RSS Feed for vaccine https://solvonauts.org/%3Faction%3Drss_search%26term%3Dvaccine RSS Feed for vaccine 7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT) 7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT) The immune system is one of the most complex and powerful of human body systems It is highly dynamic and flexible yet strictly regulates homeostasis and protects our bodies from both foreign and self derived challenges As basic understanding of immune function is growing researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health In this course we will explore important advances rooted in engineering principles to harness the power of the immune system focusing on how engineering has fueled or inspired research concerning 1 vaccines 2 immunotherapies and 3 systems immunology This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT These seminars are tailored for students with an The immune system is one of the most complex and powerful of human body systems It is highly dynamic and flexible yet strictly regulates homeostasis and protects our bodies from both foreign and self derived challenges As basic understanding of immune function is growing researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health In this course we will explore important advances rooted in engineering principles to harness the power of the immune system focusing on how engineering has fueled or inspired research concerning 1 vaccines 2 immunotherapies and 3 systems immunology This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT These seminars are tailored for students with an http://ocw.mit.edu/courses/biology/7-341-designer-immunity-lessons-in-engineering-the-immune-system-spring-2014 http://ocw.mit.edu/courses/biology/7-341-designer-immunity-lessons-in-engineering-the-immune-system-spring-2014 Tuberculosis Dr Helen McShane has been working on a new TB vaccine for 10 years She explains why developing countries are especially in need of a new vaccine since HIV and TB epidemics overlap and show a devastating synergy There are about 9 million new cases and 1 7 million deaths every year from tuberculosis Dr Helen McShane developed MVA85A a vaccine with the aim to boost the cellular immune response induced by BCG BCG now over 100 years old remains the only licensed vaccine against Tuberculosis It confers good protection against severe disease and meningitis but doesn t protect against lung disease MVA85A was the first vaccine of the new generation to enter into efficacy testing It is currently being tested in The Gambia Senegal and South Africa Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/07_helen_mcshane.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/07_helen_mcshane.mp3 Tuberculosis Dr Helen McShane has been working on a new TB vaccine for 10 years She explains why developing countries are especially in need of a new vaccine since HIV and TB epidemics overlap and show a devastating synergy There are about 9 million new cases and 1 7 million deaths every year from tuberculosis Dr Helen McShane developed MVA85A a vaccine with the aim to boost the cellular immune response induced by BCG BCG now over 100 years old remains the only licensed vaccine against Tuberculosis It confers good protection against severe disease and meningitis but doesn t protect against lung disease MVA85A was the first vaccine of the new generation to enter into efficacy testing It is currently being tested in The Gambia Senegal and South Africa Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/07_helen_mcshane.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/07_helen_mcshane.mp4 Can we block malaria transmission by Sumi Biswas Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle Malaria transmission blocking vaccines aim to induce immunity against the parasites that infect mosquitoes Such vaccines will prevent malaria transmission on a wider scale focusing on the community rather than the individual Dr Sumi Biswas is working on the development of transmission blocking vaccines to prevent the spread of malaria http://media.podcasts.ox.ac.uk/clmed/translational/2013-4-25-clmed-biswas.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/2013-4-25-clmed-biswas.mp3 Viral vectored vaccine development Professor Sarah Gilbert talks about her work on viral vectored vaccines Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years chiefly using antigens from malaria and influenza Based at the Jenner Institute several of the vaccines developed in Professor Gilberts laboratory have progressed into Clinical Trials Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/sarah_gilbert.