry | quantum zipper | peanosphere | quantum Loewner evolution

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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Description

This half-semester course provides an introduction to microeconomic theory designed to meet the needs of students in the economics Ph.D. program. Some parts of the course are designed to teach material that all graduate students should know. Others are used to introduce methodologies. Topics include consumer and producer theory, markets and competition, general equilibrium, and tools of comparative statics and their application to price theory. Some topics of recent interest may also be covered.

Subjects

microeconomic theory | demand theory | producer theory; partial equilibrium | competitive markets | general equilibrium | externalities | Afriat's theorem | pricing | robust comparative statics | utility theory | properties of preferences | choice as primitive | revealed preference | classical demand theory | Kuhn-Tucker necessary conditions | implications of Walras?s law | indirect utility functions | theorem of the maximum (Berge?s theorem) | expenditure minimization problem | Hicksian demands | compensated law of demand | Slutsky substitution | price changes and welfare | compensating variation | and welfare from new goods | price indexes | bias in the U.S. consumer price index | integrability | demand aggregation | aggregate demand and welfare | Frisch demands | and demand estimation | increasing differences | producer theory applications | the LeCh?telier principle | Topkis? theorem | Milgrom-Shannon monotonicity theorem | monopoly pricing | monopoly and product quality | nonlinear pricing | and price discrimination | simple models of externalities | government intervention | Coase theorem | Myerson-Sattherthwaite proposition | missing markets | price vs. quantity regulations | Weitzman?s analysis | uncertainty | common property externalities | optimization | equilibrium number of boats | welfare theorems | uniqueness and determinacy | price-taking assumption | Edgeworth box | welfare properties | Pareto efficiency | Walrasian equilibrium with transfers | Arrow-Debreu economy | separating hyperplanes | Minkowski?s theorem | Existence of Walrasian equilibrium | Kakutani?s fixed point theorem | Debreu-Gale-Kuhn-Nikaido lemma | additional properties of general equilibrium | Microfoundations | core | core convergence | general equilibrium with time and uncertainty | Jensen?s inequality | and security market economy | arbitrage pricing theory | and risk-neutral probabilities | Housing markets | competitive equilibrium | one-sided matching house allocation problem | serial dictatorship | two-sided matching | marriage markets | existence of stable matchings | incentives | housing markets core mechanism

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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