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15.136J Principles and Practice of Drug Development (MIT) 15.136J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate. This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

15.136 | 15.136 | 7.547 | 7.547 | 10.547 | 10.547 | ESD.691 | ESD.691 | HST.920 | HST.920 | pharmaceutical | pharmaceutical | biopharmaceutical | biopharmaceutical | drug discovery | drug discovery | preclinical development | preclinical development | clinical investigation | clinical investigation | major issues of developing drugs | major issues of developing drugs | major stages of developing drugs | major stages of developing drugs | manufacturing issues | manufacturing issues | regulatory issues | regulatory issues | economic considerations of drug development process | economic considerations of drug development process | financial considerations of drug development process | financial considerations of drug development process | clinical perspective | clinical perspective | life sciences perspective on drug development | life sciences perspective on drug development | management sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.547J Principles and Practice of Drug Development (MIT) 10.547J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate. This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

pharmaceutical | pharmaceutical | biopharmaceutical | biopharmaceutical | drug discovery | drug discovery | preclinical development | preclinical development | clinical investigation | clinical investigation | major issues of developing drugs | major issues of developing drugs | major stages of developing drugs | major stages of developing drugs | manufacturing issues | manufacturing issues | regulatory issues | regulatory issues | economic considerations of drug development process | economic considerations of drug development process | financial considerations of drug development process | financial considerations of drug development process | clinical perspective | clinical perspective | life sciences perspective on drug development | life sciences perspective on drug development | management sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.547J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

pharmaceutical | biopharmaceutical | drug discovery | preclinical development | clinical investigation | major issues of developing drugs | major stages of developing drugs | manufacturing issues | regulatory issues | economic considerations of drug development process | financial considerations of drug development process | clinical perspective | life sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.547J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

pharmaceutical | biopharmaceutical | drug discovery | preclinical development | clinical investigation | major issues of developing drugs | major stages of developing drugs | manufacturing issues | regulatory issues | economic considerations of drug development process | financial considerations of drug development process | clinical perspective | life sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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10.547J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

pharmaceutical | biopharmaceutical | drug discovery | preclinical development | clinical investigation | major issues of developing drugs | major stages of developing drugs | manufacturing issues | regulatory issues | economic considerations of drug development process | financial considerations of drug development process | clinical perspective | life sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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15.136J Principles and Practice of Drug Development (MIT)

Description

This course serves as a description and critical assessment of the major issues and stages of developing a pharmaceutical or biopharmaceutical. Topics covered include drug discovery, preclinical development, clinical investigation, manufacturing and regulatory issues considered for small and large molecules, and economic and financial considerations of the drug development process. A multidisciplinary perspective is provided by the faculty, who represent clinical, life, and management sciences. Various industry guests also participate.

Subjects

15.136 | 7.547 | 10.547 | ESD.691 | HST.920 | pharmaceutical | biopharmaceutical | drug discovery | preclinical development | clinical investigation | major issues of developing drugs | major stages of developing drugs | manufacturing issues | regulatory issues | economic considerations of drug development process | financial considerations of drug development process | clinical perspective | life sciences perspective on drug development | management sciences perspective on drug development | pharmaceutical industry guests

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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21A.215 Medical Anthropology: Culture, Society, and Ethics in Disease and Health (MIT) 21A.215 Medical Anthropology: Culture, Society, and Ethics in Disease and Health (MIT)

Description

This course looks at medicine from a cross-cultural perspective, focusing on the human, as opposed to biological, side of things. Students learn how to analyze various kinds of medical practice as cultural systems. Particular emphasis is placed on Western (bio-) medicine; students examine how biomedicine constructs disease, health, body, and mind, and how it articulates with other institutions, national and international. This course looks at medicine from a cross-cultural perspective, focusing on the human, as opposed to biological, side of things. Students learn how to analyze various kinds of medical practice as cultural systems. Particular emphasis is placed on Western (bio-) medicine; students examine how biomedicine constructs disease, health, body, and mind, and how it articulates with other institutions, national and international.