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/sarah_gilbert.mp3 Viral vectored vaccine development Professor Sarah Gilbert talks about her work on viral vectored vaccines Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years chiefly using antigens from malaria and influenza Based at the Jenner Institute several of the vaccines developed in Professor Gilberts laboratory have progressed into Clinical Trials Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/sarah_gilbert.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/sarah_gilbert.mp4 6.891 Computational Evolutionary Biology (MIT) 6.891 Computational Evolutionary Biology (MIT) Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS Has there been natural selection for a language gene Why are there no animals with wheels When does maximizing fitness lead to evolutionary extinction How are sex and parasites related Why don t snakes eat grass Why don t we have eyes in the back of our heads How does modern genomics illustrate and challenge the field This course analyzes evolution from a computational modeling and engineering perspective The course has extensive hands on laboratory exercises in model building and analyzing evolutionary data Why has it been easier to develop a vaccine to eliminate polio than to control influenza or AIDS Has there been natural selection for a language gene Why are there no animals with wheels When does maximizing fitness lead to evolutionary extinction How are sex and parasites related Why don t snakes eat grass Why don t we have eyes in the back of our heads How does modern genomics illustrate and challenge the field This course analyzes evolution from a computational modeling and engineering perspective The course has extensive hands on laboratory exercises in model building and analyzing evolutionary data http://dspace.mit.edu/handle/1721.1/89823 http://dspace.mit.edu/handle/1721.1/89823 7.341 Designer Immunity: Lessons in Engineering the Immune System (MIT) The immune system is one of the most complex and powerful of human body systems It is highly dynamic and flexible yet strictly regulates homeostasis and protects our bodies from both foreign and self derived challenges As basic understanding of immune function is growing researchers are rapidly designing clever and diverse strategies to manipulate immunology to improve human health In this course we will explore important advances rooted in engineering principles to harness the power of the immune system focusing on how engineering has fueled or inspired research concerning 1 vaccines 2 immunotherapies and 3 systems immunology This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT These seminars are tailored for students with an https://ocw.mit.edu/courses/biology/7-341-designer-immunity-lessons-in-engineering-the-immune-system-spring-2014 https://ocw.mit.edu/courses/biology/7-341-designer-immunity-lessons-in-engineering-the-immune-system-spring-2014 Progress in Malaria Vaccine Research Dr Simon Draper tells us about his progress in malaria vaccine research Dr Simon Draper s research interests include studies of vaccine induced malaria immunity His group focuses on translational medicine They will take their most promising vaccine candidates and manufacture them as clinical grade material The next step is proof of concept clinical trials in healthy volunteers Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/simon_draper.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/simon_draper.mp3 Malaria vaccine for P. vivax Dr Arturo Reyes Sandoval tells us about his research on a vaccine against Plasmodium vivax Dr Reyes Sandoval aims to develop a novel malaria vaccine against Plasmodium vivax one of the four malaria parasites that affect humans P vivax is found in Africa Asia Latin America and the Western Pacific 40 percent of the world s population is exposed to the disease that is responsible for around 130 to 350 million clinical cases every year Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/arturo_reyes-sandoval.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/arturo_reyes-sandoval.mp3 HIV Vaccine Development Professor Tomas Hanke tells us about his research on HIV vaccine development The long term aim for Professor Tom Hanke is to develop a safe effective and accessible HIV 1 vaccine His group tests novel ideas and vaccine strategies and focusses on a safe but rapid translation of the most promising laboratory results to phase I II clinical trials in human volunteers Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/38_tomas_hanke.