Searching for host-pathogen interactions : 4 results found | RSS Feed for this search

7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT) 7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT)

Description

Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation. Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.

Subjects

immunology | immunology | immune system | immune system | immune evasion | immune evasion | pathogen | pathogen | effector function | effector function | infections | infections | Human cytomegalovirus | Human cytomegalovirus | Human Immunodeficiency Virus | Human Immunodeficiency Virus | CD4 cells | CD4 cells | CD8 cells | CD8 cells | T cells | T cells | surace receptors | surace receptors | cell lysis | cell lysis | host-pathogen interactions | host-pathogen interactions | host surveillance | host surveillance | antibodies | antibodies | MHC class I | MHC class I | blood-borne pathogens | blood-borne pathogens | macrophages | macrophages | phagocytosis | phagocytosis | endocytosis | endocytosis | degradation | degradation | antigen | antigen | apoptosis | apoptosis | cytokines | cytokines | immune response | immune response

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.347 Living Dangerously: How the Immune System Maintains Peace with Trillions of Commensal Bacteria while Preventing Pathogenic Invasions (MIT) 7.347 Living Dangerously: How the Immune System Maintains Peace with Trillions of Commensal Bacteria while Preventing Pathogenic Invasions (MIT)

Description

In this course, we will examine how the immune system acts to destroy pathogenic invaders while tolerating colonization by necessary commensal bacteria. As a counterpoint, we will also explore sophisticated strategies that help some bacteria evade our immune system. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. In this course, we will examine how the immune system acts to destroy pathogenic invaders while tolerating colonization by necessary commensal bacteria. As a counterpoint, we will also explore sophisticated strategies that help some bacteria evade our immune system. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subjects

commensal bacteria | commensal bacteria | mucosal epithelia | mucosal epithelia | host-pathogen interactions | host-pathogen interactions | immunology | immunology | GTPase | GTPase | cell signaling | cell signaling | bacterial toxins | bacterial toxins | Campylobacter | Campylobacter | Salmonella | Salmonella | E. coli | E. coli | strain O157:H17 | gut microbiome | dysbiosis | autoimmune diseases | strain O157:H17 | gut microbiome | dysbiosis | autoimmune diseases

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

Site sourced from

http://ocw.mit.edu/rss/all/mit-allcourses-7.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.347 Living Dangerously: How the Immune System Maintains Peace with Trillions of Commensal Bacteria while Preventing Pathogenic Invasions (MIT)

Description

In this course, we will examine how the immune system acts to destroy pathogenic invaders while tolerating colonization by necessary commensal bacteria. As a counterpoint, we will also explore sophisticated strategies that help some bacteria evade our immune system. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.

Subjects

commensal bacteria | mucosal epithelia | host-pathogen interactions | immunology | GTPase | cell signaling | bacterial toxins | Campylobacter | Salmonella | E. coli | strain O157:H17 | gut microbiome | dysbiosis | autoimmune diseases

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata

7.340 Immune Evasion: How Sneaky Pathogens Avoid Host Surveillance (MIT)

Description

Every infection consists of a battle between the invading pathogen and the resisting host. To be successful, a pathogen must escape the many defenses of the host immune system until it can replicate and spread to another host. A pathogen must prevent one of three stages of immune function: detection, activation, or effector function. Examples of disease-specific immune evasion and the mechanisms used by pathogens to prevail over their hosts' immune systems are discussed. Also considered is what these host-pathogen interactions reveal about the normal function of the immune system and basic cell biological processes, such as protein maturation and degradation.

Subjects

immunology | immune system | immune evasion | pathogen | effector function | infections | Human cytomegalovirus | Human Immunodeficiency Virus | CD4 cells | CD8 cells | T cells | surace receptors | cell lysis | host-pathogen interactions | host surveillance | antibodies | MHC class I | blood-borne pathogens | macrophages | phagocytosis | endocytosis | degradation | antigen | apoptosis | cytokines | immune response

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

Site sourced from

https://ocw.mit.edu/rss/all/mit-allcourses.xml

Attribution

Click to get HTML | Click to get attribution | Click to get URL

All metadata

See all metadata