Subjects

ethics | ethics | biomedicine | biomedicine | cultural systems | cultural systems | medical practice | medical practice | health | health | disease | disease | mental illness | mental illness | leprosy | leprosy | placebo | placebo | pharmaceuticals | pharmaceuticals | racism | racism | sexism | sexism | medical institutions | medical institutions | chronic illness | chronic illness | reproductive technologies | reproductive technologies | isolation | isolation | international health | international health

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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STS.010 Neuroscience and Society (MIT) STS.010 Neuroscience and Society (MIT)

Description

This class explores the social relevance of neuroscience, considering how emerging areas of brain research reflect and reshape social attitudes and agendas. Topics include brain imaging and popular media; neuroscience of empathy, trust, and moral reasoning; new fields of neuroeconomics and neuromarketing; ethical implications of neurotechnologies such as cognitive enhancement pharmaceuticals; neuroscience in the courtroom; and neuroscientific recasting of social problems such as addiction and violence. Guest lectures by neuroscientists, class discussion, and weekly readings in neuroscience, popular media, and science studies. This class explores the social relevance of neuroscience, considering how emerging areas of brain research reflect and reshape social attitudes and agendas. Topics include brain imaging and popular media; neuroscience of empathy, trust, and moral reasoning; new fields of neuroeconomics and neuromarketing; ethical implications of neurotechnologies such as cognitive enhancement pharmaceuticals; neuroscience in the courtroom; and neuroscientific recasting of social problems such as addiction and violence. Guest lectures by neuroscientists, class discussion, and weekly readings in neuroscience, popular media, and science studies.

Subjects

cognitive science | cognitive science | evolutionary psychology | evolutionary psychology | neurobiology | neurobiology | imaging | imaging | MRI | MRI | CT scan | CT scan | fMRI | fMRI | brain | brain | mind | mind | impluse | impluse | brain imaging | brain imaging | morality | morality | moral reasoning | moral reasoning | decision making | decision making | intelligence | intelligence | empathy | empathy | trust | trust | religion | religion | love | love | emotion | emotion | gender differences | gender differences | sexuality | sexuality | stress | stress | prejudice | prejudice | mental focus | mental focus | psychopharmaceuticals | psychopharmaceuticals | antidepressant | antidepressant | neuroeconomics | neuroeconomics | neuromarketing | neuromarketing | neurotheology | neurotheology | cognitive enhancement | cognitive enhancement | witness | witness | courtroom testimony | courtroom testimony | addiction | addiction | violence | violence | learning | learning | behavior | behavior

License

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9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT) 9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT)

Description

This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. The class focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); it also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control. This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. The class focuses on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); it also examines amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation, and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems they control.

Subjects

neurotransmission | neurotransmission | nerve terminals | nerve terminals | monoamine transmitters | monoamine transmitters | acetylcholine | acetylcholine | serotonin | serotonin | dopamine | dopamine | norepinephrine | norepinephrine | amino acid and peptide transmitters | amino acid and peptide transmitters | neuromodulators | neuromodulators | adenosine | adenosine | neurotransmitter synthesis | neurotransmitter synthesis | release | release | inactivation | inactivation | receptor-mediated | receptor-mediated | second-messenger | second-messenger | neurotransmitter | neurotransmitter | antidepressant | antidepressant | brain lipid | brain lipid | blood brain barrier | blood brain barrier | parkinson's disease | parkinson's disease | seratonin | seratonin | depression | depression | glutamate | glutamate | aspartate | aspartate | NDMA | NDMA | drug | drug | drug discovery | drug discovery | pharmaceutical | pharmaceutical | signaling pathway | signaling pathway | receptor | receptor | spinal cord | spinal cord | marijuana | marijuana | adensosine | adensosine | histamine | histamine

License

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HST.921 Information Technology in the Health Care System of the Future (MIT) HST.921 Information Technology in the Health Care System of the Future (MIT)