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/38_tomas_hanke.mp3 Hepatitis C vaccine Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine Dr Ellie Barnes aims to develop a prophylactic and a therapeutic hepatitis C virus vaccine to combat a global epidemic currently infecting 170 million people worldwide Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer liver cirrhosis and liver failure Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/32_ellie_barnes.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/32_ellie_barnes.mp3 Aiming for a HIV vaccine Professor Sir Andrew McMichael tells us about recent developments in the search for a vaccine against HIV Prof Sir Andrew McMichael is working on human immunology and vaccines first looking at flu virus and now HIV His current lines of research include analysing early molecular events in HIV infection T cell immune response to HIV and the use of vaccination to control HIV infection Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/19_andrew_mcmichael.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/19_andrew_mcmichael.mp3 Malaria Vaccines Professor Adrian Hill has been studying the immune system and malaria susceptibility in African children for years We asked him about his latest findings in the development of vaccines against malaria Professor Hill develops vaccines against malaria based on inducing cellular immune responses T lymphocytes instead of the more commonly used stimulation of antibodies Prophylactic vaccines developed in Oxford are now showing great promise in clinical trials Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/02_adrian_hill.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/02_adrian_hill.mp3 Progress in Malaria Vaccine Research Dr Simon Draper tells us about his progress in malaria vaccine research Dr Simon Draper s research interests include studies of vaccine induced malaria immunity His group focuses on translational medicine They will take their most promising vaccine candidates and manufacture them as clinical grade material The next step is proof of concept clinical trials in healthy volunteers Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/simon_draper.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/simon_draper.mp4 Malaria vaccine for P. vivax Dr Arturo Reyes Sandoval tells us about his research on a vaccine against Plasmodium vivax Dr Reyes Sandoval aims to develop a novel malaria vaccine against Plasmodium vivax one of the four malaria parasites that affect humans P vivax is found in Africa Asia Latin America and the Western Pacific 40 percent of the world s population is exposed to the disease that is responsible for around 130 to 350 million clinical cases every year Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/arturo_reyes-sandoval.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/arturo_reyes-sandoval.mp4 HIV Vaccine Development Professor Tomas Hanke tells us about his research on HIV vaccine development The long term aim for Professor Tom Hanke is to develop a safe effective and accessible HIV 1 vaccine His group tests novel ideas and vaccine strategies and focusses on a safe but rapid translation of the most promising laboratory results to phase I II clinical trials in human volunteers Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/38_tomas_hanke.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/38_tomas_hanke.mp4 Hepatitis C vaccine Dr Ellie Barnes talks about her research on Hepatitis C and her work on a T cell vaccine Dr Ellie Barnes aims to develop a prophylactic and a therapeutic hepatitis C virus vaccine to combat a global epidemic currently infecting 170 million people worldwide Many chronically infected patients silently develop complications of liver disease that can include hepatocellular cancer liver cirrhosis and liver failure Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/32_ellie_barnes.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/32_ellie_barnes.mp4 Aiming for a HIV vaccine Professor Sir Andrew McMichael tells us about recent developments in the search for a vaccine against HIV Prof Sir Andrew McMichael is working on human immunology and vaccines first looking at flu virus and now HIV His current lines of research include analysing early molecular events in HIV infection T cell immune response to HIV and the use of vaccination to control HIV infection Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/19_andrew_mcmichael.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/19_andrew_mcmichael.mp4 Malaria Vaccines Professor Adrian Hill has been studying the immune system and malaria susceptibility in African children for years We asked him about his latest findings in the development of vaccines against malaria Professor Hill develops vaccines against malaria based on inducing cellular immune responses T lymphocytes instead of the more commonly used stimulation of antibodies Prophylactic vaccines developed in Oxford are now showing great promise in clinical trials Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/02_adrian_hill.