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Description
Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects of Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects ofSubjects
biological computing | biological computing | Leonard Adleman | Leonard Adleman | exquisite detection | exquisite detection | whole-cell computing | whole-cell computing | computation | computation | molecular biology | molecular biology | biotin-avidin | biotin-avidin | magnetic beads | magnetic beads | cellular processes | cellular processes | combinatorial problems | combinatorial problems | self-assembly | self-assembly | nanodevices | nanodevices | molecular machines | molecular machines | quorum sensing | quorum sensing | molecular switches | molecular switches | ciliates | ciliates | molecular gates | molecular gates | molecular circuits | molecular circuits | genetic switch | genetic switch | cellular networks | cellular networks | genetic networks | genetic networks | genetic circuits | genetic circuitsLicense
Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from
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This course covers the analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, vaccines, and cell-guiding surfaces. This course covers the analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, vaccines, and cell-guiding surfaces.Subjects
biomaterials | biomaterials | biomaterial engineering | biomaterial engineering | biotechnology | biotechnology | cell-guiding surface | cell-guiding surface | molecular biomaterials | molecular biomaterials | drug release | drug release | polymers | polymers | pulsatile release | pulsatile release | polymerization | polymerization | polyer erosion | polyer erosion | tissue engineering | tissue engineering | hydrogels | hydrogels | adhesion | adhesion | migration | migration | drug diffusion | drug diffusion | molecular switches | molecular switches | molecular motors | molecular motors | nanoparticles | nanoparticles | microparticles | microparticles | vaccines | vaccines | drug targeting | drug targeting | micro carriers | micro carriers | nano carriers | nano carriers | intracellular drug delivery | intracellular drug delivery | 20.462 | 20.462 | 3.962 | 3.962License
Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htmSite sourced from
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See all metadata7.349 Biological Computing: At the Crossroads of Engineering and Science (MIT)
Description
Imagine you are a salesman needing to visit 100 cities connected by a set of roads. Can you do it while stopping in each city only once? Even a supercomputer working at 1 trillion operations per second would take longer than the age of the universe to find a solution when considering each possibility in turn. In 1994, Leonard Adleman published a paper in which he described a solution, using the tools of molecular biology, for a smaller 7-city example of this problem. His paper generated enormous scientific and public interest, and kick-started the field of Biological Computing, the main subject of this discussion based seminar course. Students will analyze the Adleman paper, and the papers that preceded and followed it, with an eye for identifying the engineering and scientific aspects ofSubjects
biological computing | Leonard Adleman | exquisite detection | whole-cell computing | computation | molecular biology | biotin-avidin | magnetic beads | cellular processes | combinatorial problems | self-assembly | nanodevices | molecular machines | quorum sensing | molecular switches | ciliates | molecular gates | molecular circuits | genetic switch | cellular networks | genetic networks | genetic circuitsLicense
Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htmSite sourced from
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See all metadata20.462J Molecular Principles of Biomaterials (MIT)
Description
This course covers the analysis and design at a molecular scale of materials used in contact with biological systems, including biotechnology and biomedical engineering. Topics include molecular interactions between bio- and synthetic molecules and surfaces; design, synthesis, and processing approaches for materials that control cell functions; and application of state-of-the-art materials science to problems in tissue engineering, drug delivery, vaccines, and cell-guiding surfaces.Subjects
biomaterials | biomaterial engineering | biotechnology | cell-guiding surface | molecular biomaterials | drug release | polymers | pulsatile release | polymerization | polyer erosion | tissue engineering | hydrogels | adhesion | migration | drug diffusion | molecular switches | molecular motors | nanoparticles | microparticles | vaccines | drug targeting | micro carriers | nano carriers | intracellular drug delivery | 20.462 | 3.962License
Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htmSite sourced from
https://ocw.mit.edu/rss/all/mit-alllifesciencescourses.xmlAttribution
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