Description

Includes audio/video content: AV faculty introductions. This innovative, trans-faculty subject teaches how information technologies (IT) are reshaping and redefining the health care marketplace through improved economies of scale, greater technical efficiencies in the delivery of care to patients, advanced tools for patient education and self-care, network integrated decision support tools for clinicians, and the emergence of e-commerce in health care. Student tutorials provide an opportunity for interactive discussion. Interdisciplinary project teams comprised of Harvard and MIT graduate students in medicine, business, law, education, engineering, computer science, public health, and government collaborate to design innovative IT applications. Projects are presented during the final class Includes audio/video content: AV faculty introductions. This innovative, trans-faculty subject teaches how information technologies (IT) are reshaping and redefining the health care marketplace through improved economies of scale, greater technical efficiencies in the delivery of care to patients, advanced tools for patient education and self-care, network integrated decision support tools for clinicians, and the emergence of e-commerce in health care. Student tutorials provide an opportunity for interactive discussion. Interdisciplinary project teams comprised of Harvard and MIT graduate students in medicine, business, law, education, engineering, computer science, public health, and government collaborate to design innovative IT applications. Projects are presented during the final class

Subjects

health care | health care | health care policy | health care policy | patient behavior | patient behavior | information management | information management | medical informatics | medical informatics | medical records | medical records | health record | health record | online medicine | online medicine | PHR | PHR | EHR | EHR | patient privacy | patient privacy | entrepreneurship | entrepreneurship | start-up | start-up | innovation | innovation | cybermedicine | cybermedicine | telemedicine | telemedicine | non-profit | non-profit | pharmaceutical | pharmaceutical | insurance | insurance | hospital | hospital | doctor | doctor | patient | patient | medicine | medicine | social networking | social networking | economies of scale | economies of scale | patient education | patient education | self-care | self-care | network integration | network integration | decision support tools | decision support tools | disease managment | disease managment | health economics | health economics | clinical effectiveness | clinical effectiveness | medical software | medical software | mobile applications | mobile applications | intellectual property | intellectual property

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.341 Harnessing the Biosphere: Natural Products and Biotechnology (MIT) 7.341 Harnessing the Biosphere: Natural Products and Biotechnology (MIT)

Description

What do the organisms of the biosphere, specifically microorganisms, have to offer to biotechnological endeavors? In this course we will focus on the production of biomolecules using microbial systems. We will discuss potential growth substrates (such as agricultural waste and carbon dioxide) that can be used and learn about both established and cutting-edge manipulation techniques in the field of synthetic biology. We will also cover the production of biofuels, bioplastics, amino acids (e.g. lysine), food additives (e.g. monosodium glutamate, MSG), specialty chemicals (e.g. succinate), and biopharmaceuticals (e.g. plasmids for gene therapy). This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an What do the organisms of the biosphere, specifically microorganisms, have to offer to biotechnological endeavors? In this course we will focus on the production of biomolecules using microbial systems. We will discuss potential growth substrates (such as agricultural waste and carbon dioxide) that can be used and learn about both established and cutting-edge manipulation techniques in the field of synthetic biology. We will also cover the production of biofuels, bioplastics, amino acids (e.g. lysine), food additives (e.g. monosodium glutamate, MSG), specialty chemicals (e.g. succinate), and biopharmaceuticals (e.g. plasmids for gene therapy). This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an

Subjects

microorganisms | microorganisms | biomolecules | biomolecules | microbial systems | microbial systems | synthetic biology | synthetic biology | biofuels | biofuels | bioplastics | bioplastics | amino acids | amino acids | lysine | lysine | food additives | food additives | monosodium glutamate (MSG) | monosodium glutamate (MSG) | specialty chemicals | specialty chemicals | succinate | succinate | biopharmaceuticals | biopharmaceuticals | enzymes | enzymes | antibiotics and biocompatible materials | antibiotics and biocompatible materials | microbial biotechnology | microbial biotechnology | genetic engineering | genetic engineering

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT) 9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT)

Description

This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered. This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered.