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/02_adrian_hill.mp4 A0000P0005 A Virbagen RCP cat vaccine http://www.flickr.com/photos/nottinghamvets/5791199066/ http://www.flickr.com/photos/nottinghamvets/5791199066/ The MMR vaccine: public health, private fears A decade ago the possibility of a link between the MMR vaccine and autism hit the media Fear of the vaccine spread rapidly and despite an almost unanimous consensus that the claim was unfounded still persists today In this unit we ll examine why this controversy took on such a life of its own and why parents still agonise about the vaccine http://dspace.jorum.ac.uk/xmlui/handle/10949/959 http://dspace.jorum.ac.uk/xmlui/handle/10949/959 A0000P0005 A Virbagen RCP cat vaccine https://www.flickr.com/photos/nottinghamvets/5791199066/ https://www.flickr.com/photos/nottinghamvets/5791199066/ Information to parents respecting the vaccine inoculation: or, the inoculation for cow-pox. By F. Skrimshire, M.D. Information to parents respecting the vaccine inoculation: or, the inoculation for cow-pox. By F. Skrimshire, M.D. ebook version of Information to parents respecting the vaccine inoculation or the inoculation for cow pox By F Skrimshire M D ebook version of Information to parents respecting the vaccine inoculation or the inoculation for cow pox By F Skrimshire M D http://ota.ox.ac.uk/id/5532 http://ota.ox.ac.uk/id/5532 20.462J Molecular Principles of Biomaterials (MIT) 20.462J Molecular Principles of Biomaterials (MIT) This course covers the analysis and design at a molecular scale of materials used in contact with biological systems including biotechnology and biomedical engineering Topics include molecular interactions between bio and synthetic molecules and surfaces design synthesis and processing approaches for materials that control cell functions and application of state of the art materials science to problems in tissue engineering drug delivery vaccines and cell guiding surfaces This course covers the analysis and design at a molecular scale of materials used in contact with biological systems including biotechnology and biomedical engineering Topics include molecular interactions between bio and synthetic molecules and surfaces design synthesis and processing approaches for materials that control cell functions and application of state of the art materials science to problems in tissue engineering drug delivery vaccines and cell guiding surfaces http://ocw.mit.edu/courses/biological-engineering/20-462j-molecular-principles-of-biomaterials-spring-2006 http://ocw.mit.edu/courses/biological-engineering/20-462j-molecular-principles-of-biomaterials-spring-2006 Can we eradicate Tuberculosis? Dr Helen Fletcher talks about progress in the development of a vaccine against tuberculosis Dr Helen Fletcher works on multi partner projects to discover biomarkers of protection from TB disease develop clinical trials capacity in Africa and develop new vaccines for TB Dr Fletcher has also developed her own research programme on transcriptional profiling of immune responses following both TB and malaria vaccination Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/helen_fletcher.mp3 http://media.podcasts.ox.ac.uk/clmed/translational/helen_fletcher.mp3 Can we eradicate Tuberculosis? Dr Helen Fletcher talks about progress in the development of a vaccine against tuberculosis Dr Helen Fletcher works on multi partner projects to discover biomarkers of protection from TB disease develop clinical trials capacity in Africa and develop new vaccines for TB Dr Fletcher has also developed her own research programme on transcriptional profiling of immune responses following both TB and malaria vaccination Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/helen_fletcher.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/helen_fletcher.mp4 Fighting to end Tuberculosis Helen McShane and Dr Helen Fletcher talk about a new TB vaccine currently being developed at Oxford s Wellcome Trust Centre that could become a more effective vaccine against Tuberculosis Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-video.mp4 http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-video.mp4 Fighting to end Tuberculosis Helen McShane and Dr Helen Fletcher talk about a new TB vaccine currently being developed at Oxford s Wellcome Trust Centre that could become a more effective vaccine against Tuberculosis Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-audio.mp3 http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-audio.mp3 