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7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT) 7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT)

Description

The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an

Subjects

immune system | immune system | immunoengineering | immunoengineering | vaccines | vaccines | immunotherapies | immunotherapies | systems immunology | systems immunology | multivariate profiling | multivariate profiling | regulatory network analyses | regulatory network analyses | vaccine design | vaccine design | immunomodulation | immunomodulation | autoimmunity | autoimmunity | vaccine carriers | vaccine carriers | tolerogenic particle vaccines | tolerogenic particle vaccines | pathogen-mimicking | pathogen-mimicking | lipid nanoparticle vaccines | lipid nanoparticle vaccines

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT)

Description

The immune system is one of the most complex and powerful of human body systems. It is highly dynamic and flexible, yet strictly regulates homeostasis and protects our bodies from both foreign and self-derived challenges. As basic understanding of immune function is growing, researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health. In this course, we will explore important advances rooted in engineering principles to harness the power of the immune system, focusing on how engineering has fueled or inspired research concerning (1) vaccines, (2) immunotherapies, and (3) systems immunology. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an

Subjects

immune system | immunoengineering | vaccines | immunotherapies | systems immunology | multivariate profiling | regulatory network analyses | vaccine design | immunomodulation | autoimmunity | vaccine carriers | tolerogenic particle vaccines | pathogen-mimicking | lipid nanoparticle vaccines

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see https://ocw.mit.edu/terms/index.htm

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B0017P0001

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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B0017P0002

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | cats | kittens | feline | felines | healthykitten | healthycat | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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B0017P0003

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | cats | kittens | feline | felines | healthykitten | healthycat | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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B0017P0004

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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B0024P0001

Description

A kitten having a vaccination

Subjects

svmsvet | cat | kitten | vaccination | vaccine | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens | b0024

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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C0000P0066

Description

Subjects

svmsvet | drugs | vaccine | rabbits | cylap | rabbitvaccine | injection | viralhaemorrhagicdiseasevaccine | vhdvaccine

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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C0000P0132

Description

i-CHPChlam

Subjects

svmsvet | drugs | drug | vaccine | catvaccine | ichpchlam | fevaxyn | cat | vaccination | chlamydophilavaccine | cfelisvaccine

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0000P0005

Description

A Virbagen RCP cat vaccine.

Subjects

svmsvet | drug | vaccine | catvaccination | catvaccine | felinevaccine | virbagen | rcpvaccine | rcp | injectable | syringe

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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B0017P0001

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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B0017P0002

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | cats | kittens | feline | felines | healthykitten | healthycat | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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B0017P0003

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | cats | kittens | feline | felines | healthykitten | healthycat | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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B0017P0004

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccine | check | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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B0024P0001

Description

A kitten having a vaccination

Subjects

svmsvet | cat | kitten | vaccination | vaccine | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens | b0024

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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C0000P0066

Description

Subjects

svmsvet | drugs | vaccine | rabbits | cylap | rabbitvaccine | injection | viralhaemorrhagicdiseasevaccine | vhdvaccine

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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C0000P0132

Description

i-CHPChlam

Subjects

svmsvet | drugs | drug | vaccine | catvaccine | ichpchlam | fevaxyn | cat | vaccination | chlamydophilavaccine | cfelisvaccine

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

Attribution

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A0000P0005

Description

A Virbagen RCP cat vaccine.

Subjects

svmsvet | drug | vaccine | catvaccination | catvaccine | felinevaccine | virbagen | rcpvaccine | rcp | injectable | syringe

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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6.891 Computational Evolutionary Biology (MIT) 6.891 Computational Evolutionary Biology (MIT)

Description

Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data. Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS? Has there been natural selection for a 'language gene'? Why are there no animals with wheels? When does 'maximizing fitness' lead to evolutionary extinction? How are sex and parasites related? Why don't snakes eat grass? Why don't we have eyes in the back of our heads? How does modern genomics illustrate and challenge the field? This course analyzes evolution from a computational, modeling, and engineering perspective. The course has extensive hands-on laboratory exercises in model-building and analyzing evolutionary data.

Subjects

evolution from a computational | evolution from a computational | modeling | modeling | and engineering perspective | and engineering perspective | analyzing evolutionary data | analyzing evolutionary data | vaccine | vaccine | polio | polio | influenza | influenza | AIDS | AIDS | evolutionary extinction | evolutionary extinction | sex | sex | parasites | parasites | modern genomics | modern genomics | polio vaccine | polio vaccine | hands-on | hands-on | evolution from a computational | modeling | and engineering perspective | evolution from a computational | modeling | and engineering perspective

License

Content within individual OCW courses is (c) by the individual authors unless otherwise noted. MIT OpenCourseWare materials are licensed by the Massachusetts Institute of Technology under a Creative Commons License (Attribution-NonCommercial-ShareAlike). For further information see http://ocw.mit.edu/terms/index.htm

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B0045P0001

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccination | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

Site sourced from

Nottingham Vet School | FlickR

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B0045P0002

Description

A kitten presenting for routine vaccination

Subjects

svmsvet | cat | kitten | vaccination | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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Nottingham Vet School | FlickR

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B0045P0003

Description

A vet discusses kitten care issues and preventative medicine with a client

Subjects

svmsvet | cat | kitten | vaccination | client | vet | communication | kittenvaccine | kittenvaccination | catvaccine | catvacination | felinevaccine | felinevacination | cats | feline | felines | kittens

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0032P0002

Description

A 3 month old female kitten presented for first vaccination

Subjects

svmsvet | cat | kitten | cats | feline | felines | kittens | vaccination | firstvaccine | catvaccine | catvaccination | kittenvaccine | kittenvaccination | a0032

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0032P0001

Description

A 3 month old female kitten presented for first vaccination

Subjects

svmsvet | cat | kitten | cats | feline | felines | kittens | vaccination | firstvaccine | catvaccine | catvaccination | kittenvaccine | kittenvaccination | a0032

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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A0031P0001

Description

A 3 month old female kitten presenting for first vaccination.

Subjects

svmsvet | cat | kitten | cats | feline | felines | kittens | vaccination | firstvaccine | catvaccine | catvaccination | kittenvaccine | kittenvaccination | a0032

License

http://creativecommons.org/licenses/by-nc-sa/2.0/

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