Subjects

Neurotransmitter | Neurotransmitter | antidepressant | antidepressant | brain lipid | brain lipid | blood brain barrier | blood brain barrier | dopamine | dopamine | parkinson's disease | parkinson's disease | serotonin | serotonin | depression | depression | glutamate | glutamate | aspartate | aspartate | NDMA | NDMA | drug | drug | drug discovery | drug discovery | pharmaceutical | pharmaceutical | signaling pathway | signaling pathway | receptor | receptor | spinal cord | spinal cord | marijuana | marijuana | adensosine | adensosine | histamine. | histamine.

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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15.225 Economy and Business in Modern China and India (MIT) 15.225 Economy and Business in Modern China and India (MIT)

Description

As markets or production bases, China and India are becoming important and integral players in the global economy. Foreign direct investment (FDI), portfolio investments and outsourcing businesses have increased dramatically in these two economies. Despite the rising importance of these two economies on the world stage, our knowledge and analysis of these two countries in an integrated manner has remained poor. The two are often lumped together by business analysts as "emerging markets," despite the substantial differences in their political systems, reform policies and business organizations. Academics, in contrast, have tended to treat the two countries separately, preferring to specialize in issues and questions specific to one or the other country. The purpose of this course is to an As markets or production bases, China and India are becoming important and integral players in the global economy. Foreign direct investment (FDI), portfolio investments and outsourcing businesses have increased dramatically in these two economies. Despite the rising importance of these two economies on the world stage, our knowledge and analysis of these two countries in an integrated manner has remained poor. The two are often lumped together by business analysts as "emerging markets," despite the substantial differences in their political systems, reform policies and business organizations. Academics, in contrast, have tended to treat the two countries separately, preferring to specialize in issues and questions specific to one or the other country. The purpose of this course is to an

Subjects

China | China | India | India | global economy | global economy | growth | growth | foreign direct investment | foreign direct investment | portfolio investments | portfolio investments | emerging markets | emerging markets | reform policies | reform policies | business environment | business environment | financing environment | financing environment | corruption | corruption | business government relationship | business government relationship | venture capital | venture capital | private equity | private equity | intellectual property | intellectual property | India pharmaceutical industry | India pharmaceutical industry | development models. | development models.

License

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20.453J Biomedical Information Technology (MIT) 20.453J Biomedical Information Technology (MIT)

Description

This course teaches the design of contemporary information systems for biological and medical data. Examples are chosen from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (e.g. C, C++, Java, Lisp, Perl, Python). A major term project is required of all students. This subject is open to motivated seniors having a strong interest in biomedical engineering and information system desig This course teaches the design of contemporary information systems for biological and medical data. Examples are chosen from biology and medicine to illustrate complete life cycle information systems, beginning with data acquisition, following to data storage and finally to retrieval and analysis. Design of appropriate databases, client-server strategies, data interchange protocols, and computational modeling architectures. Students are expected to have some familiarity with scientific application software and a basic understanding of at least one contemporary programming language (e.g. C, C++, Java, Lisp, Perl, Python). A major term project is required of all students. This subject is open to motivated seniors having a strong interest in biomedical engineering and information system desig

Subjects

20.453 | 20.453 | 2.771 | 2.771 | HST.958 | HST.958 | imaging | imaging | medical imaging | medical imaging | metadata | metadata | molecular biology | molecular biology | medical records | medical records | DICOM | DICOM | RDF | RDF | OWL | OWL | SPARQL | SPARQL | SBML | SBML | CellML | CellML | semantic web | semantic web | BioHaystack | BioHaystack | database | database | schema | schema | ExperiBase | ExperiBase | genomics | genomics | proteomics | proteomics | bioinformatics | bioinformatics | computational biology | computational biology | clinical decision support | clinical decision support | clinical trial | clinical trial | microarray | microarray | gel electrophoresis | gel electrophoresis | diagnosis | diagnosis | pathway modeling | pathway modeling | XML | XML | SQL | SQL | relational database | relational database | biological data | biological data | ontologies | ontologies | drug development | drug development | drug discovery | drug discovery | drug target | drug target | pharmaceutical | pharmaceutical | gene sequencing | gene sequencing