B0017P0001 A kitten presenting for routine vaccination http://www.flickr.com/photos/nottinghamvets/5829846103/ http://www.flickr.com/photos/nottinghamvets/5829846103/ B0017P0002 A kitten presenting for routine vaccination http://www.flickr.com/photos/nottinghamvets/5830394606/ http://www.flickr.com/photos/nottinghamvets/5830394606/ B0017P0003 A kitten presenting for routine vaccination http://www.flickr.com/photos/nottinghamvets/5829845701/ http://www.flickr.com/photos/nottinghamvets/5829845701/ B0017P0004 A kitten presenting for routine vaccination http://www.flickr.com/photos/nottinghamvets/5829845313/ http://www.flickr.com/photos/nottinghamvets/5829845313/ B0024P0001 A kitten having a vaccination http://www.flickr.com/photos/nottinghamvets/5821978614/ http://www.flickr.com/photos/nottinghamvets/5821978614/ C0000P0066 http://www.flickr.com/photos/nottinghamvets/5812145941/ http://www.flickr.com/photos/nottinghamvets/5812145941/ C0000P0132 i CHPChlam http://www.flickr.com/photos/nottinghamvets/5807354359/ http://www.flickr.com/photos/nottinghamvets/5807354359/ A0000P0017 A Pfizer Vanguard 7 dog vaccine http://www.flickr.com/photos/nottinghamvets/5794765130/ http://www.flickr.com/photos/nottinghamvets/5794765130/ Developing an improved TB vaccine Dr McShane talks about the University s work in creating an improved vaccine against tuberculosis and she also talks about the urgency of this research http://media.podcasts.ox.ac.uk/alumni/weekend09/audio/mcshane-tb-medium-audio.pdf http://media.podcasts.ox.ac.uk/alumni/weekend09/audio/mcshane-tb-medium-audio.pdf HIV: Will there ever be a vaccine? A talk about the University s work in China and Africa and its attempts to identify the key determinants of protective immunology against HIV infection that should guide future vaccine design http://media.podcasts.ox.ac.uk/alumni/weekend09/audio/rowland-jones-hiv-medium-audio.pdf http://media.podcasts.ox.ac.uk/alumni/weekend09/audio/rowland-jones-hiv-medium-audio.pdf Fighting to end Tuberculosis Helen McShane and Dr Helen Fletcher talk about a new TB vaccine currently being developed at Oxford s Wellcome Trust Centre that could become a more effective vaccine against Tuberculosis http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-audio.pdf http://media.podcasts.ox.ac.uk/medsci/vaccination/wellcome-trust-medium-audio.pdf B0017P0001 A kitten presenting for routine vaccination https://www.flickr.com/photos/nottinghamvets/5829846103/ https://www.flickr.com/photos/nottinghamvets/5829846103/ B0017P0002 A kitten presenting for routine vaccination https://www.flickr.com/photos/nottinghamvets/5830394606/ https://www.flickr.com/photos/nottinghamvets/5830394606/ B0017P0003 A kitten presenting for routine vaccination https://www.flickr.com/photos/nottinghamvets/5829845701/ https://www.flickr.com/photos/nottinghamvets/5829845701/ B0017P0004 A kitten presenting for routine vaccination https://www.flickr.com/photos/nottinghamvets/5829845313/ https://www.flickr.com/photos/nottinghamvets/5829845313/ B0024P0001 A kitten having a vaccination https://www.flickr.com/photos/nottinghamvets/5821978614/ https://www.flickr.com/photos/nottinghamvets/5821978614/ C0000P0066 https://www.flickr.com/photos/nottinghamvets/5812145941/ https://www.flickr.com/photos/nottinghamvets/5812145941/ C0000P0132 i CHPChlam https://www.flickr.com/photos/nottinghamvets/5807354359/ https://www.flickr.com/photos/nottinghamvets/5807354359/ A0000P0017 A Pfizer Vanguard 7 dog vaccine https://www.flickr.com/photos/nottinghamvets/5794765130/ https://www.flickr.com/photos/nottinghamvets/5794765130/ The MMR vaccine: Public health, private fears A decade ago the possibility of a link between the MMR vaccine and autism hit the media Fear of the vaccine spread rapidly and despite an almost unanimous consensus that the claim was unfounded still persists today In this free course The MMR vaccine Public health private fears http://www.open.edu/openlearn/node/29884 http://www.open.edu/openlearn/node/29884 Malaria in Kenya There is a great need for better treatments for malaria and for a preventative malaria vaccine SPACIAL EPIDEMIOLOGY VACCINES Understanding the variation of malaria risk between houses villages or region and how malaria is transmitted in and around that variability helps develop better malaria control programmes and use their resources more wisely Since malaria control tools are becoming less effective with time progress in vaccine design is essential Wales http creativecommons org licenses by nc sa 2 0 uk http://media.podcasts.ox.ac.uk/clmed/translational/philip-bejon-malaria-kenya-hd_0.mp4 http://media.podcasts.ox.ac.uk/clmed/translational/philip-bejon-malaria-kenya-hd_0.mp4