License

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ESD.85J Integrating Doctoral Seminar on Emerging Technologies (MIT) ESD.85J Integrating Doctoral Seminar on Emerging Technologies (MIT)

Description

This team-taught subject is for doctoral students working on emerging technologies at the interface of technology, policy and societal issues. It integrates concepts of research strategy and design from a variety of disciplines. The class addresses problem identification and formulation of research topics, the role of qualitative and quantitative research methods, and the use of various data collection techniques. Coursework focuses on students' thesis proposals, faculty-student study panels, critical evaluation of research design, and ethical issues in conducting research and gathering data. This team-taught subject is for doctoral students working on emerging technologies at the interface of technology, policy and societal issues. It integrates concepts of research strategy and design from a variety of disciplines. The class addresses problem identification and formulation of research topics, the role of qualitative and quantitative research methods, and the use of various data collection techniques. Coursework focuses on students' thesis proposals, faculty-student study panels, critical evaluation of research design, and ethical issues in conducting research and gathering data.

Subjects

ESD.85 | ESD.85 | 17.312 | 17.312 | STS.461 | STS.461 | uncertainty | uncertainty | risk | risk | politics | politics | forecasting | forecasting | future | future | prediction | prediction | disaster | disaster | space shuttle | space shuttle | nuclear power | nuclear power | nuclear energy | nuclear energy | energy policy | energy policy | government | government | technology assessment | technology assessment | OTA | OTA | GPS | GPS | internet | internet | packet switching | packet switching | data network | data network | military | military | DEC | DEC | Digital Equipment | Digital Equipment | drug | drug | pharmaceutical | pharmaceutical | air transport | air transport | aircraft | aircraft | public policy | public policy | industrial policy | industrial policy | UAV | UAV | decision | decision

License

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HST.939 Designing and Sustaining Technology Innovation for Global Health Practice (MIT) HST.939 Designing and Sustaining Technology Innovation for Global Health Practice (MIT)

Description

Innovation in global health practice requires leaders who are trained to think and act like entrepreneurs. Whether at a hospital bedside or in a remote village, global healthcare leaders must understand both the business of running a social venture as well as how to plan for and provide access to life saving medicines and essential health services. Each week, the course features a lecture and skills-based tutorial session led by industry, non-profit foundation, technology, and academic leaders to think outside the box in tackling and solving problems in innovation for global health practice through the rationale design of technology and service solutions. The lectures provide the foundation for faculty-mentored pilot project from MOH, students, or non-profit sponsors that may involve creat Innovation in global health practice requires leaders who are trained to think and act like entrepreneurs. Whether at a hospital bedside or in a remote village, global healthcare leaders must understand both the business of running a social venture as well as how to plan for and provide access to life saving medicines and essential health services. Each week, the course features a lecture and skills-based tutorial session led by industry, non-profit foundation, technology, and academic leaders to think outside the box in tackling and solving problems in innovation for global health practice through the rationale design of technology and service solutions. The lectures provide the foundation for faculty-mentored pilot project from MOH, students, or non-profit sponsors that may involve creat

Subjects

global health | global health | developing countries | developing countries | third world | third world | Africa | Africa | underserved population | underserved population | rural medicine | rural medicine | health technology | health technology | health ventures | health ventures | medical technology | medical technology | medical innovation | medical innovation | entrepreneurship | entrepreneurship | non-profit | non-profit | pharmaceutical design | pharmaceutical design | rapid diagnostic test | rapid diagnostic test | systems design | systems design | student projects | student projects | field work | field work | mentor program | mentor program | interdisciplinary | interdisciplinary | health economics | health economics | disease management | disease management | drug distribution | drug distribution

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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STS.010 Neuroscience and Society (MIT) STS.010 Neuroscience and Society (MIT)

Description

This course explores the social relevance of neuroscience, considering how emerging areas of brain research at once reflect and reshape social attitudes and agendas. Topics include brain imaging and popular media; neuroscience of empathy, trust, and moral reasoning; new fields of neuroeconomics and neuromarketing; ethical implications of neurotechnologies such as cognitive enhancement pharmaceuticals; neuroscience in the courtroom; and neuroscientific recasting of social problems such as addiction and violence. Guest lectures by neuroscientists, class discussion, and weekly readings in neuroscience, popular media, and science studies. This course explores the social relevance of neuroscience, considering how emerging areas of brain research at once reflect and reshape social attitudes and agendas. Topics include brain imaging and popular media; neuroscience of empathy, trust, and moral reasoning; new fields of neuroeconomics and neuromarketing; ethical implications of neurotechnologies such as cognitive enhancement pharmaceuticals; neuroscience in the courtroom; and neuroscientific recasting of social problems such as addiction and violence. Guest lectures by neuroscientists, class discussion, and weekly readings in neuroscience, popular media, and science studies.

Subjects

cognitive science | cognitive science | evolutionary psychology | evolutionary psychology | neurobiology | neurobiology | brain imaging | brain imaging | MRI | MRI | CT scan | CT scan | fMRI | fMRI | brain | brain | mind | mind | morality | morality | moral reasoning | moral reasoning | decision making | decision making | intelligence | intelligence | empathy | empathy | trust | trust | religion | religion | love | love | emotion | emotion | gender differences | gender differences | sexuality | sexuality | stress | stress | prejudice | prejudice | attention | attention | psychopharmaceuticals | psychopharmaceuticals | antidepressant | antidepressant | neuroeconomics | neuroeconomics | neuromarketing | neuromarketing | neurotheology | neurotheology | cognitive enhancement | cognitive enhancement | witness | witness | courtroom testimony | courtroom testimony | addiction | addiction | violence | violence | learning | learning | behavior | behavior

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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20.201 Mechanisms of Drug Actions (MIT) 20.201 Mechanisms of Drug Actions (MIT)

Description

This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets. This course addresses the scientific basis for the development of new drugs. The first half of the semester begins with an overview of the drug discovery process, followed by fundamental principles of pharmacokinetics, pharmacodynamics, metabolism, and the mechanisms by which drugs cause therapeutic and toxic responses. The second half of the semester applies those principles to case studies and literature discussions of current problems with specific drugs, drug classes, and therapeutic targets.

Subjects

drugs | drugs | medicine | medicine | pharmaceutical | pharmaceutical | pharmacology | pharmacology | toxicology | toxicology | drug actions | drug actions | therapeutics | therapeutics | histology | histology | pathophysiology | pathophysiology | drug therapy | drug therapy | drug transporters | drug transporters | drug metabolism | drug metabolism | drug toxicity | drug toxicity | drug development | drug development | uptake | uptake | transport | transport | case study | case study | biochemistry | biochemistry | Pharmacokinetics | Pharmacokinetics | Pharmacogenetics | Pharmacogenetics | Omeprazole | Omeprazole | antibiotics | antibiotics | Oncology | Oncology | Statins | Statins | Sarilumab | Sarilumab | cystic fibrosis | cystic fibrosis

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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21A.302J Dilemmas in Bio-Medical Ethics: Playing God or Doing Good? (MIT) 21A.302J Dilemmas in Bio-Medical Ethics: Playing God or Doing Good? (MIT)

Description

This course is an introduction to the cross-cultural study of biomedical ethics, examining moral foundations of the science and practice of Western biomedicine through case studies of abortion, contraception, cloning, organ transplantation and other issues. It evaluates challenges that new medical technologies pose to the practice and availability of medical services around the globe, and to cross-cultural ideas of kinship and personhood. Also discussed are critiques of the biomedical tradition from anthropological, feminist, legal, religious, and cross-cultural theorists. This course is an introduction to the cross-cultural study of biomedical ethics, examining moral foundations of the science and practice of Western biomedicine through case studies of abortion, contraception, cloning, organ transplantation and other issues. It evaluates challenges that new medical technologies pose to the practice and availability of medical services around the globe, and to cross-cultural ideas of kinship and personhood. Also discussed are critiques of the biomedical tradition from anthropological, feminist, legal, religious, and cross-cultural theorists.

Subjects

21A.302 | 21A.302 | WGS.271 | WGS.271 | bio-medical ethics | bio-medical ethics | medical technologies | medical technologies | biotechnologies | biotechnologies | halth | halth | sexuality | sexuality | morality | morality | race | race | ethnicity | ethnicity | kinship | kinship | gender | gender | abortion | abortion | contraception | contraception | reproductive technologies | reproductive technologies | pharmaceuticals | pharmaceuticals | end of life care | end of life care | healing practices | healing practices | anthropology | anthropology | medical experimentation | medical experimentation | sterilization | sterilization | Lynchburg | Lynchburg | biological citizenship | biological citizenship | clinical trials | clinical trials

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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WGS.645 Gender, Health and Marginalization Through a Critical Feminist Lens (MIT) WGS.645 Gender, Health and Marginalization Through a Critical Feminist Lens (MIT)

Description

In the course we will use a feminist interdisciplinary lens and invite students to look critically at how practices like privatization, shrinking public "safety nets", de-regulation, and the commodification of health services intersect inevitably with gender, race and class, for both men and women. We will draw on a blend of empirical studies, policy materials, films and guest speakers to examine specific health issues like menstrual health, corporate obstetrics, abortion, obesity, intersex, harassment and other forms of gendered violence, mental health and stress, parent-child attachment, as well as ethics and pharmaceuticals. The Graduate Consortium in Women's Studies (GCWS) This course is part of the Graduate Consortium in Women's In the course we will use a feminist interdisciplinary lens and invite students to look critically at how practices like privatization, shrinking public "safety nets", de-regulation, and the commodification of health services intersect inevitably with gender, race and class, for both men and women. We will draw on a blend of empirical studies, policy materials, films and guest speakers to examine specific health issues like menstrual health, corporate obstetrics, abortion, obesity, intersex, harassment and other forms of gendered violence, mental health and stress, parent-child attachment, as well as ethics and pharmaceuticals. The Graduate Consortium in Women's Studies (GCWS) This course is part of the Graduate Consortium in Women's

Subjects

gender | gender | health | health | marginalization | marginalization | feminist | feminist | neo-liberal | neo-liberal | menstrual health | menstrual health | corporate obstetrics | corporate obstetrics | abortion | abortion | obesity | obesity | intersex | intersex | harassment | harassment | mental health | mental health | stress | stress | parenting | parenting | ethics | ethics | pharmaceuticals | pharmaceuticals | women | women | men | men

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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9.15 Biochemistry and Pharmacology of Synaptic Transmission (MIT)

Description

This course considers the process of neurotransmission, especially chemicals used in the brain and elsewhere to carry signals from nerve terminals to the structures they innervate. We focus on monoamine transmitters (acetylcholine; serotonin; dopamine and norepinephrine); we also examine amino acid and peptide transmitters and neuromodulators like adenosine. Macromolecules that mediate neurotransmitter synthesis, release, inactivation and receptor-mediated actions are discussed, as well as factors that regulate their activity and the second-messenger systems and ion fluxes that they control. The involvement of particular neurotransmitters in human diseases is considered.

Subjects

Neurotransmitter | antidepressant | brain lipid | blood brain barrier | dopamine | parkinson's disease | serotonin | depression | glutamate | aspartate | NDMA | drug | drug discovery | pharmaceutical | signaling pathway | receptor | spinal cord | marijuana | adensosine | histamine.

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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New Drugs for Old Case Study

Description

This is a problem solving case study which maps the devlopment of a new pharmaceutical product from the observation of biological activity to the market place. Used with chemistry and pharmaceutical science students at level 4 and 5.

Subjects

sfsoer | ukoer | chemistry | pharmaceutical | analytical | case study | problem-based learning | Physical sciences | F000

License

Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales http://creativecommons.org/licenses/by-nc-nd/2.0/uk/ http://creativecommons.org/licenses/by-nc-nd/2.0/uk/

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Laboratory Operations (Working in the Science Industry Unit 2)

Description

This unit is a SCORM package and needs to run on an LMS platform. This unit is covered within the Apprenticeship Framework for Laboratory Operations. It is also covered as a standalone qualification within the BTEC Extended Diploma. The unit supports the level 3 BTEC Subsidiary Diploma in Applied Science and the level 3 BTEC Extended Diploma. The unit covers the importance in communication, laboratory design and information management. The apprentice would also learn how to work safely in a scientific workplace. It is designed as a blended learning unit for study with the support of a tutor or workplace mentor

Subjects

laboratory | science industries | ILRforSkills | roles and responsibilities | waste disposal | scientific data | procedures | physical laboratories | laboratory operations | pharmaceutical laboratories | safe handling | stock control | laboratory equipment | accessing data | food laboratories | chemical laboratories | medical laboratories | forensic laboratories | specialist laboratories | compliance | quality standards | hazard labelling | training records | HEALTH CARE / MEDICINE / HEALTH and SAFETY | P

License

Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ http://creativecommons.org/licenses/by-nc-sa/4.0/

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Articulate file Laboratory Operations (Working in the Science Industry Unit 2)

Description

This is the unit source file and has been created in Articulate Storyline2. If you have experience with Storyline2 and have a licence you will be able to customise the unit for your own purposes. Please note under the Creative Commons licence if you republish the unit it should be made freely available to others. This unit is covered within the Apprenticeship Framework for Laboratory Operations. It is also covered as a standalone qualification within the BTEC Extended Diploma. The unit supports the level 3 BTEC Subsidiary Diploma in Applied Science and the level 3 BTEC Extended Diploma. The unit covers the importance in communication, laboratory design and information management. The apprentice would also learn how to work safely in a scientific workplace. It is designed as a blended learn

Subjects

ILRforSkills | science industries | laboratory | laboratory operations | procedures | laboratory equipment | safe handling | waste disposal | roles and responsibilities | specialist laboratories | chemical laboratories | medical laboratories | food laboratories | physical laboratories | forensic laboratories | pharmaceutical laboratories | accessing data | stock control | scientific data | training records | hazard labelling | quality standards | compliance | HEALTH CARE / MEDICINE / HEALTH and SAFETY | P

License

Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ http://creativecommons.org/licenses/by-nc-sa/4.0/

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Articulate file Laboratory Operations (Working in the Science Industry Unit 2)

Description

This is the unit source file and has been created in Articulate Storyline2. If you have experience with Storyline2 and have a licence you will be able to customise the unit for your own purposes. Please note under the Creative Commons licence if you republish the unit it should be made freely available to others. This unit is covered within the Apprenticeship Framework for Laboratory Operations. It is also covered as a standalone qualification within the BTEC Extended Diploma. The unit supports the level 3 BTEC Subsidiary Diploma in Applied Science and the level 3 BTEC Extended Diploma. The unit covers the importance in communication, laboratory design and information management. The apprentice would also learn how to work safely in a scientific workplace. It is designed as a blended learn

Subjects

ILRforSkills | science industries | laboratory | laboratory operations | procedures | laboratory equipment | safe handling | waste disposal | roles and responsibilities | specialist laboratories | chemical laboratories | medical laboratories | food laboratories | physical laboratories | forensic laboratories | pharmaceutical laboratories | accessing data | stock control | scientific data | training records | hazard labelling | quality standards | compliance | HEALTH CARE / MEDICINE / HEALTH and SAFETY | P

License

Attribution-NonCommercial-ShareAlike 4.0 International Attribution-NonCommercial-ShareAlike 4.0 International http://creativecommons.org/licenses/by-nc-sa/4.0/ http://creativecommons.org/licenses/by-nc-sa/4.